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The map label for this gene is aceE [H]

Identifier: 83718787

GI number: 83718787

Start: 2106534

End: 2109230

Strand: Direct

Name: aceE [H]

Synonym: BTH_I1864

Alternate gene names: 83718787

Gene position: 2106534-2109230 (Clockwise)

Preceding gene: 161723133

Following gene: 83720698

Centisome position: 55.3

GC content: 65.44

Gene sequence:

>2697_bases
ATGTCCGCTGTACCGAATGAAGTGATGAAGTACGTCGCAGCCGAACGCGACGACGACGCGCAGGAAACCGTCGAATGGCT
CGAAGCGCTTGACGGCGTGATTTCCTCGGTCGGCCCCGGCCGCGCGCACTACCTGATCGAGAAGCAGATTGAATTCGCGC
GGATGCACGGCGAGCACCTGCCGTTCTCCGCGAACACCCCGTACATCAACACGATTCCCGTCGAAGCCCAGGCGAAGATT
CCGGGCGACCAGGACATCGAGCACCGGATCCGCTCGTACACGCGCTGGAACGCGATCGCGATGGTGCTGCGCGCGGGCAA
GGACACGAACGTCGGCGGCCACATCGCGTCGTTCGCGTCGGCCGCGACCTTGTATGACGTCGGCTACAACCACTTCTGGC
ACGCGCCGTCCGCCGAGCACGGCGGCGATCTCGTGTTCGTGCAGGGCCACTCGTCGCCGGGCGTGTACTCGCGCGCGTTC
CTGCTTGGCCGCCTGTCGGAAGAGCAGCTCGACAACTTCCGCCAGGAAGTCGGCGGCAACGGCATCTCGTCGTATCCGCA
CCCGTGGCTGATGCCGGACTTCTGGCAGTTCCCGACCGTGTCGATGGGCCTCGGCCCGATCATGGCGATCTACCAGGCGC
GCTTCATGAAGTACCTGGAATCGCGCGGCATCGCGAAGACCGCCGGCCGCAAGGTCTGGGCGTTCCTCGGCGACGGCGAG
ACGGACGAGCCGGAATCGCTCGGCGCGATCGGCATGGCGAGCCGCGAGAAGCTCGACAATCTCGTGTTCGTGATCAACTG
CAACCTGCAGCGCCTGGACGGCCCGGTGCGCGGCAACGGCAAGATCATCCAGGAGCTGGAATCGGAATTCCGCGGCGCGG
GCTGGAACGTGATCAAGGTGATCTGGGGCAGCCGCTGGGATGCGCTCTTCGCGCGCGACAAGACGGGCGCGCTGATGCGC
CGGATGATGGAGGTCGTCGACGGCGAGTACCAGACGTACAAGTCGGAGTCGGGCGCGTACGTGCGCGAGCATTTCTTCAA
CACGCCCGAGCTGAAGGCGCTCGTGGCCGACTGGTCCGACGACGACATCTGGAACCTGAACCGCGGCGGCCACGATCCGC
ACAAGATCTACGCGGCGTTCCACGCGGCGAGCAACTCGAAGGGCGCGCCGACCGTGATCCTCGCGAAGACCATCAAGGGC
TACGGGATGGGCGAGTCGGGCCAGGCGATGAATATCACGCACCAGCAGAAGAAGCTGCCCGTCGAGCAACTGAAGAAGTT
CCGCGACCAGTTCCGCCTGCCGATCACCGACGAGCAGATCGCCGACGTGCCGTACGTGAAGTTCGAGGAAGGCTCGAAGG
AGCTCGAATACATGCGCAAGCAGCGCATGGACCTCGGCGGCTACCTGCCGCAGCGCCGCCAGAAGGCCGAGTCGCTGCCG
GTGCCGCCGCTCGAGGCGTTCGAGCCGCTCTTGAAGGGCACGGGCGAAGGCCGCGAGATCTCGACGACGATGGCGTTCGT
GCGAATCCTGAACATCCTGCTGAAGGACAAGACGCTCGGCAAGCGCGTCGTGCCGATCGTGCCGGACGAGTCGCGCACGT
TCGGCATGGAGGGCCTGTTCCGCCAGATCGGCATCTGGAACCAGGAAGGCCAGAAATACGTGCCGGAGGATTCCGACCAG
CTGATGTTCTACAAGGAATCGGAAACCGGCCAGATCCTGCAGGAAGGCATCAACGAAGCGGGCGGCATGTGCGACTGGAT
CGCGGCGGCGACGTCGTACTCGACGCACGGCGAGATCATGGTGCCGTTCTACATCTTCTATTCGATGTTCGGCTTCCAGC
GGATCGGCGACCTCGCATGGGCGGCGGGCGACATGCGCTCGCGCGGCTTCCTGCTCGGCGGCACGGCGGGCCGCACGACG
CTCAACGGCGAAGGCCTGCAGCACGAGGACGGCCACTCGCTGATGTGGGCGGCATCGGTGCCGAACTGCGTGAGCTACGA
TCCGACGTTCGGCTACGAGCTCGCCGTCATCATGCAGGACGGCCTGCGCCGCATGGTGCAGGAGCAGGAGGACGTCTACT
ACTACGTGACGGTGATGAACGAGAACTACGAGCACCCGGCGATCCCGCAGGGCGAGCACGTGGCGGCCGACATCATCAAG
GGCATGTACTCGTTCAAGAAGGCCGACGCCGACAAGAAGGCGCCGCGCGTTCAACTGCTCGGCGCGGGCACGATCTTCAA
CGAAGTGATCGCCGCCGCCGAGCTTTTGAAGAACGACTGGGGCGTCGCGGCCGATCTCTGGAGCGTGCCGAGCTTCACCG
AGCTTGCGCGCGAGGGCCACGAGGTCGAGCGCTGGAACCTGCTGCATCCGGCCGAGCCGCGCCGCCTGTCGCACGTGCAG
AAATGCCTGAAGGACACGCAAGGCCCGGTGATCGCGTCGACCGACTACGTGCGCGCGCTCGCCGACCAGATTCGCGGCCA
GATCGATCGCCGCTACGTCGTGCTCGGCACCGACGGCTTCGGCCGCTCGGACACGCGCAAGGCGCTGCGCCACTTCTTCG
AGGTGGATCGTTACTGGGTCACGGTCGCGGCGCTCAACGCGCTTGCCGACGAGGGTGCGATCGACCGCAAGGTCGTGGCG
GACGCCATCGCGAAGTACGACCTCGACCCGGCCAAACCCAACCCGATGACGGTTTAA

Upstream 100 bases:

>100_bases
CGTGTGACGCTCTTTACAATCCGCGGGAGCTTGTTGCAGCCGGCGGCATGCGTCGTCGCGCGAAGGCCATCTTCAATTCC
AGGACACCCAGGAGACGAGA

Downstream 100 bases:

>100_bases
CGCACGCGCCGCGTGACGTCGCGCGCCCGCTCCCGCTTTCGACGATTTCGGCGAACGAAGGCGGGACGGACGGCGCGGCT
TGCGCCTTGCATGGGATCGG

Product: pyruvate dehydrogenase subunit E1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 898; Mature: 897

Protein sequence:

>898_residues
MSAVPNEVMKYVAAERDDDAQETVEWLEALDGVISSVGPGRAHYLIEKQIEFARMHGEHLPFSANTPYINTIPVEAQAKI
PGDQDIEHRIRSYTRWNAIAMVLRAGKDTNVGGHIASFASAATLYDVGYNHFWHAPSAEHGGDLVFVQGHSSPGVYSRAF
LLGRLSEEQLDNFRQEVGGNGISSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFMKYLESRGIAKTAGRKVWAFLGDGE
TDEPESLGAIGMASREKLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKVIWGSRWDALFARDKTGALMR
RMMEVVDGEYQTYKSESGAYVREHFFNTPELKALVADWSDDDIWNLNRGGHDPHKIYAAFHAASNSKGAPTVILAKTIKG
YGMGESGQAMNITHQQKKLPVEQLKKFRDQFRLPITDEQIADVPYVKFEEGSKELEYMRKQRMDLGGYLPQRRQKAESLP
VPPLEAFEPLLKGTGEGREISTTMAFVRILNILLKDKTLGKRVVPIVPDESRTFGMEGLFRQIGIWNQEGQKYVPEDSDQ
LMFYKESETGQILQEGINEAGGMCDWIAAATSYSTHGEIMVPFYIFYSMFGFQRIGDLAWAAGDMRSRGFLLGGTAGRTT
LNGEGLQHEDGHSLMWAASVPNCVSYDPTFGYELAVIMQDGLRRMVQEQEDVYYYVTVMNENYEHPAIPQGEHVAADIIK
GMYSFKKADADKKAPRVQLLGAGTIFNEVIAAAELLKNDWGVAADLWSVPSFTELAREGHEVERWNLLHPAEPRRLSHVQ
KCLKDTQGPVIASTDYVRALADQIRGQIDRRYVVLGTDGFGRSDTRKALRHFFEVDRYWVTVAALNALADEGAIDRKVVA
DAIAKYDLDPAKPNPMTV

Sequences:

>Translated_898_residues
MSAVPNEVMKYVAAERDDDAQETVEWLEALDGVISSVGPGRAHYLIEKQIEFARMHGEHLPFSANTPYINTIPVEAQAKI
PGDQDIEHRIRSYTRWNAIAMVLRAGKDTNVGGHIASFASAATLYDVGYNHFWHAPSAEHGGDLVFVQGHSSPGVYSRAF
LLGRLSEEQLDNFRQEVGGNGISSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFMKYLESRGIAKTAGRKVWAFLGDGE
TDEPESLGAIGMASREKLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKVIWGSRWDALFARDKTGALMR
RMMEVVDGEYQTYKSESGAYVREHFFNTPELKALVADWSDDDIWNLNRGGHDPHKIYAAFHAASNSKGAPTVILAKTIKG
YGMGESGQAMNITHQQKKLPVEQLKKFRDQFRLPITDEQIADVPYVKFEEGSKELEYMRKQRMDLGGYLPQRRQKAESLP
VPPLEAFEPLLKGTGEGREISTTMAFVRILNILLKDKTLGKRVVPIVPDESRTFGMEGLFRQIGIWNQEGQKYVPEDSDQ
LMFYKESETGQILQEGINEAGGMCDWIAAATSYSTHGEIMVPFYIFYSMFGFQRIGDLAWAAGDMRSRGFLLGGTAGRTT
LNGEGLQHEDGHSLMWAASVPNCVSYDPTFGYELAVIMQDGLRRMVQEQEDVYYYVTVMNENYEHPAIPQGEHVAADIIK
GMYSFKKADADKKAPRVQLLGAGTIFNEVIAAAELLKNDWGVAADLWSVPSFTELAREGHEVERWNLLHPAEPRRLSHVQ
KCLKDTQGPVIASTDYVRALADQIRGQIDRRYVVLGTDGFGRSDTRKALRHFFEVDRYWVTVAALNALADEGAIDRKVVA
DAIAKYDLDPAKPNPMTV
>Mature_897_residues
SAVPNEVMKYVAAERDDDAQETVEWLEALDGVISSVGPGRAHYLIEKQIEFARMHGEHLPFSANTPYINTIPVEAQAKIP
GDQDIEHRIRSYTRWNAIAMVLRAGKDTNVGGHIASFASAATLYDVGYNHFWHAPSAEHGGDLVFVQGHSSPGVYSRAFL
LGRLSEEQLDNFRQEVGGNGISSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFMKYLESRGIAKTAGRKVWAFLGDGET
DEPESLGAIGMASREKLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKVIWGSRWDALFARDKTGALMRR
MMEVVDGEYQTYKSESGAYVREHFFNTPELKALVADWSDDDIWNLNRGGHDPHKIYAAFHAASNSKGAPTVILAKTIKGY
GMGESGQAMNITHQQKKLPVEQLKKFRDQFRLPITDEQIADVPYVKFEEGSKELEYMRKQRMDLGGYLPQRRQKAESLPV
PPLEAFEPLLKGTGEGREISTTMAFVRILNILLKDKTLGKRVVPIVPDESRTFGMEGLFRQIGIWNQEGQKYVPEDSDQL
MFYKESETGQILQEGINEAGGMCDWIAAATSYSTHGEIMVPFYIFYSMFGFQRIGDLAWAAGDMRSRGFLLGGTAGRTTL
NGEGLQHEDGHSLMWAASVPNCVSYDPTFGYELAVIMQDGLRRMVQEQEDVYYYVTVMNENYEHPAIPQGEHVAADIIKG
MYSFKKADADKKAPRVQLLGAGTIFNEVIAAAELLKNDWGVAADLWSVPSFTELAREGHEVERWNLLHPAEPRRLSHVQK
CLKDTQGPVIASTDYVRALADQIRGQIDRRYVVLGTDGFGRSDTRKALRHFFEVDRYWVTVAALNALADEGAIDRKVVAD
AIAKYDLDPAKPNPMTV

Specific function: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components:pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydroge

COG id: COG2609

COG function: function code C; Pyruvate dehydrogenase complex, dehydrogenase (E1) component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786304, Length=885, Percent_Identity=60, Blast_Score=1085, Evalue=0.0,

Paralogues:

None

Copy number: 1140 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 400 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004660
- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =1.2.4.1 [H]

Molecular weight: Translated: 100579; Mature: 100448

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAVPNEVMKYVAAERDDDAQETVEWLEALDGVISSVGPGRAHYLIEKQIEFARMHGEHL
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCC
PFSANTPYINTIPVEAQAKIPGDQDIEHRIRSYTRWNAIAMVLRAGKDTNVGGHIASFAS
CCCCCCCEEEEECCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
AATLYDVGYNHFWHAPSAEHGGDLVFVQGHSSPGVYSRAFLLGRLSEEQLDNFRQEVGGN
HHHHHHCCCCCEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCC
GISSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFMKYLESRGIAKTAGRKVWAFLGDGE
CCCCCCCCCCCCCCCCCCCCHHCHHHHHHHHHHHHHHHHHHCCCHHHCCCEEEEEECCCC
TDEPESLGAIGMASREKLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKV
CCCCHHCCCCCCCCHHHHCCEEEEEECCHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEE
IWGSRWDALFARDKTGALMRRMMEVVDGEYQTYKSESGAYVREHFFNTPELKALVADWSD
ECCCCCHHHHCCCHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHCCCCCHHHHEEECCCC
DDIWNLNRGGHDPHKIYAAFHAASNSKGAPTVILAKTIKGYGMGESGQAMNITHQQKKLP
CCCEECCCCCCCHHHHHHHHHHCCCCCCCCEEEEEEHHCCCCCCCCCCEECCCHHHHCCC
VEQLKKFRDQFRLPITDEQIADVPYVKFEEGSKELEYMRKQRMDLGGYLPQRRQKAESLP
HHHHHHHHHHCCCCCCCHHHCCCCCEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHCCC
VPPLEAFEPLLKGTGEGREISTTMAFVRILNILLKDKTLGKRVVPIVPDESRTFGMEGLF
CCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHH
RQIGIWNQEGQKYVPEDSDQLMFYKESETGQILQEGINEAGGMCDWIAAATSYSTHGEIM
HHHCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEE
VPFYIFYSMFGFQRIGDLAWAAGDMRSRGFLLGGTAGRTTLNGEGLQHEDGHSLMWAASV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEECCCCCCCCCCCEEEEECCC
PNCVSYDPTFGYELAVIMQDGLRRMVQEQEDVYYYVTVMNENYEHPAIPQGEHVAADIIK
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHH
GMYSFKKADADKKAPRVQLLGAGTIFNEVIAAAELLKNDWGVAADLWSVPSFTELAREGH
HHHHHHHCCCCCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHCCC
EVERWNLLHPAEPRRLSHVQKCLKDTQGPVIASTDYVRALADQIRGQIDRRYVVLGTDGF
CCHHCCCCCCCCCHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHCCCCEEEEEECCCC
GRSDTRKALRHFFEVDRYWVTVAALNALADEGAIDRKVVADAIAKYDLDPAKPNPMTV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SAVPNEVMKYVAAERDDDAQETVEWLEALDGVISSVGPGRAHYLIEKQIEFARMHGEHL
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCC
PFSANTPYINTIPVEAQAKIPGDQDIEHRIRSYTRWNAIAMVLRAGKDTNVGGHIASFAS
CCCCCCCEEEEECCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
AATLYDVGYNHFWHAPSAEHGGDLVFVQGHSSPGVYSRAFLLGRLSEEQLDNFRQEVGGN
HHHHHHCCCCCEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCC
GISSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFMKYLESRGIAKTAGRKVWAFLGDGE
CCCCCCCCCCCCCCCCCCCCHHCHHHHHHHHHHHHHHHHHHCCCHHHCCCEEEEEECCCC
TDEPESLGAIGMASREKLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKV
CCCCHHCCCCCCCCHHHHCCEEEEEECCHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEE
IWGSRWDALFARDKTGALMRRMMEVVDGEYQTYKSESGAYVREHFFNTPELKALVADWSD
ECCCCCHHHHCCCHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHCCCCCHHHHEEECCCC
DDIWNLNRGGHDPHKIYAAFHAASNSKGAPTVILAKTIKGYGMGESGQAMNITHQQKKLP
CCCEECCCCCCCHHHHHHHHHHCCCCCCCCEEEEEEHHCCCCCCCCCCEECCCHHHHCCC
VEQLKKFRDQFRLPITDEQIADVPYVKFEEGSKELEYMRKQRMDLGGYLPQRRQKAESLP
HHHHHHHHHHCCCCCCCHHHCCCCCEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHCCC
VPPLEAFEPLLKGTGEGREISTTMAFVRILNILLKDKTLGKRVVPIVPDESRTFGMEGLF
CCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHH
RQIGIWNQEGQKYVPEDSDQLMFYKESETGQILQEGINEAGGMCDWIAAATSYSTHGEIM
HHHCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEE
VPFYIFYSMFGFQRIGDLAWAAGDMRSRGFLLGGTAGRTTLNGEGLQHEDGHSLMWAASV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEECCCCCCCCCCCEEEEECCC
PNCVSYDPTFGYELAVIMQDGLRRMVQEQEDVYYYVTVMNENYEHPAIPQGEHVAADIIK
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHH
GMYSFKKADADKKAPRVQLLGAGTIFNEVIAAAELLKNDWGVAADLWSVPSFTELAREGH
HHHHHHHCCCCCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHCCC
EVERWNLLHPAEPRRLSHVQKCLKDTQGPVIASTDYVRALADQIRGQIDRRYVVLGTDGF
CCHHCCCCCCCCCHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHCCCCEEEEEECCCC
GRSDTRKALRHFFEVDRYWVTVAALNALADEGAIDRKVVADAIAKYDLDPAKPNPMTV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8021225 [H]