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The map label for this gene is trpS [H]

Identifier: 83594864

GI number: 83594864

Start: 4066271

End: 4067269

Strand: Reverse

Name: trpS [H]

Synonym: Rru_A3535

Alternate gene names: 83594864

Gene position: 4067269-4066271 (Counterclockwise)

Preceding gene: 83594867

Following gene: 83594863

Centisome position: 93.44

GC content: 63.56

Gene sequence:

>999_bases
ATGGCTCGTATCTTCTCGGGCGTTCAGCCCACCGGTAATCTGCATCTGGGCAACTATCTGGGGGCCATCCGTAATTGGGT
GAAGCTCCAGACCGAATACGACTGCCTGTTCTGCATGGCCGATCAGCATGCGATCACCGTTTGGCAGGACCCCGAAACCC
TGCGCCGCCACACCCGCGAGGTCACCGCCGGGCTTTTAGCGGCCGGCATCGATCCCAAGCGCAACATCGTGTTCAACCAG
TCGACCGTACCCGCCCATGCCCAGCTCGCCTGGGTGTTCAATTGCGTGGCGCGCATGGGCTGGCTGAGCCGGATGACCCA
GTTCAAGGACAAGGCGGGCAAGCACAAGGAGAACGCCTCGGTCGGGCTGTTCGCCTATCCCGACCTGATGGCCGCCGATA
TCTTGCTCTATAAGGCCACCCATGTGCCGGTCGGCGAGGATCAGAAGCAGCATCTGGAGTTGACCCGCGACATCGCCCAG
AAGTTCAACAACGACTTCGGCGTCGAGCTGTTCCCGCTGCCCGAGCCGCTGACCCTGGGCGAGGCGACGCGGGTGATGTC
CCTGCGCGACGGCACCAAGAAGATGAGCAAGTCCGACGAGTCGGATTATTCGCGCATCAATATGACCGACGACGCCGATG
CCATCGCCCAGAAGCTGCGCAAGGCCAAGACCGATCCCGAGCCGCTGCCCGAAAGCGTCGAGGGCCTGAGCGGCCGGCCC
GAGGCCGCCAATCTGGTCGGCATCTATGCCGCGCTGTCGGATCTGTCGAAGGCCGATGTTTTGGCCAAGGTCGGCGGTCA
GCCGTTCAGCACCTTCAAGCAGGATCTGACCGATCTGGCGGTTTCGGTTTTGCAGCCGATCAACACGGAAATGGCCCGGC
TGCTTGCCGATCCGGCTTCGGTTGACGCCGTGCTGCGCGACGGCGCCGAACGCGCCGGGGCGATCGCCGAGCCGATCCTG
GCCGAGGTTTATGACACCGTCGGCTTCCTGCGCCCCTGA

Upstream 100 bases:

>100_bases
AACTTACCCGTAAGGCCTGCAGAATTCCAGAGGCTTGACCGATGGGGGGGAATCGTCTACGCCGCGCCGATCCCTTTCCC
AGGACTCGAGGCGCCGTCGC

Downstream 100 bases:

>100_bases
GGCCTTGCGCCAACGCCCCCCGCTCTCCGGAACCGATGAAGTCTGGCCGACGTTGCTTCGCCAGACTTCATCGCTTCCAG
CGGGGGCTTGCGCGTCATGT

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MARIFSGVQPTGNLHLGNYLGAIRNWVKLQTEYDCLFCMADQHAITVWQDPETLRRHTREVTAGLLAAGIDPKRNIVFNQ
STVPAHAQLAWVFNCVARMGWLSRMTQFKDKAGKHKENASVGLFAYPDLMAADILLYKATHVPVGEDQKQHLELTRDIAQ
KFNNDFGVELFPLPEPLTLGEATRVMSLRDGTKKMSKSDESDYSRINMTDDADAIAQKLRKAKTDPEPLPESVEGLSGRP
EAANLVGIYAALSDLSKADVLAKVGGQPFSTFKQDLTDLAVSVLQPINTEMARLLADPASVDAVLRDGAERAGAIAEPIL
AEVYDTVGFLRP

Sequences:

>Translated_332_residues
MARIFSGVQPTGNLHLGNYLGAIRNWVKLQTEYDCLFCMADQHAITVWQDPETLRRHTREVTAGLLAAGIDPKRNIVFNQ
STVPAHAQLAWVFNCVARMGWLSRMTQFKDKAGKHKENASVGLFAYPDLMAADILLYKATHVPVGEDQKQHLELTRDIAQ
KFNNDFGVELFPLPEPLTLGEATRVMSLRDGTKKMSKSDESDYSRINMTDDADAIAQKLRKAKTDPEPLPESVEGLSGRP
EAANLVGIYAALSDLSKADVLAKVGGQPFSTFKQDLTDLAVSVLQPINTEMARLLADPASVDAVLRDGAERAGAIAEPIL
AEVYDTVGFLRP
>Mature_331_residues
ARIFSGVQPTGNLHLGNYLGAIRNWVKLQTEYDCLFCMADQHAITVWQDPETLRRHTREVTAGLLAAGIDPKRNIVFNQS
TVPAHAQLAWVFNCVARMGWLSRMTQFKDKAGKHKENASVGLFAYPDLMAADILLYKATHVPVGEDQKQHLELTRDIAQK
FNNDFGVELFPLPEPLTLGEATRVMSLRDGTKKMSKSDESDYSRINMTDDADAIAQKLRKAKTDPEPLPESVEGLSGRPE
AANLVGIYAALSDLSKADVLAKVGGQPFSTFKQDLTDLAVSVLQPINTEMARLLADPASVDAVLRDGAERAGAIAEPILA
EVYDTVGFLRP

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=329, Percent_Identity=45.5927051671732, Blast_Score=290, Evalue=1e-78,
Organism=Homo sapiens, GI41352700, Length=176, Percent_Identity=56.25, Blast_Score=214, Evalue=9e-56,
Organism=Escherichia coli, GI1789786, Length=327, Percent_Identity=45.2599388379205, Blast_Score=303, Evalue=7e-84,
Organism=Caenorhabditis elegans, GI71982800, Length=337, Percent_Identity=37.9821958456973, Blast_Score=219, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI71982793, Length=337, Percent_Identity=37.9821958456973, Blast_Score=218, Evalue=4e-57,
Organism=Saccharomyces cerevisiae, GI6320474, Length=350, Percent_Identity=40, Blast_Score=232, Evalue=6e-62,
Organism=Drosophila melanogaster, GI24666151, Length=330, Percent_Identity=38.4848484848485, Blast_Score=226, Evalue=1e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 36462; Mature: 36331

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARIFSGVQPTGNLHLGNYLGAIRNWVKLQTEYDCLFCMADQHAITVWQDPETLRRHTRE
CCCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEECCHHHHHHHHHH
VTAGLLAAGIDPKRNIVFNQSTVPAHAQLAWVFNCVARMGWLSRMTQFKDKAGKHKENAS
HHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
VGLFAYPDLMAADILLYKATHVPVGEDQKQHLELTRDIAQKFNNDFGVELFPLPEPLTLG
EEEEECCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCC
EATRVMSLRDGTKKMSKSDESDYSRINMTDDADAIAQKLRKAKTDPEPLPESVEGLSGRP
HHHHHHHHHHHHHHHHCCCCCCCCEECCCCCHHHHHHHHHHCCCCCCCCCHHHHCCCCCC
EAANLVGIYAALSDLSKADVLAKVGGQPFSTFKQDLTDLAVSVLQPINTEMARLLADPAS
CHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHH
VDAVLRDGAERAGAIAEPILAEVYDTVGFLRP
HHHHHHCCHHHCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ARIFSGVQPTGNLHLGNYLGAIRNWVKLQTEYDCLFCMADQHAITVWQDPETLRRHTRE
CCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEECCHHHHHHHHHH
VTAGLLAAGIDPKRNIVFNQSTVPAHAQLAWVFNCVARMGWLSRMTQFKDKAGKHKENAS
HHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
VGLFAYPDLMAADILLYKATHVPVGEDQKQHLELTRDIAQKFNNDFGVELFPLPEPLTLG
EEEEECCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCC
EATRVMSLRDGTKKMSKSDESDYSRINMTDDADAIAQKLRKAKTDPEPLPESVEGLSGRP
HHHHHHHHHHHHHHHHCCCCCCCCEECCCCCHHHHHHHHHHCCCCCCCCCHHHHCCCCCC
EAANLVGIYAALSDLSKADVLAKVGGQPFSTFKQDLTDLAVSVLQPINTEMARLLADPAS
CHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHH
VDAVLRDGAERAGAIAEPILAEVYDTVGFLRP
HHHHHHCCHHHCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]