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The map label for this gene is glnA [H]

Identifier: 83590145

GI number: 83590145

Start: 1337893

End: 1339224

Strand: Reverse

Name: glnA [H]

Synonym: Moth_1297

Alternate gene names: 83590145

Gene position: 1339224-1337893 (Counterclockwise)

Preceding gene: 83590150

Following gene: 83590143

Centisome position: 50.94

GC content: 55.93

Gene sequence:

>1332_bases
ATGAATGAACAACTGACCAAAGAAGACGTCCTGCAGATGGTTGAAGAAATGAACGTCCGTTTTATCCGGCTCCAGTTTAC
CGATATCTTCGGGGTATTAAAAAATGTGGCCATAACCCCGGCCGAGCTAGAGAAAGCCCTTGACGGCGAATTAATGTTCG
ATGGCTCTTCCATCCACGGTTTCGTCCGCATCGAAGAATCCGACATGTACCTGCGGCCTGACCCGACCACCTTCGCCATT
TTCCCCTGGCGGCCCATGGACGGGGCCGTAGCCAGGTTGATCTGTGACGTCTATAACCCGGACGGCACCCCCTTTGCCGG
CTGTCCCCGGGGGGTTTTAAAGCGCGTCCTGGCTGAAGCCGAAGCTATGGGCTATACCATGTACGCCGGCCCGGAAGCGG
AGTTTTTCCTTTTCCATACCGACGGGCAAAAACCGACCCTCGTAACCCACGACCAGGCCGGCTATTTCGACCTTTCCCCA
GTCGACCTGGGTGAAGACGCGCGCCGGGATATGGTCCTTTCCCTGGAAGCCATGGGTTTCGAGGTTGAGGCTTCCCATCA
CGAGGTGGCCCCGGGCCAGCACGAAATAGACTTTAAGTATGATAACGCCCTGGCCACGGCCGATAAGATTGCCACCTTTA
AATTTGTCGTCCGGACCATCGCCCAGCGCCACGGTCTCCATGCCACCTTTATGCCCAAGCCTGTGGCTGGCATCAACGGT
TCCGGCATGCATACCCACCAATCCTTATTTAAAGAAGGCCAGAATGCCTTCTATGATCCGGACGACCCCCTGCAATTAAG
CAAGGTAGCCTATTACTATATTGGCGGCCTGATGCACCACGCCCGGGCCCTGGCGGCCATCACCAATCCGACAGTCAATT
CTTATAAACGCCTGGTACCAGGTTTTGAGGCCCCGGTCTATATCGCCTGGTCCCCCCGCAATCGCAGCCCCTTGATACGC
GTGCCGGCCAAGCGCGGGGCCTCAACTAGAATAGAATTACGCAACCCCGACCCGTCCTGTAACCCTTACCTGGCCCTGGC
CGTTATGTTGAAAGCCGGTTTGGACGGGATCAAGAAACAGATTCAGCCCCCGGCTCCGACAGAACGCAATATCTATGAGA
TGACGCCTGCCGAACGCCGTGACCTGGGCATCGGCAGCCTGCCGGGTGATTTAAAAGATGCCTTAGCGGAACTCTCCCGC
GACGAAGTGATCCGGGAGGCCCTGGGGGATCACATTTACCAGCATTTTGTCGAGGCCAAGGAGAAGGAATGGGAACAGTA
TCGTATCCAGGTCCACCAGTGGGAAATAGACCACTACCTTACACTGTTTTAA

Upstream 100 bases:

>100_bases
GGAGCAACGTGGTTCCCAGGGAAGAGGCAAAGAAGCCCGTAGCGGCTACACCCAGTGTAAGCCGCGGCGGGCTTTATCTT
TTTTACTGAGGAGAGGCACA

Downstream 100 bases:

>100_bases
ACCTTTAGCTGGCTTCCTCCAACACGCCAGGAAATTCGGCGGCGTAGTTCAAGATGCGCTGCAGGATTTCCTGGCGTTTG
GCATTTATGGCCTCAAAATT

Product: L-glutamine synthetase

Products: NA

Alternate protein names: Glutamate--ammonia ligase [H]

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MNEQLTKEDVLQMVEEMNVRFIRLQFTDIFGVLKNVAITPAELEKALDGELMFDGSSIHGFVRIEESDMYLRPDPTTFAI
FPWRPMDGAVARLICDVYNPDGTPFAGCPRGVLKRVLAEAEAMGYTMYAGPEAEFFLFHTDGQKPTLVTHDQAGYFDLSP
VDLGEDARRDMVLSLEAMGFEVEASHHEVAPGQHEIDFKYDNALATADKIATFKFVVRTIAQRHGLHATFMPKPVAGING
SGMHTHQSLFKEGQNAFYDPDDPLQLSKVAYYYIGGLMHHARALAAITNPTVNSYKRLVPGFEAPVYIAWSPRNRSPLIR
VPAKRGASTRIELRNPDPSCNPYLALAVMLKAGLDGIKKQIQPPAPTERNIYEMTPAERRDLGIGSLPGDLKDALAELSR
DEVIREALGDHIYQHFVEAKEKEWEQYRIQVHQWEIDHYLTLF

Sequences:

>Translated_443_residues
MNEQLTKEDVLQMVEEMNVRFIRLQFTDIFGVLKNVAITPAELEKALDGELMFDGSSIHGFVRIEESDMYLRPDPTTFAI
FPWRPMDGAVARLICDVYNPDGTPFAGCPRGVLKRVLAEAEAMGYTMYAGPEAEFFLFHTDGQKPTLVTHDQAGYFDLSP
VDLGEDARRDMVLSLEAMGFEVEASHHEVAPGQHEIDFKYDNALATADKIATFKFVVRTIAQRHGLHATFMPKPVAGING
SGMHTHQSLFKEGQNAFYDPDDPLQLSKVAYYYIGGLMHHARALAAITNPTVNSYKRLVPGFEAPVYIAWSPRNRSPLIR
VPAKRGASTRIELRNPDPSCNPYLALAVMLKAGLDGIKKQIQPPAPTERNIYEMTPAERRDLGIGSLPGDLKDALAELSR
DEVIREALGDHIYQHFVEAKEKEWEQYRIQVHQWEIDHYLTLF
>Mature_443_residues
MNEQLTKEDVLQMVEEMNVRFIRLQFTDIFGVLKNVAITPAELEKALDGELMFDGSSIHGFVRIEESDMYLRPDPTTFAI
FPWRPMDGAVARLICDVYNPDGTPFAGCPRGVLKRVLAEAEAMGYTMYAGPEAEFFLFHTDGQKPTLVTHDQAGYFDLSP
VDLGEDARRDMVLSLEAMGFEVEASHHEVAPGQHEIDFKYDNALATADKIATFKFVVRTIAQRHGLHATFMPKPVAGING
SGMHTHQSLFKEGQNAFYDPDDPLQLSKVAYYYIGGLMHHARALAAITNPTVNSYKRLVPGFEAPVYIAWSPRNRSPLIR
VPAKRGASTRIELRNPDPSCNPYLALAVMLKAGLDGIKKQIQPPAPTERNIYEMTPAERRDLGIGSLPGDLKDALAELSR
DEVIREALGDHIYQHFVEAKEKEWEQYRIQVHQWEIDHYLTLF

Specific function: Unknown

COG id: COG0174

COG function: function code E; Glutamine synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Homo sapiens, GI221307485, Length=452, Percent_Identity=26.5486725663717, Blast_Score=146, Evalue=5e-35,
Organism=Escherichia coli, GI1790301, Length=479, Percent_Identity=39.6659707724426, Blast_Score=301, Evalue=6e-83,
Organism=Escherichia coli, GI87081870, Length=458, Percent_Identity=27.292576419214, Blast_Score=130, Evalue=1e-31,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 15324 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal medi

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146
- InterPro:   IPR004809 [H]

Pfam domain/function: PF00120 Gln-synt_C; PF03951 Gln-synt_N [H]

EC number: =6.3.1.2 [H]

Molecular weight: Translated: 49878; Mature: 49878

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS00180 GLNA_1 ; PS00181 GLNA_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEQLTKEDVLQMVEEMNVRFIRLQFTDIFGVLKNVAITPAELEKALDGELMFDGSSIHG
CCCCCCHHHHHHHHHHCCEEEEEEEHHHHHHHHHHCCCCHHHHHHHCCCCEEEECCCEEE
FVRIEESDMYLRPDPTTFAIFPWRPMDGAVARLICDVYNPDGTPFAGCPRGVLKRVLAEA
EEEEECCCEEECCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
EAMGYTMYAGPEAEFFLFHTDGQKPTLVTHDQAGYFDLSPVDLGEDARRDMVLSLEAMGF
HHCCEEEEECCCCEEEEEECCCCCCEEEEECCCCEEECCCCCCCCHHHHCEEEEEECCCE
EVEASHHEVAPGQHEIDFKYDNALATADKIATFKFVVRTIAQRHGLHATFMPKPVAGING
EEECCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCC
SGMHTHQSLFKEGQNAFYDPDDPLQLSKVAYYYIGGLMHHARALAAITNPTVNSYKRLVP
CCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCC
GFEAPVYIAWSPRNRSPLIRVPAKRGASTRIELRNPDPSCNPYLALAVMLKAGLDGIKKQ
CCCCCEEEEECCCCCCCEEECCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCHHHHHHH
IQPPAPTERNIYEMTPAERRDLGIGSLPGDLKDALAELSRDEVIREALGDHIYQHFVEAK
CCCCCCCCCCEEECCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKEWEQYRIQVHQWEIDHYLTLF
HHHHHHHEEEEEEEEECEEEEEC
>Mature Secondary Structure
MNEQLTKEDVLQMVEEMNVRFIRLQFTDIFGVLKNVAITPAELEKALDGELMFDGSSIHG
CCCCCCHHHHHHHHHHCCEEEEEEEHHHHHHHHHHCCCCHHHHHHHCCCCEEEECCCEEE
FVRIEESDMYLRPDPTTFAIFPWRPMDGAVARLICDVYNPDGTPFAGCPRGVLKRVLAEA
EEEEECCCEEECCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
EAMGYTMYAGPEAEFFLFHTDGQKPTLVTHDQAGYFDLSPVDLGEDARRDMVLSLEAMGF
HHCCEEEEECCCCEEEEEECCCCCCEEEEECCCCEEECCCCCCCCHHHHCEEEEEECCCE
EVEASHHEVAPGQHEIDFKYDNALATADKIATFKFVVRTIAQRHGLHATFMPKPVAGING
EEECCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCC
SGMHTHQSLFKEGQNAFYDPDDPLQLSKVAYYYIGGLMHHARALAAITNPTVNSYKRLVP
CCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCC
GFEAPVYIAWSPRNRSPLIRVPAKRGASTRIELRNPDPSCNPYLALAVMLKAGLDGIKKQ
CCCCCEEEEECCCCCCCEEECCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCHHHHHHH
IQPPAPTERNIYEMTPAERRDLGIGSLPGDLKDALAELSRDEVIREALGDHIYQHFVEAK
CCCCCCCCCCEEECCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKEWEQYRIQVHQWEIDHYLTLF
HHHHHHHEEEEEEEEECEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2891680; 1981087 [H]