Click here to switch to the map view.

The map label for this gene is ycfF [C]

Identifier: 83594921

GI number: 83594921

Start: 4135603

End: 4135965

Strand: Reverse

Name: ycfF [C]

Synonym: Rru_A3592

Alternate gene names: 83594921

Gene position: 4135965-4135603 (Counterclockwise)

Preceding gene: 83594922

Following gene: 83594920

Centisome position: 95.02

GC content: 64.74

Gene sequence:

>363_bases
ATGGCCTATGACGACAGCAATATCTTCGCCCGCATCCTGCGCGGGGAAATCCCCTGCGATAAGGTTTTCGAAGACGATCA
CGTTCTCGCCTTCCGCGACATCAATCCCCAGGCGCCCGTCCATGTTCTGGTGATTCCCAAGGGTCCCTATCGTTCGTGGA
CCGAGTTCTCGGCCACGGCCTCCGATGGCGAAATCGCCGCCCTGGTGCGCGCCGTCGGCACGGTCGCGGCCGACCTCGGT
GTGGTCGAGCAGGGCTACCGGGTGCTCTCCAACATCGGCGCCGATGGCGGCCAGGAAGTGCCCCATCTGCATTTGCACCT
GTTCGGCGGCCGACGCCTGGGGCGGATGATCGCCGCCGACTAG

Upstream 100 bases:

>100_bases
CGATCGGGTCTGGGCCGAATTGGCCCGCCGCTTCGGCACCTCGGGCATCGACGAGAAAGCCGCCCGCAAGAAGTGACCCT
GTCTTTCCGGAGCAGTCCCC

Downstream 100 bases:

>100_bases
CCTCCCACCCTAGAAAACCCCCTCGCCTTCACCATCTTTGGCTGTGTCCTCCCGGAGACTTCCTGTCGGGGGACCGGCCG
AAGATGTTCGAGGGGGGACG

Product: histidine triad (HIT) protein

Products: ADP

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 120; Mature: 119

Protein sequence:

>120_residues
MAYDDSNIFARILRGEIPCDKVFEDDHVLAFRDINPQAPVHVLVIPKGPYRSWTEFSATASDGEIAALVRAVGTVAADLG
VVEQGYRVLSNIGADGGQEVPHLHLHLFGGRRLGRMIAAD

Sequences:

>Translated_120_residues
MAYDDSNIFARILRGEIPCDKVFEDDHVLAFRDINPQAPVHVLVIPKGPYRSWTEFSATASDGEIAALVRAVGTVAADLG
VVEQGYRVLSNIGADGGQEVPHLHLHLFGGRRLGRMIAAD
>Mature_119_residues
AYDDSNIFARILRGEIPCDKVFEDDHVLAFRDINPQAPVHVLVIPKGPYRSWTEFSATASDGEIAALVRAVGTVAADLGV
VEQGYRVLSNIGADGGQEVPHLHLHLFGGRRLGRMIAAD

Specific function: Unknown

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Homo sapiens, GI4885413, Length=109, Percent_Identity=47.7064220183486, Blast_Score=98, Evalue=2e-21,
Organism=Homo sapiens, GI14211923, Length=107, Percent_Identity=42.0560747663551, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1787346, Length=114, Percent_Identity=43.859649122807, Blast_Score=96, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17506713, Length=109, Percent_Identity=45.8715596330275, Blast_Score=95, Evalue=7e-21,
Organism=Drosophila melanogaster, GI28574010, Length=113, Percent_Identity=45.1327433628319, Blast_Score=94, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24581222, Length=113, Percent_Identity=45.1327433628319, Blast_Score=94, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR019808
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: 3.6.1.41

Molecular weight: Translated: 13023; Mature: 12892

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS00892 HIT_1 ; PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYDDSNIFARILRGEIPCDKVFEDDHVLAFRDINPQAPVHVLVIPKGPYRSWTEFSATA
CCCCCHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCEEEEEEECCCCCCCCCCCCCC
SDGEIAALVRAVGTVAADLGVVEQGYRVLSNIGADGGQEVPHLHLHLFGGRRLGRMIAAD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCHHCCCC
>Mature Secondary Structure 
AYDDSNIFARILRGEIPCDKVFEDDHVLAFRDINPQAPVHVLVIPKGPYRSWTEFSATA
CCCCHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCEEEEEEECCCCCCCCCCCCCC
SDGEIAALVRAVGTVAADLGVVEQGYRVLSNIGADGGQEVPHLHLHLFGGRRLGRMIAAD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: P1,P4-bis(5'-adenosyl) tetraphosphate; H2O

Specific reaction: P1,P4-bis(5'-adenosyl) tetraphosphate + H2O = 2 ADP

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2664449; 1472710 [H]