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The map label for this gene is trpD

Identifier: 83590187

GI number: 83590187

Start: 1386005

End: 1387024

Strand: Reverse

Name: trpD

Synonym: Moth_1340

Alternate gene names: 83590187

Gene position: 1387024-1386005 (Counterclockwise)

Preceding gene: 83590188

Following gene: 83590186

Centisome position: 52.76

GC content: 63.24

Gene sequence:

>1020_bases
GTGTTGAAAGCCCAGATTAGCAAAGTAGTAGCCGGCCAGCACTTGAGCGAAGCCGAGGCCGCAGAAGCCATGGACATAAT
CATGGCGGGCGAAGCCACCCCGGCCCAGATTGCCGCTTTCCTCACCGCCCTGCGCCTTAAAGGGGAAATGGTAGACGAGA
TAACCGGTTTTGCCCGCAGCATGCGCCGCCGGGCTATTCCCCTTACCACTAGCCACCCGGTATTTGTGGACACCTGTGGT
ACCGGGGGAGACGGCCGCCAAACCTTTAACATTTCCACCACCGCGGCCTTCGTCGTGGCCGGCGCCGGGGTAGCAGTAGC
CAAACACGGCAACCGTTCAGTTTCCAGCCGTTGCGGTAGCGCCGACATGCTGGAAGCCCTGGGGATCAAAGTCGACCTGC
CTCCGGACGCCGTTGCCCGCTGCCTGGATGAAGTGGGCATGGCCTTCCTCTTTGCTCCCGTTTTTCATGGTGCAATGAAA
TACGCCGCCGGACCGCGGCGGGAGATCGGCATTCGTACAGCCTTCAACCTCCTGGGGCCCCTGACTAACCCGGCGGGCGC
TCCCTGCCAGCTGGTGGGAGTTTACGACCCGGATTTAACGGAAACAGTCGCGGCCGTCCTGGGGCGCCTGGGCAGCCGCC
GGGCCTATGTAGTCCACGGTAGCGATGGACTGGACGAAGTAACTATCACCGGACCCAGCAAGATAACCTGCCTCGATAAA
GGCGCGATCAGGACGTATACCTTTACCCCGGAAGATGTCGGCCTGCCACGGGCGAACCTTGCCGACCTGGCCGGGGGTAC
AGCCACCGACAATGCCGCCATTGCCCGCGCCGTCCTTTCCGGTACCAGGGGCCCGGCCCGGGACGTCGTCCTCATTAATG
CCGCCTTCGCCCTCCTGGCAGCCGGTGCCGCTGACACCCTCCAGCAAGCCCTGGCCCTGGCCGAATCAAGTATCGATTCC
GGCGCCGCGGCGGCAAAACTCCAGGCTATGGTGGCCTGGGTGGAAAGCTGGGCTGCCTGA

Upstream 100 bases:

>100_bases
GAATTTTTTGGCCATTGGCCCCTTCGCGAGGACCAGAAGTAAAGAAAATGGAGTCAGCCTGGATAAATAATTACTGTATT
TTTGAGAGGAGTTGAGCTTA

Downstream 100 bases:

>100_bases
TGCTGGCGGAGATCCTGGACTACAAACGCCGGGAAGTGGCGGCCGCCAGGGAACAACACCCCCTGGCGGACCTGGAGAAG
GCAGCGGCAGCCATGCCCCT

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MLKAQISKVVAGQHLSEAEAAEAMDIIMAGEATPAQIAAFLTALRLKGEMVDEITGFARSMRRRAIPLTTSHPVFVDTCG
TGGDGRQTFNISTTAAFVVAGAGVAVAKHGNRSVSSRCGSADMLEALGIKVDLPPDAVARCLDEVGMAFLFAPVFHGAMK
YAAGPRREIGIRTAFNLLGPLTNPAGAPCQLVGVYDPDLTETVAAVLGRLGSRRAYVVHGSDGLDEVTITGPSKITCLDK
GAIRTYTFTPEDVGLPRANLADLAGGTATDNAAIARAVLSGTRGPARDVVLINAAFALLAAGAADTLQQALALAESSIDS
GAAAAKLQAMVAWVESWAA

Sequences:

>Translated_339_residues
MLKAQISKVVAGQHLSEAEAAEAMDIIMAGEATPAQIAAFLTALRLKGEMVDEITGFARSMRRRAIPLTTSHPVFVDTCG
TGGDGRQTFNISTTAAFVVAGAGVAVAKHGNRSVSSRCGSADMLEALGIKVDLPPDAVARCLDEVGMAFLFAPVFHGAMK
YAAGPRREIGIRTAFNLLGPLTNPAGAPCQLVGVYDPDLTETVAAVLGRLGSRRAYVVHGSDGLDEVTITGPSKITCLDK
GAIRTYTFTPEDVGLPRANLADLAGGTATDNAAIARAVLSGTRGPARDVVLINAAFALLAAGAADTLQQALALAESSIDS
GAAAAKLQAMVAWVESWAA
>Mature_339_residues
MLKAQISKVVAGQHLSEAEAAEAMDIIMAGEATPAQIAAFLTALRLKGEMVDEITGFARSMRRRAIPLTTSHPVFVDTCG
TGGDGRQTFNISTTAAFVVAGAGVAVAKHGNRSVSSRCGSADMLEALGIKVDLPPDAVARCLDEVGMAFLFAPVFHGAMK
YAAGPRREIGIRTAFNLLGPLTNPAGAPCQLVGVYDPDLTETVAAVLGRLGSRRAYVVHGSDGLDEVTITGPSKITCLDK
GAIRTYTFTPEDVGLPRANLADLAGGTATDNAAIARAVLSGTRGPARDVVLINAAFALLAAGAADTLQQALALAESSIDS
GAAAAKLQAMVAWVESWAA

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=280, Percent_Identity=43.2142857142857, Blast_Score=220, Evalue=1e-58,
Organism=Escherichia coli, GI1787019, Length=290, Percent_Identity=25.5172413793103, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320561, Length=334, Percent_Identity=32.0359281437126, Blast_Score=140, Evalue=2e-34,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_MOOTA (Q2RIT6)

Other databases:

- EMBL:   CP000232
- RefSeq:   YP_430196.1
- HSSP:   P50384
- ProteinModelPortal:   Q2RIT6
- SMR:   Q2RIT6
- STRING:   Q2RIT6
- GeneID:   3831897
- GenomeReviews:   CP000232_GR
- KEGG:   mta:Moth_1340
- NMPDR:   fig|264732.9.peg.1335
- eggNOG:   COG0547
- HOGENOM:   HBG559996
- OMA:   LGVYSPE
- PhylomeDB:   Q2RIT6
- BioCyc:   MTHE264732:MOTH_1340-MONOMER
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 34859; Mature: 34859

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKAQISKVVAGQHLSEAEAAEAMDIIMAGEATPAQIAAFLTALRLKGEMVDEITGFARS
CCHHHHHHHHHCCCCHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MRRRAIPLTTSHPVFVDTCGTGGDGRQTFNISTTAAFVVAGAGVAVAKHGNRSVSSRCGS
HHHCCCCCCCCCCEEEEECCCCCCCCEEEEECHHHHHHHCCCCEEEEECCCCHHHHHCCC
ADMLEALGIKVDLPPDAVARCLDEVGMAFLFAPVFHGAMKYAAGPRREIGIRTAFNLLGP
HHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
LTNPAGAPCQLVGVYDPDLTETVAAVLGRLGSRRAYVVHGSDGLDEVTITGPSKITCLDK
CCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEECCCEEEEECC
GAIRTYTFTPEDVGLPRANLADLAGGTATDNAAIARAVLSGTRGPARDVVLINAAFALLA
CCEEEEEECCHHCCCCCCCHHHHCCCCCCCHHHHHHHHHHCCCCCCCCEEEHHHHHHHHH
AGAADTLQQALALAESSIDSGAAAAKLQAMVAWVESWAA
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLKAQISKVVAGQHLSEAEAAEAMDIIMAGEATPAQIAAFLTALRLKGEMVDEITGFARS
CCHHHHHHHHHCCCCHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MRRRAIPLTTSHPVFVDTCGTGGDGRQTFNISTTAAFVVAGAGVAVAKHGNRSVSSRCGS
HHHCCCCCCCCCCEEEEECCCCCCCCEEEEECHHHHHHHCCCCEEEEECCCCHHHHHCCC
ADMLEALGIKVDLPPDAVARCLDEVGMAFLFAPVFHGAMKYAAGPRREIGIRTAFNLLGP
HHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
LTNPAGAPCQLVGVYDPDLTETVAAVLGRLGSRRAYVVHGSDGLDEVTITGPSKITCLDK
CCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEECCCEEEEECC
GAIRTYTFTPEDVGLPRANLADLAGGTATDNAAIARAVLSGTRGPARDVVLINAAFALLA
CCEEEEEECCHHCCCCCCCHHHHCCCCCCCHHHHHHHHHHCCCCCCCCEEEHHHHHHHHH
AGAADTLQQALALAESSIDSGAAAAKLQAMVAWVESWAA
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA