Click here to switch to the map view.

The map label for this gene is siaT [H]

Identifier: 83595005

GI number: 83595005

Start: 4223390

End: 4224673

Strand: Reverse

Name: siaT [H]

Synonym: Rru_A3676

Alternate gene names: 83595005

Gene position: 4224673-4223390 (Counterclockwise)

Preceding gene: 83595006

Following gene: 83595004

Centisome position: 97.06

GC content: 63.32

Gene sequence:

>1284_bases
ATGAGCGCCCTCATCATCTTCACCCTGCTGCTCTGCCTGATGCTGACGGGCATGCCGATCTCGATCTCGCTCGGCCTGAC
GGTTCTGACCTTCCTGTTCACCATGACCACGGTGCCGATCGAATCGGTGGCCTTGAAGCTGTTCACCGGCATCGAGAAGT
TCGAGATCATGGCGATCCCGTTCTTCATTCTGGCGGGCAACTTCCTGACCCACGGCGGGGTCGCCAAGCGCATGATCAAT
TTCGCCACGGCGATGGTCGGCCATTGGTATGGCGGCCTGGGGCTGGGCGGCGTGGTCGCCTGCGCGCTGTTCGCCGCCAT
TTCGGGCTCGTCGCCGGCCACCGTCGTCGCCATCGGCTCGATCTTGCTGCCGGCGATGGTCAAGCAGGGCTTTCCCCGGC
GCTTCGGCGCCGGCGTCATCACCACCTCGGGCGCGCTTGGCATCCTGATCCCGCCGTCGCTGGTCATGGTGATGTACGCG
GTGGCGACCAACACCTCGGTCGGCGCCCTGTTCATGGCCGGCGTCGTCCCCGGGCTGGTGCTGGCCACCTTGCTGGGCGT
CACCACCTCGGTCATCGCCCGCAAGAACAACTATCCGCGCCTGCCCAAGGCGAGTTGGGCGACCCGGGCCAAGGCCTTCC
GCGAGGCGATCTGGGGCCTGATGCTGGTCGTCATCGTCATCGGCGGCATCTATTCCGGGATCTTCACCCCGACCGAAGCC
GCGGCGATGAGCGCCGTCTACGCCTTTCTGATCGCCGTCTTCGTCTATAAGGACATGCCGCTGCGCGGCGTGGTGAAGAT
CTTGCTGTCCTCGGCCTCGATGTCGGCGATGCTGCTCTACATCATCACCAACGCGGTGCTGTTCAGCTTCGTTCTGGCCA
ATGAGAACATTCCCCAGGCCATCGCCGACTGGATCGTCGGCAAGGAACTGGGCATCGTCGCCTTCTTGCTGGTGGTCAAC
GTCCTGCTGCTGGCGGCGGGCAATTTCATGGAGCCGTCATCGATCGTTCTGATCATGGCGCCTATTCTTTTCCCGGTGGC
GATGAAGCTGGGCATCGATCCGGTGCATTTCGGCATCCTGATCATCGTCAACATGGAGGTCGGCATGTGCCATCCGCCGG
TCGGGCTGAACCTCTATGTCGCCTCGGGCATTACCAAGATGGGAATATCCGAGCTGACGGTGGCGGTGATGCCCTGGCTG
CTGACCATGCTGGGCTTCCTGATCGTCGTCACCTATTGGCCGGGCCTGTCGCTGTGGCTGCCCCGGGCCCTGGGCATGAT
GTAG

Upstream 100 bases:

>100_bases
TCACCATGAACGACGGCCTCCATCCCAAGGACATCGCCCACGACGACGACACCGGGGACAAGCCAGATGATGGCACCGGA
ACCGGCAAGGGAGACGGCCG

Downstream 100 bases:

>100_bases
GGCCGTCGCGCCAAGAACCGCCACCATCAGGGGGACACGGGCGAAGGCCGGTGTCCCCTTTTTTCCGCCCGCCCCATCGG
CCCACCGTCCTGATCGTCGT

Product: TRAP dicarboxylate transporter subunit DctM

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 427; Mature: 426

Protein sequence:

>427_residues
MSALIIFTLLLCLMLTGMPISISLGLTVLTFLFTMTTVPIESVALKLFTGIEKFEIMAIPFFILAGNFLTHGGVAKRMIN
FATAMVGHWYGGLGLGGVVACALFAAISGSSPATVVAIGSILLPAMVKQGFPRRFGAGVITTSGALGILIPPSLVMVMYA
VATNTSVGALFMAGVVPGLVLATLLGVTTSVIARKNNYPRLPKASWATRAKAFREAIWGLMLVVIVIGGIYSGIFTPTEA
AAMSAVYAFLIAVFVYKDMPLRGVVKILLSSASMSAMLLYIITNAVLFSFVLANENIPQAIADWIVGKELGIVAFLLVVN
VLLLAAGNFMEPSSIVLIMAPILFPVAMKLGIDPVHFGILIIVNMEVGMCHPPVGLNLYVASGITKMGISELTVAVMPWL
LTMLGFLIVVTYWPGLSLWLPRALGMM

Sequences:

>Translated_427_residues
MSALIIFTLLLCLMLTGMPISISLGLTVLTFLFTMTTVPIESVALKLFTGIEKFEIMAIPFFILAGNFLTHGGVAKRMIN
FATAMVGHWYGGLGLGGVVACALFAAISGSSPATVVAIGSILLPAMVKQGFPRRFGAGVITTSGALGILIPPSLVMVMYA
VATNTSVGALFMAGVVPGLVLATLLGVTTSVIARKNNYPRLPKASWATRAKAFREAIWGLMLVVIVIGGIYSGIFTPTEA
AAMSAVYAFLIAVFVYKDMPLRGVVKILLSSASMSAMLLYIITNAVLFSFVLANENIPQAIADWIVGKELGIVAFLLVVN
VLLLAAGNFMEPSSIVLIMAPILFPVAMKLGIDPVHFGILIIVNMEVGMCHPPVGLNLYVASGITKMGISELTVAVMPWL
LTMLGFLIVVTYWPGLSLWLPRALGMM
>Mature_426_residues
SALIIFTLLLCLMLTGMPISISLGLTVLTFLFTMTTVPIESVALKLFTGIEKFEIMAIPFFILAGNFLTHGGVAKRMINF
ATAMVGHWYGGLGLGGVVACALFAAISGSSPATVVAIGSILLPAMVKQGFPRRFGAGVITTSGALGILIPPSLVMVMYAV
ATNTSVGALFMAGVVPGLVLATLLGVTTSVIARKNNYPRLPKASWATRAKAFREAIWGLMLVVIVIGGIYSGIFTPTEAA
AMSAVYAFLIAVFVYKDMPLRGVVKILLSSASMSAMLLYIITNAVLFSFVLANENIPQAIADWIVGKELGIVAFLLVVNV
LLLAAGNFMEPSSIVLIMAPILFPVAMKLGIDPVHFGILIIVNMEVGMCHPPVGLNLYVASGITKMGISELTVAVMPWLL
TMLGFLIVVTYWPGLSLWLPRALGMM

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=398, Percent_Identity=33.1658291457286, Blast_Score=218, Evalue=6e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 45223; Mature: 45092

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
6.1 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALIIFTLLLCLMLTGMPISISLGLTVLTFLFTMTTVPIESVALKLFTGIEKFEIMAIP
CHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHH
FFILAGNFLTHGGVAKRMINFATAMVGHWYGGLGLGGVVACALFAAISGSSPATVVAIGS
HHHHHCCHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHH
ILLPAMVKQGFPRRFGAGVITTSGALGILIPPSLVMVMYAVATNTSVGALFMAGVVPGLV
HHHHHHHHCCCCCHHCCCEEECCCCCEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LATLLGVTTSVIARKNNYPRLPKASWATRAKAFREAIWGLMLVVIVIGGIYSGIFTPTEA
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
AAMSAVYAFLIAVFVYKDMPLRGVVKILLSSASMSAMLLYIITNAVLFSFVLANENIPQA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
IADWIVGKELGIVAFLLVVNVLLLAAGNFMEPSSIVLIMAPILFPVAMKLGIDPVHFGIL
HHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHEEEE
IIVNMEVGMCHPPVGLNLYVASGITKMGISELTVAVMPWLLTMLGFLIVVTYWPGLSLWL
EEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
PRALGMM
HHHHCCC
>Mature Secondary Structure 
SALIIFTLLLCLMLTGMPISISLGLTVLTFLFTMTTVPIESVALKLFTGIEKFEIMAIP
HHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHH
FFILAGNFLTHGGVAKRMINFATAMVGHWYGGLGLGGVVACALFAAISGSSPATVVAIGS
HHHHHCCHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHH
ILLPAMVKQGFPRRFGAGVITTSGALGILIPPSLVMVMYAVATNTSVGALFMAGVVPGLV
HHHHHHHHCCCCCHHCCCEEECCCCCEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LATLLGVTTSVIARKNNYPRLPKASWATRAKAFREAIWGLMLVVIVIGGIYSGIFTPTEA
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
AAMSAVYAFLIAVFVYKDMPLRGVVKILLSSASMSAMLLYIITNAVLFSFVLANENIPQA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
IADWIVGKELGIVAFLLVVNVLLLAAGNFMEPSSIVLIMAPILFPVAMKLGIDPVHFGIL
HHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHEEEE
IIVNMEVGMCHPPVGLNLYVASGITKMGISELTVAVMPWLLTMLGFLIVVTYWPGLSLWL
EEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
PRALGMM
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]