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The map label for this gene is hppA

Identifier: 83590196

GI number: 83590196

Start: 1394222

End: 1396240

Strand: Reverse

Name: hppA

Synonym: Moth_1349

Alternate gene names: 83590196

Gene position: 1396240-1394222 (Counterclockwise)

Preceding gene: 83590197

Following gene: 83590191

Centisome position: 53.11

GC content: 53.44

Gene sequence:

>2019_bases
ATGGAGCTTTTAGCACCACTGACAGGGATAGTGGCCTTGCTTTTTGCCTTTTACCTTACTAATAAAATTAATCGGTCAGA
TCCCGGGAATCCACGGATGCAGGAAATCGCTGTCGCCATCCATGAAGGCGCCATGGCCTTCCTTATGCGGGAATACCGAA
CTTTAATCTTTTTTGTCCTTGGCATGACGGCCTTGATTGTAGTTGCCGGCTTTATGACTAGGGGTGCTGAAAGCATGCAA
CCGGCAACAGCTATTGCCTATGTCGCCGGTACCCTTTGTTCTATTGGCGCCGGGTACATAGGTATGCAGGTTGCCACTAG
GGCCAACGTCCGCACGGCCAATGCCGCCCGTCACAGTTCCAATGCCGCCCTGGACATAGCCTTTTCCGGCGGTTCGGTTA
TGGGGATGGCGGTGGTAGGTCTGGGCCTTTTGGGTCTCGGGATTATTAATTATGTTTTTAAAAACCCGAGTATAGTTAAT
GGTTTCGCCCTGGGGGCCAGTTCTATAGCCCTTTTTGCCAGAGTCGGTGGCGGTATATACACCAAGGCCGCCGATGTCGG
TGCGGACTTGGTCGGCAAAGTAGAAGCAGGTATTCCTGAAGACGATCCCCGGAACCCAGCCGTTATTGCTGATAACGTTG
GTGACAATGTAGGCGACGTCGCCGGTATGGGTGCTGACCTCTTTGAGTCTTATGTCGGCTCGATTATTTCTGGTATTGCC
CTGGCGGCAGCCCTGAATATTCCTAATGGCACCTTGGTGCCTCTAATGATTGCTGCTATCGGCATTGTATCCTCCATTCT
CGGTGCCTTTTTCGTGAAAACGGGCGAAGGGGCCAATGCCCAGAAGGCTCTTAATACCGGTACCATGGTGGCAAGTATCC
TGGCCATTGTTGGTACTTTCCTGGCTACTAGGTTATTACCGGCTCACTTCACCGCTGGCTCTATGAGTTACACTTCTACA
GGCGTATTTGCAGCCACCATCGCCGGCCTCATCGCCGGAGTCTTGATTGGCCGGATTACCGAGTATTATACTTCAGGGGA
TTACGAACCTGTAAAAGAGATCGCCAAGGCTTCCCAAACCGGTACAGCTACCAACATTATTGAAGGCTTAAGCACCGGTA
TGCTGAGCACAGTTTTGCCTATCCTGGTCATCGTCATTGCCATTATCGCTTCTTACCGTTTCGCCGGCCTTTATGGTATT
GCTATGGCGGCGGTTGGCATGCTCTCGACCACCGGCACTACTGTGGCCGTTGATGCTTATGGTCCTATCGCCGATAATGC
TGGCGGTATTGCCGAAATGGCGGAACTGGACCCAAAGGTCCGTAAGATAACCGACGCCCTGGACTCCGTCGGCAACACAA
CGGCTGCCATTGGTAAGGGTTTTGCTATCGGTTCGGCGGCGCTGACGGCCCTGGCCTTATTCTCGGCCTATACAGCTGCT
GCCAGGATTACCGCCATTGACCTGACCGACCCCAAAGTAGTCGGCGGTCTCTTCATAGGTGGTATGCTGCCGTTTCTTTT
TGCTGCCTTAACTATGAAAGCGGTGGGTAGGGCTGCTTTCCAAATGATTGAAGAAGTACGCCGCCAGTTCAAATCGATTC
CCGGCTTAATGGAAGGCAAGGCCCGGCCGGACTACGCCCGCTGCGTGGCTATTAGCACCGGAGCCGCTATTAAGGAAATG
ATTGTTCCCGGCCTACTCGCCGTTCTGGTACCCCTGGCCGTGGGTCTCATCCCCGGCCTGGGTAAGGAGGCCTTGGGTGG
CCTTCTCGCCGGCGCCACGGTGACGGGTTTCTTGATGGCCGTCATGATGGCTAATGCCGGTGGTGCCTGGGATAATGCCA
AAAAGTATATTGAGGGCGGCCAGTACGGCGGTAAGGGTTCACCGGCCCACGCTGCCGCCGTCAATGGAGATACAGTGGGT
GATCCCTTTAAGGATACCTCTGGCCCGGCCATGAACATTCTTATTAAGCTAATGACCATTGTCTCCTTGGTTTTTGCCCC
CTTATTTATGCAGCTTTAG

Upstream 100 bases:

>100_bases
CTTCTCCAGGGCCATTCTTGGATTTTAACAGTTGGGAGGTTAAAAGGGAAATTTAGGTAATAACAAGAGGGGTTAAGTTT
AAATTTGGGGAGGCGGTCTT

Downstream 100 bases:

>100_bases
GGGGCGCATGCCTGCCGGCGCGTAATTCCTGATCAAAAGGAAAAAAGCCCTTCTCTCTTGGGAGACAAGGGCTTTTTATT
AGAGCTAGGTTTCCGGGGCA

Product: membrane-bound proton-translocating pyrophosphatase

Products: NA

Alternate protein names: Membrane-bound sodium-translocating pyrophosphatase; Pyrophosphate-energized inorganic pyrophosphatase; Na(+)-PPase

Number of amino acids: Translated: 672; Mature: 672

Protein sequence:

>672_residues
MELLAPLTGIVALLFAFYLTNKINRSDPGNPRMQEIAVAIHEGAMAFLMREYRTLIFFVLGMTALIVVAGFMTRGAESMQ
PATAIAYVAGTLCSIGAGYIGMQVATRANVRTANAARHSSNAALDIAFSGGSVMGMAVVGLGLLGLGIINYVFKNPSIVN
GFALGASSIALFARVGGGIYTKAADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDVAGMGADLFESYVGSIISGIA
LAAALNIPNGTLVPLMIAAIGIVSSILGAFFVKTGEGANAQKALNTGTMVASILAIVGTFLATRLLPAHFTAGSMSYTST
GVFAATIAGLIAGVLIGRITEYYTSGDYEPVKEIAKASQTGTATNIIEGLSTGMLSTVLPILVIVIAIIASYRFAGLYGI
AMAAVGMLSTTGTTVAVDAYGPIADNAGGIAEMAELDPKVRKITDALDSVGNTTAAIGKGFAIGSAALTALALFSAYTAA
ARITAIDLTDPKVVGGLFIGGMLPFLFAALTMKAVGRAAFQMIEEVRRQFKSIPGLMEGKARPDYARCVAISTGAAIKEM
IVPGLLAVLVPLAVGLIPGLGKEALGGLLAGATVTGFLMAVMMANAGGAWDNAKKYIEGGQYGGKGSPAHAAAVNGDTVG
DPFKDTSGPAMNILIKLMTIVSLVFAPLFMQL

Sequences:

>Translated_672_residues
MELLAPLTGIVALLFAFYLTNKINRSDPGNPRMQEIAVAIHEGAMAFLMREYRTLIFFVLGMTALIVVAGFMTRGAESMQ
PATAIAYVAGTLCSIGAGYIGMQVATRANVRTANAARHSSNAALDIAFSGGSVMGMAVVGLGLLGLGIINYVFKNPSIVN
GFALGASSIALFARVGGGIYTKAADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDVAGMGADLFESYVGSIISGIA
LAAALNIPNGTLVPLMIAAIGIVSSILGAFFVKTGEGANAQKALNTGTMVASILAIVGTFLATRLLPAHFTAGSMSYTST
GVFAATIAGLIAGVLIGRITEYYTSGDYEPVKEIAKASQTGTATNIIEGLSTGMLSTVLPILVIVIAIIASYRFAGLYGI
AMAAVGMLSTTGTTVAVDAYGPIADNAGGIAEMAELDPKVRKITDALDSVGNTTAAIGKGFAIGSAALTALALFSAYTAA
ARITAIDLTDPKVVGGLFIGGMLPFLFAALTMKAVGRAAFQMIEEVRRQFKSIPGLMEGKARPDYARCVAISTGAAIKEM
IVPGLLAVLVPLAVGLIPGLGKEALGGLLAGATVTGFLMAVMMANAGGAWDNAKKYIEGGQYGGKGSPAHAAAVNGDTVG
DPFKDTSGPAMNILIKLMTIVSLVFAPLFMQL
>Mature_672_residues
MELLAPLTGIVALLFAFYLTNKINRSDPGNPRMQEIAVAIHEGAMAFLMREYRTLIFFVLGMTALIVVAGFMTRGAESMQ
PATAIAYVAGTLCSIGAGYIGMQVATRANVRTANAARHSSNAALDIAFSGGSVMGMAVVGLGLLGLGIINYVFKNPSIVN
GFALGASSIALFARVGGGIYTKAADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDVAGMGADLFESYVGSIISGIA
LAAALNIPNGTLVPLMIAAIGIVSSILGAFFVKTGEGANAQKALNTGTMVASILAIVGTFLATRLLPAHFTAGSMSYTST
GVFAATIAGLIAGVLIGRITEYYTSGDYEPVKEIAKASQTGTATNIIEGLSTGMLSTVLPILVIVIAIIASYRFAGLYGI
AMAAVGMLSTTGTTVAVDAYGPIADNAGGIAEMAELDPKVRKITDALDSVGNTTAAIGKGFAIGSAALTALALFSAYTAA
ARITAIDLTDPKVVGGLFIGGMLPFLFAALTMKAVGRAAFQMIEEVRRQFKSIPGLMEGKARPDYARCVAISTGAAIKEM
IVPGLLAVLVPLAVGLIPGLGKEALGGLLAGATVTGFLMAVMMANAGGAWDNAKKYIEGGQYGGKGSPAHAAAVNGDTVG
DPFKDTSGPAMNILIKLMTIVSLVFAPLFMQL

Specific function: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane

COG id: COG3808

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HPPA1_MOOTA (Q2RIS7)

Other databases:

- EMBL:   CP000232
- RefSeq:   YP_430205.1
- STRING:   Q2RIS7
- GeneID:   3831907
- GenomeReviews:   CP000232_GR
- KEGG:   mta:Moth_1349
- NMPDR:   fig|264732.9.peg.1345
- eggNOG:   COG3808
- HOGENOM:   HBG593668
- OMA:   AYLARQY
- ProtClustDB:   PRK00733
- BioCyc:   MTHE264732:MOTH_1349-MONOMER
- HAMAP:   MF_01129
- InterPro:   IPR004131
- PIRSF:   PIRSF001265
- TIGRFAMs:   TIGR01104

Pfam domain/function: PF03030 H_PPase

EC number: =3.6.1.1

Molecular weight: Translated: 68450; Mature: 68450

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xf976dd4)-; HASH(0xbf02c3c)-; HASH(0xe5e1198)-; HASH(0xf281cf8)-; HASH(0xf2c9d30)-; HASH(0xf810744)-; HASH(0xf5ba4e8)-; HASH(0xfa5774c)-; HASH(0xc4b43a4)-; HASH(0xdf0e2a4)-; HASH(0xf3ca478)-; HASH(0xf942a28)-; HASH(0xc700248)-; HASH(0xdf0f96c)-; HASH(0xc702aa4)-; HASH(0xf1cae80)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELLAPLTGIVALLFAFYLTNKINRSDPGNPRMQEIAVAIHEGAMAFLMREYRTLIFFVL
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GMTALIVVAGFMTRGAESMQPATAIAYVAGTLCSIGAGYIGMQVATRANVRTANAARHSS
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHCCC
NAALDIAFSGGSVMGMAVVGLGLLGLGIINYVFKNPSIVNGFALGASSIALFARVGGGIY
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCEECHHHHHHHHHHHHHHHCCCCE
TKAADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDVAGMGADLFESYVGSIISGIA
EHHHHHCHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHCCCHHHHHHHHHHHHHHHH
LAAALNIPNGTLVPLMIAAIGIVSSILGAFFVKTGEGANAQKALNTGTMVASILAIVGTF
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LATRLLPAHFTAGSMSYTSTGVFAATIAGLIAGVLIGRITEYYTSGDYEPVKEIAKASQT
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCC
GTATNIIEGLSTGMLSTVLPILVIVIAIIASYRFAGLYGIAMAAVGMLSTTGTTVAVDAY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
GPIADNAGGIAEMAELDPKVRKITDALDSVGNTTAAIGKGFAIGSAALTALALFSAYTAA
CCCCCCCCCHHHHHHCCHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHH
ARITAIDLTDPKVVGGLFIGGMLPFLFAALTMKAVGRAAFQMIEEVRRQFKSIPGLMEGK
HHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
ARPDYARCVAISTGAAIKEMIVPGLLAVLVPLAVGLIPGLGKEALGGLLAGATVTGFLMA
CCCCHHHEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
VMMANAGGAWDNAKKYIEGGQYGGKGSPAHAAAVNGDTVGDPFKDTSGPAMNILIKLMTI
HHHHCCCCCCHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHH
VSLVFAPLFMQL
HHHHHHHHHHCH
>Mature Secondary Structure
MELLAPLTGIVALLFAFYLTNKINRSDPGNPRMQEIAVAIHEGAMAFLMREYRTLIFFVL
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GMTALIVVAGFMTRGAESMQPATAIAYVAGTLCSIGAGYIGMQVATRANVRTANAARHSS
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHCCC
NAALDIAFSGGSVMGMAVVGLGLLGLGIINYVFKNPSIVNGFALGASSIALFARVGGGIY
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCEECHHHHHHHHHHHHHHHCCCCE
TKAADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDVAGMGADLFESYVGSIISGIA
EHHHHHCHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHCCCHHHHHHHHHHHHHHHH
LAAALNIPNGTLVPLMIAAIGIVSSILGAFFVKTGEGANAQKALNTGTMVASILAIVGTF
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LATRLLPAHFTAGSMSYTSTGVFAATIAGLIAGVLIGRITEYYTSGDYEPVKEIAKASQT
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCC
GTATNIIEGLSTGMLSTVLPILVIVIAIIASYRFAGLYGIAMAAVGMLSTTGTTVAVDAY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
GPIADNAGGIAEMAELDPKVRKITDALDSVGNTTAAIGKGFAIGSAALTALALFSAYTAA
CCCCCCCCCHHHHHHCCHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHH
ARITAIDLTDPKVVGGLFIGGMLPFLFAALTMKAVGRAAFQMIEEVRRQFKSIPGLMEGK
HHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
ARPDYARCVAISTGAAIKEMIVPGLLAVLVPLAVGLIPGLGKEALGGLLAGATVTGFLMA
CCCCHHHEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
VMMANAGGAWDNAKKYIEGGQYGGKGSPAHAAAVNGDTVGDPFKDTSGPAMNILIKLMTI
HHHHCCCCCCHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHH
VSLVFAPLFMQL
HHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA