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The map label for this gene is dinB [H]

Identifier: 83594859

GI number: 83594859

Start: 4061767

End: 4063032

Strand: Direct

Name: dinB [H]

Synonym: Rru_A3530

Alternate gene names: 83594859

Gene position: 4061767-4063032 (Clockwise)

Preceding gene: 83594853

Following gene: 83594865

Centisome position: 93.31

GC content: 69.27

Gene sequence:

>1266_bases
ATGACCGGCCTCTGTCGCGACTGTCTATGCGAGGTGCTGACACCCAGCGGATGCTGTCCGGGCTGCGGATCGGCGCGGGT
GGTTCGCCATCCCGGGCTCGCCCTTCTGGATATCGCCCATATCGACTGCGACGCCTTTTACGCCTCGGTGGAAAAGCGCG
ACAATCCCAGCCTGCGCGACCGACCGCTGATCGTTGGCCATCCCGGCGGCCGCGGCGTGGCGACGACGGCCTGTTACATC
GCCCGGCGCTTTGGCGCGCGCTCGGCGATGCCGATGTTCAAATGCCTGGAGCTCTGCCCCGAGGCCGTGGTCATCCCCCC
CGATATGGCGAAATACAAGGCCGTCAGCGCCCAGGTGCGGGCGATCATGCTCGAGGCGACGCATAGGCTGGAGCCGCTGT
CGCTTGACGAGGCCTATCTGGATCTTTCCGAAGGCGAACACCGTTTCGCCCGGCCGCCGGCGGTCAGTTTGGCGACGATC
GCCCGCCGGGTCGAGCGCGAGATCGGCATCACCGTGTCGATCGGGCTGTCCTCGAACCGTTTCCTGGCCAAGCTGGCCAG
CGACATGAACAAGCCCCAGGGGTTCACCGTGATCGACGAGGCCGAGGCCCCGGCCCTGCTGGCGCCGATGCCGGTCAAAC
GCCTGCATGGGGTGGGAGCGGCGACCGAACGCCGGTTGGCCGAATTGGGCCTGCACACCATCGGCGATCTTCAGGGCCGG
CCCGAGGCCGATTTGCTCGCCCGCTTTGGTAAGATCGGCCGGGCGCTGCACGCCCACGCCTGGGGGCGGGGCGGCCGGAC
GATCAGCCCCGATCGCGAAACCAAAAGCATCTCGGCCGAAACCACCTTCGAGCGCGATCTGTCGCGCCTGCCCGATCTCG
CCCGCGCCCTGGGCCCGTTAAGCGAGCGCGTGGCCCGCGCCCTGACCCGCAACGCCCTGGCCGGGGCGACGGTGGTGCTG
AAGCTCAAGACCCATGACTTCCGCATCCTGACCCGTCACGCCCGCTTGGGCGACCCGACCGCCCGGGCCGAGGTGATCGC
CGGCGCCGCCCGGCGTTTGCTTGAACGCGAAACCGATGGCCGGCGCTTTCGCCTAATCGGGGTGGGCATGGCCGACCTGC
GCCCGGGCAGCGAGGCCGATCCCCCCGATCTATTCGCCCGCTCCCCGCCGACGGCACGCGACGCACCGGCCGGCAAGGAG
ACGGGCGATGGCGGGTCGGAAAGCCCTCAGAGGACCGCTTCGACCGCCTCGACCTCGGGAATGTAG

Upstream 100 bases:

>100_bases
GGCGGGTCACGGAATCATCGCCGGGCGGCCCGCTCTTCCGCCATAAGAACATTTAGGGTACATTGGCGGACCCCGCCCCG
GAAAACCAGCGGATTTCCCC

Downstream 100 bases:

>100_bases
TGGCGCAGCATGTTTTCGATGCCGTGCTTGAGGGTGGCGGTGGAACTGGGGCAGCCCGAGCACGAGCCGCGCAGGTGCAG
ATAGACGACGCCATCCTGGA

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 421; Mature: 420

Protein sequence:

>421_residues
MTGLCRDCLCEVLTPSGCCPGCGSARVVRHPGLALLDIAHIDCDAFYASVEKRDNPSLRDRPLIVGHPGGRGVATTACYI
ARRFGARSAMPMFKCLELCPEAVVIPPDMAKYKAVSAQVRAIMLEATHRLEPLSLDEAYLDLSEGEHRFARPPAVSLATI
ARRVEREIGITVSIGLSSNRFLAKLASDMNKPQGFTVIDEAEAPALLAPMPVKRLHGVGAATERRLAELGLHTIGDLQGR
PEADLLARFGKIGRALHAHAWGRGGRTISPDRETKSISAETTFERDLSRLPDLARALGPLSERVARALTRNALAGATVVL
KLKTHDFRILTRHARLGDPTARAEVIAGAARRLLERETDGRRFRLIGVGMADLRPGSEADPPDLFARSPPTARDAPAGKE
TGDGGSESPQRTASTASTSGM

Sequences:

>Translated_421_residues
MTGLCRDCLCEVLTPSGCCPGCGSARVVRHPGLALLDIAHIDCDAFYASVEKRDNPSLRDRPLIVGHPGGRGVATTACYI
ARRFGARSAMPMFKCLELCPEAVVIPPDMAKYKAVSAQVRAIMLEATHRLEPLSLDEAYLDLSEGEHRFARPPAVSLATI
ARRVEREIGITVSIGLSSNRFLAKLASDMNKPQGFTVIDEAEAPALLAPMPVKRLHGVGAATERRLAELGLHTIGDLQGR
PEADLLARFGKIGRALHAHAWGRGGRTISPDRETKSISAETTFERDLSRLPDLARALGPLSERVARALTRNALAGATVVL
KLKTHDFRILTRHARLGDPTARAEVIAGAARRLLERETDGRRFRLIGVGMADLRPGSEADPPDLFARSPPTARDAPAGKE
TGDGGSESPQRTASTASTSGM
>Mature_420_residues
TGLCRDCLCEVLTPSGCCPGCGSARVVRHPGLALLDIAHIDCDAFYASVEKRDNPSLRDRPLIVGHPGGRGVATTACYIA
RRFGARSAMPMFKCLELCPEAVVIPPDMAKYKAVSAQVRAIMLEATHRLEPLSLDEAYLDLSEGEHRFARPPAVSLATIA
RRVEREIGITVSIGLSSNRFLAKLASDMNKPQGFTVIDEAEAPALLAPMPVKRLHGVGAATERRLAELGLHTIGDLQGRP
EADLLARFGKIGRALHAHAWGRGGRTISPDRETKSISAETTFERDLSRLPDLARALGPLSERVARALTRNALAGATVVLK
LKTHDFRILTRHARLGDPTARAEVIAGAARRLLERETDGRRFRLIGVGMADLRPGSEADPPDLFARSPPTARDAPAGKET
GDGGSESPQRTASTASTSGM

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=338, Percent_Identity=26.0355029585799, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI7706681, Length=339, Percent_Identity=25.9587020648968, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI7705344, Length=107, Percent_Identity=47.6635514018692, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI154350220, Length=331, Percent_Identity=25.3776435045317, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI5729982, Length=122, Percent_Identity=32.7868852459016, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1786425, Length=346, Percent_Identity=38.4393063583815, Blast_Score=208, Evalue=5e-55,
Organism=Escherichia coli, GI1787432, Length=214, Percent_Identity=28.5046728971963, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193205700, Length=398, Percent_Identity=30.9045226130653, Blast_Score=159, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI193205702, Length=345, Percent_Identity=28.4057971014493, Blast_Score=111, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17537959, Length=350, Percent_Identity=23.4285714285714, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI19923006, Length=335, Percent_Identity=25.6716417910448, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI21355641, Length=281, Percent_Identity=28.1138790035587, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24644984, Length=281, Percent_Identity=28.1138790035587, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 45171; Mature: 45040

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGLCRDCLCEVLTPSGCCPGCGSARVVRHPGLALLDIAHIDCDAFYASVEKRDNPSLRD
CCCHHHHHHHHHCCCCCCCCCCCCCEEEECCCEEEEEEECCCHHHHHHHHHCCCCCCCCC
RPLIVGHPGGRGVATTACYIARRFGARSAMPMFKCLELCPEAVVIPPDMAKYKAVSAQVR
CCEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEECCCHHHHHHHHHHHH
AIMLEATHRLEPLSLDEAYLDLSEGEHRFARPPAVSLATIARRVEREIGITVSIGLSSNR
HHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCH
FLAKLASDMNKPQGFTVIDEAEAPALLAPMPVKRLHGVGAATERRLAELGLHTIGDLQGR
HHHHHHHHCCCCCCCEEEECCCCCEEECCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCCC
PEADLLARFGKIGRALHAHAWGRGGRTISPDRETKSISAETTFERDLSRLPDLARALGPL
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHCHH
SERVARALTRNALAGATVVLKLKTHDFRILTRHARLGDPTARAEVIAGAARRLLERETDG
HHHHHHHHHHHHHCCEEEEEEEECCCEEEEEHHHHCCCCHHHHHHHHHHHHHHHHCCCCC
RRFRLIGVGMADLRPGSEADPPDLFARSPPTARDAPAGKETGDGGSESPQRTASTASTSG
CEEEEEECCHHHCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCC
M
C
>Mature Secondary Structure 
TGLCRDCLCEVLTPSGCCPGCGSARVVRHPGLALLDIAHIDCDAFYASVEKRDNPSLRD
CCHHHHHHHHHCCCCCCCCCCCCCEEEECCCEEEEEEECCCHHHHHHHHHCCCCCCCCC
RPLIVGHPGGRGVATTACYIARRFGARSAMPMFKCLELCPEAVVIPPDMAKYKAVSAQVR
CCEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEECCCHHHHHHHHHHHH
AIMLEATHRLEPLSLDEAYLDLSEGEHRFARPPAVSLATIARRVEREIGITVSIGLSSNR
HHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCH
FLAKLASDMNKPQGFTVIDEAEAPALLAPMPVKRLHGVGAATERRLAELGLHTIGDLQGR
HHHHHHHHCCCCCCCEEEECCCCCEEECCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCCC
PEADLLARFGKIGRALHAHAWGRGGRTISPDRETKSISAETTFERDLSRLPDLARALGPL
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHCHH
SERVARALTRNALAGATVVLKLKTHDFRILTRHARLGDPTARAEVIAGAARRLLERETDG
HHHHHHHHHHHHHCCEEEEEEEECCCEEEEEHHHHCCCCHHHHHHHHHHHHHHHHCCCCC
RRFRLIGVGMADLRPGSEADPPDLFARSPPTARDAPAGKETGDGGSESPQRTASTASTSG
CEEEEEECCHHHCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCC
M
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]