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The map label for this gene is clpB [H]

Identifier: 83719137

GI number: 83719137

Start: 2480246

End: 2482843

Strand: Direct

Name: clpB [H]

Synonym: BTH_I2205

Alternate gene names: 83719137

Gene position: 2480246-2482843 (Clockwise)

Preceding gene: 83721287

Following gene: 83718632

Centisome position: 65.11

GC content: 65.86

Gene sequence:

>2598_bases
ATGAGAATCGACAAGCTCACCACCAAGTTCCAAGAAGCGCTTTCGGATGCGCAGAGTCTTGCCGCCGGGCGCGACAACCA
ATACATCGAACCCGTTCACGTGCTGGCCGCGCTGATCGCGCAGCAGGACGGCTCCGCGCGCTCGCTGCTGTCGCGCGCGG
GCGTGCACATCCAGGCGCTGCAAGGCGCGCTCAATGAAGCGATCTCGCGCTTGCCGCAGGTGACGGGCACGGGCGGCGAC
ATCCAGGTCGGCCGCGAGCTCGCGGGCCTGCTGAACCAGGCCGACAAGGAAGCGCAGAAGCTCAACGACACGTTCATCGC
GAGCGAAATGTTCCTGCTCGCCGTGGCTGACGACAAGGGTGAAGCCGGCAAGCTCGCGCGCCAGCACGGCCTCACGCGCC
GCGCGCTCGAATCCGCGATCGCCGCGGTGCGCGGCGGCTCGCAGGTGCACAGCCAGGATGCCGAGAGCCAGCGCGAGGCG
CTGAAGAAGTACACGGTCGACCTGACCGAGCGCGCGCGCGCGGGCAAGCTTGACCCCGTGATCGGCCGCGACGACGAGAT
TCGCCGTTCGATCCAGATCCTGCAGCGCCGCACGAAGAACAACCCGGTGCTGATCGGCGAGCCGGGCGTCGGCAAGACCG
CGATCGTCGAAGGGCTCGCGCAGCGCATCGTCAACGGCGAAGTGCCCGAGACGCTGAAGAACAAGCGCGTGCTGTCGCTC
GACATGGCGGCGCTGCTCGCCGGCGCGAAGTATCGCGGCGAGTTCGAGGAGCGCCTGAAGGCGGTGCTCAACGACATCGC
GAAGGATGAAGGCCGTACGATCGTCTTCATCGACGAGATTCACACGATGGTGGGCGCGGGCAAGGCCGAAGGCGCGATGG
ACGCGGGCAACATGCTCAAGCCGGCGCTCTCGCGCGGCGAGCTGCACTGCATCGGCGCGACGACGCTCGACGAATATCGC
AAGTACATCGAGAAGGACGCCGCGCTCGAGCGCCGCTTCCAGAAGGTGCTCGTCGACGAGCCGAGCGTCGAGGCGACGAT
CGCGATCCTGCGCGGGCTGCAGGAGAAGTACGAGCTGCATCACGGCGTCGAGATCACCGATCCGGCGATCGTCGCCGCGG
CGGAGCTGTCGCATCGCTACATCACCGACCGTTTCCTGCCCGACAAGGCGATCGACCTGATCGACGAGGCCGCGTCGAAG
ATCAAGATGGAAATCGATTCGAAGCCCGAAGAAATGGACAGGCTCGATCGGCGTCTGATCCAGTTGAAGATCGAGCGCGA
AGCGGTGAAGAAGGAGCAGGACGAAGCGTCGCAAAAGCGTCTCGCGCTGATCGAGGAGGAAATCGAGCGGCTCGGCCGCC
AGTACGCGGATCTCGAAGAGATCTGGACGGCGGAGAAGGCGGCCGTGCAGGGCAGCGCGCAGCTGAAGGAGGAGATCGAC
AAGGTGCGCGCCGACATCGCGCGGTTGCAGCGCGAAGGCAAGCTCGAGAAGGTCGCGGAGCTGCAGTACGGCAAGCTGCC
GCAGCTCGAGGCGCGCCTGAAGCAGGTCACGCAGGCGGAGGAAAGCGAACAGCACAATCCGACCCGGCCGCGCCTGTTGC
GCACGCAGGTCGGCGCGGAGGAAATCGCCGAGGTCGTCTCGCGTGCAACCGGCATTCCGGTGTCGCGGATGATGCAAGGC
GAGCGCGAGAAACTGCTGCACATCGAAGAGAAGCTGCATGAGCGCGTCGTTGGCCAGAACGAGGCGATCGACGCGGTTGC
CGACGCGATCCGCCGCTCGCGCGCGGGCCTCGCCGATCCGAACCGCCCGTACGGCTCGTTCCTGTTCCTCGGCCCGACGG
GCGTCGGCAAGACCGAGCTGTGCAAGGCGCTCGCCGGCTTCCTGTTCGATTCGGAAGAGCACCTGATTCGCATCGACATG
AGCGAGTTCATGGAAAAGCACAGCGTCGCGCGGCTGATCGGCGCGCCGCCCGGCTACGTCGGCTACGAGGAGGGCGGCTA
CCTGACGGAAGCCGTGCGCCGCAAGCCGTACAGCGTGATCCTGCTCGACGAGATCGAGAAGGCGCACCCGGACGTGTTCA
ACGTGCTGCTGCAGGTGCTCGACGACGGCCGGATGACGGACGGGCAGGGGCGCACCGTCGACTTCAAGAACACGGTGATC
GTGATGACGTCGAACCTCGGCTCGCAACTGATCCAGTCGATGTCGGGCTCGTCTCAGGAAGAGATCAAGGACGCGGTGTG
GGTCGAGGTCAAGCAGCACTTCCGTCCCGAGTTCCTGAACCGGATCGACGATGTCGTCGTGTTCCACTCGCTCGACCGCA
GCAACATCCAGGCGATCGCGAAGATTCAGCTCGCGCGCCTGCACGACCGGCTCGCGAAGCTCGAAATGGCGCTCGACGTG
TCCGAGGCCGCGCTCGAGCAGATCGGCAAGGTCGGCTACGATCCGCTGTTCGGCGCGCGGCCGCTCAAGCGCGCGATCCA
GCAGGAGATCGAGAACCCGGTCGCGAAGCTCATCCTCGCGGGCCGCTTCGGACCGAAGGACGTGATTCCGGTCGACGTGC
AGGACGGCAAGTTCGTGTTCGAGCGCGTCGTGCACTGA

Upstream 100 bases:

>100_bases
CGCGTGACGCGTCCCTTTGCTGTGCCTCAATAAAAAACCGGCTTGAAAGGCGGATAACCATCCTCATTTGGTTGCTATTC
GCAAATTGGAGGTCTCATTC

Downstream 100 bases:

>100_bases
TTGCCGCGTCGCGGCACGGCTCGGCGGTTCGGCGCCCGGCTTGCGGCTCGGGCGCGCCGGTGAAAGCAAAACACCCCGCG
AGAGCGGGGTGTTTTTTTGG

Product: ATP-dependent Clp protease, ATP-binding subunit ClpB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 865; Mature: 865

Protein sequence:

>865_residues
MRIDKLTTKFQEALSDAQSLAAGRDNQYIEPVHVLAALIAQQDGSARSLLSRAGVHIQALQGALNEAISRLPQVTGTGGD
IQVGRELAGLLNQADKEAQKLNDTFIASEMFLLAVADDKGEAGKLARQHGLTRRALESAIAAVRGGSQVHSQDAESQREA
LKKYTVDLTERARAGKLDPVIGRDDEIRRSIQILQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPETLKNKRVLSL
DMAALLAGAKYRGEFEERLKAVLNDIAKDEGRTIVFIDEIHTMVGAGKAEGAMDAGNMLKPALSRGELHCIGATTLDEYR
KYIEKDAALERRFQKVLVDEPSVEATIAILRGLQEKYELHHGVEITDPAIVAAAELSHRYITDRFLPDKAIDLIDEAASK
IKMEIDSKPEEMDRLDRRLIQLKIEREAVKKEQDEASQKRLALIEEEIERLGRQYADLEEIWTAEKAAVQGSAQLKEEID
KVRADIARLQREGKLEKVAELQYGKLPQLEARLKQVTQAEESEQHNPTRPRLLRTQVGAEEIAEVVSRATGIPVSRMMQG
EREKLLHIEEKLHERVVGQNEAIDAVADAIRRSRAGLADPNRPYGSFLFLGPTGVGKTELCKALAGFLFDSEEHLIRIDM
SEFMEKHSVARLIGAPPGYVGYEEGGYLTEAVRRKPYSVILLDEIEKAHPDVFNVLLQVLDDGRMTDGQGRTVDFKNTVI
VMTSNLGSQLIQSMSGSSQEEIKDAVWVEVKQHFRPEFLNRIDDVVVFHSLDRSNIQAIAKIQLARLHDRLAKLEMALDV
SEAALEQIGKVGYDPLFGARPLKRAIQQEIENPVAKLILAGRFGPKDVIPVDVQDGKFVFERVVH

Sequences:

>Translated_865_residues
MRIDKLTTKFQEALSDAQSLAAGRDNQYIEPVHVLAALIAQQDGSARSLLSRAGVHIQALQGALNEAISRLPQVTGTGGD
IQVGRELAGLLNQADKEAQKLNDTFIASEMFLLAVADDKGEAGKLARQHGLTRRALESAIAAVRGGSQVHSQDAESQREA
LKKYTVDLTERARAGKLDPVIGRDDEIRRSIQILQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPETLKNKRVLSL
DMAALLAGAKYRGEFEERLKAVLNDIAKDEGRTIVFIDEIHTMVGAGKAEGAMDAGNMLKPALSRGELHCIGATTLDEYR
KYIEKDAALERRFQKVLVDEPSVEATIAILRGLQEKYELHHGVEITDPAIVAAAELSHRYITDRFLPDKAIDLIDEAASK
IKMEIDSKPEEMDRLDRRLIQLKIEREAVKKEQDEASQKRLALIEEEIERLGRQYADLEEIWTAEKAAVQGSAQLKEEID
KVRADIARLQREGKLEKVAELQYGKLPQLEARLKQVTQAEESEQHNPTRPRLLRTQVGAEEIAEVVSRATGIPVSRMMQG
EREKLLHIEEKLHERVVGQNEAIDAVADAIRRSRAGLADPNRPYGSFLFLGPTGVGKTELCKALAGFLFDSEEHLIRIDM
SEFMEKHSVARLIGAPPGYVGYEEGGYLTEAVRRKPYSVILLDEIEKAHPDVFNVLLQVLDDGRMTDGQGRTVDFKNTVI
VMTSNLGSQLIQSMSGSSQEEIKDAVWVEVKQHFRPEFLNRIDDVVVFHSLDRSNIQAIAKIQLARLHDRLAKLEMALDV
SEAALEQIGKVGYDPLFGARPLKRAIQQEIENPVAKLILAGRFGPKDVIPVDVQDGKFVFERVVH
>Mature_865_residues
MRIDKLTTKFQEALSDAQSLAAGRDNQYIEPVHVLAALIAQQDGSARSLLSRAGVHIQALQGALNEAISRLPQVTGTGGD
IQVGRELAGLLNQADKEAQKLNDTFIASEMFLLAVADDKGEAGKLARQHGLTRRALESAIAAVRGGSQVHSQDAESQREA
LKKYTVDLTERARAGKLDPVIGRDDEIRRSIQILQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPETLKNKRVLSL
DMAALLAGAKYRGEFEERLKAVLNDIAKDEGRTIVFIDEIHTMVGAGKAEGAMDAGNMLKPALSRGELHCIGATTLDEYR
KYIEKDAALERRFQKVLVDEPSVEATIAILRGLQEKYELHHGVEITDPAIVAAAELSHRYITDRFLPDKAIDLIDEAASK
IKMEIDSKPEEMDRLDRRLIQLKIEREAVKKEQDEASQKRLALIEEEIERLGRQYADLEEIWTAEKAAVQGSAQLKEEID
KVRADIARLQREGKLEKVAELQYGKLPQLEARLKQVTQAEESEQHNPTRPRLLRTQVGAEEIAEVVSRATGIPVSRMMQG
EREKLLHIEEKLHERVVGQNEAIDAVADAIRRSRAGLADPNRPYGSFLFLGPTGVGKTELCKALAGFLFDSEEHLIRIDM
SEFMEKHSVARLIGAPPGYVGYEEGGYLTEAVRRKPYSVILLDEIEKAHPDVFNVLLQVLDDGRMTDGQGRTVDFKNTVI
VMTSNLGSQLIQSMSGSSQEEIKDAVWVEVKQHFRPEFLNRIDDVVVFHSLDRSNIQAIAKIQLARLHDRLAKLEMALDV
SEAALEQIGKVGYDPLFGARPLKRAIQQEIENPVAKLILAGRFGPKDVIPVDVQDGKFVFERVVH

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=298, Percent_Identity=36.9127516778523, Blast_Score=196, Evalue=9e-50,
Organism=Escherichia coli, GI1788943, Length=860, Percent_Identity=66.5116279069767, Blast_Score=1167, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=418, Percent_Identity=40.4306220095694, Blast_Score=286, Evalue=3e-78,
Organism=Saccharomyces cerevisiae, GI6320464, Length=712, Percent_Identity=52.3876404494382, Blast_Score=753, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=865, Percent_Identity=42.8901734104046, Blast_Score=694, Evalue=0.0,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 96051; Mature: 96051

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIDKLTTKFQEALSDAQSLAAGRDNQYIEPVHVLAALIAQQDGSARSLLSRAGVHIQAL
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCHHHHH
QGALNEAISRLPQVTGTGGDIQVGRELAGLLNQADKEAQKLNDTFIASEMFLLAVADDKG
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCC
EAGKLARQHGLTRRALESAIAAVRGGSQVHSQDAESQREALKKYTVDLTERARAGKLDPV
CHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
IGRDDEIRRSIQILQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPETLKNKRVLSL
CCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHCCCCHHH
DMAALLAGAKYRGEFEERLKAVLNDIAKDEGRTIVFIDEIHTMVGAGKAEGAMDAGNMLK
HHHHHHHCCHHCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCCCHHHH
PALSRGELHCIGATTLDEYRKYIEKDAALERRFQKVLVDEPSVEATIAILRGLQEKYELH
HHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
HGVEITDPAIVAAAELSHRYITDRFLPDKAIDLIDEAASKIKMEIDSKPEEMDRLDRRLI
CCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEHHCCCCHHHHHHHHHHHH
QLKIEREAVKKEQDEASQKRLALIEEEIERLGRQYADLEEIWTAEKAAVQGSAQLKEEID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
KVRADIARLQREGKLEKVAELQYGKLPQLEARLKQVTQAEESEQHNPTRPRLLRTQVGAE
HHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHH
EIAEVVSRATGIPVSRMMQGEREKLLHIEEKLHERVVGQNEAIDAVADAIRRSRAGLADP
HHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCC
NRPYGSFLFLGPTGVGKTELCKALAGFLFDSEEHLIRIDMSEFMEKHSVARLIGAPPGYV
CCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCC
GYEEGGYLTEAVRRKPYSVILLDEIEKAHPDVFNVLLQVLDDGRMTDGQGRTVDFKNTVI
CCCCCCHHHHHHHCCCCEEEEEHHHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEECCEEE
VMTSNLGSQLIQSMSGSSQEEIKDAVWVEVKQHFRPEFLNRIDDVVVFHSLDRSNIQAIA
EEECCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHH
KIQLARLHDRLAKLEMALDVSEAALEQIGKVGYDPLFGARPLKRAIQQEIENPVAKLILA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
GRFGPKDVIPVDVQDGKFVFERVVH
CCCCCCCCEEECCCCCHHHHHHHCC
>Mature Secondary Structure
MRIDKLTTKFQEALSDAQSLAAGRDNQYIEPVHVLAALIAQQDGSARSLLSRAGVHIQAL
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCHHHHH
QGALNEAISRLPQVTGTGGDIQVGRELAGLLNQADKEAQKLNDTFIASEMFLLAVADDKG
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCC
EAGKLARQHGLTRRALESAIAAVRGGSQVHSQDAESQREALKKYTVDLTERARAGKLDPV
CHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
IGRDDEIRRSIQILQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPETLKNKRVLSL
CCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHCCCCHHH
DMAALLAGAKYRGEFEERLKAVLNDIAKDEGRTIVFIDEIHTMVGAGKAEGAMDAGNMLK
HHHHHHHCCHHCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCCCHHHH
PALSRGELHCIGATTLDEYRKYIEKDAALERRFQKVLVDEPSVEATIAILRGLQEKYELH
HHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
HGVEITDPAIVAAAELSHRYITDRFLPDKAIDLIDEAASKIKMEIDSKPEEMDRLDRRLI
CCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEHHCCCCHHHHHHHHHHHH
QLKIEREAVKKEQDEASQKRLALIEEEIERLGRQYADLEEIWTAEKAAVQGSAQLKEEID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
KVRADIARLQREGKLEKVAELQYGKLPQLEARLKQVTQAEESEQHNPTRPRLLRTQVGAE
HHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHH
EIAEVVSRATGIPVSRMMQGEREKLLHIEEKLHERVVGQNEAIDAVADAIRRSRAGLADP
HHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCC
NRPYGSFLFLGPTGVGKTELCKALAGFLFDSEEHLIRIDMSEFMEKHSVARLIGAPPGYV
CCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCC
GYEEGGYLTEAVRRKPYSVILLDEIEKAHPDVFNVLLQVLDDGRMTDGQGRTVDFKNTVI
CCCCCCHHHHHHHCCCCEEEEEHHHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEECCEEE
VMTSNLGSQLIQSMSGSSQEEIKDAVWVEVKQHFRPEFLNRIDDVVVFHSLDRSNIQAIA
EEECCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHH
KIQLARLHDRLAKLEMALDVSEAALEQIGKVGYDPLFGARPLKRAIQQEIENPVAKLILA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
GRFGPKDVIPVDVQDGKFVFERVVH
CCCCCCCCEEECCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]