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The map label for this gene is atzB [H]

Identifier: 83719602

GI number: 83719602

Start: 2347153

End: 2348565

Strand: Direct

Name: atzB [H]

Synonym: BTH_I2073

Alternate gene names: 83719602

Gene position: 2347153-2348565 (Clockwise)

Preceding gene: 83719282

Following gene: 83721180

Centisome position: 61.62

GC content: 70.13

Gene sequence:

>1413_bases
ATGGAGCGATACTCGAGCGCGCGCGCCGGCGCGCAATCCCAATCCCCGAACCGGCCGAGGACGCTCGTCGTCAAGCATGC
CGACGTGCTCGTGACGATGGACGGCGCGCGCCGCGAGCTGCGCGACGCGGGCCTGTACGTCGAGGACAACCGGATCGTCG
CGGTCGGGCCGAGCGCCGAGCTGCCCGCGCAGGCGGACGAAGTGCTCGATTTGCGCGGCCATCTCGTGATCCCGGGGCTC
GTCAACACGCATCATCATATGTATCAGAGCCTCACGCGCGCGATCCCCGCCGCGCAGAACGCCGAGCTGTTCGGCTGGCT
CACGAATCTATACCGGATCTGGGCGCACCTGACGCCGGAGATGATCGAGGTGTCGGCGCTGACCGCGATGGCGGAGCTGC
TGCTGTCCGGCTGCACGACGTCGAGCGATCATCTGTACATCTATCCGAACGGCAGCCGGCTCGACGACAGCGTTGCGGCC
GCGCAGCGCATCGGCATGCGCTTTCACGCGAGCCGCGGCAGCATGAGCGTCGGGCAGCGCGACGGCGGGCTGCCGCCCGA
CTCGGTCGTCGAGCGTGAGCCGGATATCCTGCGCGACACGCAGCGCGTGATCGAGACCTACCATGACGAAGGCCGCTATG
CGATGCTGCGCGTCGTCGTCGCGCCGTGTTCGCCGTTCTCGGTGAGCCGCGGCTTGATGCGCGACGCGGCGGCGCTCGCG
CGTGAGCATCGCGTGTCGCTGCACACGCATCTCGCGGAGAACGCGAACGACGTCGCATACAGCCGCGAGACATTCGGGAT
GACGCCCGCCGAATATGCGGAGGATCTCGGCTGGGTCGGGCGCGACGTGTGGCATGCGCACTGCGTGCAACTGGACGAAT
CCGGCATCGCGCTTTTCGCGCGGACCGGCACGGGCGTCGCGCATTGCCCATGCTCGAACATGCGGCTTGCGTCCGGGATC
GCGCCCGTCGCGCGGATGCGCGTTGCGGGCGTGCCGGTCGGGCTGGGCGTCGACGGCAGCGCGTCGAACGACGGCGCGCA
GATGGTCGCCGAGGTACGGCAGGCGCTGTTGCTGCAGCGCGTCGGATTCGGCCCGGACGCGATGACCGCGCGCGATGCGC
TCGAGATCGCGACGCTCGGCGGCGCACGCGTGCTGAACCGCGACGACATCGGCGCGCTCGCGCCCGGCATGGCGGCGGAT
TTCGTCGCGTTCGATCTGCGCACGCCGCAGTTCGCGGGCGCGCTGCACGATCCCGTCGCGGCGCTCGTGTTCTGCGCGCC
GTCGCAGGCGGCGTACAGCGTCGTCAACGGACGCGTCGTCGTGCGGGAAGGGCGGCTGACGGCGTTCGAGATCGAGCCGC
TCGTCGAGCGGCACAACGCGCTCGCGAAGGCGCTTTGCGAGGCGGCGCGCTGA

Upstream 100 bases:

>100_bases
GACGCGGCGGCGCGGTGGTGCCGGGCGCCGCGTTCGAGCGTTCGAACATTCGAGCAGAGAGGCCGCCTCGGCGGCGCAAC
GACACGGAGATCGAACGACG

Downstream 100 bases:

>100_bases
GCGGCGCGGCTGCGGGCGGTTCGGCGCGGGCTTGGCCGTGCGCCGGGCGCGCGGATGCGCATGCGTTCGTACGGATTCGA
CTGCCCCCGCGATGGCTGTA

Product: hydroxydechloroatrazine ethylaminohydrolase

Products: NA

Alternate protein names: Hydroxyatrazine hydrolase [H]

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MERYSSARAGAQSQSPNRPRTLVVKHADVLVTMDGARRELRDAGLYVEDNRIVAVGPSAELPAQADEVLDLRGHLVIPGL
VNTHHHMYQSLTRAIPAAQNAELFGWLTNLYRIWAHLTPEMIEVSALTAMAELLLSGCTTSSDHLYIYPNGSRLDDSVAA
AQRIGMRFHASRGSMSVGQRDGGLPPDSVVEREPDILRDTQRVIETYHDEGRYAMLRVVVAPCSPFSVSRGLMRDAAALA
REHRVSLHTHLAENANDVAYSRETFGMTPAEYAEDLGWVGRDVWHAHCVQLDESGIALFARTGTGVAHCPCSNMRLASGI
APVARMRVAGVPVGLGVDGSASNDGAQMVAEVRQALLLQRVGFGPDAMTARDALEIATLGGARVLNRDDIGALAPGMAAD
FVAFDLRTPQFAGALHDPVAALVFCAPSQAAYSVVNGRVVVREGRLTAFEIEPLVERHNALAKALCEAAR

Sequences:

>Translated_470_residues
MERYSSARAGAQSQSPNRPRTLVVKHADVLVTMDGARRELRDAGLYVEDNRIVAVGPSAELPAQADEVLDLRGHLVIPGL
VNTHHHMYQSLTRAIPAAQNAELFGWLTNLYRIWAHLTPEMIEVSALTAMAELLLSGCTTSSDHLYIYPNGSRLDDSVAA
AQRIGMRFHASRGSMSVGQRDGGLPPDSVVEREPDILRDTQRVIETYHDEGRYAMLRVVVAPCSPFSVSRGLMRDAAALA
REHRVSLHTHLAENANDVAYSRETFGMTPAEYAEDLGWVGRDVWHAHCVQLDESGIALFARTGTGVAHCPCSNMRLASGI
APVARMRVAGVPVGLGVDGSASNDGAQMVAEVRQALLLQRVGFGPDAMTARDALEIATLGGARVLNRDDIGALAPGMAAD
FVAFDLRTPQFAGALHDPVAALVFCAPSQAAYSVVNGRVVVREGRLTAFEIEPLVERHNALAKALCEAAR
>Mature_470_residues
MERYSSARAGAQSQSPNRPRTLVVKHADVLVTMDGARRELRDAGLYVEDNRIVAVGPSAELPAQADEVLDLRGHLVIPGL
VNTHHHMYQSLTRAIPAAQNAELFGWLTNLYRIWAHLTPEMIEVSALTAMAELLLSGCTTSSDHLYIYPNGSRLDDSVAA
AQRIGMRFHASRGSMSVGQRDGGLPPDSVVEREPDILRDTQRVIETYHDEGRYAMLRVVVAPCSPFSVSRGLMRDAAALA
REHRVSLHTHLAENANDVAYSRETFGMTPAEYAEDLGWVGRDVWHAHCVQLDESGIALFARTGTGVAHCPCSNMRLASGI
APVARMRVAGVPVGLGVDGSASNDGAQMVAEVRQALLLQRVGFGPDAMTARDALEIATLGGARVLNRDDIGALAPGMAAD
FVAFDLRTPQFAGALHDPVAALVFCAPSQAAYSVVNGRVVVREGRLTAFEIEPLVERHNALAKALCEAAR

Specific function: Catalyzes the deamination reaction of hydroxyatrazine to N-isopropylammelide (dihydroxy-isopropyl-atrazine). The enzyme is also capable of catalyzing some dechlorinating reactions [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATZ/TRZ family [H]

Homologues:

Organism=Homo sapiens, GI4758426, Length=381, Percent_Identity=23.8845144356955, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI1789249, Length=445, Percent_Identity=27.6404494382022, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI87082177, Length=424, Percent_Identity=25.4716981132075, Blast_Score=86, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17540282, Length=441, Percent_Identity=22.9024943310658, Blast_Score=95, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6319963, Length=346, Percent_Identity=25.1445086705202, Blast_Score=94, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24643849, Length=239, Percent_Identity=26.7782426778243, Blast_Score=84, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.99.3 [H]

Molecular weight: Translated: 50661; Mature: 50661

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERYSSARAGAQSQSPNRPRTLVVKHADVLVTMDGARRELRDAGLYVEDNRIVAVGPSAE
CCCCCCHHCCCCCCCCCCCCEEEEEECEEEEEECCHHHHHHHCCCEEECCEEEEECCCCC
LPAQADEVLDLRGHLVIPGLVNTHHHMYQSLTRAIPAAQNAELFGWLTNLYRIWAHLTPE
CCCCHHHHHHCCCCEEECCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHH
MIEVSALTAMAELLLSGCTTSSDHLYIYPNGSRLDDSVAAAQRIGMRFHASRGSMSVGQR
HHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHCCEEECCCCCCCCCCC
DGGLPPDSVVEREPDILRDTQRVIETYHDEGRYAMLRVVVAPCSPFSVSRGLMRDAAALA
CCCCCCHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHH
REHRVSLHTHLAENANDVAYSRETFGMTPAEYAEDLGWVGRDVWHAHCVQLDESGIALFA
HHHHHHHHHHHHCCCCHHEECHHHCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEE
RTGTGVAHCPCSNMRLASGIAPVARMRVAGVPVGLGVDGSASNDGAQMVAEVRQALLLQR
ECCCCEEECCCCCCCHHHCCCHHHHHHHCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHH
VGFGPDAMTARDALEIATLGGARVLNRDDIGALAPGMAADFVAFDLRTPQFAGALHDPVA
CCCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCCCCCHHHHEEEECCCCHHHCHHHHHHH
ALVFCAPSQAAYSVVNGRVVVREGRLTAFEIEPLVERHNALAKALCEAAR
HHEEECCCHHHHHHHCCEEEEEECCEEEEEHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MERYSSARAGAQSQSPNRPRTLVVKHADVLVTMDGARRELRDAGLYVEDNRIVAVGPSAE
CCCCCCHHCCCCCCCCCCCCEEEEEECEEEEEECCHHHHHHHCCCEEECCEEEEECCCCC
LPAQADEVLDLRGHLVIPGLVNTHHHMYQSLTRAIPAAQNAELFGWLTNLYRIWAHLTPE
CCCCHHHHHHCCCCEEECCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHH
MIEVSALTAMAELLLSGCTTSSDHLYIYPNGSRLDDSVAAAQRIGMRFHASRGSMSVGQR
HHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHCCEEECCCCCCCCCCC
DGGLPPDSVVEREPDILRDTQRVIETYHDEGRYAMLRVVVAPCSPFSVSRGLMRDAAALA
CCCCCCHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHH
REHRVSLHTHLAENANDVAYSRETFGMTPAEYAEDLGWVGRDVWHAHCVQLDESGIALFA
HHHHHHHHHHHHCCCCHHEECHHHCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEE
RTGTGVAHCPCSNMRLASGIAPVARMRVAGVPVGLGVDGSASNDGAQMVAEVRQALLLQR
ECCCCEEECCCCCCCHHHCCCHHHHHHHCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHH
VGFGPDAMTARDALEIATLGGARVLNRDDIGALAPGMAADFVAFDLRTPQFAGALHDPVA
CCCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCCCCCHHHHEEEECCCCHHHCHHHHHHH
ALVFCAPSQAAYSVVNGRVVVREGRLTAFEIEPLVERHNALAKALCEAAR
HHEEECCCHHHHHHHCCEEEEEECCEEEEEHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9055410 [H]