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The map label for this gene is zraR [H]

Identifier: 83718878

GI number: 83718878

Start: 166047

End: 166733

Strand: Direct

Name: zraR [H]

Synonym: BTH_I0135

Alternate gene names: 83718878

Gene position: 166047-166733 (Clockwise)

Preceding gene: 83720407

Following gene: 83719597

Centisome position: 4.36

GC content: 68.41

Gene sequence:

>687_bases
ATGGCAACCATCCTGGTGGTAGATGATGAAATGGGCATCCGGGAATTGCTCTCGGAGATCCTCAGCGACGAAGGGCACGT
CGTCGACGTCGCGGAGAACGCGCAGGCCGCGCGCGACTACCGGCTGCGGCATGCGCCCGATCTCGTGCTGCTCGACATCT
GGATGCCCGACACCGACGGCGTCACGTTGCTGAAGGAATGGGCGAGCCAGGGACAGCTGACGATGCCCGTCATCATGATG
TCGGGGCACGCGACGATCGACACGGCCGTCGAGGCGACGAAGATCGGCGCGCTCGATTTCCTCGAGAAGCCGATCACGCT
GCAGAAGCTGCTGAAGTCGGTCGAGCACGGTCTCGCGCGCGGCGCGGCGCCGCTGCCCGCGAGCGCGGCGACGAAGCCGG
CGGCGGGAGCGTCGTCGGTCGCGTCGGCGGCCGCGCTGCCGATGCTCGGCGACGATCCCGCCGCCGCGCTCGCGGGCCAG
ACGACAGCCGCGATCCCTTTCGACATTCCGCTGCGCGAGGCGCGCGACGCGTTCGAGCGCGCGTACTTCGAATATCACCT
CGCGCGCGAGAACGGCAGCATGACGCGCGTCGCGGAGAAGACGGGCCTCGAGCGCACGCACCTGTACCGGAAGCTGAAGC
AACTCGGCGTCGAGCTCGGCAAGAAGCCGGCCGAAGGCGCGGCATAA

Upstream 100 bases:

>100_bases
CCTGCAACTCGCGGACGATGCGGCGGGCGCCGGGGGCGGAACGAACGGCGGCACGGCACCCGCCAAGACAAGAGCAACTG
TGCAGACAAAGGCAGCGTAA

Downstream 100 bases:

>100_bases
TTTTTTTGCACAAAGGGCTTGATCGGTGTTTGGCGCATTGCTATAATCTTTTTTCTTCGTGGCCCGGTAGCTCAGTTGGT
AGAGCAGCGGATTGAAAATC

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MATILVVDDEMGIRELLSEILSDEGHVVDVAENAQAARDYRLRHAPDLVLLDIWMPDTDGVTLLKEWASQGQLTMPVIMM
SGHATIDTAVEATKIGALDFLEKPITLQKLLKSVEHGLARGAAPLPASAATKPAAGASSVASAAALPMLGDDPAAALAGQ
TTAAIPFDIPLREARDAFERAYFEYHLARENGSMTRVAEKTGLERTHLYRKLKQLGVELGKKPAEGAA

Sequences:

>Translated_228_residues
MATILVVDDEMGIRELLSEILSDEGHVVDVAENAQAARDYRLRHAPDLVLLDIWMPDTDGVTLLKEWASQGQLTMPVIMM
SGHATIDTAVEATKIGALDFLEKPITLQKLLKSVEHGLARGAAPLPASAATKPAAGASSVASAAALPMLGDDPAAALAGQ
TTAAIPFDIPLREARDAFERAYFEYHLARENGSMTRVAEKTGLERTHLYRKLKQLGVELGKKPAEGAA
>Mature_227_residues
ATILVVDDEMGIRELLSEILSDEGHVVDVAENAQAARDYRLRHAPDLVLLDIWMPDTDGVTLLKEWASQGQLTMPVIMMS
GHATIDTAVEATKIGALDFLEKPITLQKLLKSVEHGLARGAAPLPASAATKPAAGASSVASAAALPMLGDDPAAALAGQT
TAAIPFDIPLREARDAFERAYFEYHLARENGSMTRVAEKTGLERTHLYRKLKQLGVELGKKPAEGAA

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=115, Percent_Identity=40.8695652173913, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1790437, Length=151, Percent_Identity=32.4503311258278, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1787375, Length=129, Percent_Identity=31.0077519379845, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1789809, Length=134, Percent_Identity=32.089552238806, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1790299, Length=116, Percent_Identity=35.3448275862069, Blast_Score=70, Evalue=8e-14,
Organism=Escherichia coli, GI1786784, Length=125, Percent_Identity=33.6, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786911, Length=126, Percent_Identity=31.7460317460317, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 24361; Mature: 24230

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATILVVDDEMGIRELLSEILSDEGHVVDVAENAQAARDYRLRHAPDLVLLDIWMPDTDG
CEEEEEEECCCCHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHCCCCCEEEEEEECCCCCC
VTLLKEWASQGQLTMPVIMMSGHATIDTAVEATKIGALDFLEKPITLQKLLKSVEHGLAR
HHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHC
GAAPLPASAATKPAAGASSVASAAALPMLGDDPAAALAGQTTAAIPFDIPLREARDAFER
CCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHCCCCCEECCCCCCHHHHHHHHHH
AYFEYHLARENGSMTRVAEKTGLERTHLYRKLKQLGVELGKKPAEGAA
HHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
ATILVVDDEMGIRELLSEILSDEGHVVDVAENAQAARDYRLRHAPDLVLLDIWMPDTDG
EEEEEEECCCCHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHCCCCCEEEEEEECCCCCC
VTLLKEWASQGQLTMPVIMMSGHATIDTAVEATKIGALDFLEKPITLQKLLKSVEHGLAR
HHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHC
GAAPLPASAATKPAAGASSVASAAALPMLGDDPAAALAGQTTAAIPFDIPLREARDAFER
CCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHCCCCCEECCCCCCHHHHHHHHHH
AYFEYHLARENGSMTRVAEKTGLERTHLYRKLKQLGVELGKKPAEGAA
HHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11243806 [H]