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The map label for this gene is rlmH

Identifier: 83591232

GI number: 83591232

Start: 2539156

End: 2539638

Strand: Reverse

Name: rlmH

Synonym: Moth_2416

Alternate gene names: 83591232

Gene position: 2539638-2539156 (Counterclockwise)

Preceding gene: 83591233

Following gene: 83591231

Centisome position: 96.61

GC content: 57.35

Gene sequence:

>483_bases
ATGTTACACCTTACCATCGTCGCCGTCGGCCGGGTGCGGGAGAAATACCTGGTCGCCGGGATTGAAGAATATCTGAAGCG
TCTGCGGCCCTATGCCCGCGTGCGTATCCTGGAGGCTCCCGAGGAGAAGGTGCCCGATAAACCCTCACCCGCTGGGGTCG
AGCAAATCTTGGCCAGCGAAGGCCGGGGTATAGGAAGGCTGATACCTCCCAGCAGTTTTACCGTAGCCCTGGACCGGGAG
GGGGTAATGCTATCCTCGGAAGAACTGGCCGGCAGGCTGGCGGATCTGGCCCTGGCTGGAAAAAACGAAGTAGCCCTGAT
TATCGGCGGTACCCTGGGTCTGGCAACATTTATCCTTCAACAAGCTGATCTACGCCTCTCTTTTTCCCGCTTTACCTTCC
CCCACCAGCTTATGCGCCTGATACTCCTGGAGCAATTGTACCGGGCCTTCAAAATCCAGCGGGGTGAAACTTACCACCGT
TAA

Upstream 100 bases:

>100_bases
CCCAAATTTTTGGCAAAATCCTATTGGCAAGGAACGGCGGGGGGACATACCCCGTCTATAAAGAAGAACCAATTATACCG
GAGAAACCCCGGAGGTACCA

Downstream 100 bases:

>100_bases
AACCGTACATGACGGTGATTTTTTTGGTCATAATACTTCCTGGATATGTTTACCAGGGAGGCCAGAATACTCTTGACGAG
GCACTACCGTTACCTGCAGC

Product: hypothetical protein

Products: NA

Alternate protein names: 23S rRNA m3Psi1915 methyltransferase; rRNA (pseudouridine-N3-)-methyltransferase rlmH

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MLHLTIVAVGRVREKYLVAGIEEYLKRLRPYARVRILEAPEEKVPDKPSPAGVEQILASEGRGIGRLIPPSSFTVALDRE
GVMLSSEELAGRLADLALAGKNEVALIIGGTLGLATFILQQADLRLSFSRFTFPHQLMRLILLEQLYRAFKIQRGETYHR

Sequences:

>Translated_160_residues
MLHLTIVAVGRVREKYLVAGIEEYLKRLRPYARVRILEAPEEKVPDKPSPAGVEQILASEGRGIGRLIPPSSFTVALDRE
GVMLSSEELAGRLADLALAGKNEVALIIGGTLGLATFILQQADLRLSFSRFTFPHQLMRLILLEQLYRAFKIQRGETYHR
>Mature_160_residues
MLHLTIVAVGRVREKYLVAGIEEYLKRLRPYARVRILEAPEEKVPDKPSPAGVEQILASEGRGIGRLIPPSSFTVALDRE
GVMLSSEELAGRLADLALAGKNEVALIIGGTLGLATFILQQADLRLSFSRFTFPHQLMRLILLEQLYRAFKIQRGETYHR

Specific function: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA

COG id: COG1576

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase rlmH family

Homologues:

Organism=Escherichia coli, GI1786855, Length=165, Percent_Identity=32.1212121212121, Blast_Score=73, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RLMH_MOOTA (Q2RFU1)

Other databases:

- EMBL:   CP000232
- RefSeq:   YP_431241.1
- ProteinModelPortal:   Q2RFU1
- SMR:   Q2RFU1
- STRING:   Q2RFU1
- GeneID:   3832167
- GenomeReviews:   CP000232_GR
- KEGG:   mta:Moth_2416
- NMPDR:   fig|264732.9.peg.2448
- eggNOG:   COG1576
- HOGENOM:   HBG622807
- OMA:   TANHPYH
- PhylomeDB:   Q2RFU1
- BioCyc:   MTHE264732:MOTH_2416-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00658
- InterPro:   IPR003742
- PIRSF:   PIRSF004505

Pfam domain/function: PF02590 SPOUT_MTase

EC number: NA

Molecular weight: Translated: 17894; Mature: 17894

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHLTIVAVGRVREKYLVAGIEEYLKRLRPYARVRILEAPEEKVPDKPSPAGVEQILASE
CEEEEEEEHHHHHHHHHHHHHHHHHHHHCHHHEEEEEECCHHHCCCCCCCHHHHHHHHHC
GRGIGRLIPPSSFTVALDREGVMLSSEELAGRLADLALAGKNEVALIIGGTLGLATFILQ
CCCCCCCCCCCCEEEEECCCCCEECHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHH
QADLRLSFSRFTFPHQLMRLILLEQLYRAFKIQRGETYHR
HHCCEEEHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MLHLTIVAVGRVREKYLVAGIEEYLKRLRPYARVRILEAPEEKVPDKPSPAGVEQILASE
CEEEEEEEHHHHHHHHHHHHHHHHHHHHCHHHEEEEEECCHHHCCCCCCCHHHHHHHHHC
GRGIGRLIPPSSFTVALDREGVMLSSEELAGRLADLALAGKNEVALIIGGTLGLATFILQ
CCCCCCCCCCCCEEEEECCCCCEECHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHH
QADLRLSFSRFTFPHQLMRLILLEQLYRAFKIQRGETYHR
HHCCEEEHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA