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The map label for this gene is yeiG [H]

Identifier: 83594735

GI number: 83594735

Start: 3922927

End: 3923775

Strand: Direct

Name: yeiG [H]

Synonym: Rru_A3406

Alternate gene names: 83594735

Gene position: 3922927-3923775 (Clockwise)

Preceding gene: 83594734

Following gene: 83594736

Centisome position: 90.12

GC content: 68.79

Gene sequence:

>849_bases
ATGACCGGGGCCCCCCAGCTTGTCTCGGCCGCGTGCTGCTTTGGCGGCACCCAGGCGCGTTATCGCCATTCCTCGGCGGT
CCTTGGCTGCGAGATGGTGTTTTCGCTGTTCCTGCCGCCCCGGGCGGCGGACCAATCGGTGCCGGCGGCCTATTGGCTGT
CGGGGCTGACCTGCACCGACGAGAATTTCGTCCAGAAGGCCGGGGCCCAGCGGGTCGCCGCCGAGTTGGGGATCGCCCTG
GTCGTGCCCGACACCAGCCCGCGTGGTCCGGGCGTTGCCGATGATCCCGAGGGCGCCTATGACTTCGGCTTGGGGGCCGG
GTTCTATCTGGACGCCAGCCGCGAGCCCTTCGCCCGCCACTACCGCATGGGCGACTACGTGGCCGCCGAGCTTCCCGCCC
TGATCGAGGCCCATTTCCCGATCGATGGGCGCCGGGCGGTTTTTGGGCATTCCATGGGCGGCCATGGCGCCTTGGTCACG
GCGCTGCGTCACCCCGGGCGCTATCGTTCGGTCTCGGCTTTCGCCCCGATCACCAATCCGATGGCCTGTCCCTGGGGCGA
AAAGGCCTTCACCGGCTATCTGGGGGAGGACCGCGCCTTGTGGCGGCCGTGGGACGCCTGCGCGCTGATCGAAAGCGCGC
CCGAGCGCCTGCCGCTGCTGGTCGATCAGGGCACGGCCGACGCGTTCCTTGAGACCCAGTTGCGCCCCCGGGCCCTGGAA
GCGGCCTGCAGGGCGGCTGGTCATCCGTTAACGCTGCGCCTGCGCCAAGGCTATGATCACAGCTATTTCTTCATCGCCTC
CTTCATCGAGGATCACCTGCGCTTCCACGCCCGCGCCCTGGCCGAATAG

Upstream 100 bases:

>100_bases
GGCCGACATCAACCACGCCTTCGAGCTGATGCACGAGGGCAAAAGCATCCGCTCGGTGATCCATTATGACCTGTGATCTC
CGCCGGTCGGAGGACCGGCA

Downstream 100 bases:

>100_bases
GGCAGAATCTCCGCGCTCCGCCGACCCGCGCCAAAGCCGCTTGGTTTGGTGCGCTTCGATATGGATTCAATAAGATAGGG
CGGCGCGGCCGTGGAAAACC

Product: carboxylesterase

Products: NA

Alternate protein names: FGH [H]

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MTGAPQLVSAACCFGGTQARYRHSSAVLGCEMVFSLFLPPRAADQSVPAAYWLSGLTCTDENFVQKAGAQRVAAELGIAL
VVPDTSPRGPGVADDPEGAYDFGLGAGFYLDASREPFARHYRMGDYVAAELPALIEAHFPIDGRRAVFGHSMGGHGALVT
ALRHPGRYRSVSAFAPITNPMACPWGEKAFTGYLGEDRALWRPWDACALIESAPERLPLLVDQGTADAFLETQLRPRALE
AACRAAGHPLTLRLRQGYDHSYFFIASFIEDHLRFHARALAE

Sequences:

>Translated_282_residues
MTGAPQLVSAACCFGGTQARYRHSSAVLGCEMVFSLFLPPRAADQSVPAAYWLSGLTCTDENFVQKAGAQRVAAELGIAL
VVPDTSPRGPGVADDPEGAYDFGLGAGFYLDASREPFARHYRMGDYVAAELPALIEAHFPIDGRRAVFGHSMGGHGALVT
ALRHPGRYRSVSAFAPITNPMACPWGEKAFTGYLGEDRALWRPWDACALIESAPERLPLLVDQGTADAFLETQLRPRALE
AACRAAGHPLTLRLRQGYDHSYFFIASFIEDHLRFHARALAE
>Mature_281_residues
TGAPQLVSAACCFGGTQARYRHSSAVLGCEMVFSLFLPPRAADQSVPAAYWLSGLTCTDENFVQKAGAQRVAAELGIALV
VPDTSPRGPGVADDPEGAYDFGLGAGFYLDASREPFARHYRMGDYVAAELPALIEAHFPIDGRRAVFGHSMGGHGALVTA
LRHPGRYRSVSAFAPITNPMACPWGEKAFTGYLGEDRALWRPWDACALIESAPERLPLLVDQGTADAFLETQLRPRALEA
ACRAAGHPLTLRLRQGYDHSYFFIASFIEDHLRFHARALAE

Specific function: Serine hydrolase involved in the detoxification of formaldehyde. Hydrolyzes S-formylglutathione to glutathione and formate [H]

COG id: COG0627

COG function: function code R; Predicted esterase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the esterase D family [H]

Homologues:

Organism=Homo sapiens, GI33413400, Length=280, Percent_Identity=52.5, Blast_Score=320, Evalue=7e-88,
Organism=Escherichia coli, GI1788477, Length=270, Percent_Identity=60.3703703703704, Blast_Score=335, Evalue=2e-93,
Organism=Escherichia coli, GI1786551, Length=275, Percent_Identity=48.3636363636364, Blast_Score=290, Evalue=9e-80,
Organism=Caenorhabditis elegans, GI17510185, Length=284, Percent_Identity=46.4788732394366, Blast_Score=263, Evalue=1e-70,
Organism=Saccharomyces cerevisiae, GI6322393, Length=299, Percent_Identity=42.4749163879599, Blast_Score=240, Evalue=1e-64,
Organism=Drosophila melanogaster, GI45551932, Length=283, Percent_Identity=51.5901060070671, Blast_Score=283, Evalue=7e-77,
Organism=Drosophila melanogaster, GI24648347, Length=283, Percent_Identity=51.5901060070671, Blast_Score=283, Evalue=7e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000801
- InterPro:   IPR014186 [H]

Pfam domain/function: PF00756 Esterase [H]

EC number: =3.1.2.12 [H]

Molecular weight: Translated: 30568; Mature: 30437

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGAPQLVSAACCFGGTQARYRHSSAVLGCEMVFSLFLPPRAADQSVPAAYWLSGLTCTD
CCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCEECC
ENFVQKAGAQRVAAELGIALVVPDTSPRGPGVADDPEGAYDFGLGAGFYLDASREPFARH
HHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCEECCCCCCEEECCCCCHHHHH
YRMGDYVAAELPALIEAHFPIDGRRAVFGHSMGGHGALVTALRHPGRYRSVSAFAPITNP
HCCCCHHHHHHHHHHEECCCCCCCEEEECCCCCCCHHHHHHHHCCCCCCCEEEECCCCCC
MACPWGEKAFTGYLGEDRALWRPWDACALIESAPERLPLLVDQGTADAFLETQLRPRALE
CCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHCCHHHCCEEEECCCHHHHHHHCCCHHHHH
AACRAAGHPLTLRLRQGYDHSYFFIASFIEDHLRFHARALAE
HHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TGAPQLVSAACCFGGTQARYRHSSAVLGCEMVFSLFLPPRAADQSVPAAYWLSGLTCTD
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCEECC
ENFVQKAGAQRVAAELGIALVVPDTSPRGPGVADDPEGAYDFGLGAGFYLDASREPFARH
HHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCEECCCCCCEEECCCCCHHHHH
YRMGDYVAAELPALIEAHFPIDGRRAVFGHSMGGHGALVTALRHPGRYRSVSAFAPITNP
HCCCCHHHHHHHHHHEECCCCCCCEEEECCCCCCCHHHHHHHHCCCCCCCEEEECCCCCC
MACPWGEKAFTGYLGEDRALWRPWDACALIESAPERLPLLVDQGTADAFLETQLRPRALE
CCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHCCHHHCCEEEECCCHHHHHHHCCCHHHHH
AACRAAGHPLTLRLRQGYDHSYFFIASFIEDHLRFHARALAE
HHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA