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The map label for this gene is rpiA [H]

Identifier: 83718667

GI number: 83718667

Start: 2869101

End: 2869808

Strand: Reverse

Name: rpiA [H]

Synonym: BTH_I2516

Alternate gene names: 83718667

Gene position: 2869808-2869101 (Counterclockwise)

Preceding gene: 83718870

Following gene: 83719594

Centisome position: 75.34

GC content: 67.94

Gene sequence:

>708_bases
TTGACGCTTCTCATGACCCAAGACGAACTCAAACGCCTCGTCGGCGAGGCCGCCGCCCGATACGTGACCGACAACGTGCC
GCAAGGCGCGGTGATCGGCGTCGGCACGGGCTCGACCGCCAACTGCTTCATCGACGCGCTCGCGGCCGTCAAGGATCGCT
ATCGCGGCGCGGTGTCGAGTTCGGTGGCGACGACCGAGCGCCTGAAGTCGCACGGCATCCGGGTGTTCGATCTGAACGAG
ATCGAATCGCTGCAGGTGTATGTCGACGGCGCCGACGAGATCGACGAAAGCGGCGCGATGATCAAGGGCGGCGGCGGCGC
GCTTACGCGCGAGAAGATCGTCGCTTCGGTCGCGGAAACGTTCGTCTGCATCGCCGATGCGAGCAAGCGCGTCGCGATGC
TCGGCCAGTTTCCGCTGCCCGTCGAGGTCGTGCCGATGGCGCGCACCGCGATCGGCCGCCGGCTTGCCGCGCTGGGCGGC
GTGCCCGTGCTGCGCGTGAAGCAGGACGGCACGCCGTACGTGACCGACAACGGCAACGAGATTCTCGACGTGAAGGGCTT
GCGGATCGACGATCCGCGCGCGCTCGAAGCGGCGATCAACGGCTGGCCCGGCGTCGTGACGGTCGGCCTGTTCGCGCAAC
GCGGCGCGGATCTCTGCCTGCTCGGCACCGAGCACGGCGTCGAGACGCTCCGTTACGCGGCACGTTAA

Upstream 100 bases:

>100_bases
GTGTCACGTCGCGCCGCGATCGCCGCCGCTGCCGTCGCAACGAAAATATCCGTCGGACGGAGCGTCTCCGGTAAACTTGT
GCTTTTCGCACTTCGATTGC

Downstream 100 bases:

>100_bases
ATAAATCATTCAATAATGAATTCGATGCGCTAAAGCAATAAAGTCGGTTAATTCCAATCATAAAAAATTGATTGCCGACG
CTTTGCCGCACCGTTCGATC

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI [H]

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MTLLMTQDELKRLVGEAAARYVTDNVPQGAVIGVGTGSTANCFIDALAAVKDRYRGAVSSSVATTERLKSHGIRVFDLNE
IESLQVYVDGADEIDESGAMIKGGGGALTREKIVASVAETFVCIADASKRVAMLGQFPLPVEVVPMARTAIGRRLAALGG
VPVLRVKQDGTPYVTDNGNEILDVKGLRIDDPRALEAAINGWPGVVTVGLFAQRGADLCLLGTEHGVETLRYAAR

Sequences:

>Translated_235_residues
MTLLMTQDELKRLVGEAAARYVTDNVPQGAVIGVGTGSTANCFIDALAAVKDRYRGAVSSSVATTERLKSHGIRVFDLNE
IESLQVYVDGADEIDESGAMIKGGGGALTREKIVASVAETFVCIADASKRVAMLGQFPLPVEVVPMARTAIGRRLAALGG
VPVLRVKQDGTPYVTDNGNEILDVKGLRIDDPRALEAAINGWPGVVTVGLFAQRGADLCLLGTEHGVETLRYAAR
>Mature_234_residues
TLLMTQDELKRLVGEAAARYVTDNVPQGAVIGVGTGSTANCFIDALAAVKDRYRGAVSSSVATTERLKSHGIRVFDLNEI
ESLQVYVDGADEIDESGAMIKGGGGALTREKIVASVAETFVCIADASKRVAMLGQFPLPVEVVPMARTAIGRRLAALGGV
PVLRVKQDGTPYVTDNGNEILDVKGLRIDDPRALEAAINGWPGVVTVGLFAQRGADLCLLGTEHGVETLRYAAR

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI94536842, Length=235, Percent_Identity=36.1702127659575, Blast_Score=117, Evalue=6e-27,
Organism=Escherichia coli, GI1789280, Length=226, Percent_Identity=64.1592920353982, Blast_Score=273, Evalue=6e-75,
Organism=Caenorhabditis elegans, GI17551758, Length=215, Percent_Identity=38.1395348837209, Blast_Score=102, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6324669, Length=230, Percent_Identity=29.5652173913043, Blast_Score=88, Evalue=1e-18,
Organism=Drosophila melanogaster, GI281364072, Length=222, Percent_Identity=35.1351351351351, Blast_Score=102, Evalue=2e-22,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004788
- InterPro:   IPR020672 [H]

Pfam domain/function: PF06026 Rib_5-P_isom_A [H]

EC number: =5.3.1.6 [H]

Molecular weight: Translated: 24810; Mature: 24679

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS00063 ALDOKETO_REDUCTASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLLMTQDELKRLVGEAAARYVTDNVPQGAVIGVGTGSTANCFIDALAAVKDRYRGAVSS
CEEEECHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
SVATTERLKSHGIRVFDLNEIESLQVYVDGADEIDESGAMIKGGGGALTREKIVASVAET
HHHHHHHHHHCCCEEEECCCCCEEEEEECCCHHHCCCCCEEECCCCCHHHHHHHHHHHHH
FVCIADASKRVAMLGQFPLPVEVVPMARTAIGRRLAALGGVPVLRVKQDGTPYVTDNGNE
HEEEECCCCCEEEECCCCCCEEEECHHHHHHHHHHHHHCCCCEEEEECCCCCEEECCCCE
ILDVKGLRIDDPRALEAAINGWPGVVTVGLFAQRGADLCLLGTEHGVETLRYAAR
EEEECCCEECCCHHHHHHHCCCCCHHEEHHHHHCCCCEEEEECCCCHHHHHHHCC
>Mature Secondary Structure 
TLLMTQDELKRLVGEAAARYVTDNVPQGAVIGVGTGSTANCFIDALAAVKDRYRGAVSS
EEEECHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
SVATTERLKSHGIRVFDLNEIESLQVYVDGADEIDESGAMIKGGGGALTREKIVASVAET
HHHHHHHHHHCCCEEEECCCCCEEEEEECCCHHHCCCCCEEECCCCCHHHHHHHHHHHHH
FVCIADASKRVAMLGQFPLPVEVVPMARTAIGRRLAALGGVPVLRVKQDGTPYVTDNGNE
HEEEECCCCCEEEECCCCCCEEEECHHHHHHHHHHHHHCCCCEEEEECCCCCEEECCCCE
ILDVKGLRIDDPRALEAAINGWPGVVTVGLFAQRGADLCLLGTEHGVETLRYAAR
EEEECCCEECCCHHHHHHHCCCCCHHEEHHHHHCCCCEEEEECCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA