Click here to switch to the map view.

The map label for this gene is glpT [H]

Identifier: 83590929

GI number: 83590929

Start: 2195833

End: 2197182

Strand: Reverse

Name: glpT [H]

Synonym: Moth_2103

Alternate gene names: 83590929

Gene position: 2197182-2195833 (Counterclockwise)

Preceding gene: 83590931

Following gene: 83590928

Centisome position: 83.58

GC content: 47.41

Gene sequence:

>1350_bases
ATGAGTAAATCCTTGTCACCCTCAACAGGATGGTGGCGTTATCGTTACCTGGTGGCAGCTATTGTTTTCTTCGGGTATAG
CATTCAGTACCTAGACCGGGTAAAAACGACAGTGTTAGTTCCGCTAATTAGTCAGAGCTTGCACCTGACCCATAGCGATG
TTGGTAACGCCATGTTTTTATTAATGATTTTTTATGGCCCAACCCAGATATTATCGGGATTTCTTTGCGATCGCTTTGGT
CCCAAAAAAGTTTTGGTATTCTCCCTGATCACCTGGAGCATATTCACGATATATATGGCGTATATGCAGAACGCAACTGA
GTGGTATATCCGTAATGCCTTGTTTGGTATTTTTGTAGGTACTGAATTTGTACCCAGTGCACGCTTGATCGCGCGCTGGT
TTCCTAAAAGAGAACGGGCCCAGGCCCAGGGGGTCCTCTCCTGGTCCTGGATTATTACCCCTGCGTGGGCTCCTTTGCTA
ACAACGTTTCTAGCCTCCTATTTTAACGATTGGCGTCCTGTTTTTATATGGCTAGGTATTTTTGGCCTGGTACCCCTGGT
AATAGTACTTCTCTTCATTTACGATCGTCCCGAACAGGTACGCTGGCTGAGCGACAGGGAAGTTAAAGAGAGTTACGCCG
ACGAACTTGAGAGTGGCATCTTAAAAGAGGCGGCAATAAGCCGTGAGAACCTGGCCAAGCAGGCCAAAAAAGCCGAAATA
CCCTTGCGCGATGTCTTGTTAAACAAGAGCTTCATAGCAGTAGTGCTATCTTACCTGGCCTGCCAGATGACCTTCTGGGG
GATAGTAACCTGGTCGCCAAGCTATTTAAGTGAAGTGTTTAAATTTAACCTGATGAAAATGGGCGTCTGGGCTTCGATTT
ATTTTGCAGCCGGTGTCATCGGCGCCTTCTTGAGCTCCCGGATTTCCGATAAATTCTTTAATGGCCGCCGCCGGCCCATG
ATAATTCTTTCGTTCCTCGGCACTATCCCCTTTATCCTACTTTTGGCTATGTCCCGGCCGGGAATCAGCCATATGGGGCT
GATGCTAATCCTAGCCGGAGCCGGATTTTTTGCCAATATGATCTGGGGTCCTATTTTAGCCTGGCCGGCTGACGTTTTTA
GCCCGGAGATGTATGGGCGGGCCCTCGGCTTTGTGACGGGTATAGCCTATTTTGGGGCCGCTTTTGCTCCTCTTATTATG
AGCCGCCTAATCATTAAAACACCTGCAGGTGTTTCTTATACCTATGCCTGGACTTTTATTGCTTTTTGCGCAGTTGCAGG
TTTAATTGCTTCTGCCATTGTCAGAGACCGGCAGGATATAAGTAACAACAGTATTTCCCTGTCGGAATAA

Upstream 100 bases:

>100_bases
TTATATTTAGTCCATACTCAGAAAACTGGTGCAGGGAGGAGGGAAGAAAGGGCACCGCTGAGGTGGACGCAAGTATTTAA
ATTTAAGGAAGGGGAGGTCT

Downstream 100 bases:

>100_bases
ACCTTTCGAGGTGAGAACTTTGCCTGCCATGACCCCCAAAGAGCGTTTCTTGCGTGCCTTAAACCGCGAACATGTAGACC
GCATCCCGGTAGGTAACCCG

Product: major facilitator transporter

Products: Proton [Cytoplasm]; glycerol-3-phosphate [Cytoplasm] [C]

Alternate protein names: G-3-P transporter; G-3-P permease [H]

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MSKSLSPSTGWWRYRYLVAAIVFFGYSIQYLDRVKTTVLVPLISQSLHLTHSDVGNAMFLLMIFYGPTQILSGFLCDRFG
PKKVLVFSLITWSIFTIYMAYMQNATEWYIRNALFGIFVGTEFVPSARLIARWFPKRERAQAQGVLSWSWIITPAWAPLL
TTFLASYFNDWRPVFIWLGIFGLVPLVIVLLFIYDRPEQVRWLSDREVKESYADELESGILKEAAISRENLAKQAKKAEI
PLRDVLLNKSFIAVVLSYLACQMTFWGIVTWSPSYLSEVFKFNLMKMGVWASIYFAAGVIGAFLSSRISDKFFNGRRRPM
IILSFLGTIPFILLLAMSRPGISHMGLMLILAGAGFFANMIWGPILAWPADVFSPEMYGRALGFVTGIAYFGAAFAPLIM
SRLIIKTPAGVSYTYAWTFIAFCAVAGLIASAIVRDRQDISNNSISLSE

Sequences:

>Translated_449_residues
MSKSLSPSTGWWRYRYLVAAIVFFGYSIQYLDRVKTTVLVPLISQSLHLTHSDVGNAMFLLMIFYGPTQILSGFLCDRFG
PKKVLVFSLITWSIFTIYMAYMQNATEWYIRNALFGIFVGTEFVPSARLIARWFPKRERAQAQGVLSWSWIITPAWAPLL
TTFLASYFNDWRPVFIWLGIFGLVPLVIVLLFIYDRPEQVRWLSDREVKESYADELESGILKEAAISRENLAKQAKKAEI
PLRDVLLNKSFIAVVLSYLACQMTFWGIVTWSPSYLSEVFKFNLMKMGVWASIYFAAGVIGAFLSSRISDKFFNGRRRPM
IILSFLGTIPFILLLAMSRPGISHMGLMLILAGAGFFANMIWGPILAWPADVFSPEMYGRALGFVTGIAYFGAAFAPLIM
SRLIIKTPAGVSYTYAWTFIAFCAVAGLIASAIVRDRQDISNNSISLSE
>Mature_448_residues
SKSLSPSTGWWRYRYLVAAIVFFGYSIQYLDRVKTTVLVPLISQSLHLTHSDVGNAMFLLMIFYGPTQILSGFLCDRFGP
KKVLVFSLITWSIFTIYMAYMQNATEWYIRNALFGIFVGTEFVPSARLIARWFPKRERAQAQGVLSWSWIITPAWAPLLT
TFLASYFNDWRPVFIWLGIFGLVPLVIVLLFIYDRPEQVRWLSDREVKESYADELESGILKEAAISRENLAKQAKKAEIP
LRDVLLNKSFIAVVLSYLACQMTFWGIVTWSPSYLSEVFKFNLMKMGVWASIYFAAGVIGAFLSSRISDKFFNGRRRPMI
ILSFLGTIPFILLLAMSRPGISHMGLMLILAGAGFFANMIWGPILAWPADVFSPEMYGRALGFVTGIAYFGAAFAPLIMS
RLIIKTPAGVSYTYAWTFIAFCAVAGLIASAIVRDRQDISNNSISLSE

Specific function: Responsible for glycerol-3-phosphate uptake [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=330, Percent_Identity=22.1212121212121, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1788573, Length=392, Percent_Identity=24.7448979591837, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1789515, Length=432, Percent_Identity=24.0740740740741, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI87082320, Length=318, Percent_Identity=24.2138364779874, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87082310, Length=398, Percent_Identity=25.6281407035176, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI2367379, Length=443, Percent_Identity=23.7020316027088, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1789152, Length=310, Percent_Identity=26.1290322580645, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1786229, Length=333, Percent_Identity=22.2222222222222, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI25141318, Length=250, Percent_Identity=26.8, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI86561091, Length=250, Percent_Identity=26.4, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI25141316, Length=250, Percent_Identity=26.4, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI25141341, Length=244, Percent_Identity=26.6393442622951, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI20130135, Length=425, Percent_Identity=21.8823529411765, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24655271, Length=425, Percent_Identity=21.8823529411765, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24648416, Length=319, Percent_Identity=24.1379310344828, Blast_Score=69, Evalue=9e-12,
Organism=Drosophila melanogaster, GI21356189, Length=319, Percent_Identity=24.1379310344828, Blast_Score=69, Evalue=9e-12,
Organism=Drosophila melanogaster, GI19920686, Length=355, Percent_Identity=24.2253521126761, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24583789, Length=361, Percent_Identity=24.0997229916898, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005267
- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR021159 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 50710; Mature: 50579

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SKSLSPSTGWWRYRYLVAAIVFFGYSIQYLDRVKTTVLVPLISQSLHLTHSDVGNAMFL
CCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LMIFYGPTQILSGFLCDRFGPKKVLVFSLITWSIFTIYMAYMQNATEWYIRNALFGIFVG
HHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TEFVPSARLIARWFPKRERAQAQGVLSWSWIITPAWAPLLTTFLASYFNDWRPVFIWLGI
CHHCCHHHHHHHHCCCHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHH
FGLVPLVIVLLFIYDRPEQVRWLSDREVKESYADELESGILKEAAISRENLAKQAKKAEI
HHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PLRDVLLNKSFIAVVLSYLACQMTFWGIVTWSPSYLSEVFKFNLMKMGVWASIYFAAGVI
CHHHHHHCHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAFLSSRISDKFFNGRRRPMIILSFLGTIPFILLLAMSRPGISHMGLMLILAGAGFFANM
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
IWGPILAWPADVFSPEMYGRALGFVTGIAYFGAAFAPLIMSRLIIKTPAGVSYTYAWTFI
HHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
AFCAVAGLIASAIVRDRQDISNNSISLSE
HHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; glycerol-3-phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + glycerol-3-phosphate [Periplasm] = Proton [Cytoplasm] + glycerol-3-phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3329281; 9205837; 9278503; 3141744; 12893936 [H]