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The map label for this gene is trpC [H]

Identifier: 83590186

GI number: 83590186

Start: 1385226

End: 1386005

Strand: Reverse

Name: trpC [H]

Synonym: Moth_1339

Alternate gene names: 83590186

Gene position: 1386005-1385226 (Counterclockwise)

Preceding gene: 83590187

Following gene: 83590185

Centisome position: 52.72

GC content: 63.21

Gene sequence:

>780_bases
ATGCTGGCGGAGATCCTGGACTACAAACGCCGGGAAGTGGCGGCCGCCAGGGAACAACACCCCCTGGCGGACCTGGAGAA
GGCAGCGGCAGCCATGCCCCTGACCCGGGACTTCGGGGCCGCCCTGCGGCGCCGGGGAAACGAGCTTAAGGTTATAGCTG
AGCTAAAACAGGCTTCTCCCTCCCGGGGCCTTATCAGGGAGGATTTTGACCCTGAAGGTCAGGCCAGGAGTTATATAGCC
GCCGGGGCGGCGGCCATCTCCGTCCTGACGGACCAGAGGTTTTTCCGGGGTCGCCCTGAGTACCTGATCCTGGTGCGCCG
GGTAACCACCCTGCCCCTTCTGCGCAAGGATTTTATCATTGATCCCTACCAGATTTATGAGGCCCGGGCCCTGGGAGCGG
ATGCCATCCTACTGATTGTCGCTGCCCTGGAACCTGCGGAACTGGTGGAATATCTGGACCTGGCCCGGAGGTTAGGCCTG
GCAGCCCTGGTCGAGGTTCATACGGCCCCGGAACTGGAGGTAGCCCTCCGGGCAGGAGCCGGTATTATCGGGATTAACAA
CCGGGACCTGCACACCTTCAAGGTTGACCTGCAAACGACCGGACGCCTGCGATCCATGATTCCCCGGGGACCGGTGGTAG
TGAGCGAGAGTGGCATCCGGAGCCGGGCCGATGCCGCCCTGGTGGCCGGCGCCGGCGTGGATGCCATCTTGGTGGGCGAG
GCCCTGATGACAGCCGGGGACGTTATGGCTAAGATGGCCGAACTACGGCTTGCTATCTAG

Upstream 100 bases:

>100_bases
TCCAGCAAGCCCTGGCCCTGGCCGAATCAAGTATCGATTCCGGCGCCGCGGCGGCAAAACTCCAGGCTATGGTGGCCTGG
GTGGAAAGCTGGGCTGCCTG

Downstream 100 bases:

>100_bases
CTCCGATCATTTTTTGGGTGGAGGAAAAGAATGTGGTCAGAGTAAAAATCTGCGGCATCCGGGATTGGGAAGAAGCCCGG
ATGGTTCTCGACGCGGGCGT

Product: indole-3-glycerol phosphate synthase

Products: NA

Alternate protein names: IGPS [H]

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MLAEILDYKRREVAAAREQHPLADLEKAAAAMPLTRDFGAALRRRGNELKVIAELKQASPSRGLIREDFDPEGQARSYIA
AGAAAISVLTDQRFFRGRPEYLILVRRVTTLPLLRKDFIIDPYQIYEARALGADAILLIVAALEPAELVEYLDLARRLGL
AALVEVHTAPELEVALRAGAGIIGINNRDLHTFKVDLQTTGRLRSMIPRGPVVVSESGIRSRADAALVAGAGVDAILVGE
ALMTAGDVMAKMAELRLAI

Sequences:

>Translated_259_residues
MLAEILDYKRREVAAAREQHPLADLEKAAAAMPLTRDFGAALRRRGNELKVIAELKQASPSRGLIREDFDPEGQARSYIA
AGAAAISVLTDQRFFRGRPEYLILVRRVTTLPLLRKDFIIDPYQIYEARALGADAILLIVAALEPAELVEYLDLARRLGL
AALVEVHTAPELEVALRAGAGIIGINNRDLHTFKVDLQTTGRLRSMIPRGPVVVSESGIRSRADAALVAGAGVDAILVGE
ALMTAGDVMAKMAELRLAI
>Mature_259_residues
MLAEILDYKRREVAAAREQHPLADLEKAAAAMPLTRDFGAALRRRGNELKVIAELKQASPSRGLIREDFDPEGQARSYIA
AGAAAISVLTDQRFFRGRPEYLILVRRVTTLPLLRKDFIIDPYQIYEARALGADAILLIVAALEPAELVEYLDLARRLGL
AALVEVHTAPELEVALRAGAGIIGINNRDLHTFKVDLQTTGRLRSMIPRGPVVVSESGIRSRADAALVAGAGVDAILVGE
ALMTAGDVMAKMAELRLAI

Specific function: Bifunctional Enzyme That Catalyzes Two Sequential Steps Of Tryptophan Biosynthetic Pathway. The First Reaction Is Catalyzed By The Isomerase, Coded By The Trpf Domain; The Second Reaction Is Catalyzed By The Synthase, Coded By The Trpc Domain. [C]

COG id: COG0134

COG function: function code E; Indole-3-glycerol phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpC family [H]

Homologues:

Organism=Escherichia coli, GI87081863, Length=250, Percent_Identity=40.4, Blast_Score=160, Evalue=8e-41,
Organism=Saccharomyces cerevisiae, GI6322638, Length=231, Percent_Identity=42.8571428571429, Blast_Score=164, Evalue=9e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR013798
- InterPro:   IPR001468
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00218 IGPS [H]

EC number: =4.1.1.48 [H]

Molecular weight: Translated: 28095; Mature: 28095

Theoretical pI: Translated: 7.76; Mature: 7.76

Prosite motif: PS00614 IGPS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAEILDYKRREVAAAREQHPLADLEKAAAAMPLTRDFGAALRRRGNELKVIAELKQASP
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHCCC
SRGLIREDFDPEGQARSYIAAGAAAISVLTDQRFFRGRPEYLILVRRVTTLPLLRKDFII
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHCC
DPYQIYEARALGADAILLIVAALEPAELVEYLDLARRLGLAALVEVHTAPELEVALRAGA
CHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCC
GIIGINNRDLHTFKVDLQTTGRLRSMIPRGPVVVSESGIRSRADAALVAGAGVDAILVGE
CEEECCCCCEEEEEEEECHHHHHHHHCCCCCEEEECCCCCCCCCHHEEECCCCCHHHHHH
ALMTAGDVMAKMAELRLAI
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLAEILDYKRREVAAAREQHPLADLEKAAAAMPLTRDFGAALRRRGNELKVIAELKQASP
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHCCC
SRGLIREDFDPEGQARSYIAAGAAAISVLTDQRFFRGRPEYLILVRRVTTLPLLRKDFII
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHCC
DPYQIYEARALGADAILLIVAALEPAELVEYLDLARRLGLAALVEVHTAPELEVALRAGA
CHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCC
GIIGINNRDLHTFKVDLQTTGRLRSMIPRGPVVVSESGIRSRADAALVAGAGVDAILVGE
CEEECCCCCEEEEEEEECHHHHHHHHCCCCCEEEECCCCCCCCCHHEEECCCCCHHHHHH
ALMTAGDVMAKMAELRLAI
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA