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The map label for this gene is 83590799

Identifier: 83590799

GI number: 83590799

Start: 2049345

End: 2051396

Strand: Reverse

Name: 83590799

Synonym: Moth_1967

Alternate gene names: NA

Gene position: 2051396-2049345 (Counterclockwise)

Preceding gene: 83590800

Following gene: 83590798

Centisome position: 78.04

GC content: 58.92

Gene sequence:

>2052_bases
ATGCGTGTCGCTACCGACATTGGCGGTACCTTTACCGACCTGGTCTATCTGGATGAGGATACCGGCCGGGTAGGGGTAGC
CAAAACAGATACCACCCCGCCGGAGTTTGAGCAGGGGGTAATCAACGCCATCAAGAAAGCCGGCTTAACGGAGACGGGGA
TAAATTTTTTTGTCCACGGCACTACCGTTATAATCAACGCCCTGACGGAGCGTAAAGGGGCCAAGACCGGCCTCATTACC
ACCAGGGGATTCCGCGACGTCCTCGAATTGGGGCGGTCCAACCGGGCGGATATTTACAATGTGTACTATAAAAAGCCCGT
TCCCTTTGTGCCCCGTTACCTGCGGCTGGAGGTAGAAGAACGCATCAACTACAAGGGCGAGGTCCTCGTCCCCTTAAAGG
AAGATGACGTGCGGCGCTGTATCGCCCAGTTTAAAAAAGAAGGCGTGGAAGCCATTGGCATTTGTTTCCTTCACTCTTAC
GCCAACCCCGAGCATGAGCGCCGGTGCGCGGAGATTATCCGCCGCGAGTGGCCGGAAGTAGATATCACCGTTTCCCACGA
GATCAGCAAAGAATGGCGCGAGTACGAGCGGACCAGCACCGCCGTCCTTAACAGTTATGTACAACCTGTAGCCGCCAGGT
ATATCGACTCCCTGGACCGGGAATTAAATAAACTCCAGGTCAGTAACAGGCGCTACATCATGCAGTCCAACGGTGGCACC
ACTTCCTTTGCCCGGGCGAAGGAAGCGCCCATCAACATGGTCGAATCCGGGCCGGTGGCCGGCGTCTTCGGCGCGGCCAC
CCTGGGAAAGCTGATCGGAGAAAAGAATATCATCGCCCTGGATATCGGCGGGACCACCGCCAAGTGCTCGCTGATCGAGA
ACGGCGAGATGAAGGTGACTACCGACTACAAGATCGAGTGGTCGCGGGAGTCCGCCGGGTATCCCATTAAAATCCCTGTG
GTAGATATTATTGAAATCGGCGCCGGCGGCGGGAGCATCGCCTGGATTGATGACGCCGGATCCTTGCACGTCGGCCCCCG
AAGCGCCGGCGCCCTGCCCGGGCCGGTAGCCTACGGCCGCGGCGGCACCGAACCAACGGTGACCGACGCCAACCTGATTG
CCGGCCGGATCAACCCGGAGTACTTCCTGGGGGGAGAGATTAAAGTCGATCTGGCAGGGGCCAGGGAGGCCATGGCCAGG
ATTGCCGCCCCTTTCAACCTGACTGTCGAGGACGCCGCCCTGGGGGTCATCCGCCTGGCCAACGCCAACATGATCAATGC
CTTGAAACTCATCTCCGTCCGGCGGGGTTATGACCCCCGCGACTTTACCCTGGTGGCTTTTGGCGGCGGCGGTTCCATGC
ACGCCGCGGCCCTGGCCCGGGAGTTAAAGATCAAGAGGGTTTTAATTCCCGTAGCCACGTCCGTCTTCTCCGCCTGGGGC
ATGCTGATGACCGATCTGCGGTACGATTTGATCCAGACGACCATCCGCCGGACCAATAGCATCACCCCGGTGGAATTGCA
GGCCATCTGGGATTCCCTGGAGAAGGAGGCGGTCCGGTACTTCCAGCAGGAAAACTTGGGGACTACCGATCTGGTCTTCT
CCCGTTTTGCCGATATGCGCTACCTGGGCCAGGAACATACAGTTAAAGTGCCCGTACCCGGCGGCAGGCTCGATGCCGCG
GCCATCAAAGAGATCGAAGAGCGCTTCCATGCCCTCCACGAACAACACTACACCTTCCGGCTGGAGGATTCCCAGATTGA
ATTTGTGAATTTCCACCTGACCACCTTCGGCAGGGTGAAGAAGCCGGAACTGGCCCGGCTGCAAACCGGCTCCGCCGACG
CTACCAGGGCCCTAAAGGGACATCGCCCGGTCCACTTCGATGCGGAAGGCTGGCAGGAGAGCGCTATTTATGAACGGAGC
CTCTTAGGTGCCGGGGCGACCATCACCGGCCCGGCGGTAGTTGAAGAACCGGCCTCATCCACCCTCCTTTTCCCGGGCCA
AAAGCTGACTGTCGATCCTTACGGCAACCTGATTATTGAAACGGGGGTGTAA

Upstream 100 bases:

>100_bases
AAGCAGGAAAAGGCAATAATTTTGTAGAAACCCATAGAAGTTAGGAAGGATAATAGTAAAACCTGTAACTAGCAGGGTCC
AGAAAGGAAGGGAAATCGGC

Downstream 100 bases:

>100_bases
CCTGTAACTATGGAAGAGAAGAAACGCGCCGGCGCCCTGCGGGATGTTGATCCCTTTACCGTGGAAATTATCAAGGATTC
CCTGATAGCCATTGGCGATG

Product: 5-oxoprolinase (ATP-hydrolyzing)

Products: ADP; phosphate; N-carbamoylsarcosine

Alternate protein names: NA

Number of amino acids: Translated: 683; Mature: 683

Protein sequence:

>683_residues
MRVATDIGGTFTDLVYLDEDTGRVGVAKTDTTPPEFEQGVINAIKKAGLTETGINFFVHGTTVIINALTERKGAKTGLIT
TRGFRDVLELGRSNRADIYNVYYKKPVPFVPRYLRLEVEERINYKGEVLVPLKEDDVRRCIAQFKKEGVEAIGICFLHSY
ANPEHERRCAEIIRREWPEVDITVSHEISKEWREYERTSTAVLNSYVQPVAARYIDSLDRELNKLQVSNRRYIMQSNGGT
TSFARAKEAPINMVESGPVAGVFGAATLGKLIGEKNIIALDIGGTTAKCSLIENGEMKVTTDYKIEWSRESAGYPIKIPV
VDIIEIGAGGGSIAWIDDAGSLHVGPRSAGALPGPVAYGRGGTEPTVTDANLIAGRINPEYFLGGEIKVDLAGAREAMAR
IAAPFNLTVEDAALGVIRLANANMINALKLISVRRGYDPRDFTLVAFGGGGSMHAAALARELKIKRVLIPVATSVFSAWG
MLMTDLRYDLIQTTIRRTNSITPVELQAIWDSLEKEAVRYFQQENLGTTDLVFSRFADMRYLGQEHTVKVPVPGGRLDAA
AIKEIEERFHALHEQHYTFRLEDSQIEFVNFHLTTFGRVKKPELARLQTGSADATRALKGHRPVHFDAEGWQESAIYERS
LLGAGATITGPAVVEEPASSTLLFPGQKLTVDPYGNLIIETGV

Sequences:

>Translated_683_residues
MRVATDIGGTFTDLVYLDEDTGRVGVAKTDTTPPEFEQGVINAIKKAGLTETGINFFVHGTTVIINALTERKGAKTGLIT
TRGFRDVLELGRSNRADIYNVYYKKPVPFVPRYLRLEVEERINYKGEVLVPLKEDDVRRCIAQFKKEGVEAIGICFLHSY
ANPEHERRCAEIIRREWPEVDITVSHEISKEWREYERTSTAVLNSYVQPVAARYIDSLDRELNKLQVSNRRYIMQSNGGT
TSFARAKEAPINMVESGPVAGVFGAATLGKLIGEKNIIALDIGGTTAKCSLIENGEMKVTTDYKIEWSRESAGYPIKIPV
VDIIEIGAGGGSIAWIDDAGSLHVGPRSAGALPGPVAYGRGGTEPTVTDANLIAGRINPEYFLGGEIKVDLAGAREAMAR
IAAPFNLTVEDAALGVIRLANANMINALKLISVRRGYDPRDFTLVAFGGGGSMHAAALARELKIKRVLIPVATSVFSAWG
MLMTDLRYDLIQTTIRRTNSITPVELQAIWDSLEKEAVRYFQQENLGTTDLVFSRFADMRYLGQEHTVKVPVPGGRLDAA
AIKEIEERFHALHEQHYTFRLEDSQIEFVNFHLTTFGRVKKPELARLQTGSADATRALKGHRPVHFDAEGWQESAIYERS
LLGAGATITGPAVVEEPASSTLLFPGQKLTVDPYGNLIIETGV
>Mature_683_residues
MRVATDIGGTFTDLVYLDEDTGRVGVAKTDTTPPEFEQGVINAIKKAGLTETGINFFVHGTTVIINALTERKGAKTGLIT
TRGFRDVLELGRSNRADIYNVYYKKPVPFVPRYLRLEVEERINYKGEVLVPLKEDDVRRCIAQFKKEGVEAIGICFLHSY
ANPEHERRCAEIIRREWPEVDITVSHEISKEWREYERTSTAVLNSYVQPVAARYIDSLDRELNKLQVSNRRYIMQSNGGT
TSFARAKEAPINMVESGPVAGVFGAATLGKLIGEKNIIALDIGGTTAKCSLIENGEMKVTTDYKIEWSRESAGYPIKIPV
VDIIEIGAGGGSIAWIDDAGSLHVGPRSAGALPGPVAYGRGGTEPTVTDANLIAGRINPEYFLGGEIKVDLAGAREAMAR
IAAPFNLTVEDAALGVIRLANANMINALKLISVRRGYDPRDFTLVAFGGGGSMHAAALARELKIKRVLIPVATSVFSAWG
MLMTDLRYDLIQTTIRRTNSITPVELQAIWDSLEKEAVRYFQQENLGTTDLVFSRFADMRYLGQEHTVKVPVPGGRLDAA
AIKEIEERFHALHEQHYTFRLEDSQIEFVNFHLTTFGRVKKPELARLQTGSADATRALKGHRPVHFDAEGWQESAIYERS
LLGAGATITGPAVVEEPASSTLLFPGQKLTVDPYGNLIIETGV

Specific function: Unknown

COG id: COG0145

COG function: function code EQ; N-methylhydantoinase A/acetone carboxylase, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

Organism=Homo sapiens, GI48314820, Length=736, Percent_Identity=27.7173913043478, Blast_Score=218, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI133901900, Length=718, Percent_Identity=25.7660167130919, Blast_Score=195, Evalue=7e-50,
Organism=Saccharomyces cerevisiae, GI6322634, Length=749, Percent_Identity=27.5033377837116, Blast_Score=236, Evalue=1e-62,
Organism=Drosophila melanogaster, GI45550492, Length=734, Percent_Identity=30.2452316076294, Blast_Score=263, Evalue=4e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008040
- InterPro:   IPR002821 [H]

Pfam domain/function: PF05378 Hydant_A_N; PF01968 Hydantoinase_A [H]

EC number: 3.5.2.14

Molecular weight: Translated: 75142; Mature: 75142

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVATDIGGTFTDLVYLDEDTGRVGVAKTDTTPPEFEQGVINAIKKAGLTETGINFFVHG
CEEECCCCCCEEEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEC
TTVIINALTERKGAKTGLITTRGFRDVLELGRSNRADIYNVYYKKPVPFVPRYLRLEVEE
HHHEEEHHHHCCCCCCCEEEECCHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHEEEEHH
RINYKGEVLVPLKEDDVRRCIAQFKKEGVEAIGICFLHSYANPEHERRCAEIIRREWPEV
HCCCCCCEEEECCHHHHHHHHHHHHHCCCHHEEHHEEHHCCCCHHHHHHHHHHHHCCCCE
DITVSHEISKEWREYERTSTAVLNSYVQPVAARYIDSLDRELNKLQVSNRRYIMQSNGGT
EEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEECCCCC
TSFARAKEAPINMVESGPVAGVFGAATLGKLIGEKNIIALDIGGTTAKCSLIENGEMKVT
CHHHHCCCCCCCEECCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEECCCEEEE
TDYKIEWSRESAGYPIKIPVVDIIEIGAGGGSIAWIDDAGSLHVGPRSAGALPGPVAYGR
EEEEEEECCCCCCCEEEECEEEEEEECCCCCCEEEEECCCCEEECCCCCCCCCCCCCCCC
GGTEPTVTDANLIAGRINPEYFLGGEIKVDLAGAREAMARIAAPFNLTVEDAALGVIRLA
CCCCCCEECCCEEEECCCCCEEECCEEEEEECCHHHHHHHHCCCCCEEEHHHHEEEEEEC
NANMINALKLISVRRGYDPRDFTLVAFGGGGSMHAAALARELKIKRVLIPVATSVFSAWG
CCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLMTDLRYDLIQTTIRRTNSITPVELQAIWDSLEKEAVRYFQQENLGTTDLVFSRFADMR
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
YLGQEHTVKVPVPGGRLDAAAIKEIEERFHALHEQHYTFRLEDSQIEFVNFHLTTFGRVK
HCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCEEEEEEEEEEECCCCC
KPELARLQTGSADATRALKGHRPVHFDAEGWQESAIYERSLLGAGATITGPAVVEEPASS
CCCHHHCCCCCCHHHHHHCCCCCEEECCCCCHHHHHHHHHHHCCCCEECCCHHCCCCCCC
TLLFPGQKLTVDPYGNLIIETGV
EEEECCCEEEECCCCCEEEECCC
>Mature Secondary Structure
MRVATDIGGTFTDLVYLDEDTGRVGVAKTDTTPPEFEQGVINAIKKAGLTETGINFFVHG
CEEECCCCCCEEEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEC
TTVIINALTERKGAKTGLITTRGFRDVLELGRSNRADIYNVYYKKPVPFVPRYLRLEVEE
HHHEEEHHHHCCCCCCCEEEECCHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHEEEEHH
RINYKGEVLVPLKEDDVRRCIAQFKKEGVEAIGICFLHSYANPEHERRCAEIIRREWPEV
HCCCCCCEEEECCHHHHHHHHHHHHHCCCHHEEHHEEHHCCCCHHHHHHHHHHHHCCCCE
DITVSHEISKEWREYERTSTAVLNSYVQPVAARYIDSLDRELNKLQVSNRRYIMQSNGGT
EEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEECCCCC
TSFARAKEAPINMVESGPVAGVFGAATLGKLIGEKNIIALDIGGTTAKCSLIENGEMKVT
CHHHHCCCCCCCEECCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEECCCEEEE
TDYKIEWSRESAGYPIKIPVVDIIEIGAGGGSIAWIDDAGSLHVGPRSAGALPGPVAYGR
EEEEEEECCCCCCCEEEECEEEEEEECCCCCCEEEEECCCCEEECCCCCCCCCCCCCCCC
GGTEPTVTDANLIAGRINPEYFLGGEIKVDLAGAREAMARIAAPFNLTVEDAALGVIRLA
CCCCCCEECCCEEEECCCCCEEECCEEEEEECCHHHHHHHHCCCCCEEEHHHHEEEEEEC
NANMINALKLISVRRGYDPRDFTLVAFGGGGSMHAAALARELKIKRVLIPVATSVFSAWG
CCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLMTDLRYDLIQTTIRRTNSITPVELQAIWDSLEKEAVRYFQQENLGTTDLVFSRFADMR
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
YLGQEHTVKVPVPGGRLDAAAIKEIEERFHALHEQHYTFRLEDSQIEFVNFHLTTFGRVK
HCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCEEEEEEEEEEECCCCC
KPELARLQTGSADATRALKGHRPVHFDAEGWQESAIYERSLLGAGATITGPAVVEEPASS
CCCHHHCCCCCCHHHHHHCCCCCEEECCCCCHHHHHHHHHHHCCCCEECCCHHCCCCCCC
TLLFPGQKLTVDPYGNLIIETGV
EEEECCCEEEECCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; N-methylimidazolidine-2,4-dione; H2O

Specific reaction: ATP + N-methylimidazolidine-2,4-dione + 2 H2O = ADP + phosphate + N-carbamoylsarcosine

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]