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The map label for this gene is aqpZ [H]

Identifier: 83721161

GI number: 83721161

Start: 3636495

End: 3637259

Strand: Direct

Name: aqpZ [H]

Synonym: BTH_I3190

Alternate gene names: 83721161

Gene position: 3636495-3637259 (Clockwise)

Preceding gene: 83720271

Following gene: 83718447

Centisome position: 95.47

GC content: 67.45

Gene sequence:

>765_bases
ATGCGTCCCTGCTTTTGCGGCGCAATCCGTTATCGATTTTCACGACCGGGAACCACTCCAATGAAATTACCTCAGCGTCT
CGCGGCGGAAGTGTTCGGCACGTTCTGGCTCGTCCTCGGCGGCTGCGGCAGCGCCGTTCTGGCGGCCGCCTTTCCGGGCC
TCGGCATTGGCTTTGCCGGTGTCGCATTGGCATTCGGCCTGACGGTCCTCACGATGGCGTTCGCCATCGGCCACGTCTCG
GGGTGTCACCTGAATCCGGCCGTGAGCGTCGGCCTGACGGTGGCGGGACGCTTCCCGGCCCGCGATCTCGTGCCGTACAT
CGTCGCGCAGGTCATCGGCGCCACGCTCGGCGCGTTCGTGCTGTACCTGATCGCGACCGGCAAGCCGGGCTTCGACGTCG
TCGGCAGCGGCTTCGCGACGAACGGCTATGACGCGCGCTCGCCCGGCCATTACTCGCTCGCGGCCGCGTTCATCTGCGAA
GTCGTGATGACGGGCTTCTTCCTGTTCGTGATCCTCGGCTCGACCGACAAGCGCGCGCCGGCGGGCTTCGCGCCGATCGC
GATCGGTCTGTGCCTCACGCTGATCCATCTGATTTCGATCCCGGTGACGAACACGTCGGTGAACCCGGCGCGCTCGACGG
GCCCGGCGCTCTTCGTCGGCGGCGAGGCGATCGGCCAGCTGTGGCTGTTCTGGGTGGCGCCCATCATCGGCGCGGCGATC
GCGGGCGTCGTGTACCCGCTCGTCGCGGGACGCGACGAAAGCTGA

Upstream 100 bases:

>100_bases
GCCTTATTCTAATAAAAACACCGATCGGCCAATCTCAATTTGACAATCGTTGACCCTTCGGAACCCGTAAGATTTCCTAT
AATCCAGTCGGCATTCGTGG

Downstream 100 bases:

>100_bases
TGACGGCACGGCCGGACTCGCGCCGGCCGCCCGCCCGTCGCCCACGGGGCGACACGACAGAGGAATATGAAAATCGCTGC
GCGCCGGCCGACGGCGACGG

Product: aquaporin Z

Products: H2O [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MRPCFCGAIRYRFSRPGTTPMKLPQRLAAEVFGTFWLVLGGCGSAVLAAAFPGLGIGFAGVALAFGLTVLTMAFAIGHVS
GCHLNPAVSVGLTVAGRFPARDLVPYIVAQVIGATLGAFVLYLIATGKPGFDVVGSGFATNGYDARSPGHYSLAAAFICE
VVMTGFFLFVILGSTDKRAPAGFAPIAIGLCLTLIHLISIPVTNTSVNPARSTGPALFVGGEAIGQLWLFWVAPIIGAAI
AGVVYPLVAGRDES

Sequences:

>Translated_254_residues
MRPCFCGAIRYRFSRPGTTPMKLPQRLAAEVFGTFWLVLGGCGSAVLAAAFPGLGIGFAGVALAFGLTVLTMAFAIGHVS
GCHLNPAVSVGLTVAGRFPARDLVPYIVAQVIGATLGAFVLYLIATGKPGFDVVGSGFATNGYDARSPGHYSLAAAFICE
VVMTGFFLFVILGSTDKRAPAGFAPIAIGLCLTLIHLISIPVTNTSVNPARSTGPALFVGGEAIGQLWLFWVAPIIGAAI
AGVVYPLVAGRDES
>Mature_254_residues
MRPCFCGAIRYRFSRPGTTPMKLPQRLAAEVFGTFWLVLGGCGSAVLAAAFPGLGIGFAGVALAFGLTVLTMAFAIGHVS
GCHLNPAVSVGLTVAGRFPARDLVPYIVAQVIGATLGAFVLYLIATGKPGFDVVGSGFATNGYDARSPGHYSLAAAFICE
VVMTGFFLFVILGSTDKRAPAGFAPIAIGLCLTLIHLISIPVTNTSVNPARSTGPALFVGGEAIGQLWLFWVAPIIGAAI
AGVVYPLVAGRDES

Specific function: Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response

COG id: COG0580

COG function: function code G; Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MIP/aquaporin (TC 1.A.8) family [H]

Homologues:

Organism=Homo sapiens, GI4502181, Length=190, Percent_Identity=36.8421052631579, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI4755125, Length=190, Percent_Identity=37.3684210526316, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI4502183, Length=219, Percent_Identity=35.6164383561644, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI37694062, Length=190, Percent_Identity=34.7368421052632, Blast_Score=105, Evalue=3e-23,
Organism=Homo sapiens, GI4502179, Length=222, Percent_Identity=32.8828828828829, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI6912506, Length=224, Percent_Identity=32.5892857142857, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI86792455, Length=192, Percent_Identity=32.8125, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI157266307, Length=254, Percent_Identity=31.1023622047244, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI4826645, Length=268, Percent_Identity=34.3283582089552, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI45446752, Length=211, Percent_Identity=28.436018957346, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI22538420, Length=247, Percent_Identity=30.3643724696356, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI4502187, Length=243, Percent_Identity=28.8065843621399, Blast_Score=72, Evalue=4e-13,
Organism=Escherichia coli, GI1787101, Length=207, Percent_Identity=70.048309178744, Blast_Score=287, Evalue=5e-79,
Organism=Escherichia coli, GI1790362, Length=255, Percent_Identity=29.8039215686275, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71993722, Length=269, Percent_Identity=28.6245353159851, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI71992966, Length=240, Percent_Identity=30.4166666666667, Blast_Score=88, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17558372, Length=202, Percent_Identity=30.6930693069307, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17531429, Length=235, Percent_Identity=32.3404255319149, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17531431, Length=235, Percent_Identity=32.3404255319149, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71992961, Length=238, Percent_Identity=29.8319327731092, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI71994009, Length=238, Percent_Identity=28.9915966386555, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321054, Length=226, Percent_Identity=27.4336283185841, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24652747, Length=243, Percent_Identity=34.5679012345679, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI45551084, Length=243, Percent_Identity=34.5679012345679, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24652751, Length=235, Percent_Identity=29.7872340425532, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI19922038, Length=235, Percent_Identity=29.7872340425532, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24762344, Length=242, Percent_Identity=30.5785123966942, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24762346, Length=225, Percent_Identity=30.6666666666667, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24762348, Length=225, Percent_Identity=30.6666666666667, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI20130305, Length=225, Percent_Identity=30.6666666666667, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24762342, Length=202, Percent_Identity=29.2079207920792, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI45550503, Length=227, Percent_Identity=27.7533039647577, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI17136672, Length=223, Percent_Identity=28.6995515695067, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012269
- InterPro:   IPR000425
- InterPro:   IPR022357 [H]

Pfam domain/function: PF00230 MIP [H]

EC number: NA

Molecular weight: Translated: 26135; Mature: 26135

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: PS00221 MIP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCCCCCC
>Mature Secondary Structure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HHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: H2O [Periplasm] [C]

Specific reaction: H2O [Periplasm] = H2O [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]