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The map label for this gene is speH

Identifier: 83590130

GI number: 83590130

Start: 1323375

End: 1323752

Strand: Reverse

Name: speH

Synonym: Moth_1282

Alternate gene names: 83590130

Gene position: 1323752-1323375 (Counterclockwise)

Preceding gene: 83590131

Following gene: 83590129

Centisome position: 50.36

GC content: 53.97

Gene sequence:

>378_bases
TTGCGCGCATTGGGCCGTCATGTTTTAGCTGAGGTTTATGGATGCAGCTTCGAGATCCTGAATGACATTAAAAAGGTTGA
AGAAATCATGGTCAAAGCCGCCCTCGAAGCCGGTGCCGAAATCCGCGAAGTCTGCTTCCATAAATTCAGCCCTCAGGGTG
TCAGCGGCGTGGTGGTCATCTCTGAATCGCACCTGGCAATCCATACGTGGCCGGAGTTAGGGTATGCTGCCGTAGATGTT
TTTACCTGTGGGGAGCGGGTAAACCCCTGGGATGCCTGCCGTTACTTAACGGAGAAATTCAAGGCAGCTGATGTCCACGC
CACCGAGATCGAGCGGGGCGTTATAGAACCTCCACAGGCGGCGGCGGTAAATCTGTAG

Upstream 100 bases:

>100_bases
ACATCGACTGCGAATTTTAGTTGACATTAAGGGGCGGGGCGGTTACAATTGGATTTGATTGAAGTCTTGCCAGACTTTTA
TCTTGGAGGAGGAATGATAA

Downstream 100 bases:

>100_bases
GAGGGATATTTATTTTATTACCTACAACTAAAGGTAATGGCTAACAGGCCTTGCATGGGGAAAACGTGCAGGGCCTGTGG
CATTTTTAAGCCTTTATCTA

Product: S-adenosylmethionine decarboxylase proenzyme

Products: NA

Alternate protein names: AdoMetDC; SAMDC

Number of amino acids: Translated: 125; Mature: 125

Protein sequence:

>125_residues
MRALGRHVLAEVYGCSFEILNDIKKVEEIMVKAALEAGAEIREVCFHKFSPQGVSGVVVISESHLAIHTWPELGYAAVDV
FTCGERVNPWDACRYLTEKFKAADVHATEIERGVIEPPQAAAVNL

Sequences:

>Translated_125_residues
MRALGRHVLAEVYGCSFEILNDIKKVEEIMVKAALEAGAEIREVCFHKFSPQGVSGVVVISESHLAIHTWPELGYAAVDV
FTCGERVNPWDACRYLTEKFKAADVHATEIERGVIEPPQAAAVNL
>Mature_125_residues
MRALGRHVLAEVYGCSFEILNDIKKVEEIMVKAALEAGAEIREVCFHKFSPQGVSGVVVISESHLAIHTWPELGYAAVDV
FTCGERVNPWDACRYLTEKFKAADVHATEIERGVIEPPQAAAVNL

Specific function: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine

COG id: COG1586

COG function: function code E; S-adenosylmethionine decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SPEH_MOOTA (Q2RIZ3)

Other databases:

- EMBL:   CP000232
- RefSeq:   YP_430139.1
- ProteinModelPortal:   Q2RIZ3
- SMR:   Q2RIZ3
- STRING:   Q2RIZ3
- GeneID:   3832922
- GenomeReviews:   CP000232_GR
- KEGG:   mta:Moth_1282
- NMPDR:   fig|264732.9.peg.1274
- eggNOG:   COG1586
- HOGENOM:   HBG485559
- OMA:   RTHKFSP
- ProtClustDB:   PRK03124
- BioCyc:   MTHE264732:MOTH_1282-MONOMER
- HAMAP:   MF_00464
- InterPro:   IPR003826
- InterPro:   IPR016067
- InterPro:   IPR017716
- Gene3D:   G3DSA:3.60.90.10
- TIGRFAMs:   TIGR03330

Pfam domain/function: PF02675 AdoMet_dc; SSF56276 S-AdenosylMet_decarbase_core

EC number: =4.1.1.50

Molecular weight: Translated: 13766; Mature: 13766

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: ACT_SITE 63-63 ACT_SITE 68-68 ACT_SITE 83-83

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRALGRHVLAEVYGCSFEILNDIKKVEEIMVKAALEAGAEIREVCFHKFSPQGVSGVVVI
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEEE
SESHLAIHTWPELGYAAVDVFTCGERVNPWDACRYLTEKFKAADVHATEIERGVIEPPQA
ECCCEEEEECCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCC
AAVNL
CCCCC
>Mature Secondary Structure
MRALGRHVLAEVYGCSFEILNDIKKVEEIMVKAALEAGAEIREVCFHKFSPQGVSGVVVI
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEEE
SESHLAIHTWPELGYAAVDVFTCGERVNPWDACRYLTEKFKAADVHATEIERGVIEPPQA
ECCCEEEEECCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCC
AAVNL
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA