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The map label for this gene is yqeC [H]

Identifier: 83590131

GI number: 83590131

Start: 1323924

End: 1324820

Strand: Reverse

Name: yqeC [H]

Synonym: Moth_1283

Alternate gene names: 83590131

Gene position: 1324820-1323924 (Counterclockwise)

Preceding gene: 83590132

Following gene: 83590130

Centisome position: 50.4

GC content: 57.19

Gene sequence:

>897_bases
TTGCATATCGGCTTAGTCGGTCTTGGTCGAATGGGCCTCAACCTGGCCCTCAATATGCTGGATCATGGTCATGAAGTGCG
AGGATACGCCCGCACTAAGGCTACCGTGGACAAAGCCGCGGCGCAAGGAATTAAAGGCGCTTATAGTTTAGAAGAACTAG
CAGGCCAGCTAAAGACCCCGCGCCTGGTCTGGCTGATGATCCCGGCTGGCAAAGCCGTGGACGAAGTTATTGAGCAATTA
GCCCCTTTGCTTGCTCCCGGGGATATTATCGTCGACGGGGGTAACTCTCACTACCGGGACACCTTGCGCCGTTATAAATT
TTTAAAGGAAAAGGGCATCCACCTTGTCGATTCCGGCACCAGCGGCGGTGTAGAGGGTGCTCGCCACGGTGCCTGCTGCA
TGGTCGGAGCCGAGGACGAGGTTTTCGCTTACCTGGAACCTTTATTTAAAGATATCACCGTACCCGGAGGTTATCTCCAT
ACCGGGCCGCCCGGCAGCGGCCATTATGTAAAAATGGTCCATAACGGCATTGAATACGGTATGATGCAGGCCATCGGCGA
GGGCATGGAAGTCCTGGCCGGCGCACCCTTCAAGCTGGACTTGAAGGAAGTGGCCCGGGTCTGGCGCCACGGGTCGGTCA
TCCGCGGCTGGCTCATGGACCTGATGGAAAAAGCCCTGGCTAAAGATAATACCCTGGATGGCATCAAGGATATCGCCTAT
TCTTCGGGCGAAGGCCTGTGGACGATAGAAGAAGCCCTGCGGCTTAAGGTACCGGCGCCGGTAATCACGGCAGCCCTGCT
GATGCGTTACCGCTCTGAGCAGGAGGAGAGCTTTGCTACCAAGGTGGTCGCCGCCCTGCGCCACGAGTTCGGGGGCCACG
ACGTGGCCCGGAAATAG

Upstream 100 bases:

>100_bases
AGGAGGATTATAAGGCCGGCAAAATATAAGGATACTAATGCTAAAAGTATAGTACTGGACAATATAAGAAACATTTCACA
TGCAGGGGATGAATATTAGA

Downstream 100 bases:

>100_bases
GAGGTTAAGCGACCTGACGTGGTACCAGGCTGCTTGTTTCATAAGGCAGACAGGCCCATCAACTTTATCCGACATCGACT
GCGAATTTTAGTTGACATTA

Product: 6-phosphogluconate dehydrogenase-like protein

Products: D-ribulose 5-phosphate; CO2; NADPH

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MHIGLVGLGRMGLNLALNMLDHGHEVRGYARTKATVDKAAAQGIKGAYSLEELAGQLKTPRLVWLMIPAGKAVDEVIEQL
APLLAPGDIIVDGGNSHYRDTLRRYKFLKEKGIHLVDSGTSGGVEGARHGACCMVGAEDEVFAYLEPLFKDITVPGGYLH
TGPPGSGHYVKMVHNGIEYGMMQAIGEGMEVLAGAPFKLDLKEVARVWRHGSVIRGWLMDLMEKALAKDNTLDGIKDIAY
SSGEGLWTIEEALRLKVPAPVITAALLMRYRSEQEESFATKVVAALRHEFGGHDVARK

Sequences:

>Translated_298_residues
MHIGLVGLGRMGLNLALNMLDHGHEVRGYARTKATVDKAAAQGIKGAYSLEELAGQLKTPRLVWLMIPAGKAVDEVIEQL
APLLAPGDIIVDGGNSHYRDTLRRYKFLKEKGIHLVDSGTSGGVEGARHGACCMVGAEDEVFAYLEPLFKDITVPGGYLH
TGPPGSGHYVKMVHNGIEYGMMQAIGEGMEVLAGAPFKLDLKEVARVWRHGSVIRGWLMDLMEKALAKDNTLDGIKDIAY
SSGEGLWTIEEALRLKVPAPVITAALLMRYRSEQEESFATKVVAALRHEFGGHDVARK
>Mature_298_residues
MHIGLVGLGRMGLNLALNMLDHGHEVRGYARTKATVDKAAAQGIKGAYSLEELAGQLKTPRLVWLMIPAGKAVDEVIEQL
APLLAPGDIIVDGGNSHYRDTLRRYKFLKEKGIHLVDSGTSGGVEGARHGACCMVGAEDEVFAYLEPLFKDITVPGGYLH
TGPPGSGHYVKMVHNGIEYGMMQAIGEGMEVLAGAPFKLDLKEVARVWRHGSVIRGWLMDLMEKALAKDNTLDGIKDIAY
SSGEGLWTIEEALRLKVPAPVITAALLMRYRSEQEESFATKVVAALRHEFGGHDVARK

Specific function: May act as NAD-dependent 6-P-gluconate dehydrogenase [H]

COG id: COG1023

COG function: function code G; Predicted 6-phosphogluconate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 6-phosphogluconate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI40068518, Length=294, Percent_Identity=40.8163265306122, Blast_Score=171, Evalue=5e-43,
Organism=Escherichia coli, GI1788341, Length=303, Percent_Identity=35.3135313531353, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI1786719, Length=198, Percent_Identity=28.7878787878788, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17542558, Length=287, Percent_Identity=39.3728222996516, Blast_Score=172, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6321695, Length=300, Percent_Identity=41.3333333333333, Blast_Score=197, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6321977, Length=299, Percent_Identity=41.1371237458194, Blast_Score=184, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24639279, Length=283, Percent_Identity=39.9293286219081, Blast_Score=161, Evalue=4e-40,
Organism=Drosophila melanogaster, GI24655230, Length=196, Percent_Identity=30.1020408163265, Blast_Score=68, Evalue=9e-12,
Organism=Drosophila melanogaster, GI19922568, Length=196, Percent_Identity=30.1020408163265, Blast_Score=68, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR004849
- InterPro:   IPR006114
- InterPro:   IPR006115
- InterPro:   IPR006184
- InterPro:   IPR013328
- InterPro:   IPR016040
- InterPro:   IPR006183 [H]

Pfam domain/function: PF00393 6PGD; PF03446 NAD_binding_2 [H]

EC number: 1.1.1.44

Molecular weight: Translated: 32366; Mature: 32366

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHIGLVGLGRMGLNLALNMLDHGHEVRGYARTKATVDKAAAQGIKGAYSLEELAGQLKTP
CEEEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCC
RLVWLMIPAGKAVDEVIEQLAPLLAPGDIIVDGGNSHYRDTLRRYKFLKEKGIHLVDSGT
EEEEEEECCCHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHCCCEEEECCC
SGGVEGARHGACCMVGAEDEVFAYLEPLFKDITVPGGYLHTGPPGSGHYVKMVHNGIEYG
CCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCEEHHHHCCHHHH
MMQAIGEGMEVLAGAPFKLDLKEVARVWRHGSVIRGWLMDLMEKALAKDNTLDGIKDIAY
HHHHHHHHHHHHCCCCCEECHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
SSGEGLWTIEEALRLKVPAPVITAALLMRYRSEQEESFATKVVAALRHEFGGHDVARK
CCCCCEEEHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MHIGLVGLGRMGLNLALNMLDHGHEVRGYARTKATVDKAAAQGIKGAYSLEELAGQLKTP
CEEEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCC
RLVWLMIPAGKAVDEVIEQLAPLLAPGDIIVDGGNSHYRDTLRRYKFLKEKGIHLVDSGT
EEEEEEECCCHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHCCCEEEECCC
SGGVEGARHGACCMVGAEDEVFAYLEPLFKDITVPGGYLHTGPPGSGHYVKMVHNGIEYG
CCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCEEHHHHCCHHHH
MMQAIGEGMEVLAGAPFKLDLKEVARVWRHGSVIRGWLMDLMEKALAKDNTLDGIKDIAY
HHHHHHHHHHHHCCCCCEECHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
SSGEGLWTIEEALRLKVPAPVITAALLMRYRSEQEESFATKVVAALRHEFGGHDVARK
CCCCCEEEHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.05 {6-phosphogluconate}} 0.01 {6-phosphogluconate}} [C]

Substrates: 6-phospho-D-gluconate; NADP+

Specific reaction: 6-phospho-D-gluconate + NADP+ = D-ribulose 5-phosphate + CO2 + NADPH

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]