Click here to switch to the map view.

The map label for this gene is yedX [C]

Identifier: 83720027

GI number: 83720027

Start: 2346167

End: 2346751

Strand: Reverse

Name: yedX [C]

Synonym: BTH_I2072

Alternate gene names: 83720027

Gene position: 2346751-2346167 (Counterclockwise)

Preceding gene: 83718883

Following gene: 83721057

Centisome position: 61.61

GC content: 67.18

Gene sequence:

>585_bases
ATGCAACGGCCGCCGGCCCGCCCGCGCGCCGCGCATGGACGTGCGCTCATGCGGCGCGCATTATCTTCGTTATCGCTCAC
GGTTTGCCGTCCGAACCTTTTTACAATGGCTGCACGGCGCTCGCTTCGATCCGCCGACGGGTATGTAGCCACTGACGTGG
AGCCTCGATCCGCCGCAGCATCACCGGATCGAGCCGCCGCCGATCCTCGCGACAACACAAGGACATTGCGAATGGGAAAG
CTCACTACCCACGTACTCGACACCGCGCACGGCCGTCCGGGCGCCGCGATCAAGATCGAGCTCCATGCGATCTCGGGCGG
CGGCAGCCGCCTGCTGAAGACCGCGCTCACGAATGACGACGGCCGCTGCGACGCGCCGCTCCTCGAAGGCGATGCGCTCG
CGGCCGGCACCTACGAGCTCGTGTTCCACGCCGGCGACTACTTCGCCGCGCAAGGCGTCGCGCTGCCCGAGCCGCGCTTC
GTCGATCTCGTCGTGCTGCGTTTCGGCGTCGCCGATCCGGCCGCGCACTATCACGTGCCGCTTCTCGTGTCGCCGTGGTC
GTACAGCACCTATCGAGGCAGTTGA

Upstream 100 bases:

>100_bases
TGCGCGCCGCCGCGCACGCGCTTCGCTCCCCCGCATCGCCCCCCCCGCTTCGCCACCGCATTGACCGCCGCATGCGCGCC
GCCGCGCACGCACTTCGCCC

Downstream 100 bases:

>100_bases
GCGCATATCGCTGCCCGTACACGACAACGATGGACTCAGGAGGAGTTTCATGGAAGGCTTCATCATCGACTGGCTGAATC
TCGCGATCCGCTGGCTGCAT

Product: transthyretin family protein

Products: NA

Alternate protein names: HIU hydrolase; HIUHase [H]

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MQRPPARPRAAHGRALMRRALSSLSLTVCRPNLFTMAARRSLRSADGYVATDVEPRSAAASPDRAAADPRDNTRTLRMGK
LTTHVLDTAHGRPGAAIKIELHAISGGGSRLLKTALTNDDGRCDAPLLEGDALAAGTYELVFHAGDYFAAQGVALPEPRF
VDLVVLRFGVADPAAHYHVPLLVSPWSYSTYRGS

Sequences:

>Translated_194_residues
MQRPPARPRAAHGRALMRRALSSLSLTVCRPNLFTMAARRSLRSADGYVATDVEPRSAAASPDRAAADPRDNTRTLRMGK
LTTHVLDTAHGRPGAAIKIELHAISGGGSRLLKTALTNDDGRCDAPLLEGDALAAGTYELVFHAGDYFAAQGVALPEPRF
VDLVVLRFGVADPAAHYHVPLLVSPWSYSTYRGS
>Mature_194_residues
MQRPPARPRAAHGRALMRRALSSLSLTVCRPNLFTMAARRSLRSADGYVATDVEPRSAAASPDRAAADPRDNTRTLRMGK
LTTHVLDTAHGRPGAAIKIELHAISGGGSRLLKTALTNDDGRCDAPLLEGDALAAGTYELVFHAGDYFAAQGVALPEPRF
VDLVVLRFGVADPAAHYHVPLLVSPWSYSTYRGS

Specific function: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) [H]

COG id: COG2351

COG function: function code R; Transthyretin-like protein

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788281, Length=114, Percent_Identity=38.5964912280702, Blast_Score=80, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI115534555, Length=116, Percent_Identity=37.9310344827586, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI115532922, Length=114, Percent_Identity=35.9649122807018, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI115532920, Length=115, Percent_Identity=36.5217391304348, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24652571, Length=116, Percent_Identity=37.9310344827586, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014306
- InterPro:   IPR000895 [H]

Pfam domain/function: PF00576 Transthyretin [H]

EC number: =3.5.2.17 [H]

Molecular weight: Translated: 20798; Mature: 20798

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: PS00768 TRANSTHYRETIN_1 ; PS00769 TRANSTHYRETIN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRPPARPRAAHGRALMRRALSSLSLTVCRPNLFTMAARRSLRSADGYVATDVEPRSAAA
CCCCCCCCCCHHHHHHHHHHHHHCEEEEECCCHHHHHHHHHHHCCCCEEEECCCCCCCCC
SPDRAAADPRDNTRTLRMGKLTTHVLDTAHGRPGAAIKIELHAISGGGSRLLKTALTNDD
CCCCCCCCCCCCCEEEEECHHHHHHHHCCCCCCCCEEEEEEEEECCCCHHHHHHHHCCCC
GRCDAPLLEGDALAAGTYELVFHAGDYFAAQGVALPEPRFVDLVVLRFGVADPAAHYHVP
CCCCCCEECCCEECCCEEEEEEECCCCCEECCCCCCCCCHHEEEEEECCCCCCCCCEEEE
LLVSPWSYSTYRGS
EEECCCCCCCCCCC
>Mature Secondary Structure
MQRPPARPRAAHGRALMRRALSSLSLTVCRPNLFTMAARRSLRSADGYVATDVEPRSAAA
CCCCCCCCCCHHHHHHHHHHHHHCEEEEECCCHHHHHHHHHHHCCCCEEEECCCCCCCCC
SPDRAAADPRDNTRTLRMGKLTTHVLDTAHGRPGAAIKIELHAISGGGSRLLKTALTNDD
CCCCCCCCCCCCCEEEEECHHHHHHHHCCCCCCCCEEEEEEEEECCCCHHHHHHHHCCCC
GRCDAPLLEGDALAAGTYELVFHAGDYFAAQGVALPEPRFVDLVVLRFGVADPAAHYHVP
CCCCCCEECCCEECCCEEEEEEECCCCCEECCCCCCCCCHHEEEEEECCCCCCCCCEEEE
LLVSPWSYSTYRGS
EEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]