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The map label for this gene is nuoG [C]

Identifier: 83590553

GI number: 83590553

Start: 1759099

End: 1760820

Strand: Reverse

Name: nuoG [C]

Synonym: Moth_1717

Alternate gene names: 83590553

Gene position: 1760820-1759099 (Counterclockwise)

Preceding gene: 83590554

Following gene: 83590552

Centisome position: 66.98

GC content: 60.34

Gene sequence:

>1722_bases
TTGAGCACCGTAAAACTGACCATTGACAATATACCGGTGGAAGTTGAGGCCGGAACGACGATCTTAAAGGCCGCCGAGGA
GGCTGGTATTCATATACCCACCCTTTGTTACCTGGAAGGCATCAACGAGATCGGCGCCTGCCGGGTCTGCGTGGTTGAAG
TTGAAGGGGCCAGGAACCTGATGGCCTCCTGTGTAGCCCCGGTAGCCGAAGGTATGGTGGTAAAGACCAACAGCCCGAGG
GTAAGGATGGCCCGGCGCCTGAACGTTGAGCTCCTCCTTTCCAACCACGAGATGGAGTGCCCGACCTGCATCCGTAACTT
GAACTGCGAACTCCAGTCCCTGGCCCGGGGGCTGGGTATCCGCCAGGTACGCTTTAAGGGCAAAAAGAGCGAGCACCCCG
TGGACGATTCGACCCCAGCCCTGGTGCGCGAGCCTGACAAGTGCATTCTCTGCCGCCGTTGCGTGGCCGTTTGCGAAAAG
GTCCAGGGAGTTATGGCTATAGCCCCCCTGGGGCGGGGCTTTGACACCGTCATCGCCCCGGCCTTCCAGGAGAAGCTCGT
GGACATCGCCTGCGTGGAATGCGGCCAGTGCACCCTTGTCTGCCCGGTGGGCGCCCTGTACGAAAAAGATTACACCAGCG
AAGTCTGGGCGGCCCTGGCCGACCCGGAGAAGTTCGTCGTCGTCCAGACGGCGCCGGCCACCCGGGTGTCCATCGGCCAG
GAGTTCGGGTTAGCACCGGGGAGCATCAACACCGGCCAGATGGTGGCGGCTTTAAGGCGCCTGGGCTTTGACAGGGTCTT
TGATACCGACTTTTCCGCCGACCTGACCATTATGGAAGAAGGCTCCGAGTTTATTGAGCGCTTTACCAAAGATGGCCCCC
TGCCGTTGATCACCTCCTGCAGCCCGGGCTGGATCAAGTTTATGGAGCACTTCTACCCGGAGCTTATACCCAACGTCTCC
ACCTGCAAGTCGCCCCAGCAGATGTTCGGCGCCGTGGCCAAGACTTACTATGCCCGGAAGGCCGGTGTAGATCCGGCCAG
GATGGTGGTCGTCTCCATCATGCCCTGCACTGCCAAGAAGTTCGAGTGCCAGCGGCCGGAGATGCGGGACAGCGGCTATC
AGGACGTGGACTACGTCCTCACCACGCGCGAGCTGGCGCGGATGATCAGGGAAGCCGGGATTGATTTCAAAAACCTCCCG
GAAGAGCAGTACGACGATCCATTAGGCGAATCCACCGGAGCGGGGGTCATCTTCGGTGCCACAGGCGGGGTCATGGAGGC
GGCCTTGCGTACGGCCTACGAACTAATTACCGGCGAGACCCTGCCCGCCCTGGACTTCTATGATATCCGCGGCCTCAAGG
GCATCAAGGAAGCCACGGTAGACATCAAGGGTACCAAAGTCCGGGTGGCTGTAGCCCACAGCCTGGGCCATGCCCGGCAG
CTTTTAGAGCGGGTCAAGGCCGGGGAGCAGTATCACTTCATTGAAATCATGTGCTGCCCCGGCGGCTGCATTGGCGGCGG
CGGGCAGCCCATCCCCACCAACACCGAGATCAGGGAGCAGCGCATCAAGGGTATTTATCAGGTCGACATGGAGATGCCCA
TCCGCAAGTCCCACGAGAACCCGTCCGTTCAAGCCCTTTACCGCGAGTTCCTGGGCAAGCCTTTGAGCGAGAAGTCCCAC
CACTTATTGCACACCGAATATACGCGGCGGGGGAAATACTAG

Upstream 100 bases:

>100_bases
ATTGATCCTGCAGCCTGCATTAAATGCGGCAGCTGTTATGAGAAATGCAGGTTCGGCGCCATAACGAGGGAATAACGGAG
GAAAACGGGAGGCGAACAAG

Downstream 100 bases:

>100_bases
AGAATCTTTTGCAGTTCGCCAGGACCTCCCCGGTTCTTTAAAAGCGCCGGGGAGGCCTTTTTATCTGGTCGAGAAGGAGA
AAGAGGTCTTGTGGCGAAAA

Product: Iron hydrogenase, small subunit

Products: NA

Alternate protein names: CpI; Fe-only hydrogenase; [Fe] hydrogenase [H]

Number of amino acids: Translated: 573; Mature: 572

Protein sequence:

>573_residues
MSTVKLTIDNIPVEVEAGTTILKAAEEAGIHIPTLCYLEGINEIGACRVCVVEVEGARNLMASCVAPVAEGMVVKTNSPR
VRMARRLNVELLLSNHEMECPTCIRNLNCELQSLARGLGIRQVRFKGKKSEHPVDDSTPALVREPDKCILCRRCVAVCEK
VQGVMAIAPLGRGFDTVIAPAFQEKLVDIACVECGQCTLVCPVGALYEKDYTSEVWAALADPEKFVVVQTAPATRVSIGQ
EFGLAPGSINTGQMVAALRRLGFDRVFDTDFSADLTIMEEGSEFIERFTKDGPLPLITSCSPGWIKFMEHFYPELIPNVS
TCKSPQQMFGAVAKTYYARKAGVDPARMVVVSIMPCTAKKFECQRPEMRDSGYQDVDYVLTTRELARMIREAGIDFKNLP
EEQYDDPLGESTGAGVIFGATGGVMEAALRTAYELITGETLPALDFYDIRGLKGIKEATVDIKGTKVRVAVAHSLGHARQ
LLERVKAGEQYHFIEIMCCPGGCIGGGGQPIPTNTEIREQRIKGIYQVDMEMPIRKSHENPSVQALYREFLGKPLSEKSH
HLLHTEYTRRGKY

Sequences:

>Translated_573_residues
MSTVKLTIDNIPVEVEAGTTILKAAEEAGIHIPTLCYLEGINEIGACRVCVVEVEGARNLMASCVAPVAEGMVVKTNSPR
VRMARRLNVELLLSNHEMECPTCIRNLNCELQSLARGLGIRQVRFKGKKSEHPVDDSTPALVREPDKCILCRRCVAVCEK
VQGVMAIAPLGRGFDTVIAPAFQEKLVDIACVECGQCTLVCPVGALYEKDYTSEVWAALADPEKFVVVQTAPATRVSIGQ
EFGLAPGSINTGQMVAALRRLGFDRVFDTDFSADLTIMEEGSEFIERFTKDGPLPLITSCSPGWIKFMEHFYPELIPNVS
TCKSPQQMFGAVAKTYYARKAGVDPARMVVVSIMPCTAKKFECQRPEMRDSGYQDVDYVLTTRELARMIREAGIDFKNLP
EEQYDDPLGESTGAGVIFGATGGVMEAALRTAYELITGETLPALDFYDIRGLKGIKEATVDIKGTKVRVAVAHSLGHARQ
LLERVKAGEQYHFIEIMCCPGGCIGGGGQPIPTNTEIREQRIKGIYQVDMEMPIRKSHENPSVQALYREFLGKPLSEKSH
HLLHTEYTRRGKY
>Mature_572_residues
STVKLTIDNIPVEVEAGTTILKAAEEAGIHIPTLCYLEGINEIGACRVCVVEVEGARNLMASCVAPVAEGMVVKTNSPRV
RMARRLNVELLLSNHEMECPTCIRNLNCELQSLARGLGIRQVRFKGKKSEHPVDDSTPALVREPDKCILCRRCVAVCEKV
QGVMAIAPLGRGFDTVIAPAFQEKLVDIACVECGQCTLVCPVGALYEKDYTSEVWAALADPEKFVVVQTAPATRVSIGQE
FGLAPGSINTGQMVAALRRLGFDRVFDTDFSADLTIMEEGSEFIERFTKDGPLPLITSCSPGWIKFMEHFYPELIPNVST
CKSPQQMFGAVAKTYYARKAGVDPARMVVVSIMPCTAKKFECQRPEMRDSGYQDVDYVLTTRELARMIREAGIDFKNLPE
EQYDDPLGESTGAGVIFGATGGVMEAALRTAYELITGETLPALDFYDIRGLKGIKEATVDIKGTKVRVAVAHSLGHARQL
LERVKAGEQYHFIEIMCCPGGCIGGGGQPIPTNTEIREQRIKGIYQVDMEMPIRKSHENPSVQALYREFLGKPLSEKSHH
LLHTEYTRRGKY

Specific function: Ndh-1 Shuttles Electrons From NADH, Via Fmn And Iron- Sulfur (Fe-S) Centers, To Quinones In The Respiratory Chain. The Immediate Electron Acceptor For The Enzyme In This Species Is Believed To Be Ubiquinone. Couples The Redox Reaction To Proton Translocat

COG id: COG4624

COG function: function code R; Iron only hydrogenase large subunit, C-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI11968051, Length=360, Percent_Identity=31.9444444444444, Blast_Score=183, Evalue=4e-46,
Organism=Homo sapiens, GI6912524, Length=362, Percent_Identity=27.9005524861878, Blast_Score=152, Evalue=1e-36,
Organism=Homo sapiens, GI134284357, Length=362, Percent_Identity=27.9005524861878, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI84452151, Length=363, Percent_Identity=27.8236914600551, Blast_Score=151, Evalue=2e-36,
Organism=Homo sapiens, GI14165461, Length=401, Percent_Identity=25.6857855361596, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI33519475, Length=222, Percent_Identity=35.5855855855856, Blast_Score=130, Evalue=4e-30,
Organism=Escherichia coli, GI145693161, Length=225, Percent_Identity=28, Blast_Score=97, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17565758, Length=220, Percent_Identity=38.1818181818182, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI32566231, Length=220, Percent_Identity=38.1818181818182, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI193209088, Length=220, Percent_Identity=38.1818181818182, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI71995015, Length=402, Percent_Identity=27.8606965174129, Blast_Score=122, Evalue=5e-28,
Organism=Saccharomyces cerevisiae, GI6324089, Length=371, Percent_Identity=24.5283018867925, Blast_Score=88, Evalue=4e-18,
Organism=Drosophila melanogaster, GI116007470, Length=324, Percent_Identity=30.5555555555556, Blast_Score=155, Evalue=9e-38,
Organism=Drosophila melanogaster, GI116007466, Length=324, Percent_Identity=30.5555555555556, Blast_Score=155, Evalue=9e-38,
Organism=Drosophila melanogaster, GI116007464, Length=324, Percent_Identity=30.5555555555556, Blast_Score=155, Evalue=1e-37,
Organism=Drosophila melanogaster, GI116007468, Length=324, Percent_Identity=30.5555555555556, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24640559, Length=214, Percent_Identity=37.8504672897196, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24640557, Length=214, Percent_Identity=37.8504672897196, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI116007462, Length=286, Percent_Identity=30.4195804195804, Blast_Score=130, Evalue=3e-30,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR009016
- InterPro:   IPR004108
- InterPro:   IPR003149
- InterPro:   IPR013352
- InterPro:   IPR001041 [H]

Pfam domain/function: PF02906 Fe_hyd_lg_C; PF02256 Fe_hyd_SSU [H]

EC number: =1.12.7.2 [H]

Molecular weight: Translated: 63079; Mature: 62948

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS00641 COMPLEX1_75K_1 ; PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN ; PS01047 HMA_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTVKLTIDNIPVEVEAGTTILKAAEEAGIHIPTLCYLEGINEIGACRVCVVEVEGARNL
CCEEEEEECCCCEEEECCCHHHHHHHHCCCCCCHHHHHHCCCCCCCEEEEEEEECCHHHH
MASCVAPVAEGMVVKTNSPRVRMARRLNVELLLSNHEMECPTCIRNLNCELQSLARGLGI
HHHHHHHHHCCEEEECCCCHHHHHHHCCEEEEECCCCCCCHHHHHHCCCCHHHHHHCCCC
RQVRFKGKKSEHPVDDSTPALVREPDKCILCRRCVAVCEKVQGVMAIAPLGRGFDTVIAP
EEEEECCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHH
AFQEKLVDIACVECGQCTLVCPVGALYEKDYTSEVWAALADPEKFVVVQTAPATRVSIGQ
HHHHHHHHHHHHCCCCEEEEECCHHHHHCCCHHHHHHHHCCCCEEEEEEECCCCHHCCCH
EFGLAPGSINTGQMVAALRRLGFDRVFDTDFSADLTIMEEGSEFIERFTKDGPLPLITSC
HHCCCCCCCCHHHHHHHHHHCCCCHHCCCCCCCCEEEECCCHHHHHHHHCCCCCCEEECC
SPGWIKFMEHFYPELIPNVSTCKSPQQMFGAVAKTYYARKAGVDPARMVVVSIMPCTAKK
CCHHHHHHHHHHHHHCCCCHHCCCHHHHHHHHHHHHHHHHCCCCHHHEEEEEECCCCCCC
FECQRPEMRDSGYQDVDYVLTTRELARMIREAGIDFKNLPEEQYDDPLGESTGAGVIFGA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHCCCHHHCCCCCCCCCCCEEEEEC
TGGVMEAALRTAYELITGETLPALDFYDIRGLKGIKEATVDIKGTKVRVAVAHSLGHARQ
CCHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCCHHHEEEECCCEEEEEEHHHHHHHHH
LLERVKAGEQYHFIEIMCCPGGCIGGGGQPIPTNTEIREQRIKGIYQVDMEMPIRKSHEN
HHHHHHCCCCEEEEEEEECCCCEECCCCCCCCCCHHHHHHHHCCEEEECCCCCHHCCCCC
PSVQALYREFLGKPLSEKSHHLLHTEYTRRGKY
CHHHHHHHHHHCCCCCCCCCCEEEHHHHHCCCC
>Mature Secondary Structure 
STVKLTIDNIPVEVEAGTTILKAAEEAGIHIPTLCYLEGINEIGACRVCVVEVEGARNL
CEEEEEECCCCEEEECCCHHHHHHHHCCCCCCHHHHHHCCCCCCCEEEEEEEECCHHHH
MASCVAPVAEGMVVKTNSPRVRMARRLNVELLLSNHEMECPTCIRNLNCELQSLARGLGI
HHHHHHHHHCCEEEECCCCHHHHHHHCCEEEEECCCCCCCHHHHHHCCCCHHHHHHCCCC
RQVRFKGKKSEHPVDDSTPALVREPDKCILCRRCVAVCEKVQGVMAIAPLGRGFDTVIAP
EEEEECCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHH
AFQEKLVDIACVECGQCTLVCPVGALYEKDYTSEVWAALADPEKFVVVQTAPATRVSIGQ
HHHHHHHHHHHHCCCCEEEEECCHHHHHCCCHHHHHHHHCCCCEEEEEEECCCCHHCCCH
EFGLAPGSINTGQMVAALRRLGFDRVFDTDFSADLTIMEEGSEFIERFTKDGPLPLITSC
HHCCCCCCCCHHHHHHHHHHCCCCHHCCCCCCCCEEEECCCHHHHHHHHCCCCCCEEECC
SPGWIKFMEHFYPELIPNVSTCKSPQQMFGAVAKTYYARKAGVDPARMVVVSIMPCTAKK
CCHHHHHHHHHHHHHCCCCHHCCCHHHHHHHHHHHHHHHHCCCCHHHEEEEEECCCCCCC
FECQRPEMRDSGYQDVDYVLTTRELARMIREAGIDFKNLPEEQYDDPLGESTGAGVIFGA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHCCCHHHCCCCCCCCCCCEEEEEC
TGGVMEAALRTAYELITGETLPALDFYDIRGLKGIKEATVDIKGTKVRVAVAHSLGHARQ
CCHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCCHHHEEEECCCEEEEEEHHHHHHHHH
LLERVKAGEQYHFIEIMCCPGGCIGGGGQPIPTNTEIREQRIKGIYQVDMEMPIRKSHEN
HHHHHHCCCCEEEEEEEECCCCEECCCCCCCCCCHHHHHHHHCCEEEECCCCCHHCCCCC
PSVQALYREFLGKPLSEKSHHLLHTEYTRRGKY
CHHHHHHHHHHCCCCCCCCCCEEEHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1911757; 9836629; 10529166 [H]