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The map label for this gene is mltA [H]

Identifier: 83718768

GI number: 83718768

Start: 3340754

End: 3342055

Strand: Reverse

Name: mltA [H]

Synonym: BTH_I2905

Alternate gene names: 83718768

Gene position: 3342055-3340754 (Counterclockwise)

Preceding gene: 83720888

Following gene: 83721196

Centisome position: 87.74

GC content: 68.36

Gene sequence:

>1302_bases
TTGGGGCGCTGTCAGCGCTGGGGCTTGTCGTGCCGGCCGGGCTGCTTCTTCTTGCCCGAAGCCGTCCAGACGACGATGAA
TATGAGCAGGGCGAGCGCCAGCAACGATTCCAGCGCAAAGATGAGCATCGGGTATTGGTCGAGCAGATCGGACATGGCGG
TTTCCATCAACAACGGACATTGTATGGGTTTTAGCCGGCGGCTTGCCGGGTGGGCTGCGGCCGTCGCGGCTGCGGCGCTT
CTTGCCGCATGCGGCGGCACGCCGGTGCGGCAGGCGTCGCGGCCCGCGGGTGCCGCGATCGTACCAGGGCAGATCGCGGC
TGCGCGACTCACGCCCGTCGCGTGGCAGCAGGTGCCGGGCTGGCAGGACGACAGCCTGATCGGCGCGACGATCGCGCTGC
GCGAGAACTGCGTACGCCTCGCGCGGCAGGCGAACTGGCAGCGCGCGTGCGCGGCCGCCGTGCGGCTCGACGATCTCGAC
GTCGGCAGTGCCCGCACCTTCTTCGAGACGTACTTCACGCCATTCCAGTTCGCGAATAACGACGGCACGCTCGACGGCCT
CGTGACCGGCTACTACGAACCGCTGCTGCACGGCTCGCGGGTTCGGCGTGGTCCGTATCAGTACGCGCTCTACCGCTGGC
CCGCCGGCTACCGCGCGGGCGCGTCGATGCCGGCACGCGCGCAGCTCATGCGCTCGGGCGTGCTGAACGGCAACGAGCTC
GTCTGGGTCGACGATCCGATCGAGGCGTTCTTCCTGCAGGTGCAAGGCTCGGGCCGGGTCGTCCTCGACGACGGTACGGT
GATGCGGGTCGGTTACGGCGGCACGAACAACCAGCCGTACCGCTCGATCGGCAAATGGCTGCTCGATCATGGCGAACTCA
GCGCCGGGCAGGCGACGATGCAGGGGATCAAGGCGTGGGCGCGCGCGAATCCGTCGCGTGTCGATGCGCTGCTCGACACC
AATCCTCGCTTTGTGTTCTTCCGCGAGATGCCGTCGCAGGAGGACGTGCCGCGCGGCGGCGCGGACGGCCCGGTGGGCGC
GCTCGGCGTGCCGCTCACGCCGGAGCGCTCGATCGCGGTTGATCCGTCGTCGATTCCGCTCGGCACGCCGGTGTTCCTGC
AGACGACGCGTCCGATGACGAATGCGCCGCTCAATCGCCTCGTGTTTGCGCAGGATGTCGGAACGGCGATCAGGGGCGGC
GTGCGGGCGGACTATTTCTGGGGGCTTGGCGACGACGCAGGCGACCAGGCCGGCCGGATGAAGCAGACCGGGCGGATGTG
GCTGCTGTTTCCCAATTCATGA

Upstream 100 bases:

>100_bases
CGGAGGACGGCGAGCGCTTCGAGGCGCCCGTCGACGAATTCGCGCTGCACATGCCGCGCACGCTGCACTGAGCGTGCGGG
CGCCGCCGGGGCGCGGCAGA

Downstream 100 bases:

>100_bases
GCGGCGCGTGAGCATGCGCGTGCGCGCGGCGAGCGTCGGGTGCTTGACCGCGTGAGTGCGATTGCGTGACCGCGCTGTGG
CCGCGCGAGCGTTGCATTGG

Product: membrane-bound lytic murein transglycosylase A

Products: Muramic Acid Residue [C]

Alternate protein names: Mlt38; Murein hydrolase A [H]

Number of amino acids: Translated: 433; Mature: 432

Protein sequence:

>433_residues
MGRCQRWGLSCRPGCFFLPEAVQTTMNMSRASASNDSSAKMSIGYWSSRSDMAVSINNGHCMGFSRRLAGWAAAVAAAAL
LAACGGTPVRQASRPAGAAIVPGQIAAARLTPVAWQQVPGWQDDSLIGATIALRENCVRLARQANWQRACAAAVRLDDLD
VGSARTFFETYFTPFQFANNDGTLDGLVTGYYEPLLHGSRVRRGPYQYALYRWPAGYRAGASMPARAQLMRSGVLNGNEL
VWVDDPIEAFFLQVQGSGRVVLDDGTVMRVGYGGTNNQPYRSIGKWLLDHGELSAGQATMQGIKAWARANPSRVDALLDT
NPRFVFFREMPSQEDVPRGGADGPVGALGVPLTPERSIAVDPSSIPLGTPVFLQTTRPMTNAPLNRLVFAQDVGTAIRGG
VRADYFWGLGDDAGDQAGRMKQTGRMWLLFPNS

Sequences:

>Translated_433_residues
MGRCQRWGLSCRPGCFFLPEAVQTTMNMSRASASNDSSAKMSIGYWSSRSDMAVSINNGHCMGFSRRLAGWAAAVAAAAL
LAACGGTPVRQASRPAGAAIVPGQIAAARLTPVAWQQVPGWQDDSLIGATIALRENCVRLARQANWQRACAAAVRLDDLD
VGSARTFFETYFTPFQFANNDGTLDGLVTGYYEPLLHGSRVRRGPYQYALYRWPAGYRAGASMPARAQLMRSGVLNGNEL
VWVDDPIEAFFLQVQGSGRVVLDDGTVMRVGYGGTNNQPYRSIGKWLLDHGELSAGQATMQGIKAWARANPSRVDALLDT
NPRFVFFREMPSQEDVPRGGADGPVGALGVPLTPERSIAVDPSSIPLGTPVFLQTTRPMTNAPLNRLVFAQDVGTAIRGG
VRADYFWGLGDDAGDQAGRMKQTGRMWLLFPNS
>Mature_432_residues
GRCQRWGLSCRPGCFFLPEAVQTTMNMSRASASNDSSAKMSIGYWSSRSDMAVSINNGHCMGFSRRLAGWAAAVAAAALL
AACGGTPVRQASRPAGAAIVPGQIAAARLTPVAWQQVPGWQDDSLIGATIALRENCVRLARQANWQRACAAAVRLDDLDV
GSARTFFETYFTPFQFANNDGTLDGLVTGYYEPLLHGSRVRRGPYQYALYRWPAGYRAGASMPARAQLMRSGVLNGNELV
WVDDPIEAFFLQVQGSGRVVLDDGTVMRVGYGGTNNQPYRSIGKWLLDHGELSAGQATMQGIKAWARANPSRVDALLDTN
PRFVFFREMPSQEDVPRGGADGPVGALGVPLTPERSIAVDPSSIPLGTPVFLQTTRPMTNAPLNRLVFAQDVGTAIRGGV
RADYFWGLGDDAGDQAGRMKQTGRMWLLFPNS

Specific function: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. Degrades murein glycan strands and insoluble, high-molecular weight murein sacculi [H]

COG id: COG2821

COG function: function code M; Membrane-bound lytic murein transglycosylase

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789179, Length=260, Percent_Identity=35.3846153846154, Blast_Score=135, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010611
- InterPro:   IPR014733
- InterPro:   IPR005300 [H]

Pfam domain/function: PF06725 3D; PF03562 MltA [H]

EC number: 3.2.1.- [C]

Molecular weight: Translated: 46760; Mature: 46628

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRCQRWGLSCRPGCFFLPEAVQTTMNMSRASASNDSSAKMSIGYWSSRSDMAVSINNGH
CCCCCCCCCCCCCCCEECHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEEEECCCE
CMGFSRRLAGWAAAVAAAALLAACGGTPVRQASRPAGAAIVPGQIAAARLTPVAWQQVPG
EECHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCEECCCCHHHHHCCCHHHHHCCC
WQDDSLIGATIALRENCVRLARQANWQRACAAAVRLDDLDVGSARTFFETYFTPFQFANN
CCCCCEEHHHHHHHHHHHHHHHHCCHHHHHHHHHEECCCCCCCHHHHHHHHCCCEEEECC
DGTLDGLVTGYYEPLLHGSRVRRGPYQYALYRWPAGYRAGASMPARAQLMRSGVLNGNEL
CCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHCCCCCCEE
VWVDDPIEAFFLQVQGSGRVVLDDGTVMRVGYGGTNNQPYRSIGKWLLDHGELSAGQATM
EEEECCCEEEEEEECCCCEEEEECCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCHHHH
QGIKAWARANPSRVDALLDTNPRFVFFREMPSQEDVPRGGADGPVGALGVPLTPERSIAV
HHHHHHHHCCHHHHHHEECCCCCEEEEECCCCCCCCCCCCCCCCCCEECCCCCCCCCEEE
DPSSIPLGTPVFLQTTRPMTNAPLNRLVFAQDVGTAIRGGVRADYFWGLGDDAGDQAGRM
CCCCCCCCCCEEEEECCCCCCCCHHHEEEHHHHHHHHHCCCCEEEEECCCCCCCCCCCCH
KQTGRMWLLFPNS
HHCCCEEEEECCC
>Mature Secondary Structure 
GRCQRWGLSCRPGCFFLPEAVQTTMNMSRASASNDSSAKMSIGYWSSRSDMAVSINNGH
CCCCCCCCCCCCCCEECHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEEEECCCE
CMGFSRRLAGWAAAVAAAALLAACGGTPVRQASRPAGAAIVPGQIAAARLTPVAWQQVPG
EECHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCEECCCCHHHHHCCCHHHHHCCC
WQDDSLIGATIALRENCVRLARQANWQRACAAAVRLDDLDVGSARTFFETYFTPFQFANN
CCCCCEEHHHHHHHHHHHHHHHHCCHHHHHHHHHEECCCCCCCHHHHHHHHCCCEEEECC
DGTLDGLVTGYYEPLLHGSRVRRGPYQYALYRWPAGYRAGASMPARAQLMRSGVLNGNEL
CCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHCCCCCCEE
VWVDDPIEAFFLQVQGSGRVVLDDGTVMRVGYGGTNNQPYRSIGKWLLDHGELSAGQATM
EEEECCCEEEEEEECCCCEEEEECCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCHHHH
QGIKAWARANPSRVDALLDTNPRFVFFREMPSQEDVPRGGADGPVGALGVPLTPERSIAV
HHHHHHHHCCHHHHHHEECCCCCEEEEECCCCCCCCCCCCCCCCCCEECCCCCCCCCEEE
DPSSIPLGTPVFLQTTRPMTNAPLNRLVFAQDVGTAIRGGVRADYFWGLGDDAGDQAGRM
CCCCCCCCCCEEEEECCCCCCCCHHHEEEHHHHHHHHHCCCCEEEEECCCCCCCCCCCCH
KQTGRMWLLFPNS
HHCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic [C]

General reaction: Cleavage Bond [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]