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The map label for this gene is yomI [H]

Identifier: 83590671

GI number: 83590671

Start: 1894753

End: 1895301

Strand: Reverse

Name: yomI [H]

Synonym: Moth_1837

Alternate gene names: 83590671

Gene position: 1895301-1894753 (Counterclockwise)

Preceding gene: 83590672

Following gene: 83590670

Centisome position: 72.1

GC content: 61.02

Gene sequence:

>549_bases
ATGGGTTTAGGAAGGCGTTTACTGTGGCTGCTTTTTTTGCTGGCCCTTCTCGCTTTTCTCCTGCCCCGGGCCGGCCGGTT
ACTTTATCCTTTACCCTACCGCGATAGTATTACGACCTACGCCCACCGGGAAGGGCTGGACCCACTGTTGGTGGCTGCCG
TAGCCAGGGTGGAAAGCAAGTTCGACCCCCGGGCCAGGTCCGAACAGGGGGCCATGGGTTTGATGCAGCTCATGCCGGAA
ACCGCCCGGCTGGCGGCGGGACACCTGGGTATGCCCTTTGCACCGGACAGGCTCTACGAGCCGGACTACAACCTGCGCCT
GGGCAGCTGGTACCTGGCCCGCCTTCTGGATGAATTTGGCGATGTCAACCCGGCCCTGGCGGCCTATAACGGCGGCCGCG
GCCACGTCCATGAGTGGCTGGATAGCGGCGTCTGGGACGGGAGTTACGGCAACCTGCGGCAGATACCCTTTCCCGAAACC
CGGGAGTTCGTCCGCAAGGTCCTGCGGGATTACCGTATCTATCGATTTTTATATTCTGACGTTCGCTAG

Upstream 100 bases:

>100_bases
CCACCGGCGGTGACCTGGAGGCTACCCGGGCTTCCGTCCGGGCGGCCTGGCAGGAACTGCAGCGCCACCTGGCAGATGAT
CCAGAGCCCGGAGGTGCCCC

Downstream 100 bases:

>100_bases
CAGGGAATCGCCGCCGGAGGCCGAATAATATAGGGAAACCTCTGGTAAAATGAATTCTGGCGTCGAGGAGTGGATACTAA
TGGGGACCGAGGTCATCACT

Product: lytic transglycosylase, catalytic

Products: 1,6-Anhydrobond [C]

Alternate protein names: NA

Number of amino acids: Translated: 182; Mature: 181

Protein sequence:

>182_residues
MGLGRRLLWLLFLLALLAFLLPRAGRLLYPLPYRDSITTYAHREGLDPLLVAAVARVESKFDPRARSEQGAMGLMQLMPE
TARLAAGHLGMPFAPDRLYEPDYNLRLGSWYLARLLDEFGDVNPALAAYNGGRGHVHEWLDSGVWDGSYGNLRQIPFPET
REFVRKVLRDYRIYRFLYSDVR

Sequences:

>Translated_182_residues
MGLGRRLLWLLFLLALLAFLLPRAGRLLYPLPYRDSITTYAHREGLDPLLVAAVARVESKFDPRARSEQGAMGLMQLMPE
TARLAAGHLGMPFAPDRLYEPDYNLRLGSWYLARLLDEFGDVNPALAAYNGGRGHVHEWLDSGVWDGSYGNLRQIPFPET
REFVRKVLRDYRIYRFLYSDVR
>Mature_181_residues
GLGRRLLWLLFLLALLAFLLPRAGRLLYPLPYRDSITTYAHREGLDPLLVAAVARVESKFDPRARSEQGAMGLMQLMPET
ARLAAGHLGMPFAPDRLYEPDYNLRLGSWYLARLLDEFGDVNPALAAYNGGRGHVHEWLDSGVWDGSYGNLRQIPFPETR
EFVRKVLRDYRIYRFLYSDVR

Specific function: Murein-Degrading Enzyme. Catalyzes The Cleavage Of The Glycosidic Bonds Between N-Acetylmuramic Acid And N- Acetylglucosamine Residues In Peptidoglycan. May Play A Role In Recycling Of Muropeptides During Cell Elongation And/Or Cell Division. [C]

COG id: COG0741

COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)

Gene ontology:

Cell location: Periplasmic Protein. Tightly Associated With The Murein Sacculus [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 10 TPR repeats [H]

Homologues:

Organism=Escherichia coli, GI87082441, Length=176, Percent_Identity=33.5227272727273, Blast_Score=88, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR008258
- InterPro:   IPR016047
- InterPro:   IPR010090
- InterPro:   IPR000189 [H]

Pfam domain/function: PF01551 Peptidase_M23; PF10145 PhageMin_Tail; PF01464 SLT [H]

EC number: 3.2.1.- [C]

Molecular weight: Translated: 20898; Mature: 20767

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: PS00922 TRANSGLYCOSYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLGRRLLWLLFLLALLAFLLPRAGRLLYPLPYRDSITTYAHREGLDPLLVAAVARVESK
CCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHH
FDPRARSEQGAMGLMQLMPETARLAAGHLGMPFAPDRLYEPDYNLRLGSWYLARLLDEFG
CCCCCCCHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHC
DVNPALAAYNGGRGHVHEWLDSGVWDGSYGNLRQIPFPETREFVRKVLRDYRIYRFLYSD
CCCCHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VR
CC
>Mature Secondary Structure 
GLGRRLLWLLFLLALLAFLLPRAGRLLYPLPYRDSITTYAHREGLDPLLVAAVARVESK
CCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHH
FDPRARSEQGAMGLMQLMPETARLAAGHLGMPFAPDRLYEPDYNLRLGSWYLARLLDEFG
CCCCCCCHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHC
DVNPALAAYNGGRGHVHEWLDSGVWDGSYGNLRQIPFPETREFVRKVLRDYRIYRFLYSD
CCCCHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VR
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]

General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]