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The map label for this gene is paaN [H]

Identifier: 83718561

GI number: 83718561

Start: 3334776

End: 3336482

Strand: Direct

Name: paaN [H]

Synonym: BTH_I2900

Alternate gene names: 83718561

Gene position: 3334776-3336482 (Clockwise)

Preceding gene: 83719887

Following gene: 83719929

Centisome position: 87.55

GC content: 65.55

Gene sequence:

>1707_bases
ATGACCCATCCTCTGTTCACGAAGCATGAAGACACGTTGAAGCACGCGCTCTCCACGATCGAAACGCGCGGCTACTGGAG
CCCGTTCGCCGAGATGCCGAGCCCCAAAGTGTACGGGGAAAGCGCCAACGCAGACGGCGAAGCAGCATTCAAAGCCCAAC
TCTACAAACCCTTCGAACTCGATCAGCCCGCCTCTGGCGGAACGGTCGGCGCCGAGCGCTCGCCGTACGGATTTGCACTC
GGCATCCGCTACCCGAAATCTTCGCCCGACGAGTTGATCGCCGCTGCCGCCCAGGCACAGACCGCATGGCGCAAGGCCGG
ACCGTCCGCATGGGTCGGTGTGAGCCTTGAAATCCTCGCCCGGCTGAATCGCGCGAGCTTCGAAATCGCATACAGCGTGA
TGCACACCACCGGACAGGCGTTCATGATGGCTTTCCAGGCGGGCGGGCCGCATGCGCAGGACCGCGCGCTTGAAGCCGTC
GCCTACGCGTGGCACGAACTGCAGCGCATCCCCGCCGACGCCCATTGGGAAAAGCCGCAGGGCAAGAATCCGCCGCTCGC
GATGCACAAGCGCTACACGGTCGTGCCGCGCGGCACGGGGCTCGTGCTCGGTTGCTGCACGTTCCCGACCTGGAACGGCT
ATCCGGGCCTGTTTGCCGATCTGGCAACCGGCAACGCGGTCATCGTCAAGCCGCATCCCGGCGCGATCCTGCCACTCGCG
ATCACCGTGCGCATCGCGCGCGCCGTGCTGCGTGAAGCGGGCTTCGATCCGAACGTCGTCACACTGCTCGCGACCGAAGG
GAGCGACGGCGCGCTCGTCCAAGAGCTGGCGCTCCGCCCGGAGATCAAGCTGATCGACTTCACCGGCAGCTCGCAAAACG
GCAACTGGCTCGAACGCAACGCGCACCAGGCACAGGTGTATACGGAGAAGGCGGGCGTCAACCAGATCGTGATCGATTCC
ATCGACGATCTGAAAGCCGCCGTCAAGAACATCGCGTTCTCGCTCGCGCTCTACTCCGGCCAGATGTGCACCGCGCCGCA
AAACATCTATGTTCCGCGCGACGGCATCCGCACCGCGGAAGGGCACGTCAGTTTCGACGACGTTGCACTGGCAATCGCCG
GCGCCGTGCAGAAGCTGACGGGCGACCCGGCGCGCTCGGTCGAGCTCATCGGCGCGCTCCAGAACGAAGGCATCGCGGCC
CGCATCGACGGCGCGCGCAAACTCGGTCGCGTGCTCGCCGACAGTCAGGCGCTCGAGCATCCGGCATTCAAGGACGCACG
CGTGCGTACGCCGCTCGTGGTGCAGCTCGACGTCGCGGATCGCGCGAAGTACACGCAGGAGTGGTTTGGTCCGATCTCGT
TCGTCATCGCGACCGACTCGACTGCGCAATCGCTCGATCTCGCCGGCTCGATCGCGGCCGAGCACGGCGCGCTGACGCTG
TCCGTCTATAGCACGGACGATGCCGTCGTCGAAGCGGCGCACGATGCGGCGATACGAGGCGGCGTCGCGCTGTCGATCAA
TCTGACGGGTGGCGTGTTCGTCAATCAGTCGGCGGCGTTCTCCGACTTTCACGGCACGGGCGCCAATCCGGCCGCGAACG
CGTCGCTCGCCGATGCAGCGTTCGTCGCGAATCGCTTCCGCGTCGTACAGAGCCGGCACCATGTTGCGCCGAAGGCCGTT
CCCGCGGAAGCTGGCCAAACGGCATAA

Upstream 100 bases:

>100_bases
TGCCGCACACGTACGGACGATTTGATGCTAACATTTTCCGACCAACCGGTCGGTTAATTAATGACCGCCACCTTTCTCAA
CGTTCACCACGCCTGCCGCC

Downstream 100 bases:

>100_bases
CCCGTTCGGCCGAGCTGCCGATCGCGCGATCGTTCACTACCATGAATGAACCCGCCCGCTCGCGGGTTCACCCTTGCCGG
AACTCGACATGACCAAAGCA

Product: phenylacetic acid degradation protein paaN

Products: NA

Alternate protein names: P5C dehydrogenase 1 [H]

Number of amino acids: Translated: 568; Mature: 567

Protein sequence:

>568_residues
MTHPLFTKHEDTLKHALSTIETRGYWSPFAEMPSPKVYGESANADGEAAFKAQLYKPFELDQPASGGTVGAERSPYGFAL
GIRYPKSSPDELIAAAAQAQTAWRKAGPSAWVGVSLEILARLNRASFEIAYSVMHTTGQAFMMAFQAGGPHAQDRALEAV
AYAWHELQRIPADAHWEKPQGKNPPLAMHKRYTVVPRGTGLVLGCCTFPTWNGYPGLFADLATGNAVIVKPHPGAILPLA
ITVRIARAVLREAGFDPNVVTLLATEGSDGALVQELALRPEIKLIDFTGSSQNGNWLERNAHQAQVYTEKAGVNQIVIDS
IDDLKAAVKNIAFSLALYSGQMCTAPQNIYVPRDGIRTAEGHVSFDDVALAIAGAVQKLTGDPARSVELIGALQNEGIAA
RIDGARKLGRVLADSQALEHPAFKDARVRTPLVVQLDVADRAKYTQEWFGPISFVIATDSTAQSLDLAGSIAAEHGALTL
SVYSTDDAVVEAAHDAAIRGGVALSINLTGGVFVNQSAAFSDFHGTGANPAANASLADAAFVANRFRVVQSRHHVAPKAV
PAEAGQTA

Sequences:

>Translated_568_residues
MTHPLFTKHEDTLKHALSTIETRGYWSPFAEMPSPKVYGESANADGEAAFKAQLYKPFELDQPASGGTVGAERSPYGFAL
GIRYPKSSPDELIAAAAQAQTAWRKAGPSAWVGVSLEILARLNRASFEIAYSVMHTTGQAFMMAFQAGGPHAQDRALEAV
AYAWHELQRIPADAHWEKPQGKNPPLAMHKRYTVVPRGTGLVLGCCTFPTWNGYPGLFADLATGNAVIVKPHPGAILPLA
ITVRIARAVLREAGFDPNVVTLLATEGSDGALVQELALRPEIKLIDFTGSSQNGNWLERNAHQAQVYTEKAGVNQIVIDS
IDDLKAAVKNIAFSLALYSGQMCTAPQNIYVPRDGIRTAEGHVSFDDVALAIAGAVQKLTGDPARSVELIGALQNEGIAA
RIDGARKLGRVLADSQALEHPAFKDARVRTPLVVQLDVADRAKYTQEWFGPISFVIATDSTAQSLDLAGSIAAEHGALTL
SVYSTDDAVVEAAHDAAIRGGVALSINLTGGVFVNQSAAFSDFHGTGANPAANASLADAAFVANRFRVVQSRHHVAPKAV
PAEAGQTA
>Mature_567_residues
THPLFTKHEDTLKHALSTIETRGYWSPFAEMPSPKVYGESANADGEAAFKAQLYKPFELDQPASGGTVGAERSPYGFALG
IRYPKSSPDELIAAAAQAQTAWRKAGPSAWVGVSLEILARLNRASFEIAYSVMHTTGQAFMMAFQAGGPHAQDRALEAVA
YAWHELQRIPADAHWEKPQGKNPPLAMHKRYTVVPRGTGLVLGCCTFPTWNGYPGLFADLATGNAVIVKPHPGAILPLAI
TVRIARAVLREAGFDPNVVTLLATEGSDGALVQELALRPEIKLIDFTGSSQNGNWLERNAHQAQVYTEKAGVNQIVIDSI
DDLKAAVKNIAFSLALYSGQMCTAPQNIYVPRDGIRTAEGHVSFDDVALAIAGAVQKLTGDPARSVELIGALQNEGIAAR
IDGARKLGRVLADSQALEHPAFKDARVRTPLVVQLDVADRAKYTQEWFGPISFVIATDSTAQSLDLAGSIAAEHGALTLS
VYSTDDAVVEAAHDAAIRGGVALSINLTGGVFVNQSAAFSDFHGTGANPAANASLADAAFVANRFRVVQSRHHVAPKAVP
AEAGQTA

Specific function: Oxidizes Proline To Glutamate For Use As A Carbon And Nitrogen Source And Also Function As A Transcriptional Repressor Of The Put Operon. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family. RocA subfamily [H]

Homologues:

Organism=Homo sapiens, GI115387104, Length=287, Percent_Identity=25.4355400696864, Blast_Score=69, Evalue=9e-12,
Organism=Escherichia coli, GI1787250, Length=368, Percent_Identity=26.3586956521739, Blast_Score=69, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6321828, Length=530, Percent_Identity=23.0188679245283, Blast_Score=68, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6320917, Length=158, Percent_Identity=34.1772151898734, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005932 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.5.1.12 [H]

Molecular weight: Translated: 60366; Mature: 60234

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHPLFTKHEDTLKHALSTIETRGYWSPFAEMPSPKVYGESANADGEAAFKAQLYKPFEL
CCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHCCCCCEECCCCCCCCCEEHHHHCCCCCCC
DQPASGGTVGAERSPYGFALGIRYPKSSPDELIAAAAQAQTAWRKAGPSAWVGVSLEILA
CCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHH
RLNRASFEIAYSVMHTTGQAFMMAFQAGGPHAQDRALEAVAYAWHELQRIPADAHWEKPQ
HHCCCHHHEEHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GKNPPLAMHKRYTVVPRGTGLVLGCCTFPTWNGYPGLFADLATGNAVIVKPHPGAILPLA
CCCCCEEECCEEEEEECCCCEEEEEECCCCCCCCCCHHHHHCCCCEEEECCCCCCEEHHH
ITVRIARAVLREAGFDPNVVTLLATEGSDGALVQELALRPEIKLIDFTGSSQNGNWLERN
HHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHCCCCEEEEEEECCCCCCCHHHCC
AHQAQVYTEKAGVNQIVIDSIDDLKAAVKNIAFSLALYSGQMCTAPQNIYVPRDGIRTAE
CCHHEEEEHHCCCCEEEECCHHHHHHHHHHHHHHEEEECCCEECCCCCEEECCCCCCCCC
GHVSFDDVALAIAGAVQKLTGDPARSVELIGALQNEGIAARIDGARKLGRVLADSQALEH
CCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEEECCHHHHHHHHHCCHHHCC
PAFKDARVRTPLVVQLDVADRAKYTQEWFGPISFVIATDSTAQSLDLAGSIAAEHGALTL
CCCCCCCCCCCEEEEEECCHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCCCCEEEE
SVYSTDDAVVEAAHDAAIRGGVALSINLTGGVFVNQSAAFSDFHGTGANPAANASLADAA
EEEECCHHHHHHHHHHHHCCCEEEEEEECCCEEEECCCCCCCCCCCCCCCCCCCCHHHHH
FVANRFRVVQSRHHVAPKAVPAEAGQTA
HHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
THPLFTKHEDTLKHALSTIETRGYWSPFAEMPSPKVYGESANADGEAAFKAQLYKPFEL
CCCCCCCCHHHHHHHHHHHHCCCCCCCHHHCCCCCEECCCCCCCCCEEHHHHCCCCCCC
DQPASGGTVGAERSPYGFALGIRYPKSSPDELIAAAAQAQTAWRKAGPSAWVGVSLEILA
CCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHH
RLNRASFEIAYSVMHTTGQAFMMAFQAGGPHAQDRALEAVAYAWHELQRIPADAHWEKPQ
HHCCCHHHEEHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GKNPPLAMHKRYTVVPRGTGLVLGCCTFPTWNGYPGLFADLATGNAVIVKPHPGAILPLA
CCCCCEEECCEEEEEECCCCEEEEEECCCCCCCCCCHHHHHCCCCEEEECCCCCCEEHHH
ITVRIARAVLREAGFDPNVVTLLATEGSDGALVQELALRPEIKLIDFTGSSQNGNWLERN
HHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHCCCCEEEEEEECCCCCCCHHHCC
AHQAQVYTEKAGVNQIVIDSIDDLKAAVKNIAFSLALYSGQMCTAPQNIYVPRDGIRTAE
CCHHEEEEHHCCCCEEEECCHHHHHHHHHHHHHHEEEECCCEECCCCCEEECCCCCCCCC
GHVSFDDVALAIAGAVQKLTGDPARSVELIGALQNEGIAARIDGARKLGRVLADSQALEH
CCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEEECCHHHHHHHHHCCHHHCC
PAFKDARVRTPLVVQLDVADRAKYTQEWFGPISFVIATDSTAQSLDLAGSIAAEHGALTL
CCCCCCCCCCCEEEEEECCHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCCCCEEEE
SVYSTDDAVVEAAHDAAIRGGVALSINLTGGVFVNQSAAFSDFHGTGANPAANASLADAA
EEEECCHHHHHHHHHHHHCCCEEEEEEECCCEEEECCCCCCCCCCCCCCCCCCCCHHHHH
FVANRFRVVQSRHHVAPKAVPAEAGQTA
HHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]