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The map label for this gene is cysNC [H]

Identifier: 83719339

GI number: 83719339

Start: 2204299

End: 2205792

Strand: Direct

Name: cysNC [H]

Synonym: BTH_I1952

Alternate gene names: 83719339

Gene position: 2204299-2205792 (Clockwise)

Preceding gene: 83718407

Following gene: 83720368

Centisome position: 57.87

GC content: 70.21

Gene sequence:

>1494_bases
ATGACGACGTCCATGAGAGAGCGTAGACGCGGTATTGCTTTTATGCGGTCCTGCCATGATTTTCTGCGGACATCGGAATT
GTCCGTCGCGGCAGTAAACAGCCTGCGGCGCACCATCGCGCCGTCGCATCGGGTGCTCGACCTGTGCGGATCGGGCGCGG
CCGGCCTGCTGGCGTTGCATTACGGCGCGAAGCGGGTGGTGGCGCTTGCGGCCGATGCCGCGCCGCTCGTTCGGGCCCAG
GCCGAGGCGAATGGCCTCGACAGGCGGATATCGTTCGTCGACGCCGACCGGGCCGCGATACTCGCCGCTCGGGAAGGGCG
GTTCGACGTCGTGCTGGGGCTCGCGCCCGGCGAGCGCGCGGGGCTCGATCCGCATTACGGCTTTCGGCTCGACGAATTCG
CCCGGCGGTTCGGCACGGCGAACGTCGCCGTCGTGCCCAACGGCGTGCGCTACGGCGCGCAACTCGTCGAATGGGGCGAT
GCGGCGCGGCTCGAGGCGGACGTCGCGATGAAAAAGCGCATCCTCGAATCGCGTTATGAAGTCGCGCTCGACGCGGTGCT
CGAAAAGATGGCCGATACGGCCGCGCCGCGCGGCCGCGTGCGCGCCGATGCGCTGCGCGCGCTCTGCGCGCCGCAACCGT
TTCTGACTTGCCGCCCCGGCGATTGCGGCGGAAACGGCGCGGCGGTGCCCGTGCAAGTCGAGTTGACCGCCGCGCACGGC
GGCCGCGCCGACGGCGTGGTGTGGACGCAGGAACTGATACACGACGGCATCGTCATCGAGCGAATCCAGGGATGCAGCTG
GCTCGACGAACGCGTCGATCTCGACGCGGGTGAAGCGATCGCGGTGCCCGTCGCCGACATGGCGCGGGCGGTGCCGTTCG
ACGGCGGGGAAACGTCGCCGCAGCTCGCGCCCGCGATGCGCGCGTCGGGCGCGCCCGCGCCGCTCGTCTTTTGGTTGACC
GGCATCTCGGGGGCGGGCAAGACGACGATCGCGGCGTGCTTCAAGCGGCATGCGGACGCCGATGCGTGGCCCACCGTCGT
GCTCGACGGCGACACGCTGCGCGGCGGTCTGAACGCGGATCTCGGCTTCTCCGACGCGGATCGCGCGGAAAACGTGCGCC
GCATCGCCGAAGTCGCGGCGCTGATGGCCGACACGGGGCTGCTCGTCGTCGTCTCGTGCATTTCGCCCAAGCGATCGTTT
CGCGAAACGGCGCGCGGAATCGTCGGCGCCGAGCGCTTCGTCGAGGTGTTCGTCGATACGCCGCCCGAGGTCGCGGAGGC
GCGCGATCCGAAAGGGCTGTACCGGCGCGCGCGCGCGGGGTTGATCGCGTCTTTCACCGGGGTCGATTCCGGCTACGAGC
CGCCGCCGAATCCGCAATTGCGCATCGATACGACGACGCACGACGTCGAGGCCGCGACGCAGATGCTGCGCCGCTGCTAC
ATCGACGCGCGCCTGTCCGCCGAGCGCGCGGCCGCGGCCGAGGCCGTGGCGTAA

Upstream 100 bases:

>100_bases
ATTCAGAAAATCGGTCGCTTTTTTCGTAGCGCCGCAGAAGATCAAAATACGACATCCGAGGGCGCATGCGTGTTTTGCAT
GCGCGTGTCAAAACGATTAA

Downstream 100 bases:

>100_bases
CGCCGCCGCGCGGTGCCTTCTGTCGTCGACAGCGAATAGCGAGACCAACGATGAGCGTTCATGACATGACTCGTGCGAAC
GATAGCGCACCGGTTCGAGC

Product: adenylylsulfate kinase

Products: NA

Alternate protein names: Sulfate adenylyltransferase subunit 1; ATP-sulfurylase large subunit; Sulfate adenylate transferase; SAT; Adenylyl-sulfate kinase; APS kinase; ATP adenosine-5'-phosphosulfate 3'-phosphotransferase [H]

Number of amino acids: Translated: 497; Mature: 496

Protein sequence:

>497_residues
MTTSMRERRRGIAFMRSCHDFLRTSELSVAAVNSLRRTIAPSHRVLDLCGSGAAGLLALHYGAKRVVALAADAAPLVRAQ
AEANGLDRRISFVDADRAAILAAREGRFDVVLGLAPGERAGLDPHYGFRLDEFARRFGTANVAVVPNGVRYGAQLVEWGD
AARLEADVAMKKRILESRYEVALDAVLEKMADTAAPRGRVRADALRALCAPQPFLTCRPGDCGGNGAAVPVQVELTAAHG
GRADGVVWTQELIHDGIVIERIQGCSWLDERVDLDAGEAIAVPVADMARAVPFDGGETSPQLAPAMRASGAPAPLVFWLT
GISGAGKTTIAACFKRHADADAWPTVVLDGDTLRGGLNADLGFSDADRAENVRRIAEVAALMADTGLLVVVSCISPKRSF
RETARGIVGAERFVEVFVDTPPEVAEARDPKGLYRRARAGLIASFTGVDSGYEPPPNPQLRIDTTTHDVEAATQMLRRCY
IDARLSAERAAAAEAVA

Sequences:

>Translated_497_residues
MTTSMRERRRGIAFMRSCHDFLRTSELSVAAVNSLRRTIAPSHRVLDLCGSGAAGLLALHYGAKRVVALAADAAPLVRAQ
AEANGLDRRISFVDADRAAILAAREGRFDVVLGLAPGERAGLDPHYGFRLDEFARRFGTANVAVVPNGVRYGAQLVEWGD
AARLEADVAMKKRILESRYEVALDAVLEKMADTAAPRGRVRADALRALCAPQPFLTCRPGDCGGNGAAVPVQVELTAAHG
GRADGVVWTQELIHDGIVIERIQGCSWLDERVDLDAGEAIAVPVADMARAVPFDGGETSPQLAPAMRASGAPAPLVFWLT
GISGAGKTTIAACFKRHADADAWPTVVLDGDTLRGGLNADLGFSDADRAENVRRIAEVAALMADTGLLVVVSCISPKRSF
RETARGIVGAERFVEVFVDTPPEVAEARDPKGLYRRARAGLIASFTGVDSGYEPPPNPQLRIDTTTHDVEAATQMLRRCY
IDARLSAERAAAAEAVA
>Mature_496_residues
TTSMRERRRGIAFMRSCHDFLRTSELSVAAVNSLRRTIAPSHRVLDLCGSGAAGLLALHYGAKRVVALAADAAPLVRAQA
EANGLDRRISFVDADRAAILAAREGRFDVVLGLAPGERAGLDPHYGFRLDEFARRFGTANVAVVPNGVRYGAQLVEWGDA
ARLEADVAMKKRILESRYEVALDAVLEKMADTAAPRGRVRADALRALCAPQPFLTCRPGDCGGNGAAVPVQVELTAAHGG
RADGVVWTQELIHDGIVIERIQGCSWLDERVDLDAGEAIAVPVADMARAVPFDGGETSPQLAPAMRASGAPAPLVFWLTG
ISGAGKTTIAACFKRHADADAWPTVVLDGDTLRGGLNADLGFSDADRAENVRRIAEVAALMADTGLLVVVSCISPKRSFR
ETARGIVGAERFVEVFVDTPPEVAEARDPKGLYRRARAGLIASFTGVDSGYEPPPNPQLRIDTTTHDVEAATQMLRRCYI
DARLSAERAAAAEAVA

Specific function: APS kinase catalyzes the synthesis of activated sulfate [H]

COG id: COG0529

COG function: function code P; Adenylylsulfate kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the APS kinase family [H]

Homologues:

Organism=Homo sapiens, GI46094058, Length=161, Percent_Identity=52.7950310559006, Blast_Score=158, Evalue=1e-38,
Organism=Homo sapiens, GI62912492, Length=154, Percent_Identity=52.5974025974026, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI34447231, Length=154, Percent_Identity=52.5974025974026, Blast_Score=154, Evalue=2e-37,
Organism=Escherichia coli, GI1789107, Length=170, Percent_Identity=48.2352941176471, Blast_Score=167, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17542422, Length=161, Percent_Identity=48.4472049689441, Blast_Score=152, Evalue=5e-37,
Organism=Saccharomyces cerevisiae, GI6322852, Length=172, Percent_Identity=44.1860465116279, Blast_Score=152, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24667032, Length=161, Percent_Identity=48.4472049689441, Blast_Score=153, Evalue=3e-37,
Organism=Drosophila melanogaster, GI24667028, Length=161, Percent_Identity=48.4472049689441, Blast_Score=153, Evalue=3e-37,
Organism=Drosophila melanogaster, GI24667036, Length=161, Percent_Identity=48.4472049689441, Blast_Score=153, Evalue=3e-37,
Organism=Drosophila melanogaster, GI24667040, Length=161, Percent_Identity=48.4472049689441, Blast_Score=153, Evalue=3e-37,
Organism=Drosophila melanogaster, GI116007838, Length=161, Percent_Identity=48.4472049689441, Blast_Score=152, Evalue=3e-37,
Organism=Drosophila melanogaster, GI24667044, Length=161, Percent_Identity=48.4472049689441, Blast_Score=152, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002891
- InterPro:   IPR000795
- InterPro:   IPR011779
- InterPro:   IPR009001
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF01583 APS_kinase; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: =2.7.7.4; =2.7.1.25 [H]

Molecular weight: Translated: 52950; Mature: 52819

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSMRERRRGIAFMRSCHDFLRTSELSVAAVNSLRRTIAPSHRVLDLCGSGAAGLLALH
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHH
YGAKRVVALAADAAPLVRAQAEANGLDRRISFVDADRAAILAAREGRFDVVLGLAPGERA
HCCCEEEEEECCCHHHHHHHHHHCCCHHEEEEECCCCEEEEEECCCCEEEEEEECCCCCC
GLDPHYGFRLDEFARRFGTANVAVVPNGVRYGAQLVEWGDAARLEADVAMKKRILESRYE
CCCCCCCCCHHHHHHHHCCCCEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
VALDAVLEKMADTAAPRGRVRADALRALCAPQPFLTCRPGDCGGNGAAVPVQVELTAAHG
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCCCEEEEEEEEEECCC
GRADGVVWTQELIHDGIVIERIQGCSWLDERVDLDAGEAIAVPVADMARAVPFDGGETSP
CCCCCCHHHHHHHHCCHHHHHHCCCCHHHHHCCCCCCCEEEEEHHHHHHHCCCCCCCCCC
QLAPAMRASGAPAPLVFWLTGISGAGKTTIAACFKRHADADAWPTVVLDGDTLRGGLNAD
CHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCC
LGFSDADRAENVRRIAEVAALMADTGLLVVVSCISPKRSFRETARGIVGAERFVEVFVDT
CCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCC
PPEVAEARDPKGLYRRARAGLIASFTGVDSGYEPPPNPQLRIDTTTHDVEAATQMLRRCY
CHHHHHCCCCHHHHHHHHCCCEEEECCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHH
IDARLSAERAAAAEAVA
HHHHCCHHHHHHHHHCC
>Mature Secondary Structure 
TTSMRERRRGIAFMRSCHDFLRTSELSVAAVNSLRRTIAPSHRVLDLCGSGAAGLLALH
CCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHH
YGAKRVVALAADAAPLVRAQAEANGLDRRISFVDADRAAILAAREGRFDVVLGLAPGERA
HCCCEEEEEECCCHHHHHHHHHHCCCHHEEEEECCCCEEEEEECCCCEEEEEEECCCCCC
GLDPHYGFRLDEFARRFGTANVAVVPNGVRYGAQLVEWGDAARLEADVAMKKRILESRYE
CCCCCCCCCHHHHHHHHCCCCEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
VALDAVLEKMADTAAPRGRVRADALRALCAPQPFLTCRPGDCGGNGAAVPVQVELTAAHG
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCCCEEEEEEEEEECCC
GRADGVVWTQELIHDGIVIERIQGCSWLDERVDLDAGEAIAVPVADMARAVPFDGGETSP
CCCCCCHHHHHHHHCCHHHHHHCCCCHHHHHCCCCCCCEEEEEHHHHHHHCCCCCCCCCC
QLAPAMRASGAPAPLVFWLTGISGAGKTTIAACFKRHADADAWPTVVLDGDTLRGGLNAD
CHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCC
LGFSDADRAENVRRIAEVAALMADTGLLVVVSCISPKRSFRETARGIVGAERFVEVFVDT
CCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCC
PPEVAEARDPKGLYRRARAGLIASFTGVDSGYEPPPNPQLRIDTTTHDVEAATQMLRRCY
CHHHHHCCCCHHHHHHHHCCCEEEECCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHH
IDARLSAERAAAAEAVA
HHHHCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]