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The map label for this gene is yacO [H]

Identifier: 83591297

GI number: 83591297

Start: 2587933

End: 2588673

Strand: Reverse

Name: yacO [H]

Synonym: Moth_2481

Alternate gene names: 83591297

Gene position: 2588673-2587933 (Counterclockwise)

Preceding gene: 83591298

Following gene: 83591296

Centisome position: 98.47

GC content: 65.45

Gene sequence:

>741_bases
ATGACCGAGACTCTGGCCGGCCGTAACCAGGTCCGGGAAGCCCTGCGGGCCGGTCGGCCCCTGAACAAGATTTTACTGGC
TCCCCACCTGGAAGGTCAGGCCATCGGAGAGATTATCAACCTGGCCCGGGAGAGGGGGGTACCCCTGCAGCGGGTCAACA
GGGCCGCCCTGGAGAAGCTGGCTGGCCACCACCACCAGGGGGTAGTGGCCCTGGCCGCGGCCCGGGAGTATGCTGACCTG
GAGGATCTCCTGGCCCGGGCCGGGGAAGCGGGGGAGCCCCCTTTTTTAATTATGCTCGACCGGGTGGAAGACCCCCATAA
CCTGGGAGCTATCCTGCGTTCAGCGGAAGCCGTCGGCGCCCACGGTGTTATTATCCCCCGGCGACGGGGGGTAGGGTTAA
CAGCGGCTGTAGCGCGGGCGGCGGTGGGCGCCCAGGAATACGTACCGGTGGCCCGGGTGACAAACCTGGCCCGGACCCTG
GAGGAGCTTAAGGGTAAGGGGCTCTGGGCCATCGGTGCCGCCGGCGATGCCGGCCAGGAAGCCTTCAACGCAGATTTTAC
TGTGCCCCTGGTCCTGGTTTTAGGCAGCGAAGGCCGGGGCCTCTCACCCCTGGTGCGTTCCCGGTGTGATTTTACAGTGC
ACCTGCCCATGCGGGGCAGGATTAACTCCCTCAATGTGGCTACCGCGGCGACGGTGTTGATGTATGAAGTCTTGCGCCAG
CGTGGCCAGGCCCGGCCTTAA

Upstream 100 bases:

>100_bases
TGAAGATATTAATTACGACCAGAATTTCCCGGGGAAATACTATGCCCGGGTAATTATTACGGATGACTTTTTCCATGAAA
TTGGCCGGGAGGAACTCTAA

Downstream 100 bases:

>100_bases
AGTGGGGGTGCAGCCCATGGACGTTCTGATTGTGGACGGCTATAATTTTTTGCATAACTGGCCAGAATTAACCCGCTTAA
AAGAGTCAAGTTTTGACCAT

Product: RNA methyltransferase TrmH, group 3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MTETLAGRNQVREALRAGRPLNKILLAPHLEGQAIGEIINLARERGVPLQRVNRAALEKLAGHHHQGVVALAAAREYADL
EDLLARAGEAGEPPFLIMLDRVEDPHNLGAILRSAEAVGAHGVIIPRRRGVGLTAAVARAAVGAQEYVPVARVTNLARTL
EELKGKGLWAIGAAGDAGQEAFNADFTVPLVLVLGSEGRGLSPLVRSRCDFTVHLPMRGRINSLNVATAATVLMYEVLRQ
RGQARP

Sequences:

>Translated_246_residues
MTETLAGRNQVREALRAGRPLNKILLAPHLEGQAIGEIINLARERGVPLQRVNRAALEKLAGHHHQGVVALAAAREYADL
EDLLARAGEAGEPPFLIMLDRVEDPHNLGAILRSAEAVGAHGVIIPRRRGVGLTAAVARAAVGAQEYVPVARVTNLARTL
EELKGKGLWAIGAAGDAGQEAFNADFTVPLVLVLGSEGRGLSPLVRSRCDFTVHLPMRGRINSLNVATAATVLMYEVLRQ
RGQARP
>Mature_245_residues
TETLAGRNQVREALRAGRPLNKILLAPHLEGQAIGEIINLARERGVPLQRVNRAALEKLAGHHHQGVVALAAAREYADLE
DLLARAGEAGEPPFLIMLDRVEDPHNLGAILRSAEAVGAHGVIIPRRRGVGLTAAVARAAVGAQEYVPVARVTNLARTLE
ELKGKGLWAIGAAGDAGQEAFNADFTVPLVLVLGSEGRGLSPLVRSRCDFTVHLPMRGRINSLNVATAATVLMYEVLRQR
GQARP

Specific function: Unknown

COG id: COG0566

COG function: function code J; rRNA methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase TrmH family [H]

Homologues:

Organism=Homo sapiens, GI40068479, Length=226, Percent_Identity=32.3008849557522, Blast_Score=92, Evalue=3e-19,
Organism=Escherichia coli, GI1790623, Length=247, Percent_Identity=40.080971659919, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI1790083, Length=171, Percent_Identity=30.9941520467836, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788935, Length=190, Percent_Identity=28.9473684210526, Blast_Score=80, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17555908, Length=258, Percent_Identity=30.2325581395349, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6324775, Length=174, Percent_Identity=28.735632183908, Blast_Score=80, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004441
- InterPro:   IPR001537
- InterPro:   IPR013123 [H]

Pfam domain/function: PF00588 SpoU_methylase; PF08032 SpoU_sub_bind [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 26269; Mature: 26138

Theoretical pI: Translated: 10.32; Mature: 10.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTETLAGRNQVREALRAGRPLNKILLAPHLEGQAIGEIINLARERGVPLQRVNRAALEKL
CCCCCCCHHHHHHHHHCCCCHHHEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHH
AGHHHQGVVALAAAREYADLEDLLARAGEAGEPPFLIMLDRVEDPHNLGAILRSAEAVGA
HCCCCCCHHHHHHHHHHCCHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCC
HGVIIPRRRGVGLTAAVARAAVGAQEYVPVARVTNLARTLEELKGKGLWAIGAAGDAGQE
CCEEEECCCCCCHHHHHHHHHHCHHHHCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHH
AFNADFTVPLVLVLGSEGRGLSPLVRSRCDFTVHLPMRGRINSLNVATAATVLMYEVLRQ
HHCCCCCEEEEEEECCCCCCCCHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
RGQARP
HCCCCC
>Mature Secondary Structure 
TETLAGRNQVREALRAGRPLNKILLAPHLEGQAIGEIINLARERGVPLQRVNRAALEKL
CCCCCCHHHHHHHHHCCCCHHHEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHH
AGHHHQGVVALAAAREYADLEDLLARAGEAGEPPFLIMLDRVEDPHNLGAILRSAEAVGA
HCCCCCCHHHHHHHHHHCCHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCC
HGVIIPRRRGVGLTAAVARAAVGAQEYVPVARVTNLARTLEELKGKGLWAIGAAGDAGQE
CCEEEECCCCCCHHHHHHHHHHCHHHHCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHH
AFNADFTVPLVLVLGSEGRGLSPLVRSRCDFTVHLPMRGRINSLNVATAATVLMYEVLRQ
HHCCCCCEEEEEEECCCCCCCCHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
RGQARP
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 7510287; 3145906 [H]