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The map label for this gene is rnhA [H]

Identifier: 83719592

GI number: 83719592

Start: 3206001

End: 3206447

Strand: Direct

Name: rnhA [H]

Synonym: BTH_I2790

Alternate gene names: 83719592

Gene position: 3206001-3206447 (Clockwise)

Preceding gene: 83718692

Following gene: 83720697

Centisome position: 84.16

GC content: 65.77

Gene sequence:

>447_bases
ATGACGTTGCAAACCATCGACATCTATACCGACGGCGCCTGCAAGGGCAATCCGGGCCCCGGCGGCTGGGGCGCGCTGCT
GCGCTACGGCGCGCAGGAGAAAGAACTCTTCGGCGGCGAAGCCGGCACGACCAACAACCGGATGGAGCTCACCGCGGTGA
TCGCCGCGCTCGAGGCGCTCAAGCGCCCGTGCAAGGTGGTCGTCCACACCGATTCGCAATACGTGCAGAAAGGCATCAGC
GAATGGATCCACGGCTGGAAGAAAAAAGGCTGGGTCACCGCCGCGAAGACGCCCGTGAAGAACGCGGACCTCTGGCAGAA
ACTCGACGCGCTCGTCGCGCAGCACGACGTCGAATGGCGCTGGGTGAAGGGGCACGCCGGCCATCCGGAGAACGAACGCG
CTGACGCGCTCGCGAACCGCGGCGTCGAATCGCTCGCGCAGGCATGA

Upstream 100 bases:

>100_bases
TGCGCGGGATGCGGCTCGTCGGCCCGATCAAGATGAAAAAACCGGTGCTCGCGCCGGGCCTCACGCCCGCCGCCACCCCG
ACCACCCACCAAGAACATTC

Downstream 100 bases:

>100_bases
GCCGGCTCGCGCGCCCCGTCCCACTTCACGACTGACTCGAATTCTCCATTCTTCCGACATGCGCCAGATCATTCTCGATA
CCGAAACCACCGGCCTGAAC

Product: RNase H

Products: NA

Alternate protein names: RNase H [H]

Number of amino acids: Translated: 148; Mature: 147

Protein sequence:

>148_residues
MTLQTIDIYTDGACKGNPGPGGWGALLRYGAQEKELFGGEAGTTNNRMELTAVIAALEALKRPCKVVVHTDSQYVQKGIS
EWIHGWKKKGWVTAAKTPVKNADLWQKLDALVAQHDVEWRWVKGHAGHPENERADALANRGVESLAQA

Sequences:

>Translated_148_residues
MTLQTIDIYTDGACKGNPGPGGWGALLRYGAQEKELFGGEAGTTNNRMELTAVIAALEALKRPCKVVVHTDSQYVQKGIS
EWIHGWKKKGWVTAAKTPVKNADLWQKLDALVAQHDVEWRWVKGHAGHPENERADALANRGVESLAQA
>Mature_147_residues
TLQTIDIYTDGACKGNPGPGGWGALLRYGAQEKELFGGEAGTTNNRMELTAVIAALEALKRPCKVVVHTDSQYVQKGISE
WIHGWKKKGWVTAAKTPVKNADLWQKLDALVAQHDVEWRWVKGHAGHPENERADALANRGVESLAQA

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids [H]

COG id: COG0328

COG function: function code L; Ribonuclease HI

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase H domain [H]

Homologues:

Organism=Homo sapiens, GI21359816, Length=149, Percent_Identity=36.9127516778523, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI1786408, Length=136, Percent_Identity=64.7058823529412, Blast_Score=197, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI115532542, Length=143, Percent_Identity=40.5594405594406, Blast_Score=99, Evalue=6e-22,
Organism=Drosophila melanogaster, GI45552509, Length=143, Percent_Identity=36.3636363636364, Blast_Score=80, Evalue=7e-16,
Organism=Drosophila melanogaster, GI17137476, Length=141, Percent_Identity=36.8794326241135, Blast_Score=79, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022892
- InterPro:   IPR012337
- InterPro:   IPR002156 [H]

Pfam domain/function: PF00075 RnaseH [H]

EC number: =3.1.26.4 [H]

Molecular weight: Translated: 16200; Mature: 16069

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: PS50879 RNASE_H

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLQTIDIYTDGACKGNPGPGGWGALLRYGAQEKELFGGEAGTTNNRMELTAVIAALEAL
CCCEEEEEEECCCCCCCCCCCHHHHHHHCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHH
KRPCKVVVHTDSQYVQKGISEWIHGWKKKGWVTAAKTPVKNADLWQKLDALVAQHDVEWR
CCCCEEEEECCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHHCCCCEE
WVKGHAGHPENERADALANRGVESLAQA
EEECCCCCCCCHHHHHHHHCCHHHHHCC
>Mature Secondary Structure 
TLQTIDIYTDGACKGNPGPGGWGALLRYGAQEKELFGGEAGTTNNRMELTAVIAALEAL
CCEEEEEEECCCCCCCCCCCHHHHHHHCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHH
KRPCKVVVHTDSQYVQKGISEWIHGWKKKGWVTAAKTPVKNADLWQKLDALVAQHDVEWR
CCCCEEEEECCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHHCCCCEE
WVKGHAGHPENERADALANRGVESLAQA
EEECCCCCCCCHHHHHHHHCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]