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The map label for this gene is nahR [H]

Identifier: 83718883

GI number: 83718883

Start: 2348755

End: 2350278

Strand: Reverse

Name: nahR [H]

Synonym: BTH_I2074

Alternate gene names: 83718883

Gene position: 2350278-2348755 (Counterclockwise)

Preceding gene: 83720005

Following gene: 83720027

Centisome position: 61.7

GC content: 64.57

Gene sequence:

>1524_bases
ATGCGTCCCGCCGCACGTCGCGCGTATCGGGCGAACGGTCGTCCTGCCCGCACGACGATTTGCGGCGAACCGCGCGACGT
CGCTCGTTCACCGCGTTCCGCACGGCCGGGCCGCTTGCCGAAATCGATGCGGAATCGGCGACGCCCTCGCGCGCGACGCA
CAACGACAACATTGCGCCGACGCGCATCGACACGCGTGACGCCCCGGTCCGGCGCGCCGATGTGCGCGGCCGCCGCGTTA
CCGGTTTGGCCTCCTTTGCACGTCGCCGTATCGACCTATTTTCGTCGCTCGTTTCACCCTCTTCTCTCGCCATCCATTTT
TTGCCCCCCTTCTTGCCGCCCCTTTTTCGAACTCCTTTTCGAATTCCTTTTTGCGCGCCTTTTCGCCATCCTTTTCGCGA
TCCTCATCGGCGCGCCTTTGCGCGCTTGCACCGCAAGCTCGTCACTCGCCGTCCGCGCCGCTCGCCCGTCGCGAATCGTC
CGCGCCGCGCGCGGCGACTCGAATGCGCCGCTCTTGACGCTCCTTTATGTCCATATTAAAAACCATATACCCCCACCCTC
AATCGATCAGCCCGGACATATAAACGGAGAGAGCATGAGCCAGCAACGCGAGGCGATCGACACGTATTTATTGCGCGTCC
TGCACACTTTGCTGATGGAGCGCAGCGTGACGCGCGCGGCCGTCAAGCTGAATCAGTCGCAACCGGCGATCAGCGCCGCG
CTGCGCCGTCTGCGCGACATCACGGGCGACCCGCTCCTCGTGCGCGGCAAGTCCGGCATGGTGCCGACCGAGTACGGCCT
GCGCCTGCTCGAACCCGTGCAGAACGCGCTGCGCGAAATCGAACGGATCAAGTTCCAGCAGCACAATTTCGATCCGGCGA
CATCGATCCGCTGCTACCGGATCGGCTGTCCGGATTACCTGAACGTGCTGTTCGTGCCGACCGTCGTCGAGCGCTTCCGC
CAGGCCGCGCCGAACGCGACGCTCGAATTCCATTCGCTCGGCCCCGCGTTCGACTACGAGCTCGCGCTCGAGGACGGCAA
GCTCGACATCGTCGTCGGCAACTGGCCGGAGCCGCCCGAGCAGTTGCATCTGTCGAACCTGTTCGTCGACGAGATCGTGT
GCCTGATGAGCAACGCGCATCCGTTCGCCAAGCGCGGCGGCCTCACGCTCGATCAATACCTGAACGCGCCGCATCTCGCG
CCGACGCCGTACTCGGTCGGGCAGCGCGGCGCGATCGACGTCCATCTCGCGCGCGAACGCCTGAAGCGCCACGTCGTCGT
CACGCTGCCGTACTTCAATCTCGCACCTTACGTGCTCGTGAAGTCGGATCTGATCTTCACGACGACGCGGCTCTTCGCCG
ATCACTACGCGAAGTTCCTGCCGCTGTCCGTCGTGCCCGCGCCGCTCGATTTTCCGCCGATGCAGTACTACCAGCTCTGG
CACGAACGCTGCCATTACTCGGACGAGGTGCGCTGGCTGCGCGGGCTCGTCGCCGAAGCGACGCGCACGCTGATCGATGC
GTAA

Upstream 100 bases:

>100_bases
GAACGCTCGTTCGCGCGGGAAGCGACAGTCGCACCGCGACACACGCGTAACGCATGCCGGATCTTGCCGCTGCCGCGCTG
CGGCATTCGACGAAATCGAC

Downstream 100 bases:

>100_bases
GGGCGCGAGGCGCGGAATGCGCGGAGACTGATGCGCGTGTCAGCGGTGTCGGCGGTGTCCGCAACACCATCGATCGACGT
CCATTCCGCTACAGCCATCG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 507; Mature: 507

Protein sequence:

>507_residues
MRPAARRAYRANGRPARTTICGEPRDVARSPRSARPGRLPKSMRNRRRPRARRTTTTLRRRASTRVTPRSGAPMCAAAAL
PVWPPLHVAVSTYFRRSFHPLLSPSIFCPPSCRPFFELLFEFLFARLFAILFAILIGAPLRACTASSSLAVRAARPSRIV
RAARGDSNAPLLTLLYVHIKNHIPPPSIDQPGHINGESMSQQREAIDTYLLRVLHTLLMERSVTRAAVKLNQSQPAISAA
LRRLRDITGDPLLVRGKSGMVPTEYGLRLLEPVQNALREIERIKFQQHNFDPATSIRCYRIGCPDYLNVLFVPTVVERFR
QAAPNATLEFHSLGPAFDYELALEDGKLDIVVGNWPEPPEQLHLSNLFVDEIVCLMSNAHPFAKRGGLTLDQYLNAPHLA
PTPYSVGQRGAIDVHLARERLKRHVVVTLPYFNLAPYVLVKSDLIFTTTRLFADHYAKFLPLSVVPAPLDFPPMQYYQLW
HERCHYSDEVRWLRGLVAEATRTLIDA

Sequences:

>Translated_507_residues
MRPAARRAYRANGRPARTTICGEPRDVARSPRSARPGRLPKSMRNRRRPRARRTTTTLRRRASTRVTPRSGAPMCAAAAL
PVWPPLHVAVSTYFRRSFHPLLSPSIFCPPSCRPFFELLFEFLFARLFAILFAILIGAPLRACTASSSLAVRAARPSRIV
RAARGDSNAPLLTLLYVHIKNHIPPPSIDQPGHINGESMSQQREAIDTYLLRVLHTLLMERSVTRAAVKLNQSQPAISAA
LRRLRDITGDPLLVRGKSGMVPTEYGLRLLEPVQNALREIERIKFQQHNFDPATSIRCYRIGCPDYLNVLFVPTVVERFR
QAAPNATLEFHSLGPAFDYELALEDGKLDIVVGNWPEPPEQLHLSNLFVDEIVCLMSNAHPFAKRGGLTLDQYLNAPHLA
PTPYSVGQRGAIDVHLARERLKRHVVVTLPYFNLAPYVLVKSDLIFTTTRLFADHYAKFLPLSVVPAPLDFPPMQYYQLW
HERCHYSDEVRWLRGLVAEATRTLIDA
>Mature_507_residues
MRPAARRAYRANGRPARTTICGEPRDVARSPRSARPGRLPKSMRNRRRPRARRTTTTLRRRASTRVTPRSGAPMCAAAAL
PVWPPLHVAVSTYFRRSFHPLLSPSIFCPPSCRPFFELLFEFLFARLFAILFAILIGAPLRACTASSSLAVRAARPSRIV
RAARGDSNAPLLTLLYVHIKNHIPPPSIDQPGHINGESMSQQREAIDTYLLRVLHTLLMERSVTRAAVKLNQSQPAISAA
LRRLRDITGDPLLVRGKSGMVPTEYGLRLLEPVQNALREIERIKFQQHNFDPATSIRCYRIGCPDYLNVLFVPTVVERFR
QAAPNATLEFHSLGPAFDYELALEDGKLDIVVGNWPEPPEQLHLSNLFVDEIVCLMSNAHPFAKRGGLTLDQYLNAPHLA
PTPYSVGQRGAIDVHLARERLKRHVVVTLPYFNLAPYVLVKSDLIFTTTRLFADHYAKFLPLSVVPAPLDFPPMQYYQLW
HERCHYSDEVRWLRGLVAEATRTLIDA

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=320, Percent_Identity=26.5625, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1790147, Length=298, Percent_Identity=23.8255033557047, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788481, Length=225, Percent_Identity=30.2222222222222, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 57211; Mature: 57211

Theoretical pI: Translated: 10.70; Mature: 10.70

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPAARRAYRANGRPARTTICGEPRDVARSPRSARPGRLPKSMRNRRRPRARRTTTTLRR
CCCHHHHHHHCCCCCCCCEECCCCHHHHCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHH
RASTRVTPRSGAPMCAAAALPVWPPLHVAVSTYFRRSFHPLLSPSIFCPPSCRPFFELLF
HHHCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHH
EFLFARLFAILFAILIGAPLRACTASSSLAVRAARPSRIVRAARGDSNAPLLTLLYVHIK
HHHHHHHHHHHHHHHHCCCHHHHHCCCCEEEEECCHHHHHHHHCCCCCCCHHHHHHHHHH
NHIPPPSIDQPGHINGESMSQQREAIDTYLLRVLHTLLMERSVTRAAVKLNQSQPAISAA
HCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LRRLRDITGDPLLVRGKSGMVPTEYGLRLLEPVQNALREIERIKFQQHNFDPATSIRCYR
HHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
IGCPDYLNVLFVPTVVERFRQAAPNATLEFHSLGPAFDYELALEDGKLDIVVGNWPEPPE
ECCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEEECCCEEEEECCCCCCHH
QLHLSNLFVDEIVCLMSNAHPFAKRGGLTLDQYLNAPHLAPTPYSVGQRGAIDVHLARER
HHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHH
LKRHVVVTLPYFNLAPYVLVKSDLIFTTTRLFADHYAKFLPLSVVPAPLDFPPMQYYQLW
HHCCEEEEECCCCCCCHHEEECCHHHHHHHHHHHHHHHHCCHHEECCCCCCCHHHHHHHH
HERCHYSDEVRWLRGLVAEATRTLIDA
HHHCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRPAARRAYRANGRPARTTICGEPRDVARSPRSARPGRLPKSMRNRRRPRARRTTTTLRR
CCCHHHHHHHCCCCCCCCEECCCCHHHHCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHH
RASTRVTPRSGAPMCAAAALPVWPPLHVAVSTYFRRSFHPLLSPSIFCPPSCRPFFELLF
HHHCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHH
EFLFARLFAILFAILIGAPLRACTASSSLAVRAARPSRIVRAARGDSNAPLLTLLYVHIK
HHHHHHHHHHHHHHHHCCCHHHHHCCCCEEEEECCHHHHHHHHCCCCCCCHHHHHHHHHH
NHIPPPSIDQPGHINGESMSQQREAIDTYLLRVLHTLLMERSVTRAAVKLNQSQPAISAA
HCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LRRLRDITGDPLLVRGKSGMVPTEYGLRLLEPVQNALREIERIKFQQHNFDPATSIRCYR
HHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
IGCPDYLNVLFVPTVVERFRQAAPNATLEFHSLGPAFDYELALEDGKLDIVVGNWPEPPE
ECCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEEECCCEEEEECCCCCCHH
QLHLSNLFVDEIVCLMSNAHPFAKRGGLTLDQYLNAPHLAPTPYSVGQRGAIDVHLARER
HHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHH
LKRHVVVTLPYFNLAPYVLVKSDLIFTTTRLFADHYAKFLPLSVVPAPLDFPPMQYYQLW
HHCCEEEEECCCCCCCHHEEECCHHHHHHHHHHHHHHHHCCHHEECCCCCCCHHHHHHHH
HERCHYSDEVRWLRGLVAEATRTLIDA
HHHCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]