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The map label for this gene is hrcA [H]

Identifier: 83594971

GI number: 83594971

Start: 4183002

End: 4184060

Strand: Direct

Name: hrcA [H]

Synonym: Rru_A3642

Alternate gene names: 83594971

Gene position: 4183002-4184060 (Clockwise)

Preceding gene: 83594967

Following gene: 83594972

Centisome position: 96.1

GC content: 64.21

Gene sequence:

>1059_bases
ATGGTGGTGACGGGTCGCGGCGGCATCGTGACCGAACTGGATGAGCGCTCCCGCCAGATCTTCGGCCAGATCGTGGAAAC
CTATGTGGAAACCGGCGAGCCGGTCGGCTCGCGCACCTTGTCGCGGCGCCTGACGGTGGCCCTGTCGCCCGCCACCATCC
GCAATGTCATGGCCGACCTTGAGGACTTGGGGCTGCTTTATGCCCCCCATACCTCGGCCGGGCGCCTGCCCACCGATGCC
GGGCTGCGCCTGTTCGTCAACGGCCTGATGGAATTGGGCGGGCTGACCTCGGAAGAGCGCCGCCATATCGATGGCCGGGT
TCAGGCCGCCGGCAAGAACCTTGACGACATGCTGAGCGACGCGACCTCGCTGCTGTCGGGGCTGGCGCGCTGCGCCGGGC
TGGTGCTCGCCCCCAAGACCGACAGCGCCCTCAAGCACATCGAATTCGTGCCGCTCGGCCCCGGGCGGGCGATGGTGATC
ATGATCACCGAAAACGGCCTTGTCGAAAACCGCGTGCTTGAGGTGCCCCAGGGCCTGCCGCCCAGCGCCCTGGCCGAGGC
CACCAATTACCTGAACGCCCGGCTGACCGGACGCACCCTGGAAGAGGCGCGCTCGGAGATTCAAGAGGAACTCGACAGCC
ATCGCAGCGCCCTGGACGATCTCGCCCAGCGCGTGGTCGAAACCGGCATGGCGACATGGTCGGGGGGGACGCGCGGCGGC
GAGCTGATCGTGCGCGGCCAAAGCCATCTTTTGGCCGATGTCACCGCCCTGGAGGATCTGGAACGCATCCGCGATCTGTT
CGATACCCTGGAAACCAAGGAACAGGTTCTGAGAATCCTTGATATGGTCAATCTGGCCGAGGGCGTTCAGATCTTTATCG
GAGCGGAGAACGAGTTGTTTTCCGTCTCGGGCTGCTCCATGATCGTCGCCCCTTATCAGAACAGCCGGGAAGAGATCGTT
GGCGCCATTGGCGTTATCGGTCCCACCCGCATCAATTACCGCCGCATCATTCCCTTGGTGGATTACACCTCCAAGGTGAT
CAGCCGGATGATCGGCTGA

Upstream 100 bases:

>100_bases
CGGCGCTCGCCCCGTTGACCGGGGGTCGGGAGCGCCCTACCTTGACGACAGGGTCCTTAAAGGGCGTCCCTTTAAGATCG
ACGGCAGGAGGTTGGGACCG

Downstream 100 bases:

>100_bases
AGCGGCTTTCCTTGAAACCCTGAAGACGACTGGAAGACGGAACGCGCCATGCCGCAGCACAACGACACGCCCGAAAGCCG
GACCCCTCAGGACTCGTCCG

Product: heat-inducible transcription repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MVVTGRGGIVTELDERSRQIFGQIVETYVETGEPVGSRTLSRRLTVALSPATIRNVMADLEDLGLLYAPHTSAGRLPTDA
GLRLFVNGLMELGGLTSEERRHIDGRVQAAGKNLDDMLSDATSLLSGLARCAGLVLAPKTDSALKHIEFVPLGPGRAMVI
MITENGLVENRVLEVPQGLPPSALAEATNYLNARLTGRTLEEARSEIQEELDSHRSALDDLAQRVVETGMATWSGGTRGG
ELIVRGQSHLLADVTALEDLERIRDLFDTLETKEQVLRILDMVNLAEGVQIFIGAENELFSVSGCSMIVAPYQNSREEIV
GAIGVIGPTRINYRRIIPLVDYTSKVISRMIG

Sequences:

>Translated_352_residues
MVVTGRGGIVTELDERSRQIFGQIVETYVETGEPVGSRTLSRRLTVALSPATIRNVMADLEDLGLLYAPHTSAGRLPTDA
GLRLFVNGLMELGGLTSEERRHIDGRVQAAGKNLDDMLSDATSLLSGLARCAGLVLAPKTDSALKHIEFVPLGPGRAMVI
MITENGLVENRVLEVPQGLPPSALAEATNYLNARLTGRTLEEARSEIQEELDSHRSALDDLAQRVVETGMATWSGGTRGG
ELIVRGQSHLLADVTALEDLERIRDLFDTLETKEQVLRILDMVNLAEGVQIFIGAENELFSVSGCSMIVAPYQNSREEIV
GAIGVIGPTRINYRRIIPLVDYTSKVISRMIG
>Mature_352_residues
MVVTGRGGIVTELDERSRQIFGQIVETYVETGEPVGSRTLSRRLTVALSPATIRNVMADLEDLGLLYAPHTSAGRLPTDA
GLRLFVNGLMELGGLTSEERRHIDGRVQAAGKNLDDMLSDATSLLSGLARCAGLVLAPKTDSALKHIEFVPLGPGRAMVI
MITENGLVENRVLEVPQGLPPSALAEATNYLNARLTGRTLEEARSEIQEELDSHRSALDDLAQRVVETGMATWSGGTRGG
ELIVRGQSHLLADVTALEDLERIRDLFDTLETKEQVLRILDMVNLAEGVQIFIGAENELFSVSGCSMIVAPYQNSREEIV
GAIGVIGPTRINYRRIIPLVDYTSKVISRMIG

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons [H]

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01628 HrcA [H]

EC number: NA

Molecular weight: Translated: 38183; Mature: 38183

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVTGRGGIVTELDERSRQIFGQIVETYVETGEPVGSRTLSRRLTVALSPATIRNVMADL
CEEECCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHEEEEECHHHHHHHHHHH
EDLGLLYAPHTSAGRLPTDAGLRLFVNGLMELGGLTSEERRHIDGRVQAAGKNLDDMLSD
HHCCEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHCCCHHHHCCCCHHHHHHH
ATSLLSGLARCAGLVLAPKTDSALKHIEFVPLGPGRAMVIMITENGLVENRVLEVPQGLP
HHHHHHHHHHHHCEEECCCCCHHHHHEEEEECCCCCEEEEEEECCCCHHHHHHHCCCCCC
PSALAEATNYLNARLTGRTLEEARSEIQEELDSHRSALDDLAQRVVETGMATWSGGTRGG
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
ELIVRGQSHLLADVTALEDLERIRDLFDTLETKEQVLRILDMVNLAEGVQIFIGAENELF
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEE
SVSGCSMIVAPYQNSREEIVGAIGVIGPTRINYRRIIPLVDYTSKVISRMIG
EECCCEEEEECCCCCHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVVTGRGGIVTELDERSRQIFGQIVETYVETGEPVGSRTLSRRLTVALSPATIRNVMADL
CEEECCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHEEEEECHHHHHHHHHHH
EDLGLLYAPHTSAGRLPTDAGLRLFVNGLMELGGLTSEERRHIDGRVQAAGKNLDDMLSD
HHCCEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHCCCHHHHCCCCHHHHHHH
ATSLLSGLARCAGLVLAPKTDSALKHIEFVPLGPGRAMVIMITENGLVENRVLEVPQGLP
HHHHHHHHHHHHCEEECCCCCHHHHHEEEEECCCCCEEEEEEECCCCHHHHHHHCCCCCC
PSALAEATNYLNARLTGRTLEEARSEIQEELDSHRSALDDLAQRVVETGMATWSGGTRGG
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
ELIVRGQSHLLADVTALEDLERIRDLFDTLETKEQVLRILDMVNLAEGVQIFIGAENELF
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEE
SVSGCSMIVAPYQNSREEIVGAIGVIGPTRINYRRIIPLVDYTSKVISRMIG
EECCCEEEEECCCCCHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA