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The map label for this gene is upp [H]

Identifier: 83719080

GI number: 83719080

Start: 1152933

End: 1153583

Strand: Reverse

Name: upp [H]

Synonym: BTH_I1016

Alternate gene names: 83719080

Gene position: 1153583-1152933 (Counterclockwise)

Preceding gene: 83719081

Following gene: 83721410

Centisome position: 30.28

GC content: 66.67

Gene sequence:

>651_bases
ATGAAACAGGACAGCCGTTTTCCGAATCTCTTCATCCTCGACCATCCGCTGATCCAGCACAAACTCACGCACATGCGCGA
CAAGGACACGTCCACGCGTACGTTCCGCGAACTGCTGCGCGAGATCACGCTGCTGATGGGCTACGAGATCACCCGCAACC
TGCCGATCACGACGAAGCGGGTCGAAACCCCGCTCGTCGAGATCGACGCGCCCGTGATCGCCGGCAAGAAGCTCGCGATC
GTGCCCGTGCTGCGCGCGGGCGTCGGCATGTCGGACGGGCTGCTCGAGCTGATTCCGTCGGCGCGCGTCGGCCACATCGG
CGTGTACCGCGCCGACGACCACCGCCCGGTCGAATACCTGGTGCGGCTGCCCGACCTCGAAGACCGGATCTTCATCCTGT
GCGACCCGATGGTCGCGACGGGCTACTCGGCCGCGCATGCGATCGACGTGCTCAAGCGCCGAGGCGTGCCGGGCGAGCGG
ATCATGTTCCTCGCGCTCGTCGCCGCGCCCGAAGGCGTGCAGGTGTTCCAGGACGCGCACCCGGACGTGAAGCTCTATGT
GGCGTCGCTCGACTCGCACCTCGACGACCACGCGTACATCGTCCCGGGCCTGGGCGACGCGGGCGACCGCCTGTTCGGCA
CGAAGAACTGA

Upstream 100 bases:

>100_bases
GATCGCGCGCGCCCATCTTCGGTAAACTTGCGGCTGTCGCGCGCGCGGCGTGCCGCCCCGGCACGCCCGCCGTCCCAGAA
TCCTTTGAGCCGCCGCTTCC

Downstream 100 bases:

>100_bases
CCGCCCCCGCGAGCGAAACCGGCGACCGCAGCCGGCGCATGGCGCGCCCCGCCGCGCTCGCGCGCGGCTCGCCCCGGCAC
GCGAACGATTCGCGGACGAT

Product: uracil phosphoribosyltransferase

Products: NA

Alternate protein names: UMP pyrophosphorylase; UPRTase [H]

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MKQDSRFPNLFILDHPLIQHKLTHMRDKDTSTRTFRELLREITLLMGYEITRNLPITTKRVETPLVEIDAPVIAGKKLAI
VPVLRAGVGMSDGLLELIPSARVGHIGVYRADDHRPVEYLVRLPDLEDRIFILCDPMVATGYSAAHAIDVLKRRGVPGER
IMFLALVAAPEGVQVFQDAHPDVKLYVASLDSHLDDHAYIVPGLGDAGDRLFGTKN

Sequences:

>Translated_216_residues
MKQDSRFPNLFILDHPLIQHKLTHMRDKDTSTRTFRELLREITLLMGYEITRNLPITTKRVETPLVEIDAPVIAGKKLAI
VPVLRAGVGMSDGLLELIPSARVGHIGVYRADDHRPVEYLVRLPDLEDRIFILCDPMVATGYSAAHAIDVLKRRGVPGER
IMFLALVAAPEGVQVFQDAHPDVKLYVASLDSHLDDHAYIVPGLGDAGDRLFGTKN
>Mature_216_residues
MKQDSRFPNLFILDHPLIQHKLTHMRDKDTSTRTFRELLREITLLMGYEITRNLPITTKRVETPLVEIDAPVIAGKKLAI
VPVLRAGVGMSDGLLELIPSARVGHIGVYRADDHRPVEYLVRLPDLEDRIFILCDPMVATGYSAAHAIDVLKRRGVPGER
IMFLALVAAPEGVQVFQDAHPDVKLYVASLDSHLDDHAYIVPGLGDAGDRLFGTKN

Specific function: Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate [H]

COG id: COG0035

COG function: function code F; Uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPRTase family [H]

Homologues:

Organism=Homo sapiens, GI301129207, Length=202, Percent_Identity=33.1683168316832, Blast_Score=88, Evalue=6e-18,
Organism=Homo sapiens, GI57863312, Length=202, Percent_Identity=33.1683168316832, Blast_Score=88, Evalue=7e-18,
Organism=Escherichia coli, GI87082118, Length=208, Percent_Identity=49.0384615384615, Blast_Score=194, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI17539892, Length=209, Percent_Identity=27.2727272727273, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17539894, Length=209, Percent_Identity=27.2727272727273, Blast_Score=77, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6321920, Length=211, Percent_Identity=36.9668246445498, Blast_Score=119, Evalue=4e-28,
Organism=Drosophila melanogaster, GI45550449, Length=222, Percent_Identity=33.3333333333333, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI28573516, Length=222, Percent_Identity=33.3333333333333, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI28573514, Length=222, Percent_Identity=33.3333333333333, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI28573512, Length=222, Percent_Identity=33.3333333333333, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI21358379, Length=209, Percent_Identity=28.2296650717703, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: 2580 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005765 [H]

Pfam domain/function: NA

EC number: =2.4.2.9 [H]

Molecular weight: Translated: 24075; Mature: 24075

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQDSRFPNLFILDHPLIQHKLTHMRDKDTSTRTFRELLREITLLMGYEITRNLPITTKR
CCCCCCCCEEEEECCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCHHHHCCCCCCHHH
VETPLVEIDAPVIAGKKLAIVPVLRAGVGMSDGLLELIPSARVGHIGVYRADDHRPVEYL
CCCCEEEECCCEECCCCEEEEEHHHHCCCCCCCHHHHCCCCCCCEEEEEECCCCCCHHHE
VRLPDLEDRIFILCDPMVATGYSAAHAIDVLKRRGVPGERIMFLALVAAPEGVQVFQDAH
EECCCCCCCEEEEECCHHHCCCHHHHHHHHHHHCCCCCHHEEEEEEECCCCCHHHHHCCC
PDVKLYVASLDSHLDDHAYIVPGLGDAGDRLFGTKN
CCEEEEEEEHHCCCCCCEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MKQDSRFPNLFILDHPLIQHKLTHMRDKDTSTRTFRELLREITLLMGYEITRNLPITTKR
CCCCCCCCEEEEECCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCHHHHCCCCCCHHH
VETPLVEIDAPVIAGKKLAIVPVLRAGVGMSDGLLELIPSARVGHIGVYRADDHRPVEYL
CCCCEEEECCCEECCCCEEEEEHHHHCCCCCCCHHHHCCCCCCCEEEEEECCCCCCHHHE
VRLPDLEDRIFILCDPMVATGYSAAHAIDVLKRRGVPGERIMFLALVAAPEGVQVFQDAH
EECCCCCCCEEEEECCHHHCCCHHHHHHHHHHHCCCCCHHEEEEEEECCCCCHHHHHCCC
PDVKLYVASLDSHLDDHAYIVPGLGDAGDRLFGTKN
CCEEEEEEEHHCCCCCCEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA