BacMap

Definition	Burkholderia thailandensis E264 chromosome chromosome I, complete sequence.
Accession	NC_007651
Length	3,809,201

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The map label for this gene is paaB [H]

Identifier: 83718849

GI number: 83718849

Start: 3337835

End: 3338626

Strand: Direct

Name: paaB [H]

Synonym: BTH_I2902

Alternate gene names: 83718849

Gene position: 3337835-3338626 (Clockwise)

Preceding gene: 83719929

Following gene: 83721405

Centisome position: 87.63

GC content: 65.78

Gene sequence:

>792_bases
ATGTCCTACCAAGCGATTCGCATCGACATCGATCCGGCAGCACAGATCGCGACGATCACGCTCGATCGCCCCGACAAGCT
CAACAGCTTCACGCGCAACATGCATCGCGAGCTGCAGTCGGCGCTCGACGACGTGCAGGCCGCCAACGCGCGCGCATTGA
TTCTCACGGGCGCGGGCCGCGGCTTCTGCGCGGGCCAGGATCTTGCCGACCTCGATTTCACACCTGGGGCGATGACCGAT
CTCGGCGACATGATCGAAGCGCATTTCAATCCGCTCATTCGCCGCCTGCAAGCGCTGCCGCTGCCCGTCATCGCCGCCGT
GAACGGCATCGCGGCGGGCGCAGGCGCCAATCTGGCGTTCGCGTGCGATCTCGTCATCGCGGCGAAATCGAGCAGTTTCA
TTCAATCGTTCGTGAAGATCGGCCTCGTTCCGGATTCCGGCGGCACGTGGTTCCTGCCGCAGCGCGTCGGCTTCGCCCGC
GCGCTCGGCCTCGCGCTGACGGGCGACAAACTCGGGGCCGAACAGGCGGAGCGTTGGGGGCTCGTGTGGCGCGTCGTCGA
CGATGCCGAACTCACCGGTACCGCCTCGCAACTCGCCCGACAACTCGCGCAGCAGCCGACACGAGCGATCGCGGCAATCA
AGCAGGCGATGCGGTCGAGCGTCACCAACACGCTCGACCAACAGCTCGATGTCGAACGCGACCTTCAGCGCGAGCTCGGG
CAATCGTACGACTACGCGGAGGGCGTGCGCGCGTTCATCGAAAAGCGCGCCCCTCGCTTCGAAGGACGCTGA

Upstream 100 bases:

>100_bases
GTCGGGCAGGGCATCGCGATCGCGATCGAGCGCGTATAAGACGAGCCGGCAGGCGAAGGACGCATCCCGTTCATTTCGAA
GGCATGACAGGAGACAGCCG

Downstream 100 bases:

>100_bases
GATGACCGAACGCTCTCCCACGGCAACCGCCGAACGCTCCGCCGAAGCGCTTGCCCGCGCGACCGCCGAAGCAATGTTTG
CCGCGGACGCCTGCAGCCGC

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MSYQAIRIDIDPAAQIATITLDRPDKLNSFTRNMHRELQSALDDVQAANARALILTGAGRGFCAGQDLADLDFTPGAMTD
LGDMIEAHFNPLIRRLQALPLPVIAAVNGIAAGAGANLAFACDLVIAAKSSSFIQSFVKIGLVPDSGGTWFLPQRVGFAR
ALGLALTGDKLGAEQAERWGLVWRVVDDAELTGTASQLARQLAQQPTRAIAAIKQAMRSSVTNTLDQQLDVERDLQRELG
QSYDYAEGVRAFIEKRAPRFEGR

Sequences:

>Translated_263_residues
MSYQAIRIDIDPAAQIATITLDRPDKLNSFTRNMHRELQSALDDVQAANARALILTGAGRGFCAGQDLADLDFTPGAMTD
LGDMIEAHFNPLIRRLQALPLPVIAAVNGIAAGAGANLAFACDLVIAAKSSSFIQSFVKIGLVPDSGGTWFLPQRVGFAR
ALGLALTGDKLGAEQAERWGLVWRVVDDAELTGTASQLARQLAQQPTRAIAAIKQAMRSSVTNTLDQQLDVERDLQRELG
QSYDYAEGVRAFIEKRAPRFEGR
>Mature_262_residues
SYQAIRIDIDPAAQIATITLDRPDKLNSFTRNMHRELQSALDDVQAANARALILTGAGRGFCAGQDLADLDFTPGAMTDL
GDMIEAHFNPLIRRLQALPLPVIAAVNGIAAGAGANLAFACDLVIAAKSSSFIQSFVKIGLVPDSGGTWFLPQRVGFARA
LGLALTGDKLGAEQAERWGLVWRVVDDAELTGTASQLARQLAQQPTRAIAAIKQAMRSSVTNTLDQQLDVERDLQRELGQ
SYDYAEGVRAFIEKRAPRFEGR

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=247, Percent_Identity=31.9838056680162, Blast_Score=124, Evalue=9e-29,
Organism=Homo sapiens, GI31542718, Length=261, Percent_Identity=29.5019157088123, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI70995211, Length=268, Percent_Identity=28.7313432835821, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI4502327, Length=260, Percent_Identity=28.8461538461538, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI45643119, Length=204, Percent_Identity=26.9607843137255, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI260275230, Length=204, Percent_Identity=26.9607843137255, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI260274832, Length=204, Percent_Identity=26.9607843137255, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI213417737, Length=224, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI221136756, Length=238, Percent_Identity=26.4705882352941, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI221136753, Length=238, Percent_Identity=26.4705882352941, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI157694516, Length=224, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI25453481, Length=247, Percent_Identity=25.9109311740891, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI51538573, Length=247, Percent_Identity=25.9109311740891, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI4757968, Length=247, Percent_Identity=25.9109311740891, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI49355787, Length=247, Percent_Identity=25.9109311740891, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI221307494, Length=238, Percent_Identity=26.4705882352941, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI20127408, Length=188, Percent_Identity=27.6595744680851, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI4757966, Length=241, Percent_Identity=26.1410788381743, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI51538581, Length=241, Percent_Identity=26.1410788381743, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI37594469, Length=181, Percent_Identity=32.5966850828729, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI37594471, Length=179, Percent_Identity=31.8435754189944, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI157694520, Length=205, Percent_Identity=28.2926829268293, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI116235487, Length=231, Percent_Identity=22.9437229437229, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI68989263, Length=192, Percent_Identity=27.6041666666667, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1787660, Length=250, Percent_Identity=57.6, Blast_Score=263, Evalue=1e-71,
Organism=Escherichia coli, GI221142681, Length=266, Percent_Identity=38.7218045112782, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1787659, Length=253, Percent_Identity=35.5731225296443, Blast_Score=128, Evalue=5e-31,
Organism=Escherichia coli, GI87082183, Length=270, Percent_Identity=28.8888888888889, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1788597, Length=249, Percent_Identity=30.9236947791165, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788682, Length=201, Percent_Identity=30.3482587064677, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1790281, Length=189, Percent_Identity=30.6878306878307, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25145438, Length=249, Percent_Identity=34.9397590361446, Blast_Score=147, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI17554946, Length=262, Percent_Identity=30.5343511450382, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17549921, Length=233, Percent_Identity=28.3261802575107, Blast_Score=109, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17535521, Length=254, Percent_Identity=27.9527559055118, Blast_Score=100, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17536985, Length=266, Percent_Identity=27.4436090225564, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17560910, Length=244, Percent_Identity=27.4590163934426, Blast_Score=97, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17540306, Length=242, Percent_Identity=31.404958677686, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17540714, Length=221, Percent_Identity=28.9592760180996, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17534483, Length=225, Percent_Identity=25.7777777777778, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI25144276, Length=184, Percent_Identity=29.3478260869565, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17508951, Length=184, Percent_Identity=29.3478260869565, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17508953, Length=184, Percent_Identity=29.3478260869565, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17558304, Length=219, Percent_Identity=25.1141552511416, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI20129971, Length=261, Percent_Identity=30.2681992337165, Blast_Score=134, Evalue=6e-32,
Organism=Drosophila melanogaster, GI24653477, Length=261, Percent_Identity=30.2681992337165, Blast_Score=134, Evalue=6e-32,
Organism=Drosophila melanogaster, GI24653139, Length=254, Percent_Identity=31.8897637795276, Blast_Score=106, Evalue=1e-23,
Organism=Drosophila melanogaster, GI19922422, Length=250, Percent_Identity=27.2, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24654903, Length=263, Percent_Identity=25.4752851711027, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI19920382, Length=258, Percent_Identity=29.8449612403101, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21357171, Length=257, Percent_Identity=28.4046692607004, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24650670, Length=211, Percent_Identity=28.436018957346, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR011968 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 28393; Mature: 28261

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYQAIRIDIDPAAQIATITLDRPDKLNSFTRNMHRELQSALDDVQAANARALILTGAGR
CCCEEEEEECCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCC
GFCAGQDLADLDFTPGAMTDLGDMIEAHFNPLIRRLQALPLPVIAAVNGIAAGAGANLAF
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHH
ACDLVIAAKSSSFIQSFVKIGLVPDSGGTWFLPQRVGFARALGLALTGDKLGAEQAERWG
EEHHHHCCCCHHHHHHHHHHCCEECCCCCEECHHHHHHHHHHHHHCCCCHHCHHHHHHCC
LVWRVVDDAELTGTASQLARQLAQQPTRAIAAIKQAMRSSVTNTLDQQLDVERDLQRELG
EEEEEECCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHC
QSYDYAEGVRAFIEKRAPRFEGR
CCCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SYQAIRIDIDPAAQIATITLDRPDKLNSFTRNMHRELQSALDDVQAANARALILTGAGR
CCEEEEEECCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCC
GFCAGQDLADLDFTPGAMTDLGDMIEAHFNPLIRRLQALPLPVIAAVNGIAAGAGANLAF
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHH
ACDLVIAAKSSSFIQSFVKIGLVPDSGGTWFLPQRVGFARALGLALTGDKLGAEQAERWG
EEHHHHCCCCHHHHHHHHHHCCEECCCCCEECHHHHHHHHHHHHHCCCCHHCHHHHHHCC
LVWRVVDDAELTGTASQLARQLAQQPTRAIAAIKQAMRSSVTNTLDQQLDVERDLQRELG
EEEEEECCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHC
QSYDYAEGVRAFIEKRAPRFEGR
CCCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]