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The map label for this gene is comA [H]

Identifier: 83718537

GI number: 83718537

Start: 2136274

End: 2138811

Strand: Direct

Name: comA [H]

Synonym: BTH_I1890

Alternate gene names: 83718537

Gene position: 2136274-2138811 (Clockwise)

Preceding gene: 83721298

Following gene: 83719013

Centisome position: 56.08

GC content: 75.26

Gene sequence:

>2538_bases
ATGCGGGCGAGGTGCGGCGCGTTCGCGCTCGGCGTCGTCGCGCTGCAGCAGCAGGCGGCGTTGCCGGGCGCGGCGGCATG
GGCGGGCGGCGCGCTCGCGTTCGGCTTGTGCGTGTGGCTCGCGCTCGCGTGGCGCGACGGCGTGCGTGCGCGCACGCGAT
CGATCGGGTTCTGCGCATGCTGTTGCGCGGCCGCGCTCGCGGGCTTCGGCTACGCGGCGGCGCGCGCGCAGTGGCGGCTT
GCCGATGCGCTGCCCGCGCAGTGGGAGGGGCGCGACATCGTCGTGACGGGCGCCGTGCGCGGCTTGCCGTCGCGCGACGC
GAACGGCACGCGTTTCCTGTTCGACGTCGATGAAAACGACGCGCGCATCGCGCGGTTTCCGGCGACGCTGTCGCTTGCGT
GGTACACGTTCGGCCGCTCGGCCGCGTCGCCGCCCGAGCTCGTGCCGGGCGACCGATGGCGGCTGCGCGTGCGTCTGAAA
CGCCCGCACGGCAATGCGAATTTCGGGGTGCGCGATGCGGAAGCGGCATGGCTCGCGCGCGGCATCCGGGCGCTCGGCTA
CGTATCGGCGGCGCACGATGCGCAACGGCTCGCGGGGCGCGCGTCCGGCGTCGCGGCGATGGTCGACCGGTTGCGTGCGC
GCCTGCGCGGGCGCATCGCCGATGCGCTCGGCGACGCCGCGCATCGCGGGATCGTCGTCGCGCTCGCGATCGGCGCGCAG
GACGACATCGTCGACGGCGACCGGCGCATCCTGCGCGATACCGGCACGAGCCACCTCGTCGCGATTTCCGGGCTGCACGT
CGGGATGGTCGGCGGCCTGTGCGCGTGGCTCGCAGGCGGGTTCTGGCGGCGCTCGGGCTACGTCGGGCGCAACTGGCCGC
TTGTCGTGCCCGCGCAGAAGGTCGCGGCGCTCGGCGCGATCGTCGGCGGCGCCGGCTATGCGGCGCTCGCGGGCTTCAAC
GTGCCCGCGCAGCGCGCGTGGTGGATGCTCGCCGCCGCGGGCGTCGCATATCTGAGCGGGCGCTCGCTCGCGCCGTCTTC
GGTGCTGGCGGCGGCGCTCGGCTGCGTGCTGATCGTCGATCCGTGGGCAGTGACGTCGCCGGGGTTCTGGCTGTCGTTCT
GCGCGGTCGCTGCGATCCTGTTCGCGTCGTCGGGGCGAAGCGCCGCGCGCGAAGCGCGCGACCTCGACGAGGCGCGCGGC
TCGATCGACGGCGCATGTCGCGAACGCGCGTCGCCGCCGGCGTGTCCCGCGCGGTGGCGTGCCGCGTGTGCGCGGGCACG
GATGAGGGCGAGGCGCGCGATCGGGCGGCTCGTTCGGCGCGTGCGCGATGCCGCGCGGGCGCAGTTCGCGGTGACGATCG
CGCTCGCGCCGCTCACCGCGCTGTGGTTCGCGCAGATTCCGCTCACCGGCCCGCTCGCAAATGCGTTCGCGATTCCGTGG
GTCGGCTCGCTCGTCACGCCGATCGTGCTCGCGGGCGTCGTGCTGCCCGCGCCGCTCGACGCACCGGCGTACGTGCTCGG
CGAAGCGCTCGTCGCGGCGCTGATGCGGTTCCTCGAAGCGGCAGCCGGCGCGGGGCGCACGGTCTGGATGCTGCCGGTGC
CGGGCGGCTTCGCGCTCGCCACGGCGGCGGCGGGTGTCGTGTGGGCGCTGACGCCGCGCGGCTGGCCGCTGCGCGGTGCG
GCGCCGCTCGCGTGGCTGCCGCTTGTCGTGCCGGCTCCGCTCGCCCTGCCCGACGGCACGTTCCGGTTGACGGCGCTCGA
CGTCGGGCAGGGCTCGGCGGTGTTGATCGAAACCGCGCGGCATGCGCTGCTGTTCGACGCGGGCCCGGGGCCGGAGGCGT
CGAATGCGGGCGAGCGGGTCGTCGTGCCGTTCTTGCGCGCGCGGGGCGTGCGCATGCTCGACACGCTCGTCGTGAGCCAC
GCGGATTCGGACCACGCGGGCGGCGCGCCCGCCGTCCTCGAAGCGATCACGGTCGCGCAGGTGACGGGCGGGCTGCCGCC
GTCGAACCGCCTGTGGCGCGTCGCGCACGCAGCCGGCGTGGCCGACGCGCTGCCGTGCGCGGCGGGGCAGCGCTGGCGCT
GGGACGGCGTCGAGTTCGCGACGCTCTGGCCCGCCGGCGGGCCGCGCGCGGGCGGCGCGACGAACGCTCAGTCGTGCGTG
CTGCGCGTGTCGGCGGGCGAGCGTGCGGCGCTCCTGACGGGCGATGTCGACGCACGCTCCGAGCGCGCGCTCGTCGCCGG
GGCGCGCCGAGCGCTCGCGGCGCAGGTGCTCGTCGTCCCGCACCATGGCAGCCGCACGTCGTCGACCGAGCCTTTCCTCG
ATTCGGTCGAGCCGCGCATTGCAATATTTCAGGTAGGCTACGCCAACAGGTTTCACCATCCGCATCCGACCGTCTGGGCG
CGCTATGCCGGGCGCGGCATCGAGTTGCCGCGTACCGACCGCGACGGCGCCGTGCGCGTCGACATGACGTCGAGCGGCGC
GCTCCCCGCGCCGGTACGGTATCGGGACGCGCACCGGCGCTACTGGATGGACCGTTGA

Upstream 100 bases:

>100_bases
CTAACGCGCTCGCCGCGCTGCCGCGACTCGCGCTTTCGTCCGCATAATCGATTCGTGACGGACACGCGTCGCTCGGGCGG
CGCGAATAGACGGAGGCGCG

Downstream 100 bases:

>100_bases
CGCGGTGCGGAGGCTACGACAGGGAGACAGCGTCGTTTGAAGGACATCATCCATTTCTCGCATGCGAACGGCTTTCCGGC
GTCCACGTATCGGACGATCT

Product: DNA internalization-related competence protein ComEC/Rec2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 845; Mature: 845

Protein sequence:

>845_residues
MRARCGAFALGVVALQQQAALPGAAAWAGGALAFGLCVWLALAWRDGVRARTRSIGFCACCCAAALAGFGYAAARAQWRL
ADALPAQWEGRDIVVTGAVRGLPSRDANGTRFLFDVDENDARIARFPATLSLAWYTFGRSAASPPELVPGDRWRLRVRLK
RPHGNANFGVRDAEAAWLARGIRALGYVSAAHDAQRLAGRASGVAAMVDRLRARLRGRIADALGDAAHRGIVVALAIGAQ
DDIVDGDRRILRDTGTSHLVAISGLHVGMVGGLCAWLAGGFWRRSGYVGRNWPLVVPAQKVAALGAIVGGAGYAALAGFN
VPAQRAWWMLAAAGVAYLSGRSLAPSSVLAAALGCVLIVDPWAVTSPGFWLSFCAVAAILFASSGRSAAREARDLDEARG
SIDGACRERASPPACPARWRAACARARMRARRAIGRLVRRVRDAARAQFAVTIALAPLTALWFAQIPLTGPLANAFAIPW
VGSLVTPIVLAGVVLPAPLDAPAYVLGEALVAALMRFLEAAAGAGRTVWMLPVPGGFALATAAAGVVWALTPRGWPLRGA
APLAWLPLVVPAPLALPDGTFRLTALDVGQGSAVLIETARHALLFDAGPGPEASNAGERVVVPFLRARGVRMLDTLVVSH
ADSDHAGGAPAVLEAITVAQVTGGLPPSNRLWRVAHAAGVADALPCAAGQRWRWDGVEFATLWPAGGPRAGGATNAQSCV
LRVSAGERAALLTGDVDARSERALVAGARRALAAQVLVVPHHGSRTSSTEPFLDSVEPRIAIFQVGYANRFHHPHPTVWA
RYAGRGIELPRTDRDGAVRVDMTSSGALPAPVRYRDAHRRYWMDR

Sequences:

>Translated_845_residues
MRARCGAFALGVVALQQQAALPGAAAWAGGALAFGLCVWLALAWRDGVRARTRSIGFCACCCAAALAGFGYAAARAQWRL
ADALPAQWEGRDIVVTGAVRGLPSRDANGTRFLFDVDENDARIARFPATLSLAWYTFGRSAASPPELVPGDRWRLRVRLK
RPHGNANFGVRDAEAAWLARGIRALGYVSAAHDAQRLAGRASGVAAMVDRLRARLRGRIADALGDAAHRGIVVALAIGAQ
DDIVDGDRRILRDTGTSHLVAISGLHVGMVGGLCAWLAGGFWRRSGYVGRNWPLVVPAQKVAALGAIVGGAGYAALAGFN
VPAQRAWWMLAAAGVAYLSGRSLAPSSVLAAALGCVLIVDPWAVTSPGFWLSFCAVAAILFASSGRSAAREARDLDEARG
SIDGACRERASPPACPARWRAACARARMRARRAIGRLVRRVRDAARAQFAVTIALAPLTALWFAQIPLTGPLANAFAIPW
VGSLVTPIVLAGVVLPAPLDAPAYVLGEALVAALMRFLEAAAGAGRTVWMLPVPGGFALATAAAGVVWALTPRGWPLRGA
APLAWLPLVVPAPLALPDGTFRLTALDVGQGSAVLIETARHALLFDAGPGPEASNAGERVVVPFLRARGVRMLDTLVVSH
ADSDHAGGAPAVLEAITVAQVTGGLPPSNRLWRVAHAAGVADALPCAAGQRWRWDGVEFATLWPAGGPRAGGATNAQSCV
LRVSAGERAALLTGDVDARSERALVAGARRALAAQVLVVPHHGSRTSSTEPFLDSVEPRIAIFQVGYANRFHHPHPTVWA
RYAGRGIELPRTDRDGAVRVDMTSSGALPAPVRYRDAHRRYWMDR
>Mature_845_residues
MRARCGAFALGVVALQQQAALPGAAAWAGGALAFGLCVWLALAWRDGVRARTRSIGFCACCCAAALAGFGYAAARAQWRL
ADALPAQWEGRDIVVTGAVRGLPSRDANGTRFLFDVDENDARIARFPATLSLAWYTFGRSAASPPELVPGDRWRLRVRLK
RPHGNANFGVRDAEAAWLARGIRALGYVSAAHDAQRLAGRASGVAAMVDRLRARLRGRIADALGDAAHRGIVVALAIGAQ
DDIVDGDRRILRDTGTSHLVAISGLHVGMVGGLCAWLAGGFWRRSGYVGRNWPLVVPAQKVAALGAIVGGAGYAALAGFN
VPAQRAWWMLAAAGVAYLSGRSLAPSSVLAAALGCVLIVDPWAVTSPGFWLSFCAVAAILFASSGRSAAREARDLDEARG
SIDGACRERASPPACPARWRAACARARMRARRAIGRLVRRVRDAARAQFAVTIALAPLTALWFAQIPLTGPLANAFAIPW
VGSLVTPIVLAGVVLPAPLDAPAYVLGEALVAALMRFLEAAAGAGRTVWMLPVPGGFALATAAAGVVWALTPRGWPLRGA
APLAWLPLVVPAPLALPDGTFRLTALDVGQGSAVLIETARHALLFDAGPGPEASNAGERVVVPFLRARGVRMLDTLVVSH
ADSDHAGGAPAVLEAITVAQVTGGLPPSNRLWRVAHAAGVADALPCAAGQRWRWDGVEFATLWPAGGPRAGGATNAQSCV
LRVSAGERAALLTGDVDARSERALVAGARRALAAQVLVVPHHGSRTSSTEPFLDSVEPRIAIFQVGYANRFHHPHPTVWA
RYAGRGIELPRTDRDGAVRVDMTSSGALPAPVRYRDAHRRYWMDR

Specific function: Essential for natural transformation. Could be a transporter involved in DNA uptake [H]

COG id: COG0658

COG function: function code R; Predicted membrane metal-binding protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis ComEC, H.influenzae REC2, and E.coli YcaI [H]

Homologues:

Organism=Escherichia coli, GI87081801, Length=718, Percent_Identity=27.2980501392758, Blast_Score=208, Evalue=1e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR004477
- InterPro:   IPR004797 [H]

Pfam domain/function: PF03772 Competence; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 88789; Mature: 88789

Theoretical pI: Translated: 11.42; Mature: 11.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRARCGAFALGVVALQQQAALPGAAAWAGGALAFGLCVWLALAWRDGVRARTRSIGFCAC
CCCCCHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHH
CCAAALAGFGYAAARAQWRLADALPAQWEGRDIVVTGAVRGLPSRDANGTRFLFDVDEND
HHHHHHHHCCHHHHHHHEHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCEEEEEEECCCC
ARIARFPATLSLAWYTFGRSAASPPELVPGDRWRLRVRLKRPHGNANFGVRDAEAAWLAR
CEEEECCCEEEEEEEECCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHH
GIRALGYVSAAHDAQRLAGRASGVAAMVDRLRARLRGRIADALGDAAHRGIVVALAIGAQ
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCC
DDIVDGDRRILRDTGTSHLVAISGLHVGMVGGLCAWLAGGFWRRSGYVGRNWPLVVPAQK
CCCCCCCHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHCCHHHCCCCCCCCCCEEECHHH
VAALGAIVGGAGYAALAGFNVPAQRAWWMLAAAGVAYLSGRSLAPSSVLAAALGCVLIVD
HHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCEEEEEC
PWAVTSPGFWLSFCAVAAILFASSGRSAAREARDLDEARGSIDGACRERASPPACPARWR
CCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCHHHH
AACARARMRARRAIGRLVRRVRDAARAQFAVTIALAPLTALWFAQIPLTGPLANAFAIPW
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEHHHHHHHHHHHCCCCCCCHHHHHHHH
VGSLVTPIVLAGVVLPAPLDAPAYVLGEALVAALMRFLEAAAGAGRTVWMLPVPGGFALA
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHH
TAAAGVVWALTPRGWPLRGAAPLAWLPLVVPAPLALPDGTFRLTALDVGQGSAVLIETAR
HHHCCEEEEECCCCCCCCCCCCHHHHHHHCCCCCCCCCCCEEEEEEECCCCCEEEEEECC
HALLFDAGPGPEASNAGERVVVPFLRARGVRMLDTLVVSHADSDHAGGAPAVLEAITVAQ
CEEEEECCCCCCCCCCCCEEEEEHHHHCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
VTGGLPPSNRLWRVAHAAGVADALPCAAGQRWRWDGVEFATLWPAGGPRAGGATNAQSCV
HHCCCCCCCCCEEHHHHHCCHHHCCCCCCCCEEECCEEEEEECCCCCCCCCCCCCCCCEE
LRVSAGERAALLTGDVDARSERALVAGARRALAAQVLVVPHHGSRTSSTEPFLDSVEPRI
EEECCCCCEEEEECCCCCCCCHHHHHHHHHHHEEEEEEEECCCCCCCCCCCHHHCCCCEE
AIFQVGYANRFHHPHPTVWARYAGRGIELPRTDRDGAVRVDMTSSGALPAPVRYRDAHRR
EEEEECCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHH
YWMDR
HCCCC
>Mature Secondary Structure
MRARCGAFALGVVALQQQAALPGAAAWAGGALAFGLCVWLALAWRDGVRARTRSIGFCAC
CCCCCHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHH
CCAAALAGFGYAAARAQWRLADALPAQWEGRDIVVTGAVRGLPSRDANGTRFLFDVDEND
HHHHHHHHCCHHHHHHHEHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCEEEEEEECCCC
ARIARFPATLSLAWYTFGRSAASPPELVPGDRWRLRVRLKRPHGNANFGVRDAEAAWLAR
CEEEECCCEEEEEEEECCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHH
GIRALGYVSAAHDAQRLAGRASGVAAMVDRLRARLRGRIADALGDAAHRGIVVALAIGAQ
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCC
DDIVDGDRRILRDTGTSHLVAISGLHVGMVGGLCAWLAGGFWRRSGYVGRNWPLVVPAQK
CCCCCCCHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHCCHHHCCCCCCCCCCEEECHHH
VAALGAIVGGAGYAALAGFNVPAQRAWWMLAAAGVAYLSGRSLAPSSVLAAALGCVLIVD
HHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCEEEEEC
PWAVTSPGFWLSFCAVAAILFASSGRSAAREARDLDEARGSIDGACRERASPPACPARWR
CCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCHHHH
AACARARMRARRAIGRLVRRVRDAARAQFAVTIALAPLTALWFAQIPLTGPLANAFAIPW
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEHHHHHHHHHHHCCCCCCCHHHHHHHH
VGSLVTPIVLAGVVLPAPLDAPAYVLGEALVAALMRFLEAAAGAGRTVWMLPVPGGFALA
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHH
TAAAGVVWALTPRGWPLRGAAPLAWLPLVVPAPLALPDGTFRLTALDVGQGSAVLIETAR
HHHCCEEEEECCCCCCCCCCCCHHHHHHHCCCCCCCCCCCEEEEEEECCCCCEEEEEECC
HALLFDAGPGPEASNAGERVVVPFLRARGVRMLDTLVVSHADSDHAGGAPAVLEAITVAQ
CEEEEECCCCCCCCCCCCEEEEEHHHHCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
VTGGLPPSNRLWRVAHAAGVADALPCAAGQRWRWDGVEFATLWPAGGPRAGGATNAQSCV
HHCCCCCCCCCEEHHHHHCCHHHCCCCCCCCEEECCEEEEEECCCCCCCCCCCCCCCCEE
LRVSAGERAALLTGDVDARSERALVAGARRALAAQVLVVPHHGSRTSSTEPFLDSVEPRI
EEECCCCCEEEEECCCCCCCCHHHHHHHHHHHEEEEEEEECCCCCCCCCCCHHHCCCCEE
AIFQVGYANRFHHPHPTVWARYAGRGIELPRTDRDGAVRVDMTSSGALPAPVRYRDAHRR
EEEEECCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHH
YWMDR
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934834; 8830266 [H]