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The map label for this gene is hyfD [H]

Identifier: 83591010

GI number: 83591010

Start: 2285354

End: 2286796

Strand: Reverse

Name: hyfD [H]

Synonym: Moth_2187

Alternate gene names: 83591010

Gene position: 2286796-2285354 (Counterclockwise)

Preceding gene: 83591011

Following gene: 83591009

Centisome position: 86.99

GC content: 50.8

Gene sequence:

>1443_bases
ATGGTAGAATATGCCGTAGCAAGCATTTTAATCCCCATACTGGGAAGCGTCTTGGCTGTAATCATGCCAGGCAGCTATGT
AAAGAGAATAAGCCCGCTGTTTGCTTTCCTGACTTTTGCCAGTAGCCTGCTTCTAATGATTGATTTTACCCGGGCGGGAG
GAGCCAGCATCACCCAGGGGTTGTTACAGTTTGGCGGCATGCAGGTACTCGGCGTTACAATCGACAAGGTCAGTGTCCTG
ATCGGTTTTGCCGTAATCTTTATGGGCCTGCTGGTCTGTGTTTATTCCCTGGGGTATATGACCACCAGCAATAAGGAACA
CCCTGTTCACGGTGGCACCAAGAGATATTACGCTTTTTTGCTGCTCTTTATCGGTTCCATGGCGGGGCTGGTATTTTCTT
CCACAATAATCGGGCTGCTGGTGTTTTTTGAGCTAACCGGTGTTTGCTCATGGGGTCTGATAGGATTTTATGACACACCA
GCAGCACGCCGGGCGGCCCTCAAGGCCCTTATAATAACCCACGTGGCTTCTATTGGTCTGTATGTGGCGGCCATCTATTT
ATTCATTAACAGTGGCAGTTTTGAGCTGGCGGCCCTCGCTGGATTGAAGGATACAGCCAAGGTTGTAGTATTCCTGGGTA
TACTTGTTGCCTCCTGGGGCAAGTCGGCCCAGTTACCTCTTCATTCATGGCTTCCTGACGCTATGGTTGCACCTACACCT
GTCAGCGCCTATTTACATGCAGCATCAATGGTGAAGGTCGGGGCCTATATTTTTGCCCGGACCCTGTTATCAGCAGGAAG
TGTACCCCAGGTCATCGGCTACATCGGTGGGATTATGGCAATAGTTACCCTGGCGTACGGCTTTGCAATGTATTTCCCCC
AGCAGGATATGAAAAAACTGCTGGCCTATTCTACGATAGCTCAGCTTTCATATATATTTCTTGCCCTGTCCATTTCGGTT
TTCGGTTCGTCCATGGCCTACAAAGGGGCAGTGGCCCACATTTTCAACCATGCCTTTGCCAAGGGACTGTTCTTCCTCGT
GGCAGGGGCCCTCAGCTATACAACCGGTACCCGGATGCTACCTCAGCTGCGCGGGATATTGAGCAAAATGCCGCTGGTGG
GTGTTAGTTTTGCTGCCGCTGCTCTTGCTGTTGGAGGAACGCCGCCTTTTAACCTCTTCTTTAGCAAGTTTAGCATTTTC
GTAGGCGGCTTTGAGGCGGCGAAAAACCATCCCATCGTGCTCCTGCTCGTCCTGGTGGCGGTTGTTGAGTCAGTCGGGAG
TTTTGCCTGGCTTTTGCGGTGGTTCGGTACCTGTGTAATGGGTAAACCTTCAGAGACAGTTGCCGGCGCGATTACTCTCC
CCCTGTCAATGAAAATAGTACTCCTGTTGCTCGTGGTTATGACGCTAATCTCTCAGTATATCGCCCTGGTATTCCTGGGA
TAG

Upstream 100 bases:

>100_bases
TGTTCCTGCTGATGGCCGGATTGGGGATATATATACCTGCACCGTTGAATCAATTGCTGCAGAGTGCAGTTAACGTTGTC
CTGGGAGCGAGGTAATAAAT

Downstream 100 bases:

>100_bases
GGGAACATTTATCATGACCAAAACGGCTGAGATGCCCTTGAAGATTGATTTGGCAGTTTTTTGGGGGAAATTATATCGGG
AGGTAGATGAAGATGGGACA

Product: hydrogenase 4 subunit D

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 480; Mature: 480

Protein sequence:

>480_residues
MVEYAVASILIPILGSVLAVIMPGSYVKRISPLFAFLTFASSLLLMIDFTRAGGASITQGLLQFGGMQVLGVTIDKVSVL
IGFAVIFMGLLVCVYSLGYMTTSNKEHPVHGGTKRYYAFLLLFIGSMAGLVFSSTIIGLLVFFELTGVCSWGLIGFYDTP
AARRAALKALIITHVASIGLYVAAIYLFINSGSFELAALAGLKDTAKVVVFLGILVASWGKSAQLPLHSWLPDAMVAPTP
VSAYLHAASMVKVGAYIFARTLLSAGSVPQVIGYIGGIMAIVTLAYGFAMYFPQQDMKKLLAYSTIAQLSYIFLALSISV
FGSSMAYKGAVAHIFNHAFAKGLFFLVAGALSYTTGTRMLPQLRGILSKMPLVGVSFAAAALAVGGTPPFNLFFSKFSIF
VGGFEAAKNHPIVLLLVLVAVVESVGSFAWLLRWFGTCVMGKPSETVAGAITLPLSMKIVLLLLVVMTLISQYIALVFLG

Sequences:

>Translated_480_residues
MVEYAVASILIPILGSVLAVIMPGSYVKRISPLFAFLTFASSLLLMIDFTRAGGASITQGLLQFGGMQVLGVTIDKVSVL
IGFAVIFMGLLVCVYSLGYMTTSNKEHPVHGGTKRYYAFLLLFIGSMAGLVFSSTIIGLLVFFELTGVCSWGLIGFYDTP
AARRAALKALIITHVASIGLYVAAIYLFINSGSFELAALAGLKDTAKVVVFLGILVASWGKSAQLPLHSWLPDAMVAPTP
VSAYLHAASMVKVGAYIFARTLLSAGSVPQVIGYIGGIMAIVTLAYGFAMYFPQQDMKKLLAYSTIAQLSYIFLALSISV
FGSSMAYKGAVAHIFNHAFAKGLFFLVAGALSYTTGTRMLPQLRGILSKMPLVGVSFAAAALAVGGTPPFNLFFSKFSIF
VGGFEAAKNHPIVLLLVLVAVVESVGSFAWLLRWFGTCVMGKPSETVAGAITLPLSMKIVLLLLVVMTLISQYIALVFLG
>Mature_480_residues
MVEYAVASILIPILGSVLAVIMPGSYVKRISPLFAFLTFASSLLLMIDFTRAGGASITQGLLQFGGMQVLGVTIDKVSVL
IGFAVIFMGLLVCVYSLGYMTTSNKEHPVHGGTKRYYAFLLLFIGSMAGLVFSSTIIGLLVFFELTGVCSWGLIGFYDTP
AARRAALKALIITHVASIGLYVAAIYLFINSGSFELAALAGLKDTAKVVVFLGILVASWGKSAQLPLHSWLPDAMVAPTP
VSAYLHAASMVKVGAYIFARTLLSAGSVPQVIGYIGGIMAIVTLAYGFAMYFPQQDMKKLLAYSTIAQLSYIFLALSISV
FGSSMAYKGAVAHIFNHAFAKGLFFLVAGALSYTTGTRMLPQLRGILSKMPLVGVSFAAAALAVGGTPPFNLFFSKFSIF
VGGFEAAKNHPIVLLLVLVAVVESVGSFAWLLRWFGTCVMGKPSETVAGAITLPLSMKIVLLLLVVMTLISQYIALVFLG

Specific function: Unknown

COG id: COG1009

COG function: function code CP; NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 5 family [H]

Homologues:

Organism=Homo sapiens, GI251831117, Length=332, Percent_Identity=30.1204819277108, Blast_Score=125, Evalue=6e-29,
Organism=Escherichia coli, GI1788829, Length=479, Percent_Identity=55.3235908141962, Blast_Score=530, Evalue=1e-151,
Organism=Escherichia coli, GI1788614, Length=413, Percent_Identity=31.9612590799031, Blast_Score=165, Evalue=6e-42,
Organism=Escherichia coli, GI1788831, Length=411, Percent_Identity=30.4136253041363, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1788827, Length=425, Percent_Identity=27.0588235294118, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1788613, Length=424, Percent_Identity=25.9433962264151, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI2367154, Length=261, Percent_Identity=24.904214559387, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI145693160, Length=344, Percent_Identity=23.8372093023256, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001750
- InterPro:   IPR001516 [H]

Pfam domain/function: PF00361 Oxidored_q1; PF00662 Oxidored_q1_N [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 50989; Mature: 50989

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEYAVASILIPILGSVLAVIMPGSYVKRISPLFAFLTFASSLLLMIDFTRAGGASITQG
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
LLQFGGMQVLGVTIDKVSVLIGFAVIFMGLLVCVYSLGYMTTSNKEHPVHGGTKRYYAFL
HHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
LLFIGSMAGLVFSSTIIGLLVFFELTGVCSWGLIGFYDTPAARRAALKALIITHVASIGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
YVAAIYLFINSGSFELAALAGLKDTAKVVVFLGILVASWGKSAQLPLHSWLPDAMVAPTP
HHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCC
VSAYLHAASMVKVGAYIFARTLLSAGSVPQVIGYIGGIMAIVTLAYGFAMYFPQQDMKKL
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
LAYSTIAQLSYIFLALSISVFGSSMAYKGAVAHIFNHAFAKGLFFLVAGALSYTTGTRML
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PQLRGILSKMPLVGVSFAAAALAVGGTPPFNLFFSKFSIFVGGFEAAKNHPIVLLLVLVA
HHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHH
VVESVGSFAWLLRWFGTCVMGKPSETVAGAITLPLSMKIVLLLLVVMTLISQYIALVFLG
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVEYAVASILIPILGSVLAVIMPGSYVKRISPLFAFLTFASSLLLMIDFTRAGGASITQG
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
LLQFGGMQVLGVTIDKVSVLIGFAVIFMGLLVCVYSLGYMTTSNKEHPVHGGTKRYYAFL
HHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
LLFIGSMAGLVFSSTIIGLLVFFELTGVCSWGLIGFYDTPAARRAALKALIITHVASIGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
YVAAIYLFINSGSFELAALAGLKDTAKVVVFLGILVASWGKSAQLPLHSWLPDAMVAPTP
HHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCC
VSAYLHAASMVKVGAYIFARTLLSAGSVPQVIGYIGGIMAIVTLAYGFAMYFPQQDMKKL
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
LAYSTIAQLSYIFLALSISVFGSSMAYKGAVAHIFNHAFAKGLFFLVAGALSYTTGTRML
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PQLRGILSKMPLVGVSFAAAALAVGGTPPFNLFFSKFSIFVGGFEAAKNHPIVLLLVLVA
HHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHH
VVESVGSFAWLLRWFGTCVMGKPSETVAGAITLPLSMKIVLLLLVVMTLISQYIALVFLG
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]