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The map label for this gene is paaK [H]

Identifier: 83591099

GI number: 83591099

Start: 2387172

End: 2388464

Strand: Reverse

Name: paaK [H]

Synonym: Moth_2278

Alternate gene names: 83591099

Gene position: 2388464-2387172 (Counterclockwise)

Preceding gene: 83591100

Following gene: 83591098

Centisome position: 90.86

GC content: 63.19

Gene sequence:

>1293_bases
ATGATCTGGGATTCGGAAAATGAATGCCGCCCCCGGGCGGAGATCGAGGCCCTGCAACTGGCGCGCCTCCAGGAGACGGT
GGCCAGGGCCTACGAGAGGGTACCCTTTTATCGCCAGGCCATGGAAACAAAAGGTATCCGGCCTTCGGACATCCGCAGCC
TCGAAGACGTGCGCCTGCTCCCCATGACCACCAAGGAGGACTTCCGCCAGAATTACCCCTATGGCCTCTTTGCTGTGCCG
TTGAAGGATGTTGTCCGCCTCCAGGCTTCCTCCGGCACGACCGGTCGGCCGGTGGTGGTGGGTTATACCCGCCGGGATCT
GGAGACCTGGACGGACCTGGTGGCGCGAATGGTTTCCCTGGCCGGGGTGACGCCTGCGGATGTCGCCCAGGTGGTTTTTG
GTTACGGCCTCTTCACCGGCGGTTTTGGCCTGCACTACGGGCTGGAGCGGGTCGGGGCCACTGTTGTCCCGGCCTCGGCC
GGCAATTCCAAGCGCCATATTATGTTAATGCGCGACTTCGGCACTACCGTCTTAGTGGGGACACCTTCTTATATCCTGCA
CCTGGCGGAGGTAGCGGAAGAGGAAGGAGTGGATCCTCAGGCCCTCCCCGTTCGCCTGGGTCTCTTCGGCGGCGAGGCCT
CCAGCCGGGAGATGCTCAAAGAGATCGAGCGGCGCTGGGGGATGCGGGCAACTGACAACTACGGCCTTACGGAGGTGATG
GGTCCCGGCGTTTCCGGCGAGTGCGAGTACCAGGACGGCCAGCACGTGGCCGAGGATCACTTCCTGGTGGAGATCCTGGA
TCCGACCACCGGGGAACCCTGCCCACCCGGGGTCAAGGGCGAGGTGGTCATCACCACCCTGACCAAAGAAGCGTTGCCGG
TGCTACGCTACCGCACCCGGGATATTTCCTCCTTAAACTTTGAACCCTGCCGCTGCGGCCGCACCACGGCCCGCCTGGCC
AAGATTACCGGCCGCACGGACGACATGCTCATTATCCGGGGCGTCAACGTCTTCCCCTCCCAGGTGGAGAGCGTCCTGAT
GGAAATAGACGGCGTGTCGCCCCACTACCAGCTCATCGTCAGCCGGCGCAACTACCTCGACGAGCTGGAGGTGCGGGTGG
AGGTAGATCCTGACTTTTTCAGCGACCGTTACCGTCACCTGGAAGAACTGGAGGAAAAGGTCATGGACCGCCTGCACACG
GTACTGCAGCTGAAGGCCAGGGTGCGCTTGGTGGAACCCCACAGTATCGCCCGGAGCGAGGGCAAGGCCCGGCGGGTGGT
GGATCTGCGGTAG

Upstream 100 bases:

>100_bases
ATGGTGAGCCTCGTCACGCCGGCCTTTTCCAGGGAACATCTAGCTAAAGTTTTTGGTGCTGATAGGACAACTACTACGGC
AACTAAAGGATTGGTGACTG

Downstream 100 bases:

>100_bases
CTGCCACATACCATTAGGGGTCGACTCCGTGCCGACCAACAGATTACAATTGATGAACCTATGTTAGGAGAGGCAGACGG
GGTTACGCTGGCTACAAAAC

Product: phenylacetate-CoA ligase

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MIWDSENECRPRAEIEALQLARLQETVARAYERVPFYRQAMETKGIRPSDIRSLEDVRLLPMTTKEDFRQNYPYGLFAVP
LKDVVRLQASSGTTGRPVVVGYTRRDLETWTDLVARMVSLAGVTPADVAQVVFGYGLFTGGFGLHYGLERVGATVVPASA
GNSKRHIMLMRDFGTTVLVGTPSYILHLAEVAEEEGVDPQALPVRLGLFGGEASSREMLKEIERRWGMRATDNYGLTEVM
GPGVSGECEYQDGQHVAEDHFLVEILDPTTGEPCPPGVKGEVVITTLTKEALPVLRYRTRDISSLNFEPCRCGRTTARLA
KITGRTDDMLIIRGVNVFPSQVESVLMEIDGVSPHYQLIVSRRNYLDELEVRVEVDPDFFSDRYRHLEELEEKVMDRLHT
VLQLKARVRLVEPHSIARSEGKARRVVDLR

Sequences:

>Translated_430_residues
MIWDSENECRPRAEIEALQLARLQETVARAYERVPFYRQAMETKGIRPSDIRSLEDVRLLPMTTKEDFRQNYPYGLFAVP
LKDVVRLQASSGTTGRPVVVGYTRRDLETWTDLVARMVSLAGVTPADVAQVVFGYGLFTGGFGLHYGLERVGATVVPASA
GNSKRHIMLMRDFGTTVLVGTPSYILHLAEVAEEEGVDPQALPVRLGLFGGEASSREMLKEIERRWGMRATDNYGLTEVM
GPGVSGECEYQDGQHVAEDHFLVEILDPTTGEPCPPGVKGEVVITTLTKEALPVLRYRTRDISSLNFEPCRCGRTTARLA
KITGRTDDMLIIRGVNVFPSQVESVLMEIDGVSPHYQLIVSRRNYLDELEVRVEVDPDFFSDRYRHLEELEEKVMDRLHT
VLQLKARVRLVEPHSIARSEGKARRVVDLR
>Mature_430_residues
MIWDSENECRPRAEIEALQLARLQETVARAYERVPFYRQAMETKGIRPSDIRSLEDVRLLPMTTKEDFRQNYPYGLFAVP
LKDVVRLQASSGTTGRPVVVGYTRRDLETWTDLVARMVSLAGVTPADVAQVVFGYGLFTGGFGLHYGLERVGATVVPASA
GNSKRHIMLMRDFGTTVLVGTPSYILHLAEVAEEEGVDPQALPVRLGLFGGEASSREMLKEIERRWGMRATDNYGLTEVM
GPGVSGECEYQDGQHVAEDHFLVEILDPTTGEPCPPGVKGEVVITTLTKEALPVLRYRTRDISSLNFEPCRCGRTTARLA
KITGRTDDMLIIRGVNVFPSQVESVLMEIDGVSPHYQLIVSRRNYLDELEVRVEVDPDFFSDRYRHLEELEEKVMDRLHT
VLQLKARVRLVEPHSIARSEGKARRVVDLR

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=419, Percent_Identity=49.4033412887828, Blast_Score=406, Evalue=1e-114,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 48348; Mature: 48348

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIWDSENECRPRAEIEALQLARLQETVARAYERVPFYRQAMETKGIRPSDIRSLEDVRLL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCHHHHCCHHCCEEE
PMTTKEDFRQNYPYGLFAVPLKDVVRLQASSGTTGRPVVVGYTRRDLETWTDLVARMVSL
CCCCHHHHHHCCCCCEEEECHHHHHEECCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHH
AGVTPADVAQVVFGYGLFTGGFGLHYGLERVGATVVPASAGNSKRHIMLMRDFGTTVLVG
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEECCCCCCCEEEEEEECCCCEEEEE
TPSYILHLAEVAEEEGVDPQALPVRLGLFGGEASSREMLKEIERRWGMRATDNYGLTEVM
CHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCHHHC
GPGVSGECEYQDGQHVAEDHFLVEILDPTTGEPCPPGVKGEVVITTLTKEALPVLRYRTR
CCCCCCEECCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHCC
DISSLNFEPCRCGRTTARLAKITGRTDDMLIIRGVNVFPSQVESVLMEIDGVSPHYQLIV
CCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHH
SRRNYLDELEVRVEVDPDFFSDRYRHLEELEEKVMDRLHTVLQLKARVRLVEPHSIARSE
HHHHHHCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHCC
GKARRVVDLR
CCCCCCCCCC
>Mature Secondary Structure
MIWDSENECRPRAEIEALQLARLQETVARAYERVPFYRQAMETKGIRPSDIRSLEDVRLL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCHHHHCCHHCCEEE
PMTTKEDFRQNYPYGLFAVPLKDVVRLQASSGTTGRPVVVGYTRRDLETWTDLVARMVSL
CCCCHHHHHHCCCCCEEEECHHHHHEECCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHH
AGVTPADVAQVVFGYGLFTGGFGLHYGLERVGATVVPASAGNSKRHIMLMRDFGTTVLVG
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEECCCCCCCEEEEEEECCCCEEEEE
TPSYILHLAEVAEEEGVDPQALPVRLGLFGGEASSREMLKEIERRWGMRATDNYGLTEVM
CHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCHHHC
GPGVSGECEYQDGQHVAEDHFLVEILDPTTGEPCPPGVKGEVVITTLTKEALPVLRYRTR
CCCCCCEECCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHCC
DISSLNFEPCRCGRTTARLAKITGRTDDMLIIRGVNVFPSQVESVLMEIDGVSPHYQLIV
CCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHH
SRRNYLDELEVRVEVDPDFFSDRYRHLEELEEKVMDRLHTVLQLKARVRLVEPHSIARSE
HHHHHHCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHCC
GKARRVVDLR
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]