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The map label for this gene is argD [H]

Identifier: 83591108

GI number: 83591108

Start: 2399142

End: 2400350

Strand: Reverse

Name: argD [H]

Synonym: Moth_2287

Alternate gene names: 83591108

Gene position: 2400350-2399142 (Counterclockwise)

Preceding gene: 83591109

Following gene: 83591107

Centisome position: 91.31

GC content: 63.03

Gene sequence:

>1209_bases
ATGGATAATGCGGCTATTGTGTCCAGGGGAGAGAAATATGTTATGCGGACTTACGGGCGCTACCCCATGGCCCTGGTCCG
GGGTGAGGGCGCCCGGGTCTGGGATGCCGACGGCAAGGAGTACCTGGACTTTGTCAGCGGCCTGGCCGTCAATTCCCTGG
GTCACTGCCATCCCCGGGTGGTGGAGGCCATCCGGGAGCAGGCCGGCAGGCTCATCCACTGCTCCAACCTCTACTGGATC
GAACCCCAGGTGGAGCTGGCCCGCCTGCTGGTGGAGAACTCGGCCCTGGATAAAGTCTTTTTCTGTAACAGCGGCGCCGA
GGCCAACGAGGCTGCCATCAAACTGGCCCGCAAATATGCCAAGGAACACCGGGGGCCGGAGAGCTATGAGATAATAACCA
TGCGCCGTTCCTTCCACGGCCGCACCCTGGCCACCCTGACGGCCACCGGCCAGGAGAAATTCCACCACGGCTTTGCTCCC
CTGCCGCCGGGGTTTAGATACGCCCCCTTCAACGACCTCTCCAGCCTGCGGGCGGCGGTCGGTCCCCGCACCTGCGCCGT
CATGCTGGAACCGGTCCAGGGGGAAGGCGGCGTCTACGCGGCTAATAAGGATTACCTCCAGGCCGTACGCGCCCTCTGCG
ACGACGAAGGGCTCCTGTTGATCTTTGATGAAGTCCAATGCGGCCTGGGCCGGACGGGATATCTCTTCGCCTACCAGTAT
TACGAGGTCGAGCCTGATATCCTGACCCTGGCCAAGGCCCTGGCCGGCGGTGTGCCCATCGGTGCCATGCTGGCTAAAGA
AAGAGCGGCTTCTGCCTTTGCCCCCGGGGACCACGCCTCCACCTTCGGCGGCAACCCCCTGGCGACGGCGGCCGGCGTGG
CGGCCTTTAAGGCCCTCCTGCAAGAAGGGCTGGTGGAGAATGCCCGGGTGCTGGGGCAGTATTTTTACCAGCAATTAGAA
GGGCTGGTCCGGGAGTTCCCGCAGCTCATCGAGGTGCGGGGCCGTGGTCTCCTGCTGGGGGTAGAGATTGACGGTCCGGC
AGGAGAGGTGGTGGCGGCCTGCCAGGAGCGGGGCCTTTTAATCAACTCCCTCCATGGTCACGTCCTCCGCTTCCTGCCGC
CTTTAATAGTCACCCGGGAGGACATTGACCGGGCGGTGACCATTTTAAAAGAAGCGTTGCACGAAGTACTGGGGCAGGGG
CAGAAATAA

Upstream 100 bases:

>100_bases
TACCGGGGTGGGGACTATGGTTGTTCCGGGGTAAATATCAGCTTGTCTAAAAAACTAATTGGGCAAGGACTAAAACAATA
TATCAGGAGGTGGCCGGAAA

Downstream 100 bases:

>100_bases
GGCGGGCGCCCGCCATAGTTTTTGGTTTTAGGTACGGCGGGAAAATATAGTGGCAAAAATTACGGGTTTTCAAGTAAAAT
AAGGAATGTAAATAAGGAAA

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MDNAAIVSRGEKYVMRTYGRYPMALVRGEGARVWDADGKEYLDFVSGLAVNSLGHCHPRVVEAIREQAGRLIHCSNLYWI
EPQVELARLLVENSALDKVFFCNSGAEANEAAIKLARKYAKEHRGPESYEIITMRRSFHGRTLATLTATGQEKFHHGFAP
LPPGFRYAPFNDLSSLRAAVGPRTCAVMLEPVQGEGGVYAANKDYLQAVRALCDDEGLLLIFDEVQCGLGRTGYLFAYQY
YEVEPDILTLAKALAGGVPIGAMLAKERAASAFAPGDHASTFGGNPLATAAGVAAFKALLQEGLVENARVLGQYFYQQLE
GLVREFPQLIEVRGRGLLLGVEIDGPAGEVVAACQERGLLINSLHGHVLRFLPPLIVTREDIDRAVTILKEALHEVLGQG
QK

Sequences:

>Translated_402_residues
MDNAAIVSRGEKYVMRTYGRYPMALVRGEGARVWDADGKEYLDFVSGLAVNSLGHCHPRVVEAIREQAGRLIHCSNLYWI
EPQVELARLLVENSALDKVFFCNSGAEANEAAIKLARKYAKEHRGPESYEIITMRRSFHGRTLATLTATGQEKFHHGFAP
LPPGFRYAPFNDLSSLRAAVGPRTCAVMLEPVQGEGGVYAANKDYLQAVRALCDDEGLLLIFDEVQCGLGRTGYLFAYQY
YEVEPDILTLAKALAGGVPIGAMLAKERAASAFAPGDHASTFGGNPLATAAGVAAFKALLQEGLVENARVLGQYFYQQLE
GLVREFPQLIEVRGRGLLLGVEIDGPAGEVVAACQERGLLINSLHGHVLRFLPPLIVTREDIDRAVTILKEALHEVLGQG
QK
>Mature_402_residues
MDNAAIVSRGEKYVMRTYGRYPMALVRGEGARVWDADGKEYLDFVSGLAVNSLGHCHPRVVEAIREQAGRLIHCSNLYWI
EPQVELARLLVENSALDKVFFCNSGAEANEAAIKLARKYAKEHRGPESYEIITMRRSFHGRTLATLTATGQEKFHHGFAP
LPPGFRYAPFNDLSSLRAAVGPRTCAVMLEPVQGEGGVYAANKDYLQAVRALCDDEGLLLIFDEVQCGLGRTGYLFAYQY
YEVEPDILTLAKALAGGVPIGAMLAKERAASAFAPGDHASTFGGNPLATAAGVAAFKALLQEGLVENARVLGQYFYQQLE
GLVREFPQLIEVRGRGLLLGVEIDGPAGEVVAACQERGLLINSLHGHVLRFLPPLIVTREDIDRAVTILKEALHEVLGQG
QK

Specific function: Involved In Both The Arginine And Lysine Biosynthetic Pathways. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=396, Percent_Identity=37.1212121212121, Blast_Score=266, Evalue=2e-71,
Organism=Homo sapiens, GI284507298, Length=299, Percent_Identity=38.7959866220736, Blast_Score=209, Evalue=4e-54,
Organism=Homo sapiens, GI13994255, Length=439, Percent_Identity=31.6628701594533, Blast_Score=192, Evalue=5e-49,
Organism=Homo sapiens, GI37574042, Length=421, Percent_Identity=28.5035629453682, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI24119277, Length=417, Percent_Identity=27.5779376498801, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI226442705, Length=421, Percent_Identity=27.5534441805226, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI226442709, Length=390, Percent_Identity=28.4615384615385, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI188536080, Length=403, Percent_Identity=23.8213399503722, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI38679950, Length=403, Percent_Identity=23.8213399503722, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI38679946, Length=403, Percent_Identity=23.8213399503722, Blast_Score=91, Evalue=1e-18,
Organism=Escherichia coli, GI1789759, Length=392, Percent_Identity=44.6428571428571, Blast_Score=346, Evalue=2e-96,
Organism=Escherichia coli, GI1788044, Length=396, Percent_Identity=42.4242424242424, Blast_Score=337, Evalue=7e-94,
Organism=Escherichia coli, GI145693181, Length=377, Percent_Identity=40.5835543766578, Blast_Score=246, Evalue=1e-66,
Organism=Escherichia coli, GI1789016, Length=426, Percent_Identity=34.5070422535211, Blast_Score=233, Evalue=1e-62,
Organism=Escherichia coli, GI1787560, Length=400, Percent_Identity=36, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI1786349, Length=304, Percent_Identity=34.8684210526316, Blast_Score=142, Evalue=6e-35,
Organism=Escherichia coli, GI1786991, Length=404, Percent_Identity=30.1980198019802, Blast_Score=141, Evalue=7e-35,
Organism=Caenorhabditis elegans, GI25144271, Length=401, Percent_Identity=36.1596009975062, Blast_Score=276, Evalue=1e-74,
Organism=Caenorhabditis elegans, GI32564660, Length=436, Percent_Identity=33.7155963302752, Blast_Score=230, Evalue=1e-60,
Organism=Caenorhabditis elegans, GI25144274, Length=399, Percent_Identity=31.8295739348371, Blast_Score=221, Evalue=4e-58,
Organism=Caenorhabditis elegans, GI71992977, Length=429, Percent_Identity=30.3030303030303, Blast_Score=170, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI71981843, Length=180, Percent_Identity=32.7777777777778, Blast_Score=118, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI17541228, Length=452, Percent_Identity=24.7787610619469, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71992985, Length=106, Percent_Identity=36.7924528301887, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324432, Length=400, Percent_Identity=35.25, Blast_Score=269, Evalue=5e-73,
Organism=Saccharomyces cerevisiae, GI6323470, Length=406, Percent_Identity=36.4532019704434, Blast_Score=253, Evalue=4e-68,
Organism=Saccharomyces cerevisiae, GI6321456, Length=429, Percent_Identity=23.7762237762238, Blast_Score=103, Evalue=6e-23,
Organism=Saccharomyces cerevisiae, GI6324386, Length=472, Percent_Identity=23.5169491525424, Blast_Score=98, Evalue=3e-21,
Organism=Drosophila melanogaster, GI21357415, Length=394, Percent_Identity=38.0710659898477, Blast_Score=278, Evalue=6e-75,
Organism=Drosophila melanogaster, GI28574759, Length=434, Percent_Identity=31.1059907834101, Blast_Score=204, Evalue=8e-53,
Organism=Drosophila melanogaster, GI161085790, Length=430, Percent_Identity=30.9302325581395, Blast_Score=202, Evalue=2e-52,
Organism=Drosophila melanogaster, GI21356575, Length=425, Percent_Identity=30.1176470588235, Blast_Score=169, Evalue=3e-42,
Organism=Drosophila melanogaster, GI281366494, Length=407, Percent_Identity=25.3071253071253, Blast_Score=108, Evalue=8e-24,
Organism=Drosophila melanogaster, GI24667139, Length=407, Percent_Identity=25.3071253071253, Blast_Score=108, Evalue=8e-24,
Organism=Drosophila melanogaster, GI24667143, Length=407, Percent_Identity=25.3071253071253, Blast_Score=108, Evalue=8e-24,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 43852; Mature: 43852

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNAAIVSRGEKYVMRTYGRYPMALVRGEGARVWDADGKEYLDFVSGLAVNSLGHCHPRV
CCCCHHHHCCHHHHHHHCCCCCEEEEECCCCEEECCCCHHHHHHHHHHHHHCCCCCCHHH
VEAIREQAGRLIHCSNLYWIEPQVELARLLVENSALDKVFFCNSGAEANEAAIKLARKYA
HHHHHHHCCCEEEECCEEEECCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHH
KEHRGPESYEIITMRRSFHGRTLATLTATGQEKFHHGFAPLPPGFRYAPFNDLSSLRAAV
HHCCCCCCEEEEEEECCCCCCEEEEEEECCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHC
GPRTCAVMLEPVQGEGGVYAANKDYLQAVRALCDDEGLLLIFDEVQCGLGRTGYLFAYQY
CCCEEEEEEEEECCCCCEEECCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEEEEE
YEVEPDILTLAKALAGGVPIGAMLAKERAASAFAPGDHASTFGGNPLATAAGVAAFKALL
EECCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
QEGLVENARVLGQYFYQQLEGLVREFPQLIEVRGRGLLLGVEIDGPAGEVVAACQERGLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHHCCCE
INSLHGHVLRFLPPLIVTREDIDRAVTILKEALHEVLGQGQK
EEHHHHHHHHHHCHHHEEHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDNAAIVSRGEKYVMRTYGRYPMALVRGEGARVWDADGKEYLDFVSGLAVNSLGHCHPRV
CCCCHHHHCCHHHHHHHCCCCCEEEEECCCCEEECCCCHHHHHHHHHHHHHCCCCCCHHH
VEAIREQAGRLIHCSNLYWIEPQVELARLLVENSALDKVFFCNSGAEANEAAIKLARKYA
HHHHHHHCCCEEEECCEEEECCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHH
KEHRGPESYEIITMRRSFHGRTLATLTATGQEKFHHGFAPLPPGFRYAPFNDLSSLRAAV
HHCCCCCCEEEEEEECCCCCCEEEEEEECCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHC
GPRTCAVMLEPVQGEGGVYAANKDYLQAVRALCDDEGLLLIFDEVQCGLGRTGYLFAYQY
CCCEEEEEEEEECCCCCEEECCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEEEEE
YEVEPDILTLAKALAGGVPIGAMLAKERAASAFAPGDHASTFGGNPLATAAGVAAFKALL
EECCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
QEGLVENARVLGQYFYQQLEGLVREFPQLIEVRGRGLLLGVEIDGPAGEVVAACQERGLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHHCCCE
INSLHGHVLRFLPPLIVTREDIDRAVTILKEALHEVLGQGQK
EEHHHHHHHHHHCHHHEEHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]