Click here to switch to the map view.

The map label for this gene is cynX [H]

Identifier: 83718476

GI number: 83718476

Start: 2719609

End: 2720781

Strand: Direct

Name: cynX [H]

Synonym: BTH_I2392

Alternate gene names: 83718476

Gene position: 2719609-2720781 (Clockwise)

Preceding gene: 83719580

Following gene: 83720951

Centisome position: 71.4

GC content: 74.85

Gene sequence:

>1173_bases
ATGCCCATGCTTAATTCTCCTGCATGGCGGCTTGCCGCCATCGTGCTCGTCGGCCTCAATCTGCGTCCTGTGCTCGCGTC
GGTCGGGCCGCTTCTCGACGCGATCCAGCGCGCGACCGGCTTGTCCGACAGCGCGGCGAGCCTGCTGACGACCTTGCCGA
TCCTGCTGATGGGTGCGGGCGCGCTCGCCGCGCCGTGGCTCGCTCGCCGCGCCGGCGTGCGCGCGGGCGTCTGGCTCGGC
GTCGCGCTGATCGGGCTTGCGTGCGCGGTGCGCGGCGCGGCGAGCGCGCCCGCGGTGCTGCTCGCGTCCGCGCTGTGCGC
GGGGCTCGGCATCGCGGCCGTGCAGGCGCTGCTGCCCGCGTTCATCAAGGCGGAGTTCGCCGCGCGCGCGGGCGGCGTGA
TGGGTTTCTATTCGACATCGATCATGGGCGGCGCGGTATTCGCGAGCGTCGCGACGCCGTTCGCCGCGCGCGCGATCGGC
TGGACGTCCGCGCTCGCCGGCTGGGCGCTGCCCGCCGTCGCGGCCGCGCTGCTGTGGCCGCTCGCGACCGGCGCGACAAA
GCGCGCCGTGCACGCGCCACCGGCCGCGCGCCGCGCGCACGGCGCGCGCGCGTGGCTGCTCGCCGCGTTCTTCGGCCTCG
GCACGGGCGCCTATACGCTCGTGCTCGCGTGGCTGCCGCCCTATTACATGTCGCTCGGCTGGTCGCCGCAAGCGGCGGGC
GGCCTGCTCGGCGGCGTGACGCTCGCCGAGGTCGCCTCGGGGCTCACCGTGTCGGCGTTCATCGATCGGCTGCCCGACCG
CCGTCCCGCGCTGTTCGCGGCGATCGCGTCGCTGTTCGTCGGCCTGATCGCGCTGATCGCCGCGCCGCTCGGCTTCGCGC
TGCCCGCGTCGCTGCTGCTCGGCCTCGGCATCGGCGCGCTGTTTCCGCTGTCGCTGATCGTCGCGCTCGACCATGCGACG
AGCGCGGCCGACGCCGGCACGCTTACCGGCTTCGTCCAGGGCGTCGGCTATCTGGTCGCGGGCCTGTTTCCGTTCGCGGC
GGGCGTGATCCGGCAGAACGTCGCCGACCTGTCGCCGGCCTGGGGCTTCATGGCCGCGGTGTGCGTCGTGATGGCGGCAA
TGGCCGCGCGCCTCGCGCCGCCGCGGCTCACCGTCGCGCGAAGCGGCGCATGA

Upstream 100 bases:

>100_bases
CGTCCAAGTTATCTTGACGTAGAGACATGTCGAATCTATCTTGATGTCGAGACAATTATACGCAACGCGCGCCCGGCAGC
CGTCCGGACGCGCCGCATCC

Downstream 100 bases:

>100_bases
GCGGCGGCGCTCGCGTGCCGCCCGGTCCGGAACTCGCTTCGAGCGTCGAGGTCCCTATGGAATCTCTTCATCTGAACGCG
CCGACGCGATCCAAGGACCT

Product: major facilitator family transporter

Products: Proton [Cytoplasm]; Cyanate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 389

Protein sequence:

>390_residues
MPMLNSPAWRLAAIVLVGLNLRPVLASVGPLLDAIQRATGLSDSAASLLTTLPILLMGAGALAAPWLARRAGVRAGVWLG
VALIGLACAVRGAASAPAVLLASALCAGLGIAAVQALLPAFIKAEFAARAGGVMGFYSTSIMGGAVFASVATPFAARAIG
WTSALAGWALPAVAAALLWPLATGATKRAVHAPPAARRAHGARAWLLAAFFGLGTGAYTLVLAWLPPYYMSLGWSPQAAG
GLLGGVTLAEVASGLTVSAFIDRLPDRRPALFAAIASLFVGLIALIAAPLGFALPASLLLGLGIGALFPLSLIVALDHAT
SAADAGTLTGFVQGVGYLVAGLFPFAAGVIRQNVADLSPAWGFMAAVCVVMAAMAARLAPPRLTVARSGA

Sequences:

>Translated_390_residues
MPMLNSPAWRLAAIVLVGLNLRPVLASVGPLLDAIQRATGLSDSAASLLTTLPILLMGAGALAAPWLARRAGVRAGVWLG
VALIGLACAVRGAASAPAVLLASALCAGLGIAAVQALLPAFIKAEFAARAGGVMGFYSTSIMGGAVFASVATPFAARAIG
WTSALAGWALPAVAAALLWPLATGATKRAVHAPPAARRAHGARAWLLAAFFGLGTGAYTLVLAWLPPYYMSLGWSPQAAG
GLLGGVTLAEVASGLTVSAFIDRLPDRRPALFAAIASLFVGLIALIAAPLGFALPASLLLGLGIGALFPLSLIVALDHAT
SAADAGTLTGFVQGVGYLVAGLFPFAAGVIRQNVADLSPAWGFMAAVCVVMAAMAARLAPPRLTVARSGA
>Mature_389_residues
PMLNSPAWRLAAIVLVGLNLRPVLASVGPLLDAIQRATGLSDSAASLLTTLPILLMGAGALAAPWLARRAGVRAGVWLGV
ALIGLACAVRGAASAPAVLLASALCAGLGIAAVQALLPAFIKAEFAARAGGVMGFYSTSIMGGAVFASVATPFAARAIGW
TSALAGWALPAVAAALLWPLATGATKRAVHAPPAARRAHGARAWLLAAFFGLGTGAYTLVLAWLPPYYMSLGWSPQAAGG
LLGGVTLAEVASGLTVSAFIDRLPDRRPALFAAIASLFVGLIALIAAPLGFALPASLLLGLGIGALFPLSLIVALDHATS
AADAGTLTGFVQGVGYLVAGLFPFAAGVIRQNVADLSPAWGFMAAVCVVMAAMAARLAPPRLTVARSGA

Specific function: This protein is part of an active transport system that transports exogenous cyanate into E.coli cells [H]

COG id: COG2807

COG function: function code P; Cyanate permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Cyanate porter (TC 2.A.1.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786536, Length=376, Percent_Identity=38.563829787234, Blast_Score=208, Evalue=4e-55,
Organism=Escherichia coli, GI1788092, Length=353, Percent_Identity=33.1444759206799, Blast_Score=101, Evalue=7e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004747
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 39005; Mature: 38874

Theoretical pI: Translated: 11.63; Mature: 11.63

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMLNSPAWRLAAIVLVGLNLRPVLASVGPLLDAIQRATGLSDSAASLLTTLPILLMGAG
CCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
ALAAPWLARRAGVRAGVWLGVALIGLACAVRGAASAPAVLLASALCAGLGIAAVQALLPA
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FIKAEFAARAGGVMGFYSTSIMGGAVFASVATPFAARAIGWTSALAGWALPAVAAALLWP
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LATGATKRAVHAPPAARRAHGARAWLLAAFFGLGTGAYTLVLAWLPPYYMSLGWSPQAAG
HHCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHCHHHHHCCCCCCHHC
GLLGGVTLAEVASGLTVSAFIDRLPDRRPALFAAIASLFVGLIALIAAPLGFALPASLLL
HHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLGIGALFPLSLIVALDHATSAADAGTLTGFVQGVGYLVAGLFPFAAGVIRQNVADLSPA
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
WGFMAAVCVVMAAMAARLAPPRLTVARSGA
HHHHHHHHHHHHHHHHHCCCCCEECCCCCC
>Mature Secondary Structure 
PMLNSPAWRLAAIVLVGLNLRPVLASVGPLLDAIQRATGLSDSAASLLTTLPILLMGAG
CCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
ALAAPWLARRAGVRAGVWLGVALIGLACAVRGAASAPAVLLASALCAGLGIAAVQALLPA
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FIKAEFAARAGGVMGFYSTSIMGGAVFASVATPFAARAIGWTSALAGWALPAVAAALLWP
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LATGATKRAVHAPPAARRAHGARAWLLAAFFGLGTGAYTLVLAWLPPYYMSLGWSPQAAG
HHCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHCHHHHHCCCCCCHHC
GLLGGVTLAEVASGLTVSAFIDRLPDRRPALFAAIASLFVGLIALIAAPLGFALPASLLL
HHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLGIGALFPLSLIVALDHATSAADAGTLTGFVQGVGYLVAGLFPFAAGVIRQNVADLSPA
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
WGFMAAVCVVMAAMAARLAPPRLTVARSGA
HHHHHHHHHHHHHHHHHCCCCCEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; Cyanate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + Cyanate [Periplasm] = Proton [Cytoplasm] + Cyanate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3049588; 9278503 [H]