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The map label for this gene is rppH [H]

Identifier: 83719033

GI number: 83719033

Start: 1290605

End: 1291255

Strand: Reverse

Name: rppH [H]

Synonym: BTH_I1145

Alternate gene names: 83719033

Gene position: 1291255-1290605 (Counterclockwise)

Preceding gene: 83719079

Following gene: 83718686

Centisome position: 33.9

GC content: 64.06

Gene sequence:

>651_bases
ATGCTGGATCGTGAAGGCTTTCGCCCGAACGTCGGCATCATCCTCTTGAACGCGCACAACGAGGTGTTTTGGGGCAAGCG
GCTCCGCGAGCATTCCTGGCAGTTTCCGCAAGGGGGCATCAAGTACGGCGAGACCCCGATGCAGGCGATGTACAGGGAAC
TGCACGAGGAAACCGGGCTGCTGCCGGAACACGTCAAGATCATCGGCCGCACTCGCGACTGGTTGCGTTATGAGGTGCCA
GACAAGTTCATCAAGCGCGAAGTGCGCGGCCATTATCGCGGCCAGAAGCAGATCTGGTTCCTGCTGCGCATGGTCGGCCG
CGATTGCGACATCTGCCTGCGGGCGACGGACCATCCGGAGTTCGACGCGTGGCGCTGGAACGAATACTGGGTGCCACTCG
ACGCGGTGATCGAGTTCAAGCGGGATGTGTATCAGTTGGCGTTGACCGAACTGTCGCGTTTCCTGCGCCGCCCGGCGCAG
CGCACCGACAAGTCGCGCGGTCCGCGCGCGCCGCGCTATCCGCGCGTCTCGAACGGGCACGCGGCATCGGAGACACCGGC
CGTGATCGATGCGTCGGCGGTCTGTTCGGAAGTCGAGCCGGGCGCGAGCACGCTCGACGAAATCCCTCCCCGCCTGATTC
TGCGCGACTGA

Upstream 100 bases:

>100_bases
TGTAGTTGACGCGCCCCGCCCGGATTCGCTCCGTTCCGGTGCGCAACGCCCGTTATCTGTTTATAATCAAAGCAATTTTA
AAGGATTCGAAGGTGGTTGT

Downstream 100 bases:

>100_bases
CGCGCAGGCACGTTCGACGGGAATGAAAACGCATGACCGGGCGCGGCATTGAAGGATGCCGCGCCTTTTTTACGAGGCAC
CCATATTGAAAGCGATTGCT

Product: dinucleoside polyphosphate hydrolase

Products: NA

Alternate protein names: (Di)nucleoside polyphosphate hydrolase [H]

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MLDREGFRPNVGIILLNAHNEVFWGKRLREHSWQFPQGGIKYGETPMQAMYRELHEETGLLPEHVKIIGRTRDWLRYEVP
DKFIKREVRGHYRGQKQIWFLLRMVGRDCDICLRATDHPEFDAWRWNEYWVPLDAVIEFKRDVYQLALTELSRFLRRPAQ
RTDKSRGPRAPRYPRVSNGHAASETPAVIDASAVCSEVEPGASTLDEIPPRLILRD

Sequences:

>Translated_216_residues
MLDREGFRPNVGIILLNAHNEVFWGKRLREHSWQFPQGGIKYGETPMQAMYRELHEETGLLPEHVKIIGRTRDWLRYEVP
DKFIKREVRGHYRGQKQIWFLLRMVGRDCDICLRATDHPEFDAWRWNEYWVPLDAVIEFKRDVYQLALTELSRFLRRPAQ
RTDKSRGPRAPRYPRVSNGHAASETPAVIDASAVCSEVEPGASTLDEIPPRLILRD
>Mature_216_residues
MLDREGFRPNVGIILLNAHNEVFWGKRLREHSWQFPQGGIKYGETPMQAMYRELHEETGLLPEHVKIIGRTRDWLRYEVP
DKFIKREVRGHYRGQKQIWFLLRMVGRDCDICLRATDHPEFDAWRWNEYWVPLDAVIEFKRDVYQLALTELSRFLRRPAQ
RTDKSRGPRAPRYPRVSNGHAASETPAVIDASAVCSEVEPGASTLDEIPPRLILRD

Specific function: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1789194, Length=175, Percent_Identity=45.1428571428571, Blast_Score=173, Evalue=8e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR022927 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 25362; Mature: 25362

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDREGFRPNVGIILLNAHNEVFWGKRLREHSWQFPQGGIKYGETPMQAMYRELHEETGL
CCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
LPEHVKIIGRTRDWLRYEVPDKFIKREVRGHYRGQKQIWFLLRMVGRDCDICLRATDHPE
CHHHHHHHHCCHHHHEECCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEECCCCCC
FDAWRWNEYWVPLDAVIEFKRDVYQLALTELSRFLRRPAQRTDKSRGPRAPRYPRVSNGH
CCCEECCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
AASETPAVIDASAVCSEVEPGASTLDEIPPRLILRD
CCCCCCCCEEHHHHHHCCCCCHHHHHHCCCCEECCC
>Mature Secondary Structure
MLDREGFRPNVGIILLNAHNEVFWGKRLREHSWQFPQGGIKYGETPMQAMYRELHEETGL
CCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
LPEHVKIIGRTRDWLRYEVPDKFIKREVRGHYRGQKQIWFLLRMVGRDCDICLRATDHPE
CHHHHHHHHCCHHHHEECCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEECCCCCC
FDAWRWNEYWVPLDAVIEFKRDVYQLALTELSRFLRRPAQRTDKSRGPRAPRYPRVSNGH
CCCEECCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
AASETPAVIDASAVCSEVEPGASTLDEIPPRLILRD
CCCCCCCCEEHHHHHHCCCCCHHHHHHCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA