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The map label for this gene is dgoD1 [H]

Identifier: 284159399

GI number: 284159399

Start: 696474

End: 697982

Strand: Reverse

Name: dgoD1 [H]

Synonym: BTH_I0611

Alternate gene names: 284159399

Gene position: 697982-696474 (Counterclockwise)

Preceding gene: 83718882

Following gene: 83719783

Centisome position: 18.32

GC content: 67.33

Gene sequence:

>1509_bases
TTGGATCGGTTCCGGCGCGGCGGCGCGGCGGCGCCGCGCTCTGACGACCGGCCGGTGGCGTACGGTAACGCCCGGCCGGG
CGAATCGCAACCGCCCGGGCGACGAGCCGCGAGCGACGGGCGACAAATCGCACCCGACCCGACTCGCGCGCCGCCGCGCT
CACTATGTGCACAACGTCGCGATCGATACTACTTTCGCGCGACGCCGCTGTACGATTCACGCGTGATTCAAGCAGACAGC
CCGCCGACGGTCTCGCAAAAGGCACAAGCCGTGCCGCGGCAGCCCACCGGTTCGGCCGCTGGCGCTGCGCGCAGCCCACC
GAGATCCGAAGCAAATCGAAGATACAAGGAGACACCCGCCATGAAAATCACCCGCCTCGAAACCTTCATCGTGCCGCCTC
GATGGCTGTTCCTGAAGATCGAGACCGACGCGGGCATCGTCGGCTGGGGCGAGCCGATCGTCGAAGGCCGCGCGCACACG
GTCGAGGCGGCCGTGCACGAGCTCGCCGACTACCTCGTCGGCCAGGACCCGCTTCGCATCGAGGACCACTGGCAGGTGAT
GTACCGCGCGGGCTTCTACCGCGGCGGCCCGATCGCGATGAGCGCGATCGCGGGCATCGACCAGGCGCTCTGGGACATCA
AGGGCAAGCATCACGGCGCGCCCGTCCATACCCTCCTCGGCGGCCCCGTGCGCGACCGGATCAAGGTGTATTCATGGATC
GGCGGCGACCGGCCGAGCGACGTCGCGAACAACGCGCGCGCGGTCGTCGAGCGCGGCTTCCAGGCCGTGAAGATGAACGG
CTCGGAGGAATTGCAGATCGTCGACACTTTCGACAAGGTCGACAAGGTGATCGCGAACGTCGCGGCGGTGCGCGACGCGG
TGGGCCCTTACGTCGGCATCGGCGTCGATTTCCACGGCCGCGTGCACAAGCCGATGGCGAAAGTGCTCGCGAAGGAGCTC
GATCCGTACAAGCTGATGTTCATCGAGGAGCCCGTGCTGTCGGAGAACGCCGAGGCGCTGCGCGACATCGCGAACCAAAC
GAGCACGCCGATCGCGCTCGGCGAACGGCTCTACTCGCGCTGGGACTTCAAGTACATCCTCGAAGGCGGCTACGTCGACA
TCGTGCAGCCCGATGCGTCGCACGCGGGCGGGATCACCGAGTGCCGCAAAATCGCGACGCTCGCGGAAAGCTACGACGTC
GCGCTCGCGCTGCACTGCCCGCTCGGGCCGATCGCGCTCGCAGCGTGCCTGCAGCTCGATGCCGTCAGCTACAACGCGTT
CATTCAGGAACAGAGCCTCGGCATCCACTACAACCAGGGCAGCGATCTGCTCGACTATCTCCGCAACCCCGAGGTGTTCC
GCTACGCGGACGGCTTCGTCGCGATTCCGCAGGAGCCGGGGCTCGGCATCGACGTCGACGAGGAAAAAGTGCGGGAGATG
GCGAAGACCGGGCACCGGTGGCGCAATCCGGTGTGGCGGCACGCGGACGGCAGCGTCGCCGAGTGGTGA

Upstream 100 bases:

>100_bases
CATCGAGCAGTTGCACGCGCACGCCGCGTCGATCTCCCCTTCCACCTCGAACCTGACCTTGCCGCAATGGCAGCCACCGG
TGTAAAGCATCGTCGCCTCC

Downstream 100 bases:

>100_bases
CGATGCGCGCGGCCGCGCGGGTAAGCGGCCGAGCCGCTGATCGGCTGATCGGCTGGGCAGCCGTGCGGCGAATCGGCCGA
TCAAGTCAGGTGTCGGCGGC

Product: galactonate dehydratase

Products: NA

Alternate protein names: GalD 1 [H]

Number of amino acids: Translated: 502; Mature: 502

Protein sequence:

>502_residues
MDRFRRGGAAAPRSDDRPVAYGNARPGESQPPGRRAASDGRQIAPDPTRAPPRSLCAQRRDRYYFRATPLYDSRVIQADS
PPTVSQKAQAVPRQPTGSAAGAARSPPRSEANRRYKETPAMKITRLETFIVPPRWLFLKIETDAGIVGWGEPIVEGRAHT
VEAAVHELADYLVGQDPLRIEDHWQVMYRAGFYRGGPIAMSAIAGIDQALWDIKGKHHGAPVHTLLGGPVRDRIKVYSWI
GGDRPSDVANNARAVVERGFQAVKMNGSEELQIVDTFDKVDKVIANVAAVRDAVGPYVGIGVDFHGRVHKPMAKVLAKEL
DPYKLMFIEEPVLSENAEALRDIANQTSTPIALGERLYSRWDFKYILEGGYVDIVQPDASHAGGITECRKIATLAESYDV
ALALHCPLGPIALAACLQLDAVSYNAFIQEQSLGIHYNQGSDLLDYLRNPEVFRYADGFVAIPQEPGLGIDVDEEKVREM
AKTGHRWRNPVWRHADGSVAEW

Sequences:

>Translated_502_residues
MDRFRRGGAAAPRSDDRPVAYGNARPGESQPPGRRAASDGRQIAPDPTRAPPRSLCAQRRDRYYFRATPLYDSRVIQADS
PPTVSQKAQAVPRQPTGSAAGAARSPPRSEANRRYKETPAMKITRLETFIVPPRWLFLKIETDAGIVGWGEPIVEGRAHT
VEAAVHELADYLVGQDPLRIEDHWQVMYRAGFYRGGPIAMSAIAGIDQALWDIKGKHHGAPVHTLLGGPVRDRIKVYSWI
GGDRPSDVANNARAVVERGFQAVKMNGSEELQIVDTFDKVDKVIANVAAVRDAVGPYVGIGVDFHGRVHKPMAKVLAKEL
DPYKLMFIEEPVLSENAEALRDIANQTSTPIALGERLYSRWDFKYILEGGYVDIVQPDASHAGGITECRKIATLAESYDV
ALALHCPLGPIALAACLQLDAVSYNAFIQEQSLGIHYNQGSDLLDYLRNPEVFRYADGFVAIPQEPGLGIDVDEEKVREM
AKTGHRWRNPVWRHADGSVAEW
>Mature_502_residues
MDRFRRGGAAAPRSDDRPVAYGNARPGESQPPGRRAASDGRQIAPDPTRAPPRSLCAQRRDRYYFRATPLYDSRVIQADS
PPTVSQKAQAVPRQPTGSAAGAARSPPRSEANRRYKETPAMKITRLETFIVPPRWLFLKIETDAGIVGWGEPIVEGRAHT
VEAAVHELADYLVGQDPLRIEDHWQVMYRAGFYRGGPIAMSAIAGIDQALWDIKGKHHGAPVHTLLGGPVRDRIKVYSWI
GGDRPSDVANNARAVVERGFQAVKMNGSEELQIVDTFDKVDKVIANVAAVRDAVGPYVGIGVDFHGRVHKPMAKVLAKEL
DPYKLMFIEEPVLSENAEALRDIANQTSTPIALGERLYSRWDFKYILEGGYVDIVQPDASHAGGITECRKIATLAESYDV
ALALHCPLGPIALAACLQLDAVSYNAFIQEQSLGIHYNQGSDLLDYLRNPEVFRYADGFVAIPQEPGLGIDVDEEKVREM
AKTGHRWRNPVWRHADGSVAEW

Specific function: Catalyzes the dehydration of D-galactonate to 2-keto-3- deoxy-D-galactonate [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily [H]

Homologues:

Organism=Escherichia coli, GI48994953, Length=382, Percent_Identity=63.6125654450262, Blast_Score=518, Evalue=1e-148,
Organism=Escherichia coli, GI1787864, Length=414, Percent_Identity=31.6425120772947, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI226510960, Length=268, Percent_Identity=30.5970149253731, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018110
- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =4.2.1.6 [H]

Molecular weight: Translated: 55423; Mature: 55423

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: PS00908 MR_MLE_1 ; PS00909 MR_MLE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRFRRGGAAAPRSDDRPVAYGNARPGESQPPGRRAASDGRQIAPDPTRAPPRSLCAQRR
CCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCHHCCCCCCCCCCCCCCHHHHHHHHH
DRYYFRATPLYDSRVIQADSPPTVSQKAQAVPRQPTGSAAGAARSPPRSEANRRYKETPA
CCEEEEECCCCCCEEEECCCCCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCC
MKITRLETFIVPPRWLFLKIETDAGIVGWGEPIVEGRAHTVEAAVHELADYLVGQDPLRI
EEEEEEEEEECCCEEEEEEEECCCCEEECCCHHHCCCHHHHHHHHHHHHHHHHCCCCCEE
EDHWQVMYRAGFYRGGPIAMSAIAGIDQALWDIKGKHHGAPVHTLLGGPVRDRIKVYSWI
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCHHHHHEEEEEC
GGDRPSDVANNARAVVERGFQAVKMNGSEELQIVDTFDKVDKVIANVAAVRDAVGPYVGI
CCCCCHHHHHHHHHHHHCCCCEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCEEEE
GVDFHGRVHKPMAKVLAKELDPYKLMFIEEPVLSENAEALRDIANQTSTPIALGERLYSR
CCCCCCCHHHHHHHHHHHHCCCEEEEEEECCHHCCCHHHHHHHHHCCCCCHHHHHHHHHH
WDFKYILEGGYVDIVQPDASHAGGITECRKIATLAESYDVALALHCPLGPIALAACLQLD
CCEEEEEECCEEEEECCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHH
AVSYNAFIQEQSLGIHYNQGSDLLDYLRNPEVFRYADGFVAIPQEPGLGIDVDEEKVREM
HHHHHHEEECCCCCEEECCCCHHHHHHCCCCEEEECCCEEECCCCCCCCCCCCHHHHHHH
AKTGHRWRNPVWRHADGSVAEW
HHCCHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDRFRRGGAAAPRSDDRPVAYGNARPGESQPPGRRAASDGRQIAPDPTRAPPRSLCAQRR
CCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCHHCCCCCCCCCCCCCCHHHHHHHHH
DRYYFRATPLYDSRVIQADSPPTVSQKAQAVPRQPTGSAAGAARSPPRSEANRRYKETPA
CCEEEEECCCCCCEEEECCCCCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCC
MKITRLETFIVPPRWLFLKIETDAGIVGWGEPIVEGRAHTVEAAVHELADYLVGQDPLRI
EEEEEEEEEECCCEEEEEEEECCCCEEECCCHHHCCCHHHHHHHHHHHHHHHHCCCCCEE
EDHWQVMYRAGFYRGGPIAMSAIAGIDQALWDIKGKHHGAPVHTLLGGPVRDRIKVYSWI
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCHHHHHEEEEEC
GGDRPSDVANNARAVVERGFQAVKMNGSEELQIVDTFDKVDKVIANVAAVRDAVGPYVGI
CCCCCHHHHHHHHHHHHCCCCEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCEEEE
GVDFHGRVHKPMAKVLAKELDPYKLMFIEEPVLSENAEALRDIANQTSTPIALGERLYSR
CCCCCCCHHHHHHHHHHHHCCCEEEEEEECCHHCCCHHHHHHHHHCCCCCHHHHHHHHHH
WDFKYILEGGYVDIVQPDASHAGGITECRKIATLAESYDVALALHCPLGPIALAACLQLD
CCEEEEEECCEEEEECCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHH
AVSYNAFIQEQSLGIHYNQGSDLLDYLRNPEVFRYADGFVAIPQEPGLGIDVDEEKVREM
HHHHHHEEECCCCCEEECCCCHHHHHHCCCCEEEECCCEEECCCCCCCCCCCCHHHHHHH
AKTGHRWRNPVWRHADGSVAEW
HHCCHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA