| Definition | Burkholderia thailandensis E264 chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_007651 |
| Length | 3,809,201 |
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The map label for this gene is gyrB [H]
Identifier: 161723181
GI number: 161723181
Start: 3693412
End: 3695880
Strand: Direct
Name: gyrB [H]
Synonym: BTH_I3241
Alternate gene names: 161723181
Gene position: 3693412-3695880 (Clockwise)
Preceding gene: 83720585
Following gene: 83720538
Centisome position: 96.96
GC content: 64.32
Gene sequence:
>2469_bases ATGACTGAACAGCACAATTCGCAGCCCGAAAATAGCTACGGCGCGTCGTCGATCCAGATCCTCGAAGGCCTGGAAGCGGT GCGCAAGCGACCCGGGATGTACATCGGCGACACGTCGGACGGCACCGGTCTGCACCACCTCGTGTTCGAGGTGCTCGACA ACTCGATCGACGAAGCGCTTGCCGGCTACTGCAACGACATCCACGTGACCATTCACGCGGACAATTCGATCTCCGTGACC GACAACGGCCGCGGCATCCCGACCGACGTCAAGCTCAACGACAAGCACGAACCGAAGCGCTCGGCCGCCGAGATCGTGAT GACCGAGCTGCACGCGGGCGGCAAGTTCGACCAGAACAGCTACAAGGTGTCGGGCGGCCTGCACGGCGTCGGCGTATCGT GCGTGAACGCGCTCTCCAGCTGGCTGCGCCTCACCGTGCGCCGCGACGGCAAGAAGCACTTCATGGAATTCCATCGCGGC ATCGCGCAGAACCGCGTGCTCGAGGAGCGCGACGGCGAGCAGGTGTCGCCGATGCAGGTGATCGGCGACACCGAGAACCG CGGCACCGAAGTGCACTTCATGGCCGATTCGACGATCTTCGGCACCGTCGAATACCACTACGACATCCTCGCGAAACGCA TCCGCGAGCTGTCGTTCCTGAACAACGGCGTGCGCATCCGCCTGACCGACCAGCGCTCCGGCAAGGAAGACGATTTCGCG TTCGCGGGCGGCGTGAAGGGCTTCGTCGAGTACATCAACAAGACGAAGAGCGTGCTGCATCCGACGATCTTCCACATCAA CGGCGAGAAGGACGGCGTCGGCGTGGAAGTGGCGATGCAGTGGAATGACAGCTACAACGAAAACGTGCTGTGCTTCACGA ACAACATCCCGCAGCGCGACGGCGGCACGCACTTGACCGGCCTGCGCGCGGCGATGACGCGCGTGATCAACAAGTACATC GCCGACAACGAAATCGCGAAGAAGGCAAAGGTCGAGACGAGCGGCGACGACATGCGCGAAGGGCTTTCGTGCGTGCTGTC GGTGAAGGTGCCGGAGCCGAAGTTCAGCTCGCAGACGAAGGACAAGCTGGTTTCGTCCGAAGTGCGCGCGCCGGTGGAGG AAGTGGTGGCGAAGGCGCTCGAGGAGTTCCTGCTCGAAACGCCGAACGACGCGAAGATCATCTGCGGCAAGATCGTCGAA GCGGCGCGCGCGCGCGATGCCGCGCGCAAGGCGCGCGAGATGACGCGCCGCAAGGGCGTGCTCGACGGCGTGGGCCTGCC GGGCAAGCTCGCGGATTGCCAGGAGAAGGACCCGGCGAAATCGGAGATCTACATCGTCGAGGGCGATTCGGCGGGCGGCT CGGCGAAGCAAGGGCGCGACCGCAAGTTCCAGGCGATCCTGCCGCTGCGCGGCAAGGTGCTGAACGTGGAGAAGGCGCGC TACGACAAGCTGCTGTCGTCCGAGCAGATCGTCACGCTCGTGACCGCGCTCGGCTGCGGGATCGGCAAGGACGACTACAA CCTCGACAAGCTGCGCTACCACCGGATCATCATCATGACCGATGCGGACGTGGACGGCGCGCACATCCGCACGCTGCTGC TGACGTTCTTCTACCGGCAGATGCCGGAGATGATCGAGCGCGGCTACGTGTACATCGCGCAGCCGCCGCTCTACAAGGTG AAGGCTGGCCGCGACGAGCGCTACCTGAAGGACGACACCGAGCTGAACGCGCACATGCTGCGCCTCGCGCTGCAGGGCTC GGAGCTCGTGCCGACCGAGAACGGCACACCGATCTCGGGCGACGCGCTCGGCGAGCTTGCGCGCTCGTATCTGCTCGCGC GGGGCGTGGTGGAGCGGCTGAGCCGCCTGTACGACCCGGCCGCGCTCGAGGCGGTCATGGACGGCGTCGCGATCGATCTG TCGAGCGAGGCGTCGACGGAGGCGTCGGCGAAGGCGCTGGCCGCCATGCTGTCCGACGATTCGAAGACCGAAGTGCGCGT CGTGCCCGCTTACGATGCGGTGCGCGAGCAGCGCTCGCTGCGTGTCGAGCGCACGCATCACGGCAACGTGCGCGTATCGG TGATCGACGAGGAGTTCCAGCACACGGCTGATTATCAGCAACTCGTAAACACCGCGAATACGTTCAAGGGTTTGATCGGC GCGGGGGCGGCGATCAAGCGCGGCGAACGGAGCTCGAACGTGGCGGACTTCAAGGAAGCGATGAAGTGGCTGATGGCCGA CGCCGAGCGGAACATGTCTAAGCAGCGGTATAAGGGGTTGGGCGAGATGAACCCCGAGCAGCTGTGGGAAACGACGATGG ACCCGGCGGTGCGGCGGTTGCTGCGCGTGCAGATCGAGGATGCGATTGCGGCGGATGGGATCTTTACCACCCTCATGGGG GACGAGGTCGAGCCGCGACGGGCGTTTATCGAGAATAATGCGTTGCGGGCGGGGAATATTGATGTTTGA
Upstream 100 bases:
>100_bases GCCGGCCCCCGAAAGGGGCGAAAAACCCGAGGCGGCCCGGTTTTTTCGGCGGAAGCACCCCGCCGCCACTCGAGTAGCCC AGCAGAACCGGAAGACACCC
Downstream 100 bases:
>100_bases GGTTGTGTAGCGGGAACCATAATGTGAGATTTTGGGAAGCATCCATTGAGACATTTATTGGTGGATGCATTCCAATAGCT CTAATGACGTCATCTAACTG
Product: DNA gyrase subunit B
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 822; Mature: 821
Protein sequence:
>822_residues MTEQHNSQPENSYGASSIQILEGLEAVRKRPGMYIGDTSDGTGLHHLVFEVLDNSIDEALAGYCNDIHVTIHADNSISVT DNGRGIPTDVKLNDKHEPKRSAAEIVMTELHAGGKFDQNSYKVSGGLHGVGVSCVNALSSWLRLTVRRDGKKHFMEFHRG IAQNRVLEERDGEQVSPMQVIGDTENRGTEVHFMADSTIFGTVEYHYDILAKRIRELSFLNNGVRIRLTDQRSGKEDDFA FAGGVKGFVEYINKTKSVLHPTIFHINGEKDGVGVEVAMQWNDSYNENVLCFTNNIPQRDGGTHLTGLRAAMTRVINKYI ADNEIAKKAKVETSGDDMREGLSCVLSVKVPEPKFSSQTKDKLVSSEVRAPVEEVVAKALEEFLLETPNDAKIICGKIVE AARARDAARKAREMTRRKGVLDGVGLPGKLADCQEKDPAKSEIYIVEGDSAGGSAKQGRDRKFQAILPLRGKVLNVEKAR YDKLLSSEQIVTLVTALGCGIGKDDYNLDKLRYHRIIIMTDADVDGAHIRTLLLTFFYRQMPEMIERGYVYIAQPPLYKV KAGRDERYLKDDTELNAHMLRLALQGSELVPTENGTPISGDALGELARSYLLARGVVERLSRLYDPAALEAVMDGVAIDL SSEASTEASAKALAAMLSDDSKTEVRVVPAYDAVREQRSLRVERTHHGNVRVSVIDEEFQHTADYQQLVNTANTFKGLIG AGAAIKRGERSSNVADFKEAMKWLMADAERNMSKQRYKGLGEMNPEQLWETTMDPAVRRLLRVQIEDAIAADGIFTTLMG DEVEPRRAFIENNALRAGNIDV
Sequences:
>Translated_822_residues MTEQHNSQPENSYGASSIQILEGLEAVRKRPGMYIGDTSDGTGLHHLVFEVLDNSIDEALAGYCNDIHVTIHADNSISVT DNGRGIPTDVKLNDKHEPKRSAAEIVMTELHAGGKFDQNSYKVSGGLHGVGVSCVNALSSWLRLTVRRDGKKHFMEFHRG IAQNRVLEERDGEQVSPMQVIGDTENRGTEVHFMADSTIFGTVEYHYDILAKRIRELSFLNNGVRIRLTDQRSGKEDDFA FAGGVKGFVEYINKTKSVLHPTIFHINGEKDGVGVEVAMQWNDSYNENVLCFTNNIPQRDGGTHLTGLRAAMTRVINKYI ADNEIAKKAKVETSGDDMREGLSCVLSVKVPEPKFSSQTKDKLVSSEVRAPVEEVVAKALEEFLLETPNDAKIICGKIVE AARARDAARKAREMTRRKGVLDGVGLPGKLADCQEKDPAKSEIYIVEGDSAGGSAKQGRDRKFQAILPLRGKVLNVEKAR YDKLLSSEQIVTLVTALGCGIGKDDYNLDKLRYHRIIIMTDADVDGAHIRTLLLTFFYRQMPEMIERGYVYIAQPPLYKV KAGRDERYLKDDTELNAHMLRLALQGSELVPTENGTPISGDALGELARSYLLARGVVERLSRLYDPAALEAVMDGVAIDL SSEASTEASAKALAAMLSDDSKTEVRVVPAYDAVREQRSLRVERTHHGNVRVSVIDEEFQHTADYQQLVNTANTFKGLIG AGAAIKRGERSSNVADFKEAMKWLMADAERNMSKQRYKGLGEMNPEQLWETTMDPAVRRLLRVQIEDAIAADGIFTTLMG DEVEPRRAFIENNALRAGNIDV >Mature_821_residues TEQHNSQPENSYGASSIQILEGLEAVRKRPGMYIGDTSDGTGLHHLVFEVLDNSIDEALAGYCNDIHVTIHADNSISVTD NGRGIPTDVKLNDKHEPKRSAAEIVMTELHAGGKFDQNSYKVSGGLHGVGVSCVNALSSWLRLTVRRDGKKHFMEFHRGI AQNRVLEERDGEQVSPMQVIGDTENRGTEVHFMADSTIFGTVEYHYDILAKRIRELSFLNNGVRIRLTDQRSGKEDDFAF AGGVKGFVEYINKTKSVLHPTIFHINGEKDGVGVEVAMQWNDSYNENVLCFTNNIPQRDGGTHLTGLRAAMTRVINKYIA DNEIAKKAKVETSGDDMREGLSCVLSVKVPEPKFSSQTKDKLVSSEVRAPVEEVVAKALEEFLLETPNDAKIICGKIVEA ARARDAARKAREMTRRKGVLDGVGLPGKLADCQEKDPAKSEIYIVEGDSAGGSAKQGRDRKFQAILPLRGKVLNVEKARY DKLLSSEQIVTLVTALGCGIGKDDYNLDKLRYHRIIIMTDADVDGAHIRTLLLTFFYRQMPEMIERGYVYIAQPPLYKVK AGRDERYLKDDTELNAHMLRLALQGSELVPTENGTPISGDALGELARSYLLARGVVERLSRLYDPAALEAVMDGVAIDLS SEASTEASAKALAAMLSDDSKTEVRVVPAYDAVREQRSLRVERTHHGNVRVSVIDEEFQHTADYQQLVNTANTFKGLIGA GAAIKRGERSSNVADFKEAMKWLMADAERNMSKQRYKGLGEMNPEQLWETTMDPAVRRLLRVQIEDAIAADGIFTTLMGD EVEPRRAFIENNALRAGNIDV
Specific function: DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings [H]
COG id: COG0187
COG function: function code L; Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 Toprim domain [H]
Homologues:
Organism=Homo sapiens, GI19913406, Length=558, Percent_Identity=24.3727598566308, Blast_Score=116, Evalue=9e-26, Organism=Homo sapiens, GI19913408, Length=573, Percent_Identity=23.7347294938918, Blast_Score=115, Evalue=2e-25, Organism=Escherichia coli, GI48994957, Length=820, Percent_Identity=59.2682926829268, Blast_Score=953, Evalue=0.0, Organism=Escherichia coli, GI1789408, Length=561, Percent_Identity=37.6114081996435, Blast_Score=371, Evalue=1e-104, Organism=Caenorhabditis elegans, GI17535065, Length=604, Percent_Identity=24.0066225165563, Blast_Score=122, Evalue=8e-28, Organism=Caenorhabditis elegans, GI212645845, Length=519, Percent_Identity=24.0847784200385, Blast_Score=106, Evalue=5e-23, Organism=Caenorhabditis elegans, GI212645657, Length=155, Percent_Identity=30.9677419354839, Blast_Score=71, Evalue=3e-12, Organism=Saccharomyces cerevisiae, GI6324241, Length=611, Percent_Identity=24.0589198036007, Blast_Score=111, Evalue=6e-25, Organism=Drosophila melanogaster, GI17136538, Length=554, Percent_Identity=23.4657039711191, Blast_Score=111, Evalue=2e-24,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003594 - InterPro: IPR011557 - InterPro: IPR020568 - InterPro: IPR014721 - InterPro: IPR001241 - InterPro: IPR013759 - InterPro: IPR002288 - InterPro: IPR013506 - InterPro: IPR013760 - InterPro: IPR018522 - InterPro: IPR006171 [H]
Pfam domain/function: PF00204 DNA_gyraseB; PF00986 DNA_gyraseB_C; PF02518 HATPase_c; PF01751 Toprim [H]
EC number: =5.99.1.3 [H]
Molecular weight: Translated: 91040; Mature: 90909
Theoretical pI: Translated: 6.10; Mature: 6.10
Prosite motif: PS00177 TOPOISOMERASE_II
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.9 %Cys (Translated Protein) 2.7 %Met (Translated Protein) 3.5 %Cys+Met (Translated Protein) 0.9 %Cys (Mature Protein) 2.6 %Met (Mature Protein) 3.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTEQHNSQPENSYGASSIQILEGLEAVRKRPGMYIGDTSDGTGLHHLVFEVLDNSIDEAL CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHH AGYCNDIHVTIHADNSISVTDNGRGIPTDVKLNDKHEPKRSAAEIVMTELHAGGKFDQNS HHCCCEEEEEEEECCEEEECCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHCCCCCCCCC YKVSGGLHGVGVSCVNALSSWLRLTVRRDGKKHFMEFHRGIAQNRVLEERDGEQVSPMQV EEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHCCCCCCCCCEE IGDTENRGTEVHFMADSTIFGTVEYHYDILAKRIRELSFLNNGVRIRLTDQRSGKEDDFA ECCCCCCCCEEEEEECCEEEEEHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCC FAGGVKGFVEYINKTKSVLHPTIFHINGEKDGVGVEVAMQWNDSYNENVLCFTNNIPQRD HHCHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCEEEEEEECCCCCCCEEEEECCCCCCC GGTHLTGLRAAMTRVINKYIADNEIAKKAKVETSGDDMREGLSCVLSVKVPEPKFSSQTK CCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHCEEEEEEECCCCCCCCHHH DKLVSSEVRAPVEEVVAKALEEFLLETPNDAKIICGKIVEAARARDAARKAREMTRRKGV HHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC LDGVGLPGKLADCQEKDPAKSEIYIVEGDSAGGSAKQGRDRKFQAILPLRGKVLNVEKAR CCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEECCCCCCEEECHHHH YDKLLSSEQIVTLVTALGCGIGKDDYNLDKLRYHRIIIMTDADVDGAHIRTLLLTFFYRQ HHHHHCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHH MPEMIERGYVYIAQPPLYKVKAGRDERYLKDDTELNAHMLRLALQGSELVPTENGTPISG HHHHHHCCEEEEECCCCEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCH DALGELARSYLLARGVVERLSRLYDPAALEAVMDGVAIDLSSEASTEASAKALAAMLSDD HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHCCC SKTEVRVVPAYDAVREQRSLRVERTHHGNVRVSVIDEEFQHTADYQQLVNTANTFKGLIG CCCEEEEEECHHHHHHHHHCEEEEECCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHH AGAAIKRGERSSNVADFKEAMKWLMADAERNMSKQRYKGLGEMNPEQLWETTMDPAVRRL CCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH LRVQIEDAIAADGIFTTLMGDEVEPRRAFIENNALRAGNIDV HHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHCCCCCCCCCCC >Mature Secondary Structure TEQHNSQPENSYGASSIQILEGLEAVRKRPGMYIGDTSDGTGLHHLVFEVLDNSIDEAL CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHH AGYCNDIHVTIHADNSISVTDNGRGIPTDVKLNDKHEPKRSAAEIVMTELHAGGKFDQNS HHCCCEEEEEEEECCEEEECCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHCCCCCCCCC YKVSGGLHGVGVSCVNALSSWLRLTVRRDGKKHFMEFHRGIAQNRVLEERDGEQVSPMQV EEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHCCCCCCCCCEE IGDTENRGTEVHFMADSTIFGTVEYHYDILAKRIRELSFLNNGVRIRLTDQRSGKEDDFA ECCCCCCCCEEEEEECCEEEEEHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCC FAGGVKGFVEYINKTKSVLHPTIFHINGEKDGVGVEVAMQWNDSYNENVLCFTNNIPQRD HHCHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCEEEEEEECCCCCCCEEEEECCCCCCC GGTHLTGLRAAMTRVINKYIADNEIAKKAKVETSGDDMREGLSCVLSVKVPEPKFSSQTK CCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHCEEEEEEECCCCCCCCHHH DKLVSSEVRAPVEEVVAKALEEFLLETPNDAKIICGKIVEAARARDAARKAREMTRRKGV HHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC LDGVGLPGKLADCQEKDPAKSEIYIVEGDSAGGSAKQGRDRKFQAILPLRGKVLNVEKAR CCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEECCCCCCEEECHHHH YDKLLSSEQIVTLVTALGCGIGKDDYNLDKLRYHRIIIMTDADVDGAHIRTLLLTFFYRQ HHHHHCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHH MPEMIERGYVYIAQPPLYKVKAGRDERYLKDDTELNAHMLRLALQGSELVPTENGTPISG HHHHHHCCEEEEECCCCEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCH DALGELARSYLLARGVVERLSRLYDPAALEAVMDGVAIDLSSEASTEASAKALAAMLSDD HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHCCC SKTEVRVVPAYDAVREQRSLRVERTHHGNVRVSVIDEEFQHTADYQQLVNTANTFKGLIG CCCEEEEEECHHHHHHHHHCEEEEECCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHH AGAAIKRGERSSNVADFKEAMKWLMADAERNMSKQRYKGLGEMNPEQLWETTMDPAVRRL CCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH LRVQIEDAIAADGIFTTLMGDEVEPRRAFIENNALRAGNIDV HHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 1906260 [H]