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The map label for this gene is map-1 [H]

Identifier: 83719494

GI number: 83719494

Start: 2236784

End: 2237611

Strand: Direct

Name: map-1 [H]

Synonym: BTH_I1973

Alternate gene names: 83719494

Gene position: 2236784-2237611 (Clockwise)

Preceding gene: 83720679

Following gene: 83721383

Centisome position: 58.72

GC content: 69.2

Gene sequence:

>828_bases
ATGGCGCGTTCACGACACGTTCCGATCCGCACGCAAGCCGAGATCGCGATGGCGCGCCGCGCCGGCACGATGGCGGCGCG
GGTGTTGGGCATGATCGCGCCGCACGTGAAGGCTGGCGTGACGACGAACGAGCTCGACCGGCTATGCCGCGAGTACATCG
TCGACATCCTGCGCGCGCGGCCCGCGAACATCGGCTATCACGGGTATCCGAAGACGATCTGCGCATCCGTGAACCACGTG
GTCTGCCACGGCATTCCGTCCGATCACGCATTGAAGGACGGCGACATCATCAATATCGACGTCGCGCTCGACAGCGACGG
CTGGTACGGCGACACGAGCCGCATGTACTTCGTCGGCGAGCCGGCTGAGCCGGCTCGGCGTCTCGTCGATGCGACGTATG
AGGCGATGATGGCGGGCGTCGCGGCGGTGCGCCCGGGCGCGACGCTCGGCGACGTCGGCCACGCGATCCAGAGCGTCGCG
CATCGCGAGGGCTTCAGCGTCGTACGCGAGTATTGCGGCCACGGCATCGGCCGCATCTACCACGACGAGCCGCAAGTGCT
CCATTACGGCCGTCCGGGCACGGGGCTGCGTCTCGCGCCCGGGATGATCTTCACGATCGAGCCGATGCTCAATGCGGGGC
GCGCCGAAACGCGGCAGCTCGCCGACGGCTGGACGGTCGTCACGCAGGATCGCTCGTGGTCCGCGCAGTGGGAGCATATG
GTCGTCGTGACGGAAGACGGCTTCGACATCCTGACGCCGTGGCCGGACGCAGCGCCCGAGCGGTCGCCCGTGACGGCGCG
CGCGGCCGGCGCGCCCGAGCGCGGCTGA

Upstream 100 bases:

>100_bases
ATCCGGCGCTGACCTATGCGGAGATTTGCCGGCTGTTGATCGAGACGGAAATCCATGGCGACGAAGCGGCGCCGGCCGTC
GACGCCGCGAGGAGCGCATG

Downstream 100 bases:

>100_bases
ATCGGCCGTCGACTGGCGGCTCGGCGCGAGGGCGCGCGGCGCGCGGGCGTTTGCGAAGCGCGCGTGCGCATCGCATCGGC
GCTCGCGCGCCGCGCGTCCG

Product: methionine aminopeptidase, type I

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MARSRHVPIRTQAEIAMARRAGTMAARVLGMIAPHVKAGVTTNELDRLCREYIVDILRARPANIGYHGYPKTICASVNHV
VCHGIPSDHALKDGDIINIDVALDSDGWYGDTSRMYFVGEPAEPARRLVDATYEAMMAGVAAVRPGATLGDVGHAIQSVA
HREGFSVVREYCGHGIGRIYHDEPQVLHYGRPGTGLRLAPGMIFTIEPMLNAGRAETRQLADGWTVVTQDRSWSAQWEHM
VVVTEDGFDILTPWPDAAPERSPVTARAAGAPERG

Sequences:

>Translated_275_residues
MARSRHVPIRTQAEIAMARRAGTMAARVLGMIAPHVKAGVTTNELDRLCREYIVDILRARPANIGYHGYPKTICASVNHV
VCHGIPSDHALKDGDIINIDVALDSDGWYGDTSRMYFVGEPAEPARRLVDATYEAMMAGVAAVRPGATLGDVGHAIQSVA
HREGFSVVREYCGHGIGRIYHDEPQVLHYGRPGTGLRLAPGMIFTIEPMLNAGRAETRQLADGWTVVTQDRSWSAQWEHM
VVVTEDGFDILTPWPDAAPERSPVTARAAGAPERG
>Mature_274_residues
ARSRHVPIRTQAEIAMARRAGTMAARVLGMIAPHVKAGVTTNELDRLCREYIVDILRARPANIGYHGYPKTICASVNHVV
CHGIPSDHALKDGDIINIDVALDSDGWYGDTSRMYFVGEPAEPARRLVDATYEAMMAGVAAVRPGATLGDVGHAIQSVAH
REGFSVVREYCGHGIGRIYHDEPQVLHYGRPGTGLRLAPGMIFTIEPMLNAGRAETRQLADGWTVVTQDRSWSAQWEHMV
VVTEDGFDILTPWPDAAPERSPVTARAAGAPERG

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=256, Percent_Identity=40.625, Blast_Score=205, Evalue=3e-53,
Organism=Homo sapiens, GI40385867, Length=252, Percent_Identity=38.8888888888889, Blast_Score=195, Evalue=3e-50,
Organism=Escherichia coli, GI1786364, Length=251, Percent_Identity=55.7768924302789, Blast_Score=294, Evalue=5e-81,
Organism=Caenorhabditis elegans, GI71996291, Length=258, Percent_Identity=38.3720930232558, Blast_Score=192, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6323273, Length=258, Percent_Identity=38.3720930232558, Blast_Score=207, Evalue=2e-54,
Organism=Drosophila melanogaster, GI21355531, Length=250, Percent_Identity=41.6, Blast_Score=208, Evalue=3e-54,
Organism=Drosophila melanogaster, GI24583427, Length=244, Percent_Identity=39.344262295082, Blast_Score=192, Evalue=2e-49,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 29953; Mature: 29822

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00680 MAP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARSRHVPIRTQAEIAMARRAGTMAARVLGMIAPHVKAGVTTNELDRLCREYIVDILRAR
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHCC
PANIGYHGYPKTICASVNHVVCHGIPSDHALKDGDIINIDVALDSDGWYGDTSRMYFVGE
CCCCCCCCCCHHHHHCCCEEEEECCCCCCCCCCCCEEEEEEEECCCCCCCCCCEEEEEEC
PAEPARRLVDATYEAMMAGVAAVRPGATLGDVGHAIQSVAHREGFSVVREYCGHGIGRIY
CCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
HDEPQVLHYGRPGTGLRLAPGMIFTIEPMLNAGRAETRQLADGWTVVTQDRSWSAQWEHM
CCCCCEEEECCCCCCCEECCCEEEEEECHHCCCCHHHHHHCCCCEEEEECCCCCCCCEEE
VVVTEDGFDILTPWPDAAPERSPVTARAAGAPERG
EEEEECCCEEECCCCCCCCCCCCCEEECCCCCCCC
>Mature Secondary Structure 
ARSRHVPIRTQAEIAMARRAGTMAARVLGMIAPHVKAGVTTNELDRLCREYIVDILRAR
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHCC
PANIGYHGYPKTICASVNHVVCHGIPSDHALKDGDIINIDVALDSDGWYGDTSRMYFVGE
CCCCCCCCCCHHHHHCCCEEEEECCCCCCCCCCCCEEEEEEEECCCCCCCCCCEEEEEEC
PAEPARRLVDATYEAMMAGVAAVRPGATLGDVGHAIQSVAHREGFSVVREYCGHGIGRIY
CCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
HDEPQVLHYGRPGTGLRLAPGMIFTIEPMLNAGRAETRQLADGWTVVTQDRSWSAQWEHM
CCCCCEEEECCCCCCCEECCCEEEEEECHHCCCCHHHHHHCCCCEEEEECCCCCCCCEEE
VVVTEDGFDILTPWPDAAPERSPVTARAAGAPERG
EEEEECCCEEECCCCCCCCCCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]