Click here to switch to the map view.

The map label for this gene is pncB2 [H]

Identifier: 83590670

GI number: 83590670

Start: 1893633

End: 1894673

Strand: Reverse

Name: pncB2 [H]

Synonym: Moth_1836

Alternate gene names: 83590670

Gene position: 1894673-1893633 (Counterclockwise)

Preceding gene: 83590671

Following gene: 83590669

Centisome position: 72.07

GC content: 63.3

Gene sequence:

>1041_bases
ATGGGGACCGAGGTCATCACTTCCCTGGAGCAGGTACAACAATTAGAGGTCAAACCGGACCGGCGGTTCTATTCGGCCGA
GCACGGGGAGATTGCCAGCGGGGCGACTACGGATATTTATTTTGTCCGCACCTATGAGATTCTTAAAAGCCTGGGCAAGG
TCGACACGGTAGTTACGGCCGAGATCTTTCCCCGCCGGGCCGGGATCCTCTGCGGGGTCAACGAGGTCCTGGAGCTTTTG
CGGGACAAAAAGGTGACCGTTTACGGCCTGCCGGAGGGGAGCCCCTTTGAGCCGAAAGAGGTGGTCATGCGCATCCAGGG
TCCCTATAGCGAGTTTGGCCTCTTTGAAACTACCTTGCTGGGAATGCTGGCCAGCTCCAGCGGCTGGGCTACGGCGGCCC
GGGAAATCAGGGAAGCGGCTGGTGAACATCCCTTTGTCTGCTTCGGGGCGCGCCACGTTCACCCGGCGGTGGCGCCGGTC
ATGGAGCGGGCGGCCATTGTCGGCGGCGCCGACGGGGCGAGTTGCATCCTGGCGGCCAAACTGGCCGGCCGGGAGCCCCA
GGGAACGGTACCCCATGCGGTATTCCTGATCATCGGCGATACAGTCGAGGGGGCCCTGGCCTACGACCGCCTCATGCCCC
CTGACGCCAAGCGGACCATCCTGATCGACACCTTTAAAGATGAGGCTGAAGAGGCCCTGCGGGTAGCCAGTGCCCTGGGG
CCGGCCCTGGCCGGGGTACGTTTGGATACCCCCAGCGAGCGAGGCGGCGTCACCCCGGAACTGGTCCGGGAAGTGCGCTA
TCGCCTGGATATGGCCGGCTTTAACCATGTGGGGATTTTTGTCTCCGGAGGCCTGACGCCGGAACGTATCCGGACCCTTA
TCGAAGCCGGGGCCGACGCCTTCGGCGTGGGCAGCTATATTTCCGGCGCGGCCCCCATTGATATGACCATGGACTTAAAG
GAGGTCGACGGCCGCCCGGTGGCCAAACGCGGCCGCCTGCCGGGGATCATTCCCAATCCCCGGCTGGTGCAGTTGAAATA
G

Upstream 100 bases:

>100_bases
TTATATTCTGACGTTCGCTAGCAGGGAATCGCCGCCGGAGGCCGAATAATATAGGGAAACCTCTGGTAAAATGAATTCTG
GCGTCGAGGAGTGGATACTA

Downstream 100 bases:

>100_bases
CCCCGGCGGGCCGGCAGGGGATATAAACCCGGCAATTACTTGACAGGAACAGCAGGAGAGTTTATAATAAACCTTGCCAA
ATGCGGCGATGGCGGAACCG

Product: nicotinate phosphoribosyltransferase

Products: NA

Alternate protein names: NAPRTase pncB2 [H]

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MGTEVITSLEQVQQLEVKPDRRFYSAEHGEIASGATTDIYFVRTYEILKSLGKVDTVVTAEIFPRRAGILCGVNEVLELL
RDKKVTVYGLPEGSPFEPKEVVMRIQGPYSEFGLFETTLLGMLASSSGWATAAREIREAAGEHPFVCFGARHVHPAVAPV
MERAAIVGGADGASCILAAKLAGREPQGTVPHAVFLIIGDTVEGALAYDRLMPPDAKRTILIDTFKDEAEEALRVASALG
PALAGVRLDTPSERGGVTPELVREVRYRLDMAGFNHVGIFVSGGLTPERIRTLIEAGADAFGVGSYISGAAPIDMTMDLK
EVDGRPVAKRGRLPGIIPNPRLVQLK

Sequences:

>Translated_346_residues
MGTEVITSLEQVQQLEVKPDRRFYSAEHGEIASGATTDIYFVRTYEILKSLGKVDTVVTAEIFPRRAGILCGVNEVLELL
RDKKVTVYGLPEGSPFEPKEVVMRIQGPYSEFGLFETTLLGMLASSSGWATAAREIREAAGEHPFVCFGARHVHPAVAPV
MERAAIVGGADGASCILAAKLAGREPQGTVPHAVFLIIGDTVEGALAYDRLMPPDAKRTILIDTFKDEAEEALRVASALG
PALAGVRLDTPSERGGVTPELVREVRYRLDMAGFNHVGIFVSGGLTPERIRTLIEAGADAFGVGSYISGAAPIDMTMDLK
EVDGRPVAKRGRLPGIIPNPRLVQLK
>Mature_345_residues
GTEVITSLEQVQQLEVKPDRRFYSAEHGEIASGATTDIYFVRTYEILKSLGKVDTVVTAEIFPRRAGILCGVNEVLELLR
DKKVTVYGLPEGSPFEPKEVVMRIQGPYSEFGLFETTLLGMLASSSGWATAAREIREAAGEHPFVCFGARHVHPAVAPVM
ERAAIVGGADGASCILAAKLAGREPQGTVPHAVFLIIGDTVEGALAYDRLMPPDAKRTILIDTFKDEAEEALRVASALGP
ALAGVRLDTPSERGGVTPELVREVRYRLDMAGFNHVGIFVSGGLTPERIRTLIEAGADAFGVGSYISGAAPIDMTMDLKE
VDGRPVAKRGRLPGIIPNPRLVQLK

Specific function: Catalyzes the conversion of nicotinic acid (NA) to NA mononucleotide (NaMN) [H]

COG id: COG1488

COG function: function code H; Nicotinic acid phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAPRTase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015977
- InterPro:   IPR007229
- InterPro:   IPR006405
- InterPro:   IPR002638 [H]

Pfam domain/function: PF04095 NAPRTase [H]

EC number: =2.4.2.11 [H]

Molecular weight: Translated: 37177; Mature: 37046

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTEVITSLEQVQQLEVKPDRRFYSAEHGEIASGATTDIYFVRTYEILKSLGKVDTVVTA
CCHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCEEEEEHHHHHHHHHCHHHHEEEH
EIFPRRAGILCGVNEVLELLRDKKVTVYGLPEGSPFEPKEVVMRIQGPYSEFGLFETTLL
HHHHCCCCEEECHHHHHHHHHCCCEEEEECCCCCCCCHHHHHEEECCCHHHHHHHHHHHH
GMLASSSGWATAAREIREAAGEHPFVCFGARHVHPAVAPVMERAAIVGGADGASCILAAK
HHHHCCCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHH
LAGREPQGTVPHAVFLIIGDTVEGALAYDRLMPPDAKRTILIDTFKDEAEEALRVASALG
HCCCCCCCCCCEEEEEEECCCCCHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHHH
PALAGVRLDTPSERGGVTPELVREVRYRLDMAGFNHVGIFVSGGLTPERIRTLIEAGADA
HHHCCCEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHCCCCC
FGVGSYISGAAPIDMTMDLKEVDGRPVAKRGRLPGIIPNPRLVQLK
CCCCHHHCCCCCCCEEECHHHCCCCCCHHCCCCCCCCCCCEEEEEC
>Mature Secondary Structure 
GTEVITSLEQVQQLEVKPDRRFYSAEHGEIASGATTDIYFVRTYEILKSLGKVDTVVTA
CHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCEEEEEHHHHHHHHHCHHHHEEEH
EIFPRRAGILCGVNEVLELLRDKKVTVYGLPEGSPFEPKEVVMRIQGPYSEFGLFETTLL
HHHHCCCCEEECHHHHHHHHHCCCEEEEECCCCCCCCHHHHHEEECCCHHHHHHHHHHHH
GMLASSSGWATAAREIREAAGEHPFVCFGARHVHPAVAPVMERAAIVGGADGASCILAAK
HHHHCCCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHH
LAGREPQGTVPHAVFLIIGDTVEGALAYDRLMPPDAKRTILIDTFKDEAEEALRVASALG
HCCCCCCCCCCEEEEEEECCCCCHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHHH
PALAGVRLDTPSERGGVTPELVREVRYRLDMAGFNHVGIFVSGGLTPERIRTLIEAGADA
HHHCCCEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHCCCCC
FGVGSYISGAAPIDMTMDLKEVDGRPVAKRGRLPGIIPNPRLVQLK
CCCCHHHCCCCCCCEEECHHHCCCCCCHHCCCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]