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The map label for this gene is hemA [H]

Identifier: 161723170

GI number: 161723170

Start: 3367091

End: 3368389

Strand: Direct

Name: hemA [H]

Synonym: BTH_I2929

Alternate gene names: 161723170

Gene position: 3367091-3368389 (Clockwise)

Preceding gene: 83718401

Following gene: 83720975

Centisome position: 88.39

GC content: 68.9

Gene sequence:

>1299_bases
ATGCAGCTCCTCACGATCGGAATCAACCACCACACTGCGCCTGTCGCCTTGCGCGAACGCGTGGCGTTTCCGCTCGAACA
GATCAAGCCCGCATTGTCGACGTTCAAGAGCGTCTTCCTCGGCCATCCGGCGCCGAACGCGCCCGAGGCGGCGATCCTGT
CGACCTGCAATCGCACCGAGCTGTACTGCGCGACCGACGATCGCGCGGCGCGCGACGCGGCGATCCGCTGGATGTCCGAC
TACCACCGGATTCCCGCCGACGAGCTCGCGCCGCACGTGTACGCGCTGCCGCAATCCGAGGCGGTGCGCCACGCGTTTCG
CGTCGCCTCCGGGCTCGATTCGATGGTGCTCGGCGAAACGCAGATCCTCGGCCAGATGAAGAACGCGGTGCGCACCGCGT
CCGAGGCGGGCTCGCTCGGCACCTACCTGAACCAGCTGTTCCAGCGCACGTTCGCGGTCGCGAAGGAAGTGCGCGGCACG
ACCGAGATCGGCGCGCAGTCGGTGTCGATGGCGGCCGCGGCCGTGCGGCTCGCGCAGCGGATCTTCGAGCAGGTCGCGCA
GCAGCGCGTGCTGTTCATCGGCGCGGGCGAGATGATCGAGCTCTGCGCGACGCACTTCGCCGCGCAAGGCCCGCGCGAGC
TCGTCGTCGCGAACCGCACCGCCGAGCGCGGCGCGAAGCTCGCCGAACGGTTCGGCGGCCGTGCGATGCCGCTTTCCGAT
CTGCCCGCACGGATGCACGAATTCGACATCATCGTGTCGTGCACCGCGTCGACGCTGCCGATCATCGGCCTCGGCGCCGT
CGAGCGCGCGGTGAAGGCGCGCCGCCACCGGCCGATCTTCATGGTCGACCTCGCGGTGCCGCGCGACATCGAGCCCGAAG
TCGGCAAGCTGAAGGACGTGTTTCTCTATACCGTCGACGATCTCGGCGCGATCGTCCGCGAAGGCAACGCATCGCGGCAG
GCCGCGGTCGCGCAGGCCGAGGCGATCATCGAGACGCGCGTGCAGAATTTCATGCAGTGGCTCGATGCGCGCAGCATCGT
GCCCGTGATCCGCCACATGCACACGCAAGCCGACGCGCTGCGCCGCGCGGAACTCGAGCGCGCACGCAAGATGCTCGCGC
GCGGCGACGATCCGGCGGCCGTGCTCGACGCGCTGTCGCAGGCGCTCACCAACAAGCTGATTCACGGCCCGACGAGCGCG
CTCAACCGCGCGAACGGCGCCGATCGCGATTCGCTGATCGACCTGATGCGCGGTTTCTACCAGCACGCGCCCCGCTCGTC
GGACACGTCGGACCATTAG

Upstream 100 bases:

>100_bases
GATCGTCCACACGGGCCGCGTGGACGGGCCGCGACACGCGCCGACCATGGATTTGTCGTCGAAACGCTATAATATGGGAC
TAAACGATAGCCTCTTGGAC

Downstream 100 bases:

>100_bases
CGGCGCCCGGCCTGCCCGCCCCTTCCTTTCCCTTTTCGAATTCTTCCCTGGGAGCATCGCTCCGCACCATGAAGACGAGC
ATGCAAAGCAAGCTCGACCA

Product: glutamyl-tRNA reductase

Products: NA

Alternate protein names: GluTR [H]

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MQLLTIGINHHTAPVALRERVAFPLEQIKPALSTFKSVFLGHPAPNAPEAAILSTCNRTELYCATDDRAARDAAIRWMSD
YHRIPADELAPHVYALPQSEAVRHAFRVASGLDSMVLGETQILGQMKNAVRTASEAGSLGTYLNQLFQRTFAVAKEVRGT
TEIGAQSVSMAAAAVRLAQRIFEQVAQQRVLFIGAGEMIELCATHFAAQGPRELVVANRTAERGAKLAERFGGRAMPLSD
LPARMHEFDIIVSCTASTLPIIGLGAVERAVKARRHRPIFMVDLAVPRDIEPEVGKLKDVFLYTVDDLGAIVREGNASRQ
AAVAQAEAIIETRVQNFMQWLDARSIVPVIRHMHTQADALRRAELERARKMLARGDDPAAVLDALSQALTNKLIHGPTSA
LNRANGADRDSLIDLMRGFYQHAPRSSDTSDH

Sequences:

>Translated_432_residues
MQLLTIGINHHTAPVALRERVAFPLEQIKPALSTFKSVFLGHPAPNAPEAAILSTCNRTELYCATDDRAARDAAIRWMSD
YHRIPADELAPHVYALPQSEAVRHAFRVASGLDSMVLGETQILGQMKNAVRTASEAGSLGTYLNQLFQRTFAVAKEVRGT
TEIGAQSVSMAAAAVRLAQRIFEQVAQQRVLFIGAGEMIELCATHFAAQGPRELVVANRTAERGAKLAERFGGRAMPLSD
LPARMHEFDIIVSCTASTLPIIGLGAVERAVKARRHRPIFMVDLAVPRDIEPEVGKLKDVFLYTVDDLGAIVREGNASRQ
AAVAQAEAIIETRVQNFMQWLDARSIVPVIRHMHTQADALRRAELERARKMLARGDDPAAVLDALSQALTNKLIHGPTSA
LNRANGADRDSLIDLMRGFYQHAPRSSDTSDH
>Mature_432_residues
MQLLTIGINHHTAPVALRERVAFPLEQIKPALSTFKSVFLGHPAPNAPEAAILSTCNRTELYCATDDRAARDAAIRWMSD
YHRIPADELAPHVYALPQSEAVRHAFRVASGLDSMVLGETQILGQMKNAVRTASEAGSLGTYLNQLFQRTFAVAKEVRGT
TEIGAQSVSMAAAAVRLAQRIFEQVAQQRVLFIGAGEMIELCATHFAAQGPRELVVANRTAERGAKLAERFGGRAMPLSD
LPARMHEFDIIVSCTASTLPIIGLGAVERAVKARRHRPIFMVDLAVPRDIEPEVGKLKDVFLYTVDDLGAIVREGNASRQ
AAVAQAEAIIETRVQNFMQWLDARSIVPVIRHMHTQADALRRAELERARKMLARGDDPAAVLDALSQALTNKLIHGPTSA
LNRANGADRDSLIDLMRGFYQHAPRSSDTSDH

Specific function: Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) [H]

COG id: COG0373

COG function: function code H; Glutamyl-tRNA reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamyl-tRNA reductase family [H]

Homologues:

Organism=Escherichia coli, GI1787461, Length=405, Percent_Identity=45.9259259259259, Blast_Score=348, Evalue=4e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000343
- InterPro:   IPR015896
- InterPro:   IPR015895
- InterPro:   IPR016040
- InterPro:   IPR018214
- InterPro:   IPR006151 [H]

Pfam domain/function: PF00745 GlutR_dimer; PF05201 GlutR_N; PF01488 Shikimate_DH [H]

EC number: =1.2.1.70 [H]

Molecular weight: Translated: 47268; Mature: 47268

Theoretical pI: Translated: 8.36; Mature: 8.36

Prosite motif: PS00747 GLUTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLLTIGINHHTAPVALRERVAFPLEQIKPALSTFKSVFLGHPAPNAPEAAILSTCNRTE
CEEEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCE
LYCATDDRAARDAAIRWMSDYHRIPADELAPHVYALPQSEAVRHAFRVASGLDSMVLGET
EEEECCCHHHHHHHHHHHHHHHCCCHHHHCCCEEECCCHHHHHHHHHHHHCCHHHHHHHH
QILGQMKNAVRTASEAGSLGTYLNQLFQRTFAVAKEVRGTTEIGAQSVSMAAAAVRLAQR
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
IFEQVAQQRVLFIGAGEMIELCATHFAAQGPRELVVANRTAERGAKLAERFGGRAMPLSD
HHHHHHHHHEEEECCHHHHHHHHHHHHCCCCHHEEEECCCHHHHHHHHHHHCCCCCCHHH
LPARMHEFDIIVSCTASTLPIIGLGAVERAVKARRHRPIFMVDLAVPRDIEPEVGKLKDV
HHHHHHHHHEEEEECCCCCCEEEHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHH
FLYTVDDLGAIVREGNASRQAAVAQAEAIIETRVQNFMQWLDARSIVPVIRHMHTQADAL
HEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRAELERARKMLARGDDPAAVLDALSQALTNKLIHGPTSALNRANGADRDSLIDLMRGFY
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHH
QHAPRSSDTSDH
HHCCCCCCCCCC
>Mature Secondary Structure
MQLLTIGINHHTAPVALRERVAFPLEQIKPALSTFKSVFLGHPAPNAPEAAILSTCNRTE
CEEEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCE
LYCATDDRAARDAAIRWMSDYHRIPADELAPHVYALPQSEAVRHAFRVASGLDSMVLGET
EEEECCCHHHHHHHHHHHHHHHCCCHHHHCCCEEECCCHHHHHHHHHHHHCCHHHHHHHH
QILGQMKNAVRTASEAGSLGTYLNQLFQRTFAVAKEVRGTTEIGAQSVSMAAAAVRLAQR
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
IFEQVAQQRVLFIGAGEMIELCATHFAAQGPRELVVANRTAERGAKLAERFGGRAMPLSD
HHHHHHHHHEEEECCHHHHHHHHHHHHCCCCHHEEEECCCHHHHHHHHHHHCCCCCCHHH
LPARMHEFDIIVSCTASTLPIIGLGAVERAVKARRHRPIFMVDLAVPRDIEPEVGKLKDV
HHHHHHHHHEEEEECCCCCCEEEHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHH
FLYTVDDLGAIVREGNASRQAAVAQAEAIIETRVQNFMQWLDARSIVPVIRHMHTQADAL
HEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRAELERARKMLARGDDPAAVLDALSQALTNKLIHGPTSALNRANGADRDSLIDLMRGFY
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHH
QHAPRSSDTSDH
HHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA