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The map label for this gene is zraS [C]

Identifier: 83718882

GI number: 83718882

Start: 700127

End: 702007

Strand: Reverse

Name: zraS [C]

Synonym: BTH_I0614

Alternate gene names: 83718882

Gene position: 702007-700127 (Counterclockwise)

Preceding gene: 83720806

Following gene: 284159399

Centisome position: 18.43

GC content: 68.95

Gene sequence:

>1881_bases
ATGCATGGAACCTTCGATCTCCCGCTCGTCACGCTGTCGCTCGCGATCGCGACGCTCGCGTCGTATACGGCGCTCGACCT
GAGCGCGCTCATCGCGCTTCTCGACCAGCCCCGGATGCGGCGCGCGTGGCTCGCGGGCGGCGCGGCCGCGATGGGCACGG
GCATCTGGGCGATGCACTTCGTCGGCATGCTCGCGTTCTCGCTGCCGATCCCGCTCGGCTACGACTTCGGCTACACGTTC
GCATCCCTCGCGATCGCGGTGATCGTGTCGTACTTCGCGCTCGACGCGCTCACGCGCGCCGCGCTCACGCGCGAGCGGCT
CGCGATGGGCGGCGTGCTGATGGGGATCGGCATCGCGGGCATGCATTACACCGGCATGAGCGCGCTGCGGATGCAGCCCG
CGATCGACTACGACTTCACGTTGTTCGTCGCATCGATCGCGATTGCGATCGGCGCGTCGACGACCGCGCTGTGGATCGCG
CATCGCCTGAGCAACGAGAACGAGCCGCGCGTGCTCTCGAAGCGGATCGCCGCAGCGGGCGTGATGGGCATCGCGATCAC
CGGCATGCATTACACGGGGATGGCGGCCGCGCACTTCGCGGCGAACTCGGTGTGCGGCGCGGCGGGCGAGATCAGCGGCG
CGTGGCTCGGCGCGACGATCGCGCTCTTCACCGTGACGATCCTGAGCGCGACGCTCGTCGTATCGCGCTTCGACGCGCGC
ACCGCGTTCCTGCGCGGCATGACCGACGCGCTCGAGGAACTCGTCGCGAAGCGCACGAGCGAGCTCGAAGGCGCGCTGCG
GCAATACGAGCGCACGACGCACGTGCTGCAGCGCACGCGCAGGAAGATGGAGCAGGAGATCGACGAACGCAAGGCCGCGC
AGGCGCGTCTCGAGCACGAGAAGGAGGAGCAGCGCCGCCTGATCCGGCGGCTCGAGGAAACGTACGTGCAACTGCTGCAA
TCGGAAAAGCTCGCGTCGATCGGCCAGCTCGCGGCGGGCGTCGCTCACGAGATCAACAACCCGATCGGCTTCGTCAACGC
GAACCTGAACACGCTGAAGAGCTGGGTCGCAGGTCTCCTCGACGTGATCGCCGTGCAGGAAGCGCTGACGAGCACGCTCG
GGCCCGATGCGCGCGCGCCGCTCGCCGCGGTGGCGCGCGACGTCGATCTCGATTACGTGCGCGGCGACATCATCGCGCTC
ATCGACGAATCGATCGACGGCGCGATGCGTGTGCGGCGCATCGTCTGCGACCTGCGCGATTTCTCGCGGCCGAGCGGCGA
CGCGTGGGCGTTCGCCGATCTGCACGCGAGCCTCGAGAGCACGCTGAACGTCGTCCACAACGAGCTCAAGTACAAGGCGG
ACGTCGTGCGCGAATACGGCCGCCTGCCGCTCGTCGAATGCAACGCCGCGCAGTTGAGCCAGGTGTTCATGAACCTGCTC
GTGAACGCCGCGCAGTCGATCGGCACGCACGGCACGATCACGATTCGCACGACGTGCGACGCCGACACCGTGTCAATCTC
GATCGCCGACACGGGCGCGGGCATTCCGGACGACGTGATCGGCAAGATCTTCGATCCGTTCTTCACGACGAAGCCGGTCG
GCCAGGGCACGGGGCTCGGGCTGTCGATCTCGCACGGCATCGTCGAGCATCACGGCGGGCGCATCGACGTCGAGAGCCGC
ATCGGACGAGGCTCGACGTTTACGGTCACGCTGCCGATCCGGCGCAAGTCCGGCCCGGCCGCGCGGACGCAGACGAGCGA
CGAGGCGAGCGATGAGACTAGCGACGAGGCGAGCCGCGCGAGCGCCGTGCGCGCGGCGGCCCGCGCAATCGGGCGCGCCG
CCGCGCCGGCGGCGCCGCTTACGCGCGGCGCGGCTTGCTGA

Upstream 100 bases:

>100_bases
ACGCCGTTCACGATCCTGATCCAGACGATGCCGCTCGCCGAGGCGGCGGCGGCAGCCGGACACGAATGCTGACGCGCGCG
CCGGCAAGCGCCAACGGCCC

Downstream 100 bases:

>100_bases
GCACGATCGTCTCGAACAGCTCGTACTCGGCCGTCGGCTTCTGGTCGGCGCCCGGCGCGTGATAGTAGTTCACCGTGATC
GTCGAGTGGCCGCCGTGCTC

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 626; Mature: 626

Protein sequence:

>626_residues
MHGTFDLPLVTLSLAIATLASYTALDLSALIALLDQPRMRRAWLAGGAAAMGTGIWAMHFVGMLAFSLPIPLGYDFGYTF
ASLAIAVIVSYFALDALTRAALTRERLAMGGVLMGIGIAGMHYTGMSALRMQPAIDYDFTLFVASIAIAIGASTTALWIA
HRLSNENEPRVLSKRIAAAGVMGIAITGMHYTGMAAAHFAANSVCGAAGEISGAWLGATIALFTVTILSATLVVSRFDAR
TAFLRGMTDALEELVAKRTSELEGALRQYERTTHVLQRTRRKMEQEIDERKAAQARLEHEKEEQRRLIRRLEETYVQLLQ
SEKLASIGQLAAGVAHEINNPIGFVNANLNTLKSWVAGLLDVIAVQEALTSTLGPDARAPLAAVARDVDLDYVRGDIIAL
IDESIDGAMRVRRIVCDLRDFSRPSGDAWAFADLHASLESTLNVVHNELKYKADVVREYGRLPLVECNAAQLSQVFMNLL
VNAAQSIGTHGTITIRTTCDADTVSISIADTGAGIPDDVIGKIFDPFFTTKPVGQGTGLGLSISHGIVEHHGGRIDVESR
IGRGSTFTVTLPIRRKSGPAARTQTSDEASDETSDEASRASAVRAAARAIGRAAAPAAPLTRGAAC

Sequences:

>Translated_626_residues
MHGTFDLPLVTLSLAIATLASYTALDLSALIALLDQPRMRRAWLAGGAAAMGTGIWAMHFVGMLAFSLPIPLGYDFGYTF
ASLAIAVIVSYFALDALTRAALTRERLAMGGVLMGIGIAGMHYTGMSALRMQPAIDYDFTLFVASIAIAIGASTTALWIA
HRLSNENEPRVLSKRIAAAGVMGIAITGMHYTGMAAAHFAANSVCGAAGEISGAWLGATIALFTVTILSATLVVSRFDAR
TAFLRGMTDALEELVAKRTSELEGALRQYERTTHVLQRTRRKMEQEIDERKAAQARLEHEKEEQRRLIRRLEETYVQLLQ
SEKLASIGQLAAGVAHEINNPIGFVNANLNTLKSWVAGLLDVIAVQEALTSTLGPDARAPLAAVARDVDLDYVRGDIIAL
IDESIDGAMRVRRIVCDLRDFSRPSGDAWAFADLHASLESTLNVVHNELKYKADVVREYGRLPLVECNAAQLSQVFMNLL
VNAAQSIGTHGTITIRTTCDADTVSISIADTGAGIPDDVIGKIFDPFFTTKPVGQGTGLGLSISHGIVEHHGGRIDVESR
IGRGSTFTVTLPIRRKSGPAARTQTSDEASDETSDEASRASAVRAAARAIGRAAAPAAPLTRGAAC
>Mature_626_residues
MHGTFDLPLVTLSLAIATLASYTALDLSALIALLDQPRMRRAWLAGGAAAMGTGIWAMHFVGMLAFSLPIPLGYDFGYTF
ASLAIAVIVSYFALDALTRAALTRERLAMGGVLMGIGIAGMHYTGMSALRMQPAIDYDFTLFVASIAIAIGASTTALWIA
HRLSNENEPRVLSKRIAAAGVMGIAITGMHYTGMAAAHFAANSVCGAAGEISGAWLGATIALFTVTILSATLVVSRFDAR
TAFLRGMTDALEELVAKRTSELEGALRQYERTTHVLQRTRRKMEQEIDERKAAQARLEHEKEEQRRLIRRLEETYVQLLQ
SEKLASIGQLAAGVAHEINNPIGFVNANLNTLKSWVAGLLDVIAVQEALTSTLGPDARAPLAAVARDVDLDYVRGDIIAL
IDESIDGAMRVRRIVCDLRDFSRPSGDAWAFADLHASLESTLNVVHNELKYKADVVREYGRLPLVECNAAQLSQVFMNLL
VNAAQSIGTHGTITIRTTCDADTVSISIADTGAGIPDDVIGKIFDPFFTTKPVGQGTGLGLSISHGIVEHHGGRIDVESR
IGRGSTFTVTLPIRRKSGPAARTQTSDEASDETSDEASRASAVRAAARAIGRAAAPAAPLTRGAAC

Specific function: Member Of The Two-Component Regulatory System Zras/Zrar. May Function As A Membrane-Associated Protein Kinase That Phosphorylates Zrar In Response To High Concentrations Of Zinc Or Lead In The Medium. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=271, Percent_Identity=33.5793357933579, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI1788549, Length=265, Percent_Identity=33.5849056603774, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI145693157, Length=322, Percent_Identity=26.3975155279503, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790300, Length=274, Percent_Identity=28.4671532846715, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI48994928, Length=119, Percent_Identity=36.1344537815126, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI87081816, Length=112, Percent_Identity=33.9285714285714, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1786912, Length=113, Percent_Identity=33.6283185840708, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788393, Length=109, Percent_Identity=35.7798165137615, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: 2.7.3.- [C]

Molecular weight: Translated: 66853; Mature: 66853

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50924 MHYT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHGTFDLPLVTLSLAIATLASYTALDLSALIALLDQPRMRRAWLAGGAAAMGTGIWAMHF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHH
VGMLAFSLPIPLGYDFGYTFASLAIAVIVSYFALDALTRAALTRERLAMGGVLMGIGIAG
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
MHYTGMSALRMQPAIDYDFTLFVASIAIAIGASTTALWIAHRLSNENEPRVLSKRIAAAG
HHHCCCHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHH
VMGIAITGMHYTGMAAAHFAANSVCGAAGEISGAWLGATIALFTVTILSATLVVSRFDAR
HHHHHEECCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAFLRGMTDALEELVAKRTSELEGALRQYERTTHVLQRTRRKMEQEIDERKAAQARLEHE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEEQRRLIRRLEETYVQLLQSEKLASIGQLAAGVAHEINNPIGFVNANLNTLKSWVAGLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHH
DVIAVQEALTSTLGPDARAPLAAVARDVDLDYVRGDIIALIDESIDGAMRVRRIVCDLRD
HHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHHHEEHHHCCHHHHHHHHHHHHHHH
FSRPSGDAWAFADLHASLESTLNVVHNELKYKADVVREYGRLPLVECNAAQLSQVFMNLL
CCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHH
VNAAQSIGTHGTITIRTTCDADTVSISIADTGAGIPDDVIGKIFDPFFTTKPVGQGTGLG
HHHHHHCCCCCEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHCHHHCCCCCCCCCCCC
LSISHGIVEHHGGRIDVESRIGRGSTFTVTLPIRRKSGPAARTQTSDEASDETSDEASRA
EECCCCHHHHCCCEEEHHHHCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHH
SAVRAAARAIGRAAAPAAPLTRGAAC
HHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MHGTFDLPLVTLSLAIATLASYTALDLSALIALLDQPRMRRAWLAGGAAAMGTGIWAMHF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHH
VGMLAFSLPIPLGYDFGYTFASLAIAVIVSYFALDALTRAALTRERLAMGGVLMGIGIAG
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
MHYTGMSALRMQPAIDYDFTLFVASIAIAIGASTTALWIAHRLSNENEPRVLSKRIAAAG
HHHCCCHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHH
VMGIAITGMHYTGMAAAHFAANSVCGAAGEISGAWLGATIALFTVTILSATLVVSRFDAR
HHHHHEECCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAFLRGMTDALEELVAKRTSELEGALRQYERTTHVLQRTRRKMEQEIDERKAAQARLEHE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEEQRRLIRRLEETYVQLLQSEKLASIGQLAAGVAHEINNPIGFVNANLNTLKSWVAGLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHH
DVIAVQEALTSTLGPDARAPLAAVARDVDLDYVRGDIIALIDESIDGAMRVRRIVCDLRD
HHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHHHEEHHHCCHHHHHHHHHHHHHHH
FSRPSGDAWAFADLHASLESTLNVVHNELKYKADVVREYGRLPLVECNAAQLSQVFMNLL
CCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHH
VNAAQSIGTHGTITIRTTCDADTVSISIADTGAGIPDDVIGKIFDPFFTTKPVGQGTGLG
HHHHHHCCCCCEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHCHHHCCCCCCCCCCCC
LSISHGIVEHHGGRIDVESRIGRGSTFTVTLPIRRKSGPAARTQTSDEASDETSDEASRA
EECCCCHHHHCCCEEEHHHHCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHH
SAVRAAARAIGRAAAPAAPLTRGAAC
HHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]