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The map label for this gene is 83590798

Identifier: 83590798

GI number: 83590798

Start: 2047566

End: 2049335

Strand: Reverse

Name: 83590798

Synonym: Moth_1966

Alternate gene names: NA

Gene position: 2049335-2047566 (Counterclockwise)

Preceding gene: 83590799

Following gene: 83590797

Centisome position: 77.96

GC content: 60.62

Gene sequence:

>1770_bases
ATGGAAGAGAAGAAACGCGCCGGCGCCCTGCGGGATGTTGATCCCTTTACCGTGGAAATTATCAAGGATTCCCTGATAGC
CATTGGCGATGAGATGTTCGTGGCCCTCCAGCGCACCAGCAAGAGCACCATTATCTACGAGGTCCTCGACTATGCCTGCG
GCCTCACCGACAACCAGGCCCGGTTAATTACCCAGGGCAACGGGGTGACCGGTTTTCTGGGTACCCTGGATTTTTCCGTC
AAGGACGCCATCAATAAATTTGCTGCCCGGGGCCTCTTGAACCCCGGGGATGTCATTATCACCAACGATCCTTACGGCGG
CGGCGGTACCCACCTCTCCGACGTCTGCCTGGTCATGCCCATCTTCTATGATGGCGAGATCGTTGCCTATTCGGCCAACA
AGGCCCACTGGACCGAAGTGGGCGGTAAGGATCCGGGCAGCTGGACAACCGACTCCACCGAGGTTTACCAGGAGGGGCTG
CAGTTTCCCTGCATTAAAATATTCGAAGGCGGCAAGCCAATCCAGAGTCTGGTGGATCTCATCGCCGCCAACGTGCGCAT
GCCGGATATGACCCTGGGGGACCTCTGGGCCGGGGTCGCCGCCCTGCGGGTGGGCGAGAGACGGTTCGTGGAGCTCTGCG
ATAAATACGGCAAGGACCTGGTCCTGGCCAGCATCGAGCAGCTCCTGGACAACGGGGAGCGGCTGGTACGCCTGGAATTA
GCCAAATTGCCCAAGGGCGTGTACGAGGCTGAAGACTACATCGATGATGACGGCCTGGGTAACGGCCCCTTCCGGGTCTG
CGTCAAAGTGACCATTACTGACGACGAGTTCATCTGTGACTTCCGGGGCACCCATCCCCAGGTGCCCGGGCCGGTGAATT
GTAGCTATACCGGCCTGGTGGCCGGGGCGCGGTGCATCTTTAAGGCCATTACCAACCCGGCCATACCTGCCAATGAGGGG
ACCTTCCGGCCCCTGAAGATCATTACCGAGCCCCGGACCATTTTTACGGCCGAGCGGCCTGCCGCCGTCTCCACCTACTG
GGAGACTATGCTCTACGTCACCGATCTCATCTGGAAGGCCCTGGCGCCGGCGATACCGGAGCGCTTAACTGCTGGGCACT
TCCTCAGCGTCTGCGCCGATGTCCTGGCCAATATCCACCCCGACACCGGCGAACTGGCCCTCCTGGTGGAACCAACGGCC
GGGGGATGGGGCGCCGGCAAGTATAAAGACGGCGAGAACGGCATGGTCTGCATCGGCGACGGTGAAACTTATATTATTCC
GGTGGAGGTCGCCGAAACACGTTACGGTTTTCTGGTCGACCAGTACGCTTTAAATACCGCCGGTGGCGGTGCCGGCGAGA
AGCGTGGCGGCACAGGGGTCATCCGCGACTATCGCATCCTGGCTGATGAGGCCTACTTCACCGCCACCTTCGGCCGGCAC
AAGTTCCTGCCCTGGGGTATGGACGGTGGCAAACCGGGCACGCGGAACGAAGTGCGGGTTATTTCAGCCCACGGTGAACC
GGAACGGGTCTTTGGCAAGTGCGCCCGCCTGCGCCTGCGCCGGAACGATGTAGTCCGCCTGATTACCGGCTGCGGTGGAG
GATATGGCAACCCTTATCGCCGGCCGGTGGAGAAGGTCCAGGAGGATGTCCGCAACGGGTATATCACCCTGACCCAGGCC
TGGGAAGATTACGGTGTGCGCTTGAACCCCGAAACCCTGGCGGTCGAGGAACTGGCGCCCCAGCGGCAAGATAATAGAGC
AAAGGATTAG

Upstream 100 bases:

>100_bases
TGAAGAACCGGCCTCATCCACCCTCCTTTTCCCGGGCCAAAAGCTGACTGTCGATCCTTACGGCAACCTGATTATTGAAA
CGGGGGTGTAACCTGTAACT

Downstream 100 bases:

>100_bases
AGTAAAGGCCCGGTGCCGGTTTTTCCGGTCGCCGGGCTTTCTGGTTTTGCTTCGTTCACCGCCGCAAAGCTCTCGGCTTC
GCGTAAGTATCTGACGCCTC

Product: 5-oxoprolinase (ATP-hydrolyzing)

Products: ADP; phosphate; N-carbamoylsarcosine

Alternate protein names: NA

Number of amino acids: Translated: 589; Mature: 589

Protein sequence:

>589_residues
MEEKKRAGALRDVDPFTVEIIKDSLIAIGDEMFVALQRTSKSTIIYEVLDYACGLTDNQARLITQGNGVTGFLGTLDFSV
KDAINKFAARGLLNPGDVIITNDPYGGGGTHLSDVCLVMPIFYDGEIVAYSANKAHWTEVGGKDPGSWTTDSTEVYQEGL
QFPCIKIFEGGKPIQSLVDLIAANVRMPDMTLGDLWAGVAALRVGERRFVELCDKYGKDLVLASIEQLLDNGERLVRLEL
AKLPKGVYEAEDYIDDDGLGNGPFRVCVKVTITDDEFICDFRGTHPQVPGPVNCSYTGLVAGARCIFKAITNPAIPANEG
TFRPLKIITEPRTIFTAERPAAVSTYWETMLYVTDLIWKALAPAIPERLTAGHFLSVCADVLANIHPDTGELALLVEPTA
GGWGAGKYKDGENGMVCIGDGETYIIPVEVAETRYGFLVDQYALNTAGGGAGEKRGGTGVIRDYRILADEAYFTATFGRH
KFLPWGMDGGKPGTRNEVRVISAHGEPERVFGKCARLRLRRNDVVRLITGCGGGYGNPYRRPVEKVQEDVRNGYITLTQA
WEDYGVRLNPETLAVEELAPQRQDNRAKD

Sequences:

>Translated_589_residues
MEEKKRAGALRDVDPFTVEIIKDSLIAIGDEMFVALQRTSKSTIIYEVLDYACGLTDNQARLITQGNGVTGFLGTLDFSV
KDAINKFAARGLLNPGDVIITNDPYGGGGTHLSDVCLVMPIFYDGEIVAYSANKAHWTEVGGKDPGSWTTDSTEVYQEGL
QFPCIKIFEGGKPIQSLVDLIAANVRMPDMTLGDLWAGVAALRVGERRFVELCDKYGKDLVLASIEQLLDNGERLVRLEL
AKLPKGVYEAEDYIDDDGLGNGPFRVCVKVTITDDEFICDFRGTHPQVPGPVNCSYTGLVAGARCIFKAITNPAIPANEG
TFRPLKIITEPRTIFTAERPAAVSTYWETMLYVTDLIWKALAPAIPERLTAGHFLSVCADVLANIHPDTGELALLVEPTA
GGWGAGKYKDGENGMVCIGDGETYIIPVEVAETRYGFLVDQYALNTAGGGAGEKRGGTGVIRDYRILADEAYFTATFGRH
KFLPWGMDGGKPGTRNEVRVISAHGEPERVFGKCARLRLRRNDVVRLITGCGGGYGNPYRRPVEKVQEDVRNGYITLTQA
WEDYGVRLNPETLAVEELAPQRQDNRAKD
>Mature_589_residues
MEEKKRAGALRDVDPFTVEIIKDSLIAIGDEMFVALQRTSKSTIIYEVLDYACGLTDNQARLITQGNGVTGFLGTLDFSV
KDAINKFAARGLLNPGDVIITNDPYGGGGTHLSDVCLVMPIFYDGEIVAYSANKAHWTEVGGKDPGSWTTDSTEVYQEGL
QFPCIKIFEGGKPIQSLVDLIAANVRMPDMTLGDLWAGVAALRVGERRFVELCDKYGKDLVLASIEQLLDNGERLVRLEL
AKLPKGVYEAEDYIDDDGLGNGPFRVCVKVTITDDEFICDFRGTHPQVPGPVNCSYTGLVAGARCIFKAITNPAIPANEG
TFRPLKIITEPRTIFTAERPAAVSTYWETMLYVTDLIWKALAPAIPERLTAGHFLSVCADVLANIHPDTGELALLVEPTA
GGWGAGKYKDGENGMVCIGDGETYIIPVEVAETRYGFLVDQYALNTAGGGAGEKRGGTGVIRDYRILADEAYFTATFGRH
KFLPWGMDGGKPGTRNEVRVISAHGEPERVFGKCARLRLRRNDVVRLITGCGGGYGNPYRRPVEKVQEDVRNGYITLTQA
WEDYGVRLNPETLAVEELAPQRQDNRAKD

Specific function: Unknown

COG id: COG0146

COG function: function code EQ; N-methylhydantoinase B/acetone carboxylase, alpha subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

Organism=Homo sapiens, GI48314820, Length=547, Percent_Identity=29.6160877513711, Blast_Score=185, Evalue=8e-47,
Organism=Caenorhabditis elegans, GI133901900, Length=549, Percent_Identity=26.5938069216758, Blast_Score=169, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI133901902, Length=514, Percent_Identity=25.875486381323, Blast_Score=146, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6322634, Length=556, Percent_Identity=27.5179856115108, Blast_Score=159, Evalue=8e-40,
Organism=Drosophila melanogaster, GI45550492, Length=575, Percent_Identity=26.9565217391304, Blast_Score=164, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003692 [H]

Pfam domain/function: PF02538 Hydantoinase_B [H]

EC number: 3.5.2.14

Molecular weight: Translated: 64394; Mature: 64394

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEKKRAGALRDVDPFTVEIIKDSLIAIGDEMFVALQRTSKSTIIYEVLDYACGLTDNQA
CCCHHHCCCCCCCCCHHHHHHHHHHHHHCCHHEEEEECCCCCHHHHHHHHHHCCCCCCCC
RLITQGNGVTGFLGTLDFSVKDAINKFAARGLLNPGDVIITNDPYGGGGTHLSDVCLVMP
EEEECCCCCEEEEEEECHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCHHCCCEEEE
IFYDGEIVAYSANKAHWTEVGGKDPGSWTTDSTEVYQEGLQFPCIKIFEGGKPIQSLVDL
EEECCEEEEEECCCCEEEECCCCCCCCCCCCCHHHHHCCCCCCEEEEECCCCHHHHHHHH
IAANVRMPDMTLGDLWAGVAALRVGERRFVELCDKYGKDLVLASIEQLLDNGERLVRLEL
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEEH
AKLPKGVYEAEDYIDDDGLGNGPFRVCVKVTITDDEFICDFRGTHPQVPGPVNCSYTGLV
HHCCCCHHHHHHCCCCCCCCCCCEEEEEEEEECCCCEEEECCCCCCCCCCCCCCCCHHHH
AGARCIFKAITNPAIPANEGTFRPLKIITEPRTIFTAERPAAVSTYWETMLYVTDLIWKA
HHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHHH
LAPAIPERLTAGHFLSVCADVLANIHPDTGELALLVEPTAGGWGAGKYKDGENGMVCIGD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEC
GETYIIPVEVAETRYGFLVDQYALNTAGGGAGEKRGGTGVIRDYRILADEAYFTATFGRH
CCEEEEEEEECCCCCCEEEEHHHHCCCCCCCCCCCCCCCCEEEEEEEECCCEEEEECCCC
KFLPWGMDGGKPGTRNEVRVISAHGEPERVFGKCARLRLRRNDVVRLITGCGGGYGNPYR
CCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHH
RPVEKVQEDVRNGYITLTQAWEDYGVRLNPETLAVEELAPQRQDNRAKD
HHHHHHHHHHHCCEEEEEEEHHHCCCEECCHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MEEKKRAGALRDVDPFTVEIIKDSLIAIGDEMFVALQRTSKSTIIYEVLDYACGLTDNQA
CCCHHHCCCCCCCCCHHHHHHHHHHHHHCCHHEEEEECCCCCHHHHHHHHHHCCCCCCCC
RLITQGNGVTGFLGTLDFSVKDAINKFAARGLLNPGDVIITNDPYGGGGTHLSDVCLVMP
EEEECCCCCEEEEEEECHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCHHCCCEEEE
IFYDGEIVAYSANKAHWTEVGGKDPGSWTTDSTEVYQEGLQFPCIKIFEGGKPIQSLVDL
EEECCEEEEEECCCCEEEECCCCCCCCCCCCCHHHHHCCCCCCEEEEECCCCHHHHHHHH
IAANVRMPDMTLGDLWAGVAALRVGERRFVELCDKYGKDLVLASIEQLLDNGERLVRLEL
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEEH
AKLPKGVYEAEDYIDDDGLGNGPFRVCVKVTITDDEFICDFRGTHPQVPGPVNCSYTGLV
HHCCCCHHHHHHCCCCCCCCCCCEEEEEEEEECCCCEEEECCCCCCCCCCCCCCCCHHHH
AGARCIFKAITNPAIPANEGTFRPLKIITEPRTIFTAERPAAVSTYWETMLYVTDLIWKA
HHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHHH
LAPAIPERLTAGHFLSVCADVLANIHPDTGELALLVEPTAGGWGAGKYKDGENGMVCIGD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEC
GETYIIPVEVAETRYGFLVDQYALNTAGGGAGEKRGGTGVIRDYRILADEAYFTATFGRH
CCEEEEEEEECCCCCCEEEEHHHHCCCCCCCCCCCCCCCCEEEEEEEECCCEEEEECCCC
KFLPWGMDGGKPGTRNEVRVISAHGEPERVFGKCARLRLRRNDVVRLITGCGGGYGNPYR
CCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHH
RPVEKVQEDVRNGYITLTQAWEDYGVRLNPETLAVEELAPQRQDNRAKD
HHHHHHHHHHHCCEEEEEEEHHHCCCEECCHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; N-methylimidazolidine-2,4-dione; H2O

Specific reaction: ATP + N-methylimidazolidine-2,4-dione + 2 H2O = ADP + phosphate + N-carbamoylsarcosine

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]