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The map label for this gene is thyX [H]

Identifier: 83591298

GI number: 83591298

Start: 2588674

End: 2589372

Strand: Reverse

Name: thyX [H]

Synonym: Moth_2482

Alternate gene names: 83591298

Gene position: 2589372-2588674 (Counterclockwise)

Preceding gene: 83591299

Following gene: 83591297

Centisome position: 98.5

GC content: 48.78

Gene sequence:

>699_bases
ATGATAATTGAACAACCCCGGGTACTTGTACCCGAAAAGGCCCTAGATGCCAACCTTATCTTAAGGCTCGAGCGTTACGC
CCGGGTCTGCTATAAATCTGAAGCCAGAACTGGGGCGGATACGGCCGCCCCTTTTTTAAAAAAGCTCCTTGAACGGGGCC
ACGAATCAGTTATTGAGCACGAGAAGATCACCGTTTTGATCATTGCCGACCGGGGTATATCCCATGAAATTGTCAGGCAC
CGCATTGGATCTTACAGCCAGGAATCGACCAGGTATTGCAACTATAGTAAAGATAGCTTTGGCAACGAGATAACGGTTAT
CGAGCCCTTCTTTTTCGCCGGCAGGGAAGCTTATAATCTATGGGAAAAAGCCTGTCGGGTTGCCGAGAAGAGCTACCTGG
AGTTACTAAAGTATAGCTCGCCCCAGGAAGCGCGCTCTGTCCTCCCCAATTCCCTAAAAACCGAGCTGGTCGTTACGTAC
AATTTAAGGGAATGGCGGCATTTTTTCCGCCTGCGCTGCTCCAGTTCGGCCCACCCCCAAATGCGACAGATAGCCATACC
GCTACTGTTGCTTTTCAGGAAGAGATTGCCTGTGCTATTTGAAGATATTAATTACGACCAGAATTTCCCGGGGAAATACT
ATGCCCGGGTAATTATTACGGATGACTTTTTCCATGAAATTGGCCGGGAGGAACTCTAA

Upstream 100 bases:

>100_bases
AGGAACTGGCGCACCTGATTTTTAAACTGGCGGAACAAGACTAAAGGGACTAATTACCACCGGCGAGAGTAAAGACCGCC
TGGCGGGAGTGGAAGAGACA

Downstream 100 bases:

>100_bases
ATGACCGAGACTCTGGCCGGCCGTAACCAGGTCCGGGAAGCCCTGCGGGCCGGTCGGCCCCTGAACAAGATTTTACTGGC
TCCCCACCTGGAAGGTCAGG

Product: thymidylate synthase complementing protein ThyX

Products: NA

Alternate protein names: TS; TSase [H]

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MIIEQPRVLVPEKALDANLILRLERYARVCYKSEARTGADTAAPFLKKLLERGHESVIEHEKITVLIIADRGISHEIVRH
RIGSYSQESTRYCNYSKDSFGNEITVIEPFFFAGREAYNLWEKACRVAEKSYLELLKYSSPQEARSVLPNSLKTELVVTY
NLREWRHFFRLRCSSSAHPQMRQIAIPLLLLFRKRLPVLFEDINYDQNFPGKYYARVIITDDFFHEIGREEL

Sequences:

>Translated_232_residues
MIIEQPRVLVPEKALDANLILRLERYARVCYKSEARTGADTAAPFLKKLLERGHESVIEHEKITVLIIADRGISHEIVRH
RIGSYSQESTRYCNYSKDSFGNEITVIEPFFFAGREAYNLWEKACRVAEKSYLELLKYSSPQEARSVLPNSLKTELVVTY
NLREWRHFFRLRCSSSAHPQMRQIAIPLLLLFRKRLPVLFEDINYDQNFPGKYYARVIITDDFFHEIGREEL
>Mature_232_residues
MIIEQPRVLVPEKALDANLILRLERYARVCYKSEARTGADTAAPFLKKLLERGHESVIEHEKITVLIIADRGISHEIVRH
RIGSYSQESTRYCNYSKDSFGNEITVIEPFFFAGREAYNLWEKACRVAEKSYLELLKYSSPQEARSVLPNSLKTELVVTY
NLREWRHFFRLRCSSSAHPQMRQIAIPLLLLFRKRLPVLFEDINYDQNFPGKYYARVIITDDFFHEIGREEL

Specific function: Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate [H]

COG id: COG1351

COG function: function code F; Predicted alternative thymidylate synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thyX (flavin-dependent thymidylate synthase) domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003669 [H]

Pfam domain/function: PF02511 Thy1 [H]

EC number: =2.1.1.148 [H]

Molecular weight: Translated: 27218; Mature: 27218

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: PS00014 ER_TARGET

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIEQPRVLVPEKALDANLILRLERYARVCYKSEARTGADTAAPFLKKLLERGHESVIEH
CCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCC
EKITVLIIADRGISHEIVRHRIGSYSQESTRYCNYSKDSFGNEITVIEPFFFAGREAYNL
CCEEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCHHHCCHHHHHH
WEKACRVAEKSYLELLKYSSPQEARSVLPNSLKTELVVTYNLREWRHFFRLRCSSSAHPQ
HHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHCCCCCCHH
MRQIAIPLLLLFRKRLPVLFEDINYDQNFPGKYYARVIITDDFFHEIGREEL
HHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCEEEEEEEEHHHHHHCCCCCC
>Mature Secondary Structure
MIIEQPRVLVPEKALDANLILRLERYARVCYKSEARTGADTAAPFLKKLLERGHESVIEH
CCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCC
EKITVLIIADRGISHEIVRHRIGSYSQESTRYCNYSKDSFGNEITVIEPFFFAGREAYNL
CCEEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCHHHCCHHHHHH
WEKACRVAEKSYLELLKYSSPQEARSVLPNSLKTELVVTYNLREWRHFFRLRCSSSAHPQ
HHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHCCCCCCHH
MRQIAIPLLLLFRKRLPVLFEDINYDQNFPGKYYARVIITDDFFHEIGREEL
HHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCEEEEEEEEHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA