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The map label for this gene is moaE [H]

Identifier: 83719603

GI number: 83719603

Start: 2477997

End: 2478497

Strand: Direct

Name: moaE [H]

Synonym: BTH_I2202

Alternate gene names: 83719603

Gene position: 2477997-2478497 (Clockwise)

Preceding gene: 83720736

Following gene: 83721287

Centisome position: 65.05

GC content: 69.06

Gene sequence:

>501_bases
ATGGCGACGGTACGGGTGCAGACGGACGATTTCGACGTGAGCGCCGAGATCGCGGCGTTGCGCGCGCGCAATCCGAAAGT
GGGCGCGGTTGCGTGCTTCGTCGGCACGGTGCGCGATTTGAACGAGGGCGAGCAGGTCGACGCGCTCGAGCTCGAGCACT
ATCCGGGCATGACCGAGAAGGCGCTCGCCGCGATCGCGGACGATGCGATCGCGCGCTGGCCGGGCATCGATGTCGCGATC
GTTCACCGGGTCGGCAAGCTCCGTCCGCTCGATCAGATCGTGTTCGTCGCGACCGTGTCCGCGCATCGCGGCGACGCGTT
CCAGTCGTGCGAGTTCGTGATGGATTACCTGAAGACGCAGGCGCCGTTCTGGAAGAAGGAGAACACGCCCGCGGGCGAGC
GCTGGGTGGACGCGCGCCGCGCCGACGACGCGGCGCTCGCGCGCTGGGGCGTCGAATCGGGAAACGCGGGGCGCGCGGGG
AACGCGAAGCGGTCGACGTAG

Upstream 100 bases:

>100_bases
ATGGCGTGCAACCATACGATGACGGACGCCGGCACGCGGATCACCGACGGCTGCGAGGTCGCGTTCTTCCCGCCGGTGAC
GGGCGGCTGAGGAGGCGGCG

Downstream 100 bases:

>100_bases
GCGCGCCAAGCACCGCTTTCGCCCGGCCGGATCGCAGTGCCGGGTGGTCGCCGGCCGCGCTGGGCGCGGCCGGCGGAGAG
CATGTTTTCCGTGTTCGGGG

Product: molybdopterin converting factor subunit 2

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 166; Mature: 165

Protein sequence:

>166_residues
MATVRVQTDDFDVSAEIAALRARNPKVGAVACFVGTVRDLNEGEQVDALELEHYPGMTEKALAAIADDAIARWPGIDVAI
VHRVGKLRPLDQIVFVATVSAHRGDAFQSCEFVMDYLKTQAPFWKKENTPAGERWVDARRADDAALARWGVESGNAGRAG
NAKRST

Sequences:

>Translated_166_residues
MATVRVQTDDFDVSAEIAALRARNPKVGAVACFVGTVRDLNEGEQVDALELEHYPGMTEKALAAIADDAIARWPGIDVAI
VHRVGKLRPLDQIVFVATVSAHRGDAFQSCEFVMDYLKTQAPFWKKENTPAGERWVDARRADDAALARWGVESGNAGRAG
NAKRST
>Mature_165_residues
ATVRVQTDDFDVSAEIAALRARNPKVGAVACFVGTVRDLNEGEQVDALELEHYPGMTEKALAAIADDAIARWPGIDVAIV
HRVGKLRPLDQIVFVATVSAHRGDAFQSCEFVMDYLKTQAPFWKKENTPAGERWVDARRADDAALARWGVESGNAGRAGN
AKRST

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=112, Percent_Identity=34.8214285714286, Blast_Score=83, Evalue=1e-16,
Organism=Escherichia coli, GI1787003, Length=139, Percent_Identity=56.1151079136691, Blast_Score=160, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI17509279, Length=111, Percent_Identity=35.1351351351351, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21356259, Length=128, Percent_Identity=36.71875, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 18065; Mature: 17934

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATVRVQTDDFDVSAEIAALRARNPKVGAVACFVGTVRDLNEGEQVDALELEHYPGMTEK
CCEEEEECCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCEEECCCCCCCHHH
ALAAIADDAIARWPGIDVAIVHRVGKLRPLDQIVFVATVSAHRGDAFQSCEFVMDYLKTQ
HHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHEEEEEEECCCCCCHHHHHHHHHHHHHHC
APFWKKENTPAGERWVDARRADDAALARWGVESGNAGRAGNAKRST
CCCCCCCCCCCCHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ATVRVQTDDFDVSAEIAALRARNPKVGAVACFVGTVRDLNEGEQVDALELEHYPGMTEK
CEEEEECCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCEEECCCCCCCHHH
ALAAIADDAIARWPGIDVAIVHRVGKLRPLDQIVFVATVSAHRGDAFQSCEFVMDYLKTQ
HHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHEEEEEEECCCCCCHHHHHHHHHHHHHHC
APFWKKENTPAGERWVDARRADDAALARWGVESGNAGRAGNAKRST
CCCCCCCCCCCCHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]