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The map label for this gene is tag [H]

Identifier: 83718447

GI number: 83718447

Start: 3639427

End: 3640035

Strand: Direct

Name: tag [H]

Synonym: BTH_I3193

Alternate gene names: 83718447

Gene position: 3639427-3640035 (Clockwise)

Preceding gene: 83721161

Following gene: 83719673

Centisome position: 95.54

GC content: 63.71

Gene sequence:

>609_bases
ATGCCGAAACAGGGACGCTGCAGTTGGGTAAAAACCGAAGCGGACGCTCACTATCACGATACCGAATGGGGCGTGCCGTC
GCACGACGACCGGCATCTATTCGAGATGCTCGTGCTCGAAGGCGCGCAGGCCGGCCTGTCGTGGTCGACGATTTTGAACA
AGCGCGCCGGCTACCGCGCGGCGTTTGCCGATTTCGACGTCGACAAGGTCGCCGGCTTCACGCCAAAGCGGATCGACGAG
CTGGTGCTCGATGCGAGCATCGTGCGCAACCGCGCGAAGATCGAAGCGGCCGTCGCGAACGCGCGCGCGGTCCAGCAGAT
TCGCGCGGAACATGGCTCGCTTGCCGCGTTCCTGTGGTCATTCGTCGATCATGCGCCGCGGCAGAACGCATGGGCGTCAT
ACCGCGAAGCGCCGGCGTCAACCGAGCGTTCGGACGCGCTCAGCAAGGCGCTCAAGCGCTATGGCTGCAAGTTCGTCGGC
TCGACGATCTGCTATGCGCTAATGCAGGCGACGGGCATGGTCAACGATCACGAAAGAACCTGCCCGTGTCATGCGCGCTG
CGCGGCGCTCGGCGAGAAGGCGGTCAAAAAGAGAAAGCCGGCGACGTGA

Upstream 100 bases:

>100_bases
TAACCGCAACGGTTCGCCGCGCCCATCGGCCGAACGGCCAGGCTTGCGCGCCCTCGCCGATCCGTTATGCTGACGCGACC
AGATCGACGGAACTTGCGAG

Downstream 100 bases:

>100_bases
TCTGAAAGTCCTGCTCCGCCGCGGCGATCGGCGTCGCCGCGACGGGCGGCCGAATGCGAATGGCGGCGCTCGGCATGCGC
GCGGCGGCAGGCATTCGCTT

Product: DNA-3-methyladenine glycosidase I

Products: NA

Alternate protein names: 3-methyladenine-DNA glycosylase I, constitutive; TAG I; DNA-3-methyladenine glycosidase I; DNA-3-methyladenine glycosylase I [H]

Number of amino acids: Translated: 202; Mature: 201

Protein sequence:

>202_residues
MPKQGRCSWVKTEADAHYHDTEWGVPSHDDRHLFEMLVLEGAQAGLSWSTILNKRAGYRAAFADFDVDKVAGFTPKRIDE
LVLDASIVRNRAKIEAAVANARAVQQIRAEHGSLAAFLWSFVDHAPRQNAWASYREAPASTERSDALSKALKRYGCKFVG
STICYALMQATGMVNDHERTCPCHARCAALGEKAVKKRKPAT

Sequences:

>Translated_202_residues
MPKQGRCSWVKTEADAHYHDTEWGVPSHDDRHLFEMLVLEGAQAGLSWSTILNKRAGYRAAFADFDVDKVAGFTPKRIDE
LVLDASIVRNRAKIEAAVANARAVQQIRAEHGSLAAFLWSFVDHAPRQNAWASYREAPASTERSDALSKALKRYGCKFVG
STICYALMQATGMVNDHERTCPCHARCAALGEKAVKKRKPAT
>Mature_201_residues
PKQGRCSWVKTEADAHYHDTEWGVPSHDDRHLFEMLVLEGAQAGLSWSTILNKRAGYRAAFADFDVDKVAGFTPKRIDEL
VLDASIVRNRAKIEAAVANARAVQQIRAEHGSLAAFLWSFVDHAPRQNAWASYREAPASTERSDALSKALKRYGCKFVGS
TICYALMQATGMVNDHERTCPCHARCAALGEKAVKKRKPAT

Specific function: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine from the damaged DNA polymer formed by alkylation lesions [H]

COG id: COG2818

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789971, Length=180, Percent_Identity=51.6666666666667, Blast_Score=192, Evalue=1e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005019
- InterPro:   IPR011257
- InterPro:   IPR004597 [H]

Pfam domain/function: PF03352 Adenine_glyco [H]

EC number: =3.2.2.20 [H]

Molecular weight: Translated: 22389; Mature: 22257

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKQGRCSWVKTEADAHYHDTEWGVPSHDDRHLFEMLVLEGAQAGLSWSTILNKRAGYRA
CCCCCCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHH
AFADFDVDKVAGFTPKRIDELVLDASIVRNRAKIEAAVANARAVQQIRAEHGSLAAFLWS
HHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVDHAPRQNAWASYREAPASTERSDALSKALKRYGCKFVGSTICYALMQATGMVNDHERT
HHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCC
CPCHARCAALGEKAVKKRKPAT
CCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PKQGRCSWVKTEADAHYHDTEWGVPSHDDRHLFEMLVLEGAQAGLSWSTILNKRAGYRA
CCCCCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHH
AFADFDVDKVAGFTPKRIDELVLDASIVRNRAKIEAAVANARAVQQIRAEHGSLAAFLWS
HHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVDHAPRQNAWASYREAPASTERSDALSKALKRYGCKFVGSTICYALMQATGMVNDHERT
HHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCC
CPCHARCAALGEKAVKKRKPAT
CCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3536912; 3520491; 8041620; 9278503 [H]