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The map label for this gene is bah [H]

Identifier: 83719676

GI number: 83719676

Start: 613544

End: 614509

Strand: Direct

Name: bah [H]

Synonym: BTH_I0539

Alternate gene names: 83719676

Gene position: 613544-614509 (Clockwise)

Preceding gene: 83720842

Following gene: 83718792

Centisome position: 16.11

GC content: 73.19

Gene sequence:

>966_bases
ATGAGTTGGCAGAGCAAAGTCGCGTGCTGGCTGCTGCGCCGGCAGTTTCGTCCTGAGACGCTGCGCCCCGTGATCGACCC
GGCTCGCGCGCGGCGGCTGACGAAGCTGCGGATGCGCGTGCCGCGCCGCCCGCCCGCCGGCTGGCGGCTGCGCGAGCGCT
ACGGCGCCGGCGACGCGCCGCTGCGCGGCGAATGGCTCGAGCGCACGGACGCCGTGCCCGTTCGCGCGAAGCATGGCCGG
ATGCTGCTGTATTTCCACGGCGGCGGTTATTACTTCTGCTCGCCTCAGACGCACCGCCCGCTCGTGTTCGCGCTGACGCG
GCACGCGGGCGTGCGCTCGTTCTCGCTCGACTACCGGCTCGCACCCGAGCATCCGTTTCCGGCCGCGCTCGACGACGCGC
TCGCCGCGTACCGGCAACTCGTGTCCGCCGGCACGCCGCCGGAGTCGATCGTGTTCGGCGGCGATTCGGCGGGCGGCGGC
CTCGCGCTCGCCGCGCTCGTCGCGCTGCGCGACGCGGGCGACCCGCTGCCGGCGGGCGCGGTGCTGTTCTCGCCGTGGAC
CGATCTCGCCGCGACGGGCGATACGCTGCGCACGCACGACGGGCTCGATCCGATGTTCGCGGGCGCGGCGCTCGGCCGCG
CGGCGCGCCTGTATCTCGGCGACACGCCGGGCACGCATCCGCATGCGTCGCCGCTGTATGCGGATTTCACGGGATTGCCG
CCGCTTTTCATCCAGGCGGGCAGCACCGAGGTGCTGCTCGACGATTCGCGGCGCGTCGCCGACAAGGCGCGAGCGGCGGG
CGTGCACGTCGAACTGGAGATATGGCCGCAGATGCCGCACGTATGGCAGATCTACGTGCCGTTCGTGCCCGAATCGGCGC
GTGCGCTCGAGCGGGCGGCCGCGTTCGTGCGGCGCATCGCGGTCGAGCGCGCGACTCAGCGCACGGCCGACGCGTCGATC
GCCTGA

Upstream 100 bases:

>100_bases
GGCGAACTGAGCCGCGCCGCCGGATTTAGAGGACCCGATCGACGGACGCGCGCCGGAACGCACGTAGTATCGTCACATTT
ACCGGTTCGGAGTGCGTTCG

Downstream 100 bases:

>100_bases
TACGCGGCCTTCACGGCCGTCTGCCCGTACTTGCGCTCGAGCCGGCGCACCGCGAAGTGTCCGTGCGCGGCCTGCTGGAA
ATGGTCGATGAAGAGCGTGT

Product: esterase

Products: alcohol; a carboxylate [C]

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MSWQSKVACWLLRRQFRPETLRPVIDPARARRLTKLRMRVPRRPPAGWRLRERYGAGDAPLRGEWLERTDAVPVRAKHGR
MLLYFHGGGYYFCSPQTHRPLVFALTRHAGVRSFSLDYRLAPEHPFPAALDDALAAYRQLVSAGTPPESIVFGGDSAGGG
LALAALVALRDAGDPLPAGAVLFSPWTDLAATGDTLRTHDGLDPMFAGAALGRAARLYLGDTPGTHPHASPLYADFTGLP
PLFIQAGSTEVLLDDSRRVADKARAAGVHVELEIWPQMPHVWQIYVPFVPESARALERAAAFVRRIAVERATQRTADASI
A

Sequences:

>Translated_321_residues
MSWQSKVACWLLRRQFRPETLRPVIDPARARRLTKLRMRVPRRPPAGWRLRERYGAGDAPLRGEWLERTDAVPVRAKHGR
MLLYFHGGGYYFCSPQTHRPLVFALTRHAGVRSFSLDYRLAPEHPFPAALDDALAAYRQLVSAGTPPESIVFGGDSAGGG
LALAALVALRDAGDPLPAGAVLFSPWTDLAATGDTLRTHDGLDPMFAGAALGRAARLYLGDTPGTHPHASPLYADFTGLP
PLFIQAGSTEVLLDDSRRVADKARAAGVHVELEIWPQMPHVWQIYVPFVPESARALERAAAFVRRIAVERATQRTADASI
A
>Mature_320_residues
SWQSKVACWLLRRQFRPETLRPVIDPARARRLTKLRMRVPRRPPAGWRLRERYGAGDAPLRGEWLERTDAVPVRAKHGRM
LLYFHGGGYYFCSPQTHRPLVFALTRHAGVRSFSLDYRLAPEHPFPAALDDALAAYRQLVSAGTPPESIVFGGDSAGGGL
ALAALVALRDAGDPLPAGAVLFSPWTDLAATGDTLRTHDGLDPMFAGAALGRAARLYLGDTPGTHPHASPLYADFTGLPP
LFIQAGSTEVLLDDSRRVADKARAAGVHVELEIWPQMPHVWQIYVPFVPESARALERAAAFVRRIAVERATQRTADASIA

Specific function: This protein removes the N-acetyl group from bialaphos as one of the final steps of the bialaphos biosynthetic pathway [H]

COG id: COG0657

COG function: function code I; Esterase/lipase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'GDXG' lipolytic enzyme family [H]

Homologues:

Organism=Homo sapiens, GI21328446, Length=165, Percent_Identity=31.5151515151515, Blast_Score=76, Evalue=4e-14,
Organism=Escherichia coli, GI1786682, Length=321, Percent_Identity=27.4143302180685, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17567059, Length=342, Percent_Identity=23.3918128654971, Blast_Score=78, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013094
- InterPro:   IPR002168 [H]

Pfam domain/function: PF07859 Abhydrolase_3 [H]

EC number: 3.1.1.- [C]

Molecular weight: Translated: 35205; Mature: 35073

Theoretical pI: Translated: 10.21; Mature: 10.21

Prosite motif: PS01173 LIPASE_GDXG_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWQSKVACWLLRRQFRPETLRPVIDPARARRLTKLRMRVPRRPPAGWRLRERYGAGDAP
CCCHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCC
LRGEWLERTDAVPVRAKHGRMLLYFHGGGYYFCSPQTHRPLVFALTRHAGVRSFSLDYRL
CCCHHHHHCCCCCEEECCCCEEEEEECCEEEEECCCCCCCEEEEEECCCCCEEEEECEEE
APEHPFPAALDDALAAYRQLVSAGTPPESIVFGGDSAGGGLALAALVALRDAGDPLPAGA
CCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCE
VLFSPWTDLAATGDTLRTHDGLDPMFAGAALGRAARLYLGDTPGTHPHASPLYADFTGLP
EEECCCHHHHCCCCCCCCCCCCCHHHHHHHHCCEEEEEECCCCCCCCCCCCCEECCCCCC
PLFIQAGSTEVLLDDSRRVADKARAAGVHVELEIWPQMPHVWQIYVPFVPESARALERAA
CEEEECCCEEEEECCCHHHHHHHHHCCEEEEEEECCCCCCEEEEEEECCCCHHHHHHHHH
AFVRRIAVERATQRTADASIA
HHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SWQSKVACWLLRRQFRPETLRPVIDPARARRLTKLRMRVPRRPPAGWRLRERYGAGDAP
CCHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCC
LRGEWLERTDAVPVRAKHGRMLLYFHGGGYYFCSPQTHRPLVFALTRHAGVRSFSLDYRL
CCCHHHHHCCCCCEEECCCCEEEEEECCEEEEECCCCCCCEEEEEECCCCCEEEEECEEE
APEHPFPAALDDALAAYRQLVSAGTPPESIVFGGDSAGGGLALAALVALRDAGDPLPAGA
CCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCE
VLFSPWTDLAATGDTLRTHDGLDPMFAGAALGRAARLYLGDTPGTHPHASPLYADFTGLP
EEECCCHHHHCCCCCCCCCCCCCHHHHHHHHCCEEEEEECCCCCCCCCCCCCEECCCCCC
PLFIQAGSTEVLLDDSRRVADKARAAGVHVELEIWPQMPHVWQIYVPFVPESARALERAA
CEEEECCCEEEEECCCHHHHHHHHHCCEEEEEEECCCCCCEEEEEEECCCCHHHHHHHHH
AFVRRIAVERATQRTADASIA
HHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Carboxylic ester; H2O [C]

Specific reaction: Carboxylic ester + H2O = an alcohol + carboxylate [C]

General reaction: Hydrolase; Acting on ester bonds; Carboxylic ester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2066341 [H]