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The map label for this gene is mttC2 [H]

Identifier: 83590940

GI number: 83590940

Start: 2209107

End: 2210930

Strand: Reverse

Name: mttC2 [H]

Synonym: Moth_2114

Alternate gene names: 83590940

Gene position: 2210930-2209107 (Counterclockwise)

Preceding gene: 83590941

Following gene: 83590939

Centisome position: 84.1

GC content: 58.17

Gene sequence:

>1824_bases
ATGGCATCCTTTTCCCTGGAAAATCTAATCCAGGCTGTAATCGACGGCAACGCTGTCAAGGTCCGGGAAGAAGTAAAAAG
GGCCTTGGCAGCGGGGATCGAACCGGCCCGGATCATAACCGATGGCTTTGTGGCAGCCATGGATGTAGTGGGGGAAAGGT
TCGAACGCAACGAGATTTACGTAACTGACTTGATTATTACCGCCCGGGCCATGCATACCGGCCTCAAGGAACTTAAGCCC
CTGATGCTGGCCGGTAAGGTGCAACCGGTGGGGCGGGCCATTGTCGGTACTGTCCAGGGGGACATCCATGATATCGGCAA
GAATCTCCTCGCCATCATGCTCGAGGCATCGGGCTTTGAGGTTATCGACCTGGGCGTGAACGTAGCCCCCAGCACCTTTG
TGGAGGCGGTCATTAAGCACCGTCCCGATGTCCTCTGCCTCTCGGCCCTCCTTTCTTCTACCCGCAAGGGTATGGAGGAA
ACTATTACTGCCCTGCGGGAGGCCGGCTGGCGGGATAAAGTAAAGGTTGTCGTAGGCGGCACCCCCCTGAATGAAAAGAT
TGCCGCCAGGATGGGAGCTGACGGCTACGCCCCCGATGCCACGGCGGCTATACCTCTGATTAAGAGCCTGATCGGTGCCG
ACCGCAAGCGCCGGGCCGTCCTGGCTCCGGCTACCCTGGACCTGTTTTTCGGGGAGGGTTCCCTGGAAGACCTGCAGCGT
GCCTTTACCCGGATGACAGGCCTGCATCTGGTCATGGTGGATGCCGCCGGCCGCCCATTGACTTCCCTGGGCGGTTTCCT
GGAGTGTTCCCGCCATTGCCACCTGCTTAAGGAAAACCCGGCCAGAGCCCAAGATGTCACCACCCTCCAGGGCAATTTTA
AAGAAGCTTTTATTTATCGCTGTCATGCCGGGTTGGTGGAAATTTCCTACCCTCTGGCCAATGAGGATGGGACGGTGGGG
GCCGTCCTCTGTGGCCACTGCCTCTTGAGAGGCGACCCTGACCCGGCCGATTTGAAGGCAGCCGTCCCAGTCTTATCCCT
AACGGACCTGGAAGCTGTTTGCGGTCTTCTCTCCTTTGTATCCGGCCAGATCATGCAGCTCAACACCGTTTTACTGGTCA
ATAAGGAACTGGAGGACCAGCAGGCGAGCTTCATCCACTTCCTTAAGCGGCAGCACCAGCTGGAACAGGCCCTGAAGGAC
GCCGAACTCAAGGCCCTCCAATCCCAGGTCAACCCCCACTTCCTCTTTAATTCTTTAAATACCGTAGCCCGCCTGGCCCT
CCTGGAAGGGGCGGCCAATACGGAAAAAATGGTCCGCGCCCTGGCCCGCCTCATGCGCTACAGCCTCTACCAGGTCAAGG
GAACGGTTTCCCTGGCAGAAGAAATAGCTGCCGTGCGCGACTACCTTTTTATCCAGGAAACGCGGTTTTCAGACCGGGTC
CGGAGCCGGGTGAAAGTAGAAGAGGCCGCCATGCAGGCCCGGCTGCCCTGCATGGTCCTGCAACCCCTGGTGGAGAATGC
TATTATCCATGGCCTGGAACCCAAGGAGGAGGGAGGGGAAATCACCGTATCCGCCCGCCTGGTGGGCGACCAGGTCCGGG
TAGAAATCAAGGATGACGGGGTCGGAATACCGCCGGAGGTGAAAAAGGCGATCTTTGACCTGGAAGTCCGGCGGAGCGGT
AAAGGCCAGGTAAGCGGCCTGGGGATAGTCAATGTCTACCGGCGCCTGCAGCACCATTTTGGTAGCAACTGCGCCCTGGA
TGTAGCCAGTATGCCGGGAAAAGGTACTTGCGTCCAGCTGACTTTTCCTTATACTGTGGATTAG

Upstream 100 bases:

>100_bases
TGCCGCCCGGGCCGGGAAGATTAAGGCCTGATCTGGCAAGCAACTTGCGGCCGCAGGAGGGAGGTTTCCCTACTGCGGTT
GTTTTATTAGGAGGAGTAAT

Downstream 100 bases:

>100_bases
GCGTGGGAAAGAGTAAGTTTCCGAGGGGGGCAGCAACCAGCCTTGGCCACGGATATCAAGATCCTGCTTGTCGACGACGA
ACCCCTGGAGCGCCAGGCCA

Product: histidine kinase

Products: NA

Alternate protein names: TCP 2 [H]

Number of amino acids: Translated: 607; Mature: 606

Protein sequence:

>607_residues
MASFSLENLIQAVIDGNAVKVREEVKRALAAGIEPARIITDGFVAAMDVVGERFERNEIYVTDLIITARAMHTGLKELKP
LMLAGKVQPVGRAIVGTVQGDIHDIGKNLLAIMLEASGFEVIDLGVNVAPSTFVEAVIKHRPDVLCLSALLSSTRKGMEE
TITALREAGWRDKVKVVVGGTPLNEKIAARMGADGYAPDATAAIPLIKSLIGADRKRRAVLAPATLDLFFGEGSLEDLQR
AFTRMTGLHLVMVDAAGRPLTSLGGFLECSRHCHLLKENPARAQDVTTLQGNFKEAFIYRCHAGLVEISYPLANEDGTVG
AVLCGHCLLRGDPDPADLKAAVPVLSLTDLEAVCGLLSFVSGQIMQLNTVLLVNKELEDQQASFIHFLKRQHQLEQALKD
AELKALQSQVNPHFLFNSLNTVARLALLEGAANTEKMVRALARLMRYSLYQVKGTVSLAEEIAAVRDYLFIQETRFSDRV
RSRVKVEEAAMQARLPCMVLQPLVENAIIHGLEPKEEGGEITVSARLVGDQVRVEIKDDGVGIPPEVKKAIFDLEVRRSG
KGQVSGLGIVNVYRRLQHHFGSNCALDVASMPGKGTCVQLTFPYTVD

Sequences:

>Translated_607_residues
MASFSLENLIQAVIDGNAVKVREEVKRALAAGIEPARIITDGFVAAMDVVGERFERNEIYVTDLIITARAMHTGLKELKP
LMLAGKVQPVGRAIVGTVQGDIHDIGKNLLAIMLEASGFEVIDLGVNVAPSTFVEAVIKHRPDVLCLSALLSSTRKGMEE
TITALREAGWRDKVKVVVGGTPLNEKIAARMGADGYAPDATAAIPLIKSLIGADRKRRAVLAPATLDLFFGEGSLEDLQR
AFTRMTGLHLVMVDAAGRPLTSLGGFLECSRHCHLLKENPARAQDVTTLQGNFKEAFIYRCHAGLVEISYPLANEDGTVG
AVLCGHCLLRGDPDPADLKAAVPVLSLTDLEAVCGLLSFVSGQIMQLNTVLLVNKELEDQQASFIHFLKRQHQLEQALKD
AELKALQSQVNPHFLFNSLNTVARLALLEGAANTEKMVRALARLMRYSLYQVKGTVSLAEEIAAVRDYLFIQETRFSDRV
RSRVKVEEAAMQARLPCMVLQPLVENAIIHGLEPKEEGGEITVSARLVGDQVRVEIKDDGVGIPPEVKKAIFDLEVRRSG
KGQVSGLGIVNVYRRLQHHFGSNCALDVASMPGKGTCVQLTFPYTVD
>Mature_606_residues
ASFSLENLIQAVIDGNAVKVREEVKRALAAGIEPARIITDGFVAAMDVVGERFERNEIYVTDLIITARAMHTGLKELKPL
MLAGKVQPVGRAIVGTVQGDIHDIGKNLLAIMLEASGFEVIDLGVNVAPSTFVEAVIKHRPDVLCLSALLSSTRKGMEET
ITALREAGWRDKVKVVVGGTPLNEKIAARMGADGYAPDATAAIPLIKSLIGADRKRRAVLAPATLDLFFGEGSLEDLQRA
FTRMTGLHLVMVDAAGRPLTSLGGFLECSRHCHLLKENPARAQDVTTLQGNFKEAFIYRCHAGLVEISYPLANEDGTVGA
VLCGHCLLRGDPDPADLKAAVPVLSLTDLEAVCGLLSFVSGQIMQLNTVLLVNKELEDQQASFIHFLKRQHQLEQALKDA
ELKALQSQVNPHFLFNSLNTVARLALLEGAANTEKMVRALARLMRYSLYQVKGTVSLAEEIAAVRDYLFIQETRFSDRVR
SRVKVEEAAMQARLPCMVLQPLVENAIIHGLEPKEEGGEITVSARLVGDQVRVEIKDDGVGIPPEVKKAIFDLEVRRSGK
GQVSGLGIVNVYRRLQHHFGSNCALDVASMPGKGTCVQLTFPYTVD

Specific function: Acts probably as a methyl group carrier between mttB and either mtbA or mtaA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 B12-binding N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI169790923, Length=207, Percent_Identity=28.0193236714976, Blast_Score=76, Evalue=8e-14,
Organism=Escherichia coli, GI1788446, Length=235, Percent_Identity=32.7659574468085, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI1788723, Length=197, Percent_Identity=31.4720812182741, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI1790450, Length=179, Percent_Identity=26.2569832402235, Blast_Score=81, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17535405, Length=249, Percent_Identity=24.8995983935743, Blast_Score=79, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006158
- InterPro:   IPR003759
- InterPro:   IPR012741 [H]

Pfam domain/function: PF02310 B12-binding; PF02607 B12-binding_2 [H]

EC number: NA

Molecular weight: Translated: 65988; Mature: 65857

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASFSLENLIQAVIDGNAVKVREEVKRALAAGIEPARIITDGFVAAMDVVGERFERNEIY
CCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEE
VTDLIITARAMHTGLKELKPLMLAGKVQPVGRAIVGTVQGDIHDIGKNLLAIMLEASGFE
EEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCHHHHHHHHHHHHHHEECCCCE
VIDLGVNVAPSTFVEAVIKHRPDVLCLSALLSSTRKGMEETITALREAGWRDKVKVVVGG
EEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEECC
TPLNEKIAARMGADGYAPDATAAIPLIKSLIGADRKRRAVLAPATLDLFFGEGSLEDLQR
CCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCEEECCEEEEEEECCCCHHHHHH
AFTRMTGLHLVMVDAAGRPLTSLGGFLECSRHCHLLKENPARAQDVTTLQGNFKEAFIYR
HHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHCHHHCCCHHHHHHHH
CHAGLVEISYPLANEDGTVGAVLCGHCLLRGDPDPADLKAAVPVLSLTDLEAVCGLLSFV
HCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHCCHHHHCCHHHHHHHHHHH
SGQIMQLNTVLLVNKELEDQQASFIHFLKRQHQLEQALKDAELKALQSQVNPHFLFNSLN
CCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
TVARLALLEGAANTEKMVRALARLMRYSLYQVKGTVSLAEEIAAVRDYLFIQETRFSDRV
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSRVKVEEAAMQARLPCMVLQPLVENAIIHGLEPKEEGGEITVSARLVGDQVRVEIKDDG
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCEEEEEECCCC
VGIPPEVKKAIFDLEVRRSGKGQVSGLGIVNVYRRLQHHFGSNCALDVASMPGKGTCVQL
CCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEE
TFPYTVD
ECCCCCC
>Mature Secondary Structure 
ASFSLENLIQAVIDGNAVKVREEVKRALAAGIEPARIITDGFVAAMDVVGERFERNEIY
CCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEE
VTDLIITARAMHTGLKELKPLMLAGKVQPVGRAIVGTVQGDIHDIGKNLLAIMLEASGFE
EEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCHHHHHHHHHHHHHHEECCCCE
VIDLGVNVAPSTFVEAVIKHRPDVLCLSALLSSTRKGMEETITALREAGWRDKVKVVVGG
EEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEECC
TPLNEKIAARMGADGYAPDATAAIPLIKSLIGADRKRRAVLAPATLDLFFGEGSLEDLQR
CCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCEEECCEEEEEEECCCCHHHHHH
AFTRMTGLHLVMVDAAGRPLTSLGGFLECSRHCHLLKENPARAQDVTTLQGNFKEAFIYR
HHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHCHHHCCCHHHHHHHH
CHAGLVEISYPLANEDGTVGAVLCGHCLLRGDPDPADLKAAVPVLSLTDLEAVCGLLSFV
HCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHCCHHHHCCHHHHHHHHHHH
SGQIMQLNTVLLVNKELEDQQASFIHFLKRQHQLEQALKDAELKALQSQVNPHFLFNSLN
CCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
TVARLALLEGAANTEKMVRALARLMRYSLYQVKGTVSLAEEIAAVRDYLFIQETRFSDRV
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSRVKVEEAAMQARLPCMVLQPLVENAIIHGLEPKEEGGEITVSARLVGDQVRVEIKDDG
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCEEEEEECCCC
VGIPPEVKKAIFDLEVRRSGKGQVSGLGIVNVYRRLQHHFGSNCALDVASMPGKGTCVQL
CCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEE
TFPYTVD
ECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]